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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli CFT073  c0445  AAN78924.1  A0A0H2V4N0  yahJ  460 aa Hypothetical protein yahJ n.s. ●○○○○ -0.64 -0.642111576287679
Escherichia coli CFT073  c3638  AAN82086.1  Q8FDU8  nanK2  291 aa Hypothetical protein yhcI n.s. ●○○○○ -0.64 -0.641788385929057
Escherichia coli CFT073  c2762  AAN81216.1  A0A0H2V920  atoS  612 aa Sensor protein atoS n.s. ●○○○○ -0.64 -0.641449543649555
Escherichia coli CFT073  c4448  AAN82884.1  A0A0H2VDM0  waaL  417 aa Lipid A-core, surface polymer ligase n.s. ●○○○○ -0.64 -0.639637993589526
Escherichia coli CFT073  c0505  AAN78983.1  A0A0H2V4T3  sbcC  1047 aa Exonuclease sbcC n.s. ●○○○○ -0.64 -0.639201197805754
Escherichia coli CFT073  c3905  AAN82346.1  A0A0H2VCS2  yraQ  346 aa Hypothetical protein yraQ n.s. ●○○○○ -0.64 -0.637642943811073
Escherichia coli CFT073  c3256  AAN81707.1  A0A0H2VCB8  srlA  187 aa PTS system, glucitol/sorbitol-specific IIC2 component n.s. ●○○○○ -0.63 -0.634509153394218
Escherichia coli CFT073  c0386  AAN78867.1  Q8FKM5  frsA  414 aa Hypothetical protein yafA n.s. ●○○○○ -0.63 -0.633480753568114
Escherichia coli CFT073  c5005  AAN83431.1  Q8FB37  malK  401 aa Maltose/maltodextrin transport ATP-binding protein malK n.s. ●○○○○ -0.63 -0.632923738590272
Escherichia coli CFT073  c3224  AAN81676.1  A0A0H2V9S7  444 aa Conserved hypothetical protein n.s. ●○○○○ -0.62 -0.618459431047654
Escherichia coli CFT073  c0582  AAN79060.1  P0ACT0  acrR  215 aa Potential acrAB operon repressor n.s. ●○○○○ -0.62 -0.618087823416405
Escherichia coli CFT073  c3263  AAN81714.1  Q8FEN6  norR  529 aa Hypothetical sigma-54-dependent transcriptional regulator ygaA n.s. ●○○○○ -0.62 -0.618044643887787
Escherichia coli CFT073  c2581  AAN81036.1  A0A0H2VB09  wcaE  248 aa Putative colanic acid biosynthesis glycosyl transferase wcaE n.s. ●○○○○ -0.62 -0.616002929904797
Escherichia coli CFT073  c0757  AAN79230.1  A0A0H2V5W4  426 aa Hypothetical protein n.s. ●○○○○ -0.62 -0.615895420160529
Escherichia coli CFT073  c5249  AAN83671.1  P0A785  orn  220 aa Oligoribonuclease n.s. ●○○○○ -0.61 -0.612569867009821
Escherichia coli CFT073  c2133  AAN80592.1  A0A0H2V7R2  celF  468 aa 6-phospho-beta-glucosidase n.s. ●○○○○ -0.61 -0.61256986700981
Escherichia coli CFT073  c2909  AAN81359.1  A0A0H2V970  564 aa Probable oxalyl-CoA decarboxylase n.s. ●○○○○ -0.61 -0.611445441124331
Escherichia coli CFT073  c1716  AAN80183.1  P0AB56  yciI  130 aa Protein yciI n.s. ●○○○○ -0.61 -0.611269948320602
Escherichia coli CFT073  c1812  AAN80276.1  A0A0H2V732  132 aa Hypothetical protein n.s. ●○○○○ -0.61 -0.611159920881798
