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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1343  WP_002869327.1  A1W0W0  tsaD  335 aa tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD n.s. ●○○○○ -0.58 -0.57918204432
Serratia marcescens Strain UMH9  BVG96_16630  ASL99149.1  264 aa aspartate dehydrogenase n.s. ●○○○○ -0.58 -0.57912244188691
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0999  WP_002856444.1  A0A0H3P9E4  pepD  422 aa M20/M25/M40 family metallo-hydrolase n.s. ●○○○○ -0.58 -0.579092711867
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0373  WP_002868918.1  A1VY70  trpA  249 aa tryptophan synthase subunit alpha n.s. ●○○○○ -0.58 -0.578730462312
Escherichia coli CFT073  c0734  AAN79207.1  P0AAU0  ybeL  160 aa Hypothetical protein ybeL n.s. ●○○○○ -0.58 -0.578706106366297
Mycobacterium avium subsp. paratuberculosis K10  MAP_2942c  AAS05259.1  Q73VR9  mpt53  172 aa Mpt53 n.s. ●○○○○ -0.58 -0.578464301255411
Mycobacterium avium subsp. paratuberculosis K10  MAP_2621c  AAS04938.1  Q73WN9  mutT2  130 aa MutT2 n.s. ●○○○○ -0.58 -0.578425461226704
Escherichia coli CFT073  c0261  AAN78751.1  A0A0H2V4B7  377 aa Hypothetical protein n.s. ●○○○○ -0.58 -0.578417834335951
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1729  CBW17824.1  A0A0H3NHI3  cvrA  577 aa Cell volume regulation protein A. Cell volume regulation protein A homolog. n.s. ●○○○○ -0.58 -0.57833344412201
Vibrio parahaemolyticus RIMD 2210633  VPA_0658  BAC62001.1  Q87IE8  311 aa iron(III) ABC transporter, permease protein n.s. ●○○○○ -0.58 -0.578067062473293
Serratia marcescens Strain UMH9  BVG96_14430  ASL98750.1  216 aa DUF421 domain-containing protein n.s. ●○○○○ -0.58 -0.577998823405202
Escherichia coli CFT073  c0459  AAN78938.1  Q8FKG6  lacZ  1024 aa Beta-galactosidase n.s. ●○○○○ -0.58 -0.577949313845235
Serratia marcescens Strain UMH9  BVG96_08775  ASL97703.1  297 aa LysR family transcriptional regulator n.s. ●○○○○ -0.58 -0.5778944247742
Escherichia coli CFT073  c0887  AAN79360.1  A0A0H2V5F7  121 aa Hypothetical protein n.s. ●○○○○ -0.58 -0.577677706540191
Escherichia coli CFT073  c0924  AAN79397.1  A0A0H2V6B0  dacC  407 aa Penicillin-binding protein 6 precursor n.s. ●○○○○ -0.58 -0.577646883790724
Mycobacterium avium subsp. paratuberculosis K10  MAP_2313c  AAS04630.1  Q73XJ6  accA1  671 aa AccA1 n.s. ●○○○○ -0.58 -0.577613512944599
Vibrio parahaemolyticus RIMD 2210633  VP_1462  BAC59725.1  Q87PN9  477 aa putative polysaccharide export protein n.s. ●○○○○ -0.58 -0.577540007953495
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4240  WP_000580402.1  E8XKC5  cpxA  457 aa envelope stress sensor histidine kinase CpxA n.s. ●○○○○ -0.58 -0.577229500204947
Mycobacterium avium subsp. paratuberculosis K10  MAP_3218c  AAS05766.1  Q73UZ8  moxR3  325 aa MoxR3 n.s. ●○○○○ -0.58 -0.577119995158391
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3085  CBW19184.1  A0A0H3NHT0  mutY  350 aa A/G-specific adenine glycosylase n.s. ●○○○○ -0.58 -0.576899044345933
Escherichia coli O157:H7 str. EDL933  Z1089  AAG55238.1  493 aa putative sulfatase n.s. ●○○○○ -0.58 -0.576605289845546
Vibrio parahaemolyticus RIMD 2210633  VPA_0887  BAC62230.1  Q87HR9  129 aa hypothetical protein n.s. ●○○○○ -0.58 -0.576525503203363
Escherichia coli CFT073  c0635  AAN79112.1  Q8FK51  arcC  297 aa Carbamate kinase n.s. ●○○○○ -0.58 -0.576478497926808
Vibrio parahaemolyticus RIMD 2210633  VPA_0621  BAC61964.1  Q87II5  497 aa methylmalonate-semialdehyde dehydrogenase n.s. ●○○○○ -0.58 -0.576478168804034
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0516  WP_000186618.1  E8X882  ybak  159 aa Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK n.s. ●○○○○ -0.58 -0.576464255167385
