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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli CFT073  c3080  AAN81529.1  Q8FF26  purL  1295 aa Phosphoribosylformylglycinamidine synthase n.s. ●○○○○ -0.77 -0.765091642997745
Escherichia coli CFT073  c1460  AAN79929.1  A0A0H2V7I1  853 aa Putative tail component of prophage n.s. ●○○○○ -0.76 -0.76327178899378
Escherichia coli CFT073  c0562  AAN79040.1  Q8FKA2  cof  276 aa Cof protein n.s. ●○○○○ -0.76 -0.760836675121144
Escherichia coli CFT073  c0636  AAN79113.1  A0A0H2V5N2  purK  355 aa Phosphoribosylaminoimidazole carboxylase ATPase subunit n.s. ●○○○○ -0.76 -0.759859918919609
Escherichia coli CFT073  c0902  AAN79375.1  A0A0H2V7K0  42 aa Hypothetical protein n.s. ●○○○○ -0.76 -0.759595308114445
Escherichia coli CFT073  c4233  AAN82669.1  A0A0H2VE97  yhhZ  392 aa Hypothetical protein yhhZ n.s. ●○○○○ -0.76 -0.759246260530328
Escherichia coli CFT073  c1883  AAN80343.1  A0A0H2V9J6  652 aa Conserved hypothetical protein n.s. ●○○○○ -0.76 -0.758395231117563
Escherichia coli CFT073  c5242  AAN83664.1  A0A0H2VDV7  frdA  602 aa Fumarate reductase flavoprotein subunit n.s. ●○○○○ -0.76 -0.757367699674965
Escherichia coli CFT073  c3108  AAN81557.1  A0A0H2V9K0  yfiP  249 aa Hypothetical protein yfiP n.s. ●○○○○ -0.76 -0.756238592192622
Escherichia coli CFT073  c0767  AAN79240.1  A0A0H2V585  152 aa Hypothetical protein n.s. ●○○○○ -0.76 -0.755320460134724
Escherichia coli CFT073  c0989  AAN79462.1  A0A0H2V7S8  potH  314 aa Putrescine transport system permease protein potH n.s. ●○○○○ -0.76 -0.755142284843348
Escherichia coli CFT073  c3963  AAN82403.1  P0AFX1  hpf  95 aa Probable sigma(54) modulation protein n.s. ●○○○○ -0.75 -0.752788349417289
Escherichia coli CFT073  c2132  AAN80591.1  Q8FH10  chbG  252 aa Hypothetical protein ydjC n.s. ●○○○○ -0.75 -0.752513671984092
Escherichia coli CFT073  c2978  AAN81428.1  A0A0H2V9B2  eutG  404 aa Ethanolamine utilization protein eutG n.s. ●○○○○ -0.75 -0.751172232471256
Escherichia coli CFT073  c0248  AAN78738.1  P0AEZ8  mltD  452 aa Membrane-bound lytic murein transglycosylase D precursor n.s. ●○○○○ -0.75 -0.751026924091272
Escherichia coli CFT073  c0856  AAN79329.1  Q8FJQ2  bioF  384 aa 8-amino-7-oxononanoate synthase n.s. ●○○○○ -0.75 -0.748558110052671
Escherichia coli CFT073  c5263  AAN83685.1  A0A0H2VG66  vacB  827 aa Ribonuclease R n.s. ●○○○○ -0.75 -0.74803564823578
Escherichia coli CFT073  c0726  AAN79199.1  P0AD66  mrdA  633 aa Penicillin-binding protein 2 n.s. ●○○○○ -0.75 -0.74664450717684
Escherichia coli CFT073  c1170  AAN79638.1  A0A0H2V602  486 aa Hypothetical protein yfjI n.s. ●○○○○ -0.74 -0.742937149561392
Escherichia coli CFT073  c2178  AAN80637.1  A0A0H2V963  ydjJ  347 aa Hypothetical zinc-type alcohol dehydrogenase-like protein ydjJ n.s. ●○○○○ -0.74 -0.741522938890154