Escherichia coli CFT073  c1811  AAN80275.1  A0A0H2V8B6  102 aa Hypothetical protein n.s. ●○○○○ -0.61 -0.611159920881798
Escherichia coli CFT073  c4342  AAN82778.1  A0A0H2VBS4  yhjL  1157 aa Cellulose synthase operon protein C n.s. ●○○○○ -0.61 -0.610762084672891
Escherichia coli CFT073  c2958  AAN81408.1  A0A0H2V9A0  cysU  277 aa Sulfate transport system permease protein cysT n.s. ●○○○○ -0.61 -0.610270039806582
Escherichia coli CFT073  c2720  AAN81174.1  P0AA44  rsuA  263 aa Ribosomal small subunit pseudouridine synthase A n.s. ●○○○○ -0.61 -0.60885257160712
Escherichia coli CFT073  c0561  AAN79039.1  A0A0H2V4U9  ybaE  571 aa Hypothetical protein ybaE n.s. ●○○○○ -0.61 -0.606524950205879
Escherichia coli CFT073  c0325  AAN78813.1  A0A0H2V6C6  326 aa Hypothetical protein n.s. ●○○○○ -0.61 -0.606040817687983
Escherichia coli CFT073  c1900  AAN80360.1  A0A0H2V8K3  narZ  1287 aa Respiratory nitrate reductase 2 alpha chain n.s. ●○○○○ -0.61 -0.605670781834235
Escherichia coli CFT073  c0691  AAN79166.1  A0A0H2V543  ybdO  312 aa Hypothetical transcriptional regulator ybdO n.s. ●○○○○ -0.61 -0.60516401906074
Escherichia coli CFT073  c5425  AAN83845.1  A0A0H2VE89  810 aa Putative restriction modification enzyme R subunit n.s. ●○○○○ -0.6 -0.604038014294953
Escherichia coli CFT073  c2470  AAN80929.1  A0A0H2V8I0  1875 aa Putative peptide/polyketide synthase n.s. ●○○○○ -0.6 -0.603677725959566
Escherichia coli CFT073  c3367  AAN81814.1  A0A0H2VCI4  fucO  383 aa Lactaldehyde reductase n.s. ●○○○○ -0.6 -0.603580010746988
Escherichia coli CFT073  c3720  AAN82164.1  A0A0H2VAS6  yghQ  449 aa Hypothetical protein yghQ n.s. ●○○○○ -0.6 -0.603580010746988
Escherichia coli CFT073  c3031  AAN81481.1  A0A0H2VAY3  735 aa SinH homolog n.s. ●○○○○ -0.6 -0.602983032099356
Escherichia coli CFT073  c2547  AAN81002.1  Q8FG52  hisD  437 aa Histidinol dehydrogenase n.s. ●○○○○ -0.6 -0.599008036597314
Escherichia coli CFT073  c2988  AAN81438.1  A0A0H2V9J3  759 aa NADP-dependent malic enzyme n.s. ●○○○○ -0.6 -0.598430663981162
Escherichia coli CFT073  c3508  AAN81956.1  A0A0H2VAB3  235 aa Hypothetical protein n.s. ●○○○○ -0.6 -0.597162506967535
Escherichia coli CFT073  c4036  AAN82476.1  A0A0H2VB88  yhdY  368 aa Hypothetical amino-acid ABC transporter permease protein yhdY n.s. ●○○○○ -0.6 -0.595945177205325
Escherichia coli CFT073  c2995  AAN81445.1  A0A0H2V9J8  yffG  659 aa AegA protein n.s. ●○○○○ -0.6 -0.595367396013621
Escherichia coli CFT073  c3020  AAN81470.1  P0AFL7  ppx  513 aa Exopolyphosphatase n.s. ●○○○○ -0.6 -0.595051108126461
Escherichia coli CFT073  c2743  AAN81197.1  A0A0H2VBB4  napH  287 aa Ferredoxin-type protein napH n.s. ●○○○○ -0.59 -0.593882930347777
Escherichia coli CFT073  c0685  AAN79160.1  A0A0H2V539  cstA  701 aa Carbon starvation protein A n.s. ●○○○○ -0.59 -0.593731710261482