Streptococcus pyogenes M1 5448  SP5448_04405  WP_009881060.1  276 aa DnaD domain protein n.s. ●○○○○ -0.58 -0.576401655259066
Vibrio parahaemolyticus RIMD 2210633  VPA_1470  BAC62813.1  Q87G47  308 aa conserved hypothetical protein n.s. ●○○○○ -0.58 -0.576397658859606
Escherichia coli CFT073  c0630  AAN79107.1  A0A0H2V5M5  ylbB  417 aa Allantoate amidohydrolase n.s. ●○○○○ -0.58 -0.576329501152146
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1183  WP_000846319.1  E8XEV5  rluC  319 aa 23S rRNA pseudouridine(955/2504/2580) synthase RluC n.s. ●○○○○ -0.58 -0.576170800804044
Mycobacterium avium subsp. paratuberculosis K10  MAP_3441  AAS05991.1  Q73UC7  sdhC  151 aa SdhC n.s. ●○○○○ -0.58 -0.576092977248554
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0318  CBW16419.1  A0A0H3N804  proA  416 aa gamma-glutamyl phosphate reductase n.s. ●○○○○ -0.58 -0.576076364274388
Streptococcus pyogenes M1 5448  SP5448_00990  WP_002987925.1  176 aa nuclease n.s. ●○○○○ -0.58 -0.57601712065984
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3210  CBW19308.1  A0A0H3NS59  yhaN  436 aa conserved hypothetical protein n.s. ●○○○○ -0.58 -0.575604002409021
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0283  WP_000449778.1  E8XIT6  879 aa type VI secretion system ATPase TssH n.s. ●○○○○ -0.58 -0.575412733734574
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0932  WP_000934063.1  E8XCQ3  clpA  758 aa ATP-dependent Clp protease ATP-binding subunit ClpA n.s. ●○○○○ -0.58 -0.575071637438599
Vibrio parahaemolyticus RIMD 2210633  VP_2662  BAC60925.1  Q87LF0  162 aa putative ABC superfamily transport protein n.s. ●○○○○ -0.57 -0.574836674930731
Streptococcus pyogenes M1 5448  SP5448_00960  WP_002987913.1  575 aa ABC transporter permease subunit n.s. ●○○○○ -0.57 -0.574767383212356
Streptococcus pyogenes M1 5448  SP5448_04060  WP_010922411.1  792 aa internalin A n.s. ●○○○○ -0.57 -0.57467124956255
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0813  CBW16911.1  A0A0H3NEN3  ybiT  530 aa ABC transporter ATP-binding protein n.s. ●○○○○ -0.57 -0.574546604537084
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1317  CBW17413.1  A0A0H3NAX3  ttrA  1020 aa tetrathionate reductase subunit A n.s. ●○○○○ -0.57 -0.574529095400768
Escherichia coli M12  CO715_12865  ATI06522.1  495 aa transcription termination protein NusA n.s. ●○○○○ -0.57 -0.574311965998399
Escherichia coli M12  CO715_11860  ATI06340.1  85 aa hypothetical protein n.s. ●○○○○ -0.57 -0.574311965998399
Vibrio parahaemolyticus RIMD 2210633  VP_0179  BAC58442.1  Q87T91  lpxL  316 aa lipid A biosynthesis lauroyl acyltransferase n.s. ●○○○○ -0.57 -0.574078505233304
Escherichia coli CFT073  c2906  AAN81356.1  A0A0H2V999  evgS  1197 aa Sensor protein evgS precursor n.s. ●○○○○ -0.57 -0.574069641512332
Mycobacterium avium subsp. paratuberculosis K10  MAP_3244  AAS05792.1  Q73UX2  399 aa hypothetical protein n.s. ●○○○○ -0.57 -0.573632509106435
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0704  CBW16802.1  A0A0H3N934  256 aa O-antigen export system, permease protein n.s. ●○○○○ -0.57 -0.573582063034237
Serratia marcescens Strain UMH9  BVG96_03560  ASL96730.1  432 aa citrate transporter n.s. ●○○○○ -0.57 -0.573464081912272
Streptococcus pyogenes M1 5448  SP5448_04205  WP_002992851.1  149 aa DUF3284 domain-containing protein n.s. ●○○○○ -0.57 -0.573421512115065
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3005  CBW19104.1  A0A0H3NHJ0  STM3026  358 aa probable fimbrial membrane protein n.s. ●○○○○ -0.57 -0.573143496870835
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3105  CBW19204.1  A0A0H3NHV0  161 aa conserved hypothetical protein n.s. ●○○○○ -0.57 -0.572919706243519