Escherichia coli CFT073  c3364  AAN81811.1  A0A0H2VA26  sdaC  429 aa Serine transporter n.s. ●○○○○ -0.74 -0.740490036621823
Escherichia coli CFT073  c3363  AAN81810.1  A0A0H2VBM9  475 aa Hypothetical protein n.s. ●○○○○ -0.74 -0.740490036621823
Escherichia coli CFT073  c1115  AAN79583.1  A0A0H2V5X4  hyaC  235 aa Probable Ni/Fe-hydrogenase 1 B-type cytochrome subunit n.s. ●○○○○ -0.74 -0.74043718129972
Escherichia coli CFT073  c3206  AAN81658.1  A0A0H2V9V0  271 aa Hypothetical protein n.s. ●○○○○ -0.74 -0.739252897987471
Escherichia coli CFT073  c3290  AAN81739.1  A0A0H2V9X6  hypE  336 aa Hydrogenase isoenzymes formation protein hypE n.s. ●○○○○ -0.74 -0.738814839609969
Escherichia coli CFT073  c0487  AAN78965.1  Q8FKE3  ddlA  364 aa D-alanine--D-alanine ligase A n.s. ●○○○○ -0.74 -0.738466507986953
Escherichia coli CFT073  c2173  AAN80632.1  A0A0H2V957  ydjE  475 aa Hypothetical metabolite transport protein ydjE n.s. ●○○○○ -0.74 -0.737969223667877
Escherichia coli CFT073  c2156  AAN80615.1  A0A0H2V7U4  ynjC  519 aa Hypothetical ABC transporter permease protein ynjC n.s. ●○○○○ -0.73 -0.734682083337237
Escherichia coli CFT073  c0688  AAN79163.1  A0A0H2V538  ybdL  386 aa Hypothetical aminotransferase ybdL n.s. ●○○○○ -0.73 -0.732115444870664
Escherichia coli CFT073  c3716  AAN82160.1  A0A0H2VB08  386 aa Hypothetical protein n.s. ●○○○○ -0.73 -0.728640714402385
Escherichia coli CFT073  c3717  AAN82161.1  A0A0H2VDE4  356 aa Hypothetical protein n.s. ●○○○○ -0.73 -0.728640714402385
Escherichia coli CFT073  c2374  AAN80833.1  Q8FGJ7  dgcQ  569 aa Hypothetical protein yedQ n.s. ●○○○○ -0.73 -0.728153626342372
Escherichia coli CFT073  c1003  AAN79476.1  A0A0H2V6H8  ybjU  333 aa Low-specificity L-threonine aldolase n.s. ●○○○○ -0.73 -0.727078076907203
Escherichia coli CFT073  c2299  AAN80758.1  A0A0H2V812  cheR  286 aa Chemotaxis protein methyltransferase n.s. ●○○○○ -0.73 -0.726344697514469
Escherichia coli CFT073  c0830  AAN79303.1  A0A0H2V5C2  aroG  350 aa Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive n.s. ●○○○○ -0.73 -0.725001273043286
Escherichia coli CFT073  c2830  AAN81284.1  A0A0H2V9A1  lrhA  312 aa Probable transcriptional regulator lrhA n.s. ●○○○○ -0.72 -0.724384502596818
Escherichia coli CFT073  c2599  AAN81055.1  A0A0H2V8S9  yegL  219 aa Hypothetical protein yegL n.s. ●○○○○ -0.72 -0.721540280141043
Escherichia coli CFT073  c1026  AAN79498.1  P0ACJ1  lrp  182 aa Leucine-responsive Regulatory protein n.s. ●○○○○ -0.72 -0.719565076041931
Escherichia coli CFT073  c0878  AAN79351.1  Q8FJN6  ybhG  332 aa Hypothetical membrane protein ybhG n.s. ●○○○○ -0.72 -0.718464203123088