Escherichia coli CFT073  c2791  AAN81245.1  A0A0H2VBF4  400 aa CinA-like protein n.s. ●○○○○ -0.59 -0.593547935523657
Escherichia coli CFT073  c4037  AAN82477.1  A0A0H2VBN0  yhdZ  252 aa Hypothetical amino-acid ABC transporter ATP-binding protein yhdZ n.s. ●○○○○ -0.59 -0.592118066080911
Escherichia coli CFT073  c3398  AAN81843.1  A0A0H2VBQ4  1112 aa Hypothetical protein n.s. ●○○○○ -0.59 -0.590780446285191
Escherichia coli CFT073  c0776  AAN79249.1  P0AAF2  potE  439 aa Putrescine-ornithine antiporter n.s. ●○○○○ -0.58 -0.584521727570968
Escherichia coli CFT073  c2593  AAN81049.1  P0A8F5  udk  234 aa Uridine kinase n.s. ●○○○○ -0.58 -0.584202441249597
Escherichia coli CFT073  c1117  AAN79585.1  A0A0H2V5W8  hyaE  132 aa Hydrogenase-1 operon protein hyaE n.s. ●○○○○ -0.58 -0.583855137025937
Escherichia coli CFT073  c0602  AAN79080.1  A0A0H2V4Y0  ybaP  264 aa Hypothetical protein ybaP n.s. ●○○○○ -0.58 -0.583732495870062
Escherichia coli CFT073  c0634  AAN79111.1  A0A0H2V501  ylbF  302 aa Hypothetical protein ylbF n.s. ●○○○○ -0.58 -0.583642642242808
Escherichia coli CFT073  c1194  AAN79656.1  A0A0H2V6U8  540 aa Putative enzyme n.s. ●○○○○ -0.58 -0.5834759577333
Escherichia coli CFT073  c0785  AAN79258.1  A0A0H2V5Y7  ybfA  68 aa Hypothetical protein ybfA precursor n.s. ●○○○○ -0.58 -0.579951637886372
Escherichia coli CFT073  c0734  AAN79207.1  P0AAU0  ybeL  160 aa Hypothetical protein ybeL n.s. ●○○○○ -0.58 -0.578706106366297
Escherichia coli CFT073  c0261  AAN78751.1  A0A0H2V4B7  377 aa Hypothetical protein n.s. ●○○○○ -0.58 -0.578417834335951
Escherichia coli CFT073  c0459  AAN78938.1  Q8FKG6  lacZ  1024 aa Beta-galactosidase n.s. ●○○○○ -0.58 -0.577949313845235
Escherichia coli CFT073  c0887  AAN79360.1  A0A0H2V5F7  121 aa Hypothetical protein n.s. ●○○○○ -0.58 -0.577677706540191
Escherichia coli CFT073  c0924  AAN79397.1  A0A0H2V6B0  dacC  407 aa Penicillin-binding protein 6 precursor n.s. ●○○○○ -0.58 -0.577646883790724
Escherichia coli CFT073  c0635  AAN79112.1  Q8FK51  arcC  297 aa Carbamate kinase n.s. ●○○○○ -0.58 -0.576478497926808
Escherichia coli CFT073  c0630  AAN79107.1  A0A0H2V5M5  ylbB  417 aa Allantoate amidohydrolase n.s. ●○○○○ -0.58 -0.576329501152146
Escherichia coli CFT073  c2906  AAN81356.1  A0A0H2V999  evgS  1197 aa Sensor protein evgS precursor n.s. ●○○○○ -0.57 -0.574069641512332
Escherichia coli CFT073  c2697  AAN81153.1  A0A0H2VAC5  yeiL  232 aa Regulatory protein nsr n.s. ●○○○○ -0.57 -0.572802490555443
Escherichia coli CFT073  c0794  AAN79267.1  A0A0H2V596  abrB  363 aa AbrB protein n.s. ●○○○○ -0.57 -0.572743348449563