Vibrio parahaemolyticus RIMD 2210633  VPA_1020  BAC62363.1  Q87HE5  174 aa hypothetical protein n.s. ●○○○○ -0.57 -0.572890129486058
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1715  CBW17810.1  A0A0H3NM03  597 aa hydrogenase-1 large chain (nifE hydrogenase) n.s. ●○○○○ -0.57 -0.572835572856953
Escherichia coli CFT073  c2697  AAN81153.1  A0A0H2VAC5  yeiL  232 aa Regulatory protein nsr n.s. ●○○○○ -0.57 -0.572802490555443
Escherichia coli CFT073  c0794  AAN79267.1  A0A0H2V596  abrB  363 aa AbrB protein n.s. ●○○○○ -0.57 -0.572743348449563
Vibrio parahaemolyticus RIMD 2210633  VPA_1499  BAC62842.1  Q87G18  lldD  379 aa L-lactate dehydrogenase n.s. ●○○○○ -0.57 -0.572442155489845
Serratia marcescens Strain UMH9  BVG96_20315  ASL99823.1  207 aa protein disulfide oxidoreductase DsbA n.s. ●○○○○ -0.57 -0.572357048135536
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1656  CBW17751.1  A0A0H3NDH7  trpC  452 aa Indole-3-glycerol phosphate synthase n.s. ●○○○○ -0.57 -0.57158027645414
Mycobacterium avium subsp. paratuberculosis K10  MAP_0442  AAS02759.1  Q743Z9  424 aa hypothetical protein n.s. ●○○○○ -0.57 -0.571524859557963
Mycobacterium avium subsp. paratuberculosis K10  MAP_1155  AAS03472.1  Q741D6  320 aa hypothetical protein n.s. ●○○○○ -0.57 -0.571370517558432
Vibrio parahaemolyticus RIMD 2210633  VPA_0699  BAC62042.1  Q87IA7  375 aa hypothetical protein n.s. ●○○○○ -0.57 -0.571342440864593
Serratia marcescens Strain UMH9  BVG96_20715  ASL99896.1  188 aa DNA-3-methyladenine glycosidase n.s. ●○○○○ -0.57 -0.571313656066725
Vibrio parahaemolyticus RIMD 2210633  VP_0842  BAC59105.1  Q87RF5  429 aa citrate synthase n.s. ●○○○○ -0.57 -0.571117064688813
Escherichia coli CFT073  c0048  AAN78546.1  P60585  caiA  380 aa Crotonobetainyl-CoA dehydrogenase n.s. ●○○○○ -0.57 -0.57083148566547
Serratia marcescens Strain UMH9  BVG96_09470  ASL97837.1  465 aa hypothetical protein n.s. ●○○○○ -0.57 -0.570648597679076
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0968  CBW17065.1  A0A0H3NAB4  177 aa predicted bacteriophage protein n.s. ●○○○○ -0.57 -0.570609179909394
Streptococcus pyogenes M1 5448  SP5448_00565  WP_010921791.1  239 aa metal ABC transporter ATP-binding protein n.s. ●○○○○ -0.57 -0.570249101671451
Mycobacterium avium subsp. paratuberculosis K10  MAP_3600  AAS06150.1  Q73TW8  74 aa hypothetical protein n.s. ●○○○○ -0.57 -0.570030896137493
Streptococcus pyogenes M1 5448  SP5448_08850  WP_002992103.1  102 aa PTS sugar transporter subunit IIB n.s. ●○○○○ -0.57 -0.569960700722032
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1022  CBW17118.1  A0A0H3NAE4  259 aa hypothetical transcriptional regulator n.s. ●○○○○ -0.57 -0.569889136334157
Escherichia coli CFT073  c1634  AAN80099.1  Q8FI24  nhaB  531 aa Na(+)/H(+) antiporter 2 n.s. ●○○○○ -0.57 -0.569852776827685
Vibrio parahaemolyticus RIMD 2210633  VP_2217  BAC60480.1  Q87ML4  184 aa thiol:disulfide interchange protein DsbE n.s. ●○○○○ -0.57 -0.569734765605548
Serratia marcescens Strain UMH9  BVG96_11025  ASL98120.1  432 aa peroxidase n.s. ●○○○○ -0.57 -0.569712946671424
Serratia marcescens Strain UMH9  BVG96_12360  ASL98371.1  306 aa citrate (pro-3S)-lyase subunit beta n.s. ●○○○○ -0.57 -0.569622082229218
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0669  CBW16768.1  A0A0H3N9J0  ybfM  468 aa hypothetical outer membrane protein n.s. ●○○○○ -0.57 -0.569503659976886
Escherichia coli CFT073  c3382  AAN81827.1  A0A0H2VA52  ygdK  147 aa Hypothetical protein ygdK n.s. ●○○○○ -0.57 -0.569405225864964
Mycobacterium avium subsp. paratuberculosis K10  MAP_3420c  AAS05970.1  Q73UE8  379 aa hypothetical protein n.s. ●○○○○ -0.57 -0.569362443246921