Escherichia coli CFT073  c1272  AAN79746.1  A0A0H2V678  290 aa Hypothetical protein yeeP n.s. ●○○○○ -0.72 -0.715791336366945
Escherichia coli CFT073  c3068  AAN81518.1  A0A0H2V9I4  yphD  332 aa Hypothetical ABC transporter permease protein yphD n.s. ●○○○○ -0.72 -0.71571220930057
Escherichia coli CFT073  c3282  AAN81731.1  A0A0H2VA59  hycD  307 aa Formate hydrogenlyase subunit 4 n.s. ●○○○○ -0.71 -0.713798848039347
Escherichia coli CFT073  c1004  AAN79477.1  A0A0H2V5N4  poxB  572 aa Pyruvate dehydrogenase (cytochrome) n.s. ●○○○○ -0.71 -0.710642305707292
Escherichia coli CFT073  c0879  AAN79352.1  A0A0H2V649  ybiH  227 aa Hypothetical transcriptional regulator ybiH n.s. ●○○○○ -0.71 -0.708958445575087
Escherichia coli CFT073  c2591  AAN81047.1  A0A0H2VB17  asmA  617 aa Protein asmA precursor n.s. ●○○○○ -0.71 -0.705090725002609
Escherichia coli CFT073  c2051  AAN80511.1  A0A0H2V9V7  ydhP  389 aa Hypothetical transport protein ydhP n.s. ●○○○○ -0.7 -0.702379376652336
Escherichia coli CFT073  c5144  AAN83566.1  A0A0H2VFY7  499 aa Hypothetical protein n.s. ●○○○○ -0.7 -0.702379376652336
Escherichia coli CFT073  c3122  AAN81572.1  A0A0H2V9U5  aroF  379 aa Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive n.s. ●○○○○ -0.7 -0.702379376652335
Escherichia coli CFT073  c1169  AAN79637.1  A0A0H2V5W7  alpA  82 aa Prophage CP4-57 Regulatory protein alpA n.s. ●○○○○ -0.7 -0.702379376652332
Escherichia coli CFT073  c1150  AAN79618.1  P0ACU3  rutR  221 aa Hypothetical transcriptional regulator ycdC n.s. ●○○○○ -0.7 -0.70237937665233
Escherichia coli CFT073  c4739  AAN83172.1  A0A0H2VCM3  282 aa Conserved hypothetical protein n.s. ●○○○○ -0.7 -0.700772616130425
Escherichia coli CFT073  c0319  AAN78807.1  A0A0H2V4G7  390 aa Putative oligogalacturonide lyase n.s. ●○○○○ -0.7 -0.698532722823392
Escherichia coli CFT073  c1586  AAN80054.1  A0A0H2V6S3  216 aa Hypothetical protein n.s. ●○○○○ -0.7 -0.697457613736633
Escherichia coli CFT073  c0598  AAN79076.1  A0A0H2V5J8  ybaL  558 aa Hypothetical protein ybaL n.s. ●○○○○ -0.7 -0.696122126935752
Escherichia coli CFT073  c4334  AAN82770.1  A0A0H2VBU7  yhjE  440 aa Hypothetical metabolite transport protein yhjE n.s. ●○○○○ -0.7 -0.695781098741962
Escherichia coli CFT073  c3564  AAN82012.1  A0A0H2VAG8  490 aa Hypothetical protein n.s. ●○○○○ -0.69 -0.692372385044211
Escherichia coli CFT073  c5431  AAN83851.1  A0A0H2VE93  423 aa Hypothetical protein n.s. ●○○○○ -0.69 -0.688887345062194
Escherichia coli CFT073  c0491  AAN78969.1  P0AFM5  psiF  112 aa Phosphate starvation-inducible protein psiF precursor n.s. ●○○○○ -0.69 -0.688641288272911
Escherichia coli CFT073  c3210  AAN81662.1  A0A0H2VA09  gabT  428 aa 4-aminobutyrate aminotransferase n.s. ●○○○○ -0.69 -0.687462434183411