Escherichia coli CFT073  c0048  AAN78546.1  P60585  caiA  380 aa Crotonobetainyl-CoA dehydrogenase n.s. ●○○○○ -0.57 -0.57083148566547
Escherichia coli CFT073  c1634  AAN80099.1  Q8FI24  nhaB  531 aa Na(+)/H(+) antiporter 2 n.s. ●○○○○ -0.57 -0.569852776827685
Escherichia coli CFT073  c3382  AAN81827.1  A0A0H2VA52  ygdK  147 aa Hypothetical protein ygdK n.s. ●○○○○ -0.57 -0.569405225864964
Escherichia coli CFT073  c2471  AAN80930.1  A0A0H2V9T5  244 aa Hypothetical protein n.s. ●○○○○ -0.57 -0.569018288345157
Escherichia coli CFT073  c0401  AAN78882.1  Q8FKL3  ecpD  547 aa Hypothetical protein yagW n.s. ●○○○○ -0.57 -0.568968992183678
Escherichia coli CFT073  c3348  AAN81796.1  Q8FEG6  rlmD  433 aa 23S rRNA (Uracil-5-)-methyltransferase rumA n.s. ●○○○○ -0.57 -0.567177068347626
Escherichia coli CFT073  c2476  AAN80935.1  A0A0H2V9U4  erfK  311 aa Protein erfK/srfK precursor n.s. ●○○○○ -0.56 -0.564508347288339
Escherichia coli CFT073  c1241  AAN79698.1  P62610  focC  231 aa F1C periplasmic chaperone n.s. ●○○○○ -0.56 -0.562071355566692
Escherichia coli CFT073  c2940  AAN81390.1  A0A0H2V990  xapA  277 aa Xanthosine phosphorylase n.s. ●○○○○ -0.56 -0.561578296203463
Escherichia coli CFT073  c0958  AAN79431.1  A0A0H2V6E4  139 aa Putative membrane protein n.s. ●○○○○ -0.56 -0.560884873873482
Escherichia coli CFT073  c3385  AAN81830.1  A0A0H2VAC2  173 aa Hypothetical protein n.s. ●○○○○ -0.56 -0.560884873873482
Escherichia coli CFT073  c2540  AAN80994.1  A0A0H2V8N9  yeeF  454 aa Hypothetical transport protein yeeF n.s. ●○○○○ -0.56 -0.557962626335894
Escherichia coli CFT073  c1550  AAN80019.1  A0A0H2V7R5  233 aa Putative replication protein P of bacteriophage n.s. ●○○○○ -0.56 -0.556528219065349
Escherichia coli CFT073  c2740  AAN81194.1  A0A0H2VAE9  197 aa Hypothetical protein n.s. ●○○○○ -0.56 -0.556387541884018
Escherichia coli CFT073  c2739  AAN81193.1  P0ABL6  napC  200 aa Cytochrome c-type protein napC n.s. ●○○○○ -0.56 -0.556387541884018
Escherichia coli CFT073  c2518  AAN80973.1  A0A0H2V4E2  721 aa TonB dependent receptor n.s. ●○○○○ -0.56 -0.555370775465725
Escherichia coli CFT073  c0711  AAN79184.1  P0AEF5  dpiA  226 aa Transcriptional Regulatory protein dpiA n.s. ●○○○○ -0.55 -0.552118639951435
Escherichia coli CFT073  c3749  AAN82193.1  Q8FDK9  ygiQ  739 aa Conserved hypothetical protein n.s. ●○○○○ -0.55 -0.550650690189601
Escherichia coli CFT073  c3494  AAN81942.1  P0A9T1  serA  410 aa D-3-phosphoglycerate dehydrogenase n.s. ●○○○○ -0.55 -0.550253343625258
Escherichia coli CFT073  c3456  AAN81901.1  A0A0H2VA84  ygfK  1032 aa Hypothetical protein ygfK n.s. ●○○○○ -0.55 -0.549515913073683
Escherichia coli CFT073  c2304  AAN80763.1  A0A0H2V9E2  motB  308 aa Chemotaxis motB protein n.s. ●○○○○ -0.55 -0.546461794497452