Mycobacterium avium subsp. paratuberculosis K10  MAP_0106c  AAS02423.1  Q745A5  343 aa hypothetical protein n.s. ●○○○○ -0.57 -0.569292902962276
Streptococcus pyogenes M1 5448  SP5448_06120  WP_011285487.1  165 aa dihydrofolate reductase n.s. ●○○○○ -0.57 -0.569095497873774
Mycobacterium avium subsp. paratuberculosis K10  MAP_3713c  AAS06263.1  Q73TK5  426 aa hypothetical protein n.s. ●○○○○ -0.57 -0.569031625190037
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0760  WP_002854810.1  A0A0H3P9N2  144 aa filamentous hemagglutinin N-terminal domain-containing protein n.s. ●○○○○ -0.57 -0.569019603761
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0760  WP_009882410.1  A0A0H3P9N2  481 aa hypothetical protein n.s. ●○○○○ -0.57 -0.569019603761
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0760  WP_009882413.1  A0A0H3P9N2  309 aa hypothetical protein n.s. ●○○○○ -0.57 -0.569019603761
Escherichia coli CFT073  c2471  AAN80930.1  A0A0H2V9T5  244 aa Hypothetical protein n.s. ●○○○○ -0.57 -0.569018288345157
Escherichia coli CFT073  c0401  AAN78882.1  Q8FKL3  ecpD  547 aa Hypothetical protein yagW n.s. ●○○○○ -0.57 -0.568968992183678
Streptococcus pyogenes M1 5448  SP5448_04775  WP_002984482.1  180 aa TetR/AcrR family transcriptional regulator n.s. ●○○○○ -0.57 -0.568903230574161
Mycobacterium avium subsp. paratuberculosis K10  MAP_0569  AAS02886.1  Q743M2  533 aa hypothetical protein n.s. ●○○○○ -0.57 -0.568826723972542
Mycobacterium avium subsp. paratuberculosis K10  MAP_1571  AAS03888.1  Q73ZN0  adhA  343 aa AdhA_1 n.s. ●○○○○ -0.57 -0.568825561562868
Porphyromonas gingivalis ATCC 33277  PGN_0781  WP_012457773.1  B2RIV5  topA  788 aa type I DNA topoisomerase n.s. ●○○○○ -0.57 -0.568761435044064
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0074  WP_002868975.1  A0A0H3PCJ6  449 aa DUF2130 domain-containing protein n.s. ●○○○○ -0.57 -0.568687765743
Serratia marcescens Strain UMH9  BVG96_08320  ASL97619.1  112 aa hypothetical protein n.s. ●○○○○ -0.57 -0.568654523518118
Streptococcus pyogenes M1 5448  SP5448_06615  WP_011285471.1  179 aa DNA/RNA non-specific endonuclease n.s. ●○○○○ -0.57 -0.568614829624741
Streptococcus pyogenes M1 5448  SP5448_06615  WP_020750185.1  373 aa phenylalanine--tRNA ligase subunit alpha n.s. ●○○○○ -0.57 -0.568614829624741
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1505  WP_002851537.1  A0A0H3P9U8  63 aa twin-arginine translocation signal domain-containing protein n.s. ●○○○○ -0.57 -0.56857557085
Vibrio parahaemolyticus RIMD 2210633  VP_2233  BAC60496.1  Q87MK2  295 aa flagellar biosynthesis protein FlhG n.s. ●○○○○ -0.57 -0.568329600764882
Serratia marcescens Strain UMH9  BVG96_23495  ASM00396.1  346 aa 16S rRNA (guanine(1207)-N(2))-methyltransferase n.s. ●○○○○ -0.57 -0.568147671775653
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0295  CBW16396.1  A0A0H3NHT3  safA  170 aa salmonella atypical fimbria lipoprotein n.s. ●○○○○ -0.57 -0.568028627332747
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0941  WP_002853706.1  A0A0H3PGH7  446 aa sodium-dependent transporter n.s. ●○○○○ -0.57 -0.567849393149
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1961  CBW18058.1  A0A0H3NI66  301 aa predicted bacteriophage protein n.s. ●○○○○ -0.57 -0.567747510946593
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3009  CBW19108.1  A0A0H3NRG0  210 aa conserved hypothetical protein n.s. ●○○○○ -0.57 -0.567556291224299
Mycobacterium avium subsp. paratuberculosis K10  MAP_2122  AAS04439.1  Q73Y36  430 aa hypothetical protein n.s. ●○○○○ -0.57 -0.567478273415204
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