Escherichia coli CFT073  c3310  AAN81759.1  Q8FEJ8  pcm  208 aa Protein-L-isoaspartate O-methyltransferase n.s. ●○○○○ -0.69 -0.686294550181575
Escherichia coli CFT073  c0780  AAN79253.1  A0A0H2V7C4  kdpD  895 aa Sensor protein kdpD n.s. ●○○○○ -0.68 -0.683814462438645
Escherichia coli CFT073  c2696  AAN81152.1  Q8FFT8  rihB  313 aa Hypothetical protein yeiK n.s. ●○○○○ -0.68 -0.681968623549323
Escherichia coli CFT073  c2923  AAN81373.1  A0A0H2V9G3  ypdE  345 aa Hypothetical protein ypdE n.s. ●○○○○ -0.68 -0.680384958967424
Escherichia coli CFT073  c2430  AAN80889.1  A0A0H2V9Q1  366 aa Hypothetical protein n.s. ●○○○○ -0.68 -0.680089686686722
Escherichia coli CFT073  c1002  AAN79475.1  A0A0H2V5Q7  ybjT  501 aa Hypothetical protein ybjT n.s. ●○○○○ -0.68 -0.67775407666419
Escherichia coli CFT073  c2769  AAN81223.1  A0A0H2V8Z4  yfaQ  549 aa Hypothetical protein yfaQ precursor n.s. ●○○○○ -0.68 -0.675314279763566
Escherichia coli CFT073  c2781  AAN81235.1  A0A0H2V903  glpT  452 aa Glycerol-3-phosphate transporter n.s. ●○○○○ -0.67 -0.674536208287853
Escherichia coli CFT073  c3955  AAN82395.1  P63387  mlaF  269 aa Hypothetical ABC transporter ATP-binding protein yrbF n.s. ●○○○○ -0.67 -0.672224478229769
Escherichia coli CFT073  c0542  AAN79020.1  P0ABI9  cyoB  663 aa Ubiquinol oxidase polypeptide I n.s. ●○○○○ -0.67 -0.671715289115052
Escherichia coli CFT073  c0743  AAN79216.1  P0AE79  corC  292 aa Magnesium and cobalt efflux protein corC n.s. ●○○○○ -0.67 -0.670266458636774
Escherichia coli CFT073  c3702  AAN82148.1  A0A0H2VAU1  137 aa Hypothetical protein n.s. ●○○○○ -0.67 -0.669193632327103
Escherichia coli CFT073  c0530  AAN79008.1  A0A0H2V5H6  yajO  324 aa Hypothetical oxidoreductase yajO n.s. ●○○○○ -0.66 -0.664817704558469
Escherichia coli CFT073  c1418  AAN79887.1  A0A0H2V6F4  72 aa Hypothetical protein n.s. ●○○○○ -0.66 -0.66395494943779
Escherichia coli CFT073  c2691  AAN81147.1  A0A0H2VB81  lysP  489 aa Lysine-specific permease n.s. ●○○○○ -0.66 -0.663498270011448
Escherichia coli CFT073  c1274  AAN79748.1  A0A0H2V650  840 aa Hypothetical protein yeeR n.s. ●○○○○ -0.66 -0.662545845812259
Escherichia coli CFT073  c3554  AAN82002.1  A0A0H2VAG0  67 aa Hypothetical protein n.s. ●○○○○ -0.66 -0.661659201488251
Escherichia coli CFT073  c0906  AAN79379.1  P0A9U4  ybiT  530 aa Hypothetical ABC transporter ATP-binding protein ybiT n.s. ●○○○○ -0.66 -0.661659201488241
Escherichia coli CFT073  c3393  AAN81838.1  A0A0H2VBP9  824 aa Hypothetical protein n.s. ●○○○○ -0.66 -0.660732186265482
Escherichia coli CFT073  c0194  AAN78688.1  Q8CWD2  btuF  266 aa Vitamin B12 transport protein btuF precursor n.s. ●○○○○ -0.66 -0.660398443531483
Escherichia coli CFT073  c0791  AAN79264.1  A0A0H2V5Z3  ybgK  310 aa Hypothetical protein ybgK n.s. ●○○○○ -0.66 -0.660261175722116