Escherichia coli CFT073  c1118  AAN79586.1  A0A0H2V6Q0  hyaF  285 aa Hydrogenase-1 operon protein hyaF n.s. ●○○○○ -0.55 -0.546246267476276
Escherichia coli CFT073  c0190  AAN78684.1  Q8FL15  clcA  473 aa Voltage-gated ClC-type chloride channel eriC n.s. ●○○○○ -0.55 -0.545226083952378
Escherichia coli CFT073  c4158  AAN82596.1  A0A0H2VE44  damX  428 aa DamX protein n.s. ●○○○○ -0.54 -0.544720724627926
Escherichia coli CFT073  c3039  AAN81489.1  Q8FF55  rlmN  384 aa Hypothetical protein yfgB n.s. ●○○○○ -0.54 -0.544033090793659
Escherichia coli CFT073  c0580  AAN79058.1  A0A0H2V4W9  acrB  1049 aa Acriflavine resistance protein B n.s. ●○○○○ -0.54 -0.537101559200064
Escherichia coli CFT073  c2849  AAN81303.1  P0AEU4  hisM  238 aa Histidine transport system permease protein hisM n.s. ●○○○○ -0.54 -0.536053093940273
Escherichia coli CFT073  c0432  AAN78913.1  Q8FKI8  betB  491 aa Betaine aldehyde dehydrogenase n.s. ●○○○○ -0.53 -0.533794607726313
Escherichia coli CFT073  c3042  AAN81492.1  A0A0H2VAY7  pbpC  770 aa Penicillin-binding protein 1C n.s. ●○○○○ -0.53 -0.532226102833183
Escherichia coli CFT073  c3067  AAN81517.1  A0A0H2VB26  yphC  364 aa Hypothetical zinc-type alcohol dehydrogenase-like protein yphC n.s. ●○○○○ -0.53 -0.531850265716259
Escherichia coli CFT073  c0604  AAN79082.1  A0A0H2V5K6  ybaR  834 aa Copper-transporting P-type ATPase n.s. ●○○○○ -0.53 -0.529986081823383
Escherichia coli CFT073  c3319  AAN81768.1  Q8FEJ0  cysD  302 aa Sulfate adenylyltransferase subunit 2 n.s. ●○○○○ -0.53 -0.529359064440048
Escherichia coli CFT073  c0584  AAN79062.1  A0A0H2V4W8  aefA  1120 aa Potassium efflux system kefA n.s. ●○○○○ -0.53 -0.528571854348385
Escherichia coli CFT073  c0345  AAN78830.1  A0A0H2V540  3216 aa Putative member of ShlA/HecA/FhaA exoprotein family n.s. ●○○○○ -0.53 -0.528119012231068
Escherichia coli CFT073  c2942  AAN81392.1  A0A0H2VBQ0  yfeR  308 aa Hypothetical transcriptional regulator yfeR n.s. ●○○○○ -0.53 -0.527774685569494
Escherichia coli CFT073  c1256  AAN79730.1  A0A0H2V827  169 aa Hypothetical protein n.s. ●○○○○ -0.53 -0.525040699717581
Escherichia coli CFT073  c0450  AAN78929.1  A0A0H2V4N4  prpR  528 aa Propionate catabolism operon Regulatory protein n.s. ●○○○○ -0.52 -0.524653098553979
Escherichia coli CFT073  c0749  AAN79222.1  A0A0H2V570  asnB  632 aa Asparagine synthetase B (glutamine-hydrolyzing) n.s. ●○○○○ -0.52 -0.523453093970414
Escherichia coli CFT073  c2526  AAN80980.1  A0A0H2VAX2  273 aa Hypothetical protein yafZ n.s. ●○○○○ -0.52 -0.522741162247987
Escherichia coli CFT073  c0684  AAN79159.1  P0A8Y9  entH  137 aa Hypothetical protein ybdB n.s. ●○○○○ -0.52 -0.521490174904191
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