Escherichia coli CFT073  c3237  AAN81689.1  P0ACS0  mprA  176 aa Transcriptional repressor mprA n.s. ●○○○○ -0.66 -0.657715698044083
Escherichia coli CFT073  c1948  AAN80405.1  A0A0H2V7D8  yneI  470 aa Aldehyde-dehydrogenase like protein yneI n.s. ●○○○○ -0.66 -0.657312257553411
Escherichia coli CFT073  c0957  AAN79430.1  A0A0H2V5M2  170 aa Fels-2 prophage: probable prophage lysozyme n.s. ●○○○○ -0.66 -0.656479067643147
Escherichia coli CFT073  c3076  AAN81525.1  P0A9Z2  glnB  112 aa Nitrogen Regulatory protein P-II 1 n.s. ●○○○○ -0.66 -0.656479067643147
Escherichia coli CFT073  c2663  AAN81119.1  A0A0H2V8S7  bglX  765 aa Periplasmic beta-glucosidase precursor n.s. ●○○○○ -0.66 -0.656479067643147
Escherichia coli CFT073  c1006  AAN79479.1  Q8FJE0  hcp  552 aa Prismane protein homolog n.s. ●○○○○ -0.65 -0.654925484468567
Escherichia coli CFT073  c1423  AAN79892.1  A0A0H2V6F7  349 aa Hypothetical protein ydfU n.s. ●○○○○ -0.65 -0.654925484468559
Escherichia coli CFT073  c4042  AAN82480.1  Q8FD18  aroE  272 aa Shikimate 5-dehydrogenase n.s. ●○○○○ -0.65 -0.654835114031592
Escherichia coli CFT073  c3450  AAN81895.1  P65808  ygeY  403 aa Hypothetical protein ygeY n.s. ●○○○○ -0.65 -0.65060828177131
Escherichia coli CFT073  c3300  AAN81749.1  A0A0H2VBI9  ygbM  258 aa Hypothetical protein ygbM n.s. ●○○○○ -0.65 -0.649698469534601
Escherichia coli CFT073  c0880  AAN79353.1  A0A0H2V5F2  rhlE  453 aa Putative ATP-dependent RNA helicase rhlE n.s. ●○○○○ -0.65 -0.649202603689739
Escherichia coli CFT073  c2467  AAN80926.1  A0A0H2V8E7  289 aa Putative 3-hydroxyacyl-CoA dehydrogenase n.s. ●○○○○ -0.65 -0.649093568947772
Escherichia coli CFT073  c2468  AAN80927.1  A0A0H2V8M8  869 aa Putative polyketide synthase n.s. ●○○○○ -0.65 -0.648676051675692
Escherichia coli CFT073  c3179  AAN81631.1  A0A0H2V9S4  ydfP  165 aa Hypothetical protein ydfP precursor n.s. ●○○○○ -0.65 -0.648259245611719
Escherichia coli CFT073  c2768  AAN81222.1  A0A0H2VAG6  yfaP  258 aa Hypothetical protein yfaP precursor n.s. ●○○○○ -0.65 -0.64792111310883
Escherichia coli CFT073  c1686  AAN80153.1  A0A0H2V6X0  narH  512 aa Respiratory nitrate reductase 1 beta chain n.s. ●○○○○ -0.65 -0.646795940778449
Escherichia coli CFT073  c4466  AAN82902.1  P0A7E4  pyrE  218 aa Orotate phosphoribosyltransferase n.s. ●○○○○ -0.65 -0.645847992535158
Escherichia coli CFT073  c0456  AAN78935.1  A0A0H2V4N7  codA  432 aa Cytosine deaminase n.s. ●○○○○ -0.65 -0.645715248044592
Escherichia coli CFT073  c3434  AAN81879.1  A0A0H2VBS6  galR  343 aa Galactose operon repressor n.s. ●○○○○ -0.64 -0.644912581163884
Escherichia coli CFT073  c1114  AAN79582.1  A0A0H2V5S8  hyaB  597 aa Hydrogenase-1 large chain n.s. ●○○○○ -0.64 -0.642181379335639
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