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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli CFT073  c3072  AAN81522.1  A0A0H2VB31  yphH  399 aa Hypothetical protein yphH n.s. ●○○○○ -0.28 -0.277042662306646
Escherichia coli CFT073  c2109  AAN80569.1  P0A6X8  ihfA  99 aa Integration host factor alpha-subunit n.s. ●○○○○ -0.28 -0.27641188116885
Escherichia coli CFT073  c3268  AAN81717.1  A0A0H2VBG4  hypF  774 aa Hydrogenase maturation protein hypF n.s. ●○○○○ -0.28 -0.276268853506456
Escherichia coli CFT073  c0170  AAN78664.1  A0A0H2V462  htrE  862 aa Outer membrane usher protein htrE precursor n.s. ●○○○○ -0.28 -0.276018849791512
Escherichia coli CFT073  c2817  AAN81271.1  Q8FFK3  nuoN  485 aa NADH dehydrogenase I chain N n.s. ●○○○○ -0.27 -0.274987098625745
Escherichia coli CFT073  c2984  AAN81434.1  P65644  eutT  267 aa Ethanolamine utilization cobalamin adenosyltransferase n.s. ●○○○○ -0.27 -0.272499196954522
Escherichia coli CFT073  c3552  AAN82000.1  A0A0H2VAM7  nupG  434 aa Nucleoside permease nupG n.s. ●○○○○ -0.27 -0.272499196954522
Escherichia coli CFT073  c2449  AAN80908.1  A0A0H2VAQ7  423 aa Prophage P4 integrase n.s. ●○○○○ -0.27 -0.271525360762192
Escherichia coli CFT073  c3995  AAN82435.1  Q8FD51  aaeB  655 aa Hypothetical protein yhcP n.s. ●○○○○ -0.27 -0.271246467300504
Escherichia coli CFT073  c0694  AAN79169.1  P0AE09  ahpC  187 aa Alkyl hydroperoxide reductase C22 protein n.s. ●○○○○ -0.27 -0.269141085765168
Escherichia coli CFT073  c0693  AAN79168.1  A0A0H2V544  171 aa Hypothetical protein n.s. ●○○○○ -0.27 -0.269141085765168
Escherichia coli CFT073  c1186  AAN79648.1  A0A0H2V610  409 aa Putative beta-ketoacyl-ACP synthase n.s. ●○○○○ -0.27 -0.265203525961936
Escherichia coli CFT073  c2994  AAN81444.1  Q8FF87  nudK  200 aa Hypothetical protein yffH n.s. ●○○○○ -0.26 -0.264306768767365
Escherichia coli CFT073  c1067  AAN79535.1  A0A0H2V7W4  ycbB  615 aa Hypothetical protein ycbB n.s. ●○○○○ -0.26 -0.263839830824653
Escherichia coli CFT073  c2875  AAN81325.1  P63609  aroC  362 aa Chorismate synthase n.s. ●○○○○ -0.26 -0.263604533976213
Escherichia coli CFT073  c0929  AAN79402.1  A0A0H2V7N3  272 aa Protein ybjI n.s. ●○○○○ -0.26 -0.262382466308803
Escherichia coli CFT073  c3789  AAN82233.1  P0A8H4  zupT  271 aa Zinc transporter zupT n.s. ●○○○○ -0.26 -0.26102889470542
Escherichia coli CFT073  c4002  AAN82442.1  Q8FD47  yhdE  197 aa Maf-like protein yhdE n.s. ●○○○○ -0.26 -0.2602273349733
Escherichia coli CFT073  c2530  AAN80984.1  P64522  yeeT  73 aa Hypothetical protein yeeT n.s. ●○○○○ -0.26 -0.260014527535977
Escherichia coli CFT073  c4325  AAN82761.1  Q8FCI8  mdtF  1037 aa Hypothetical protein yhiV n.s. ●○○○○ -0.26 -0.259790785287499
Escherichia coli CFT073  c0910  AAN79383.1  Q8FJL3  fsaA  244 aa Fructose-6-phosphate aldolase 1 n.s. ●○○○○ -0.25 -0.253361453557372
Escherichia coli CFT073  c0660  AAN79135.1  Q8CWA2  cusB  407 aa Putative copper efflux system protein cusB precursor n.s. ●○○○○ -0.25 -0.25063110578189
Escherichia coli CFT073  c5204  AAN83626.1  A0A0H2VDI2  pgtA  418 aa Transport activator n.s. ●○○○○ -0.25 -0.250329218239062
Escherichia coli CFT073  c3847  AAN82292.1  Q8FDE0  sstT  414 aa Hypothetical symporter ygjU n.s. ●○○○○ -0.25 -0.24688820653469
Escherichia coli CFT073  c2603  AAN81059.1  Q8FG02  mdtD  471 aa Hypothetical transport protein yegB n.s. ●○○○○ -0.25 -0.245909739839207
Escherichia coli CFT073  c1334  AAN79807.1  Q8FIR0  yceH  215 aa Hypothetical protein yceH n.s. ●○○○○ -0.24 -0.243751622299219
Escherichia coli CFT073  c3462  AAN81907.1  A0A0H2VA89  455 aa Hypothetical protein yjcD n.s. ●○○○○ -0.24 -0.243150502843917
Escherichia coli CFT073  c0490  AAN78968.1  A0A0H2V6T6  phoA  494 aa Alkaline phosphatase precursor n.s. ●○○○○ -0.24 -0.24266486652983
Escherichia coli CFT073  c1577  AAN80046.1  A0A0H2V6P7  124 aa Putative head-tail joining protein of prophage n.s. ●○○○○ -0.24 -0.241696225541906
Escherichia coli CFT073  c1249  AAN79706.1  A0A0H2V625  64 aa Hypothetical protein n.s. ●○○○○ -0.24 -0.23770981669119
Escherichia coli CFT073  c3297  AAN81746.1  A0A0H2VA68  ltnD  302 aa Hypothetical oxidoreductase ygbJ n.s. ●○○○○ -0.24 -0.237430195579203
Escherichia coli CFT073  c0057  AAN78553.1  Q8FLA1  kefC  620 aa Glutathione-regulated potassium-efflux system protein kefC n.s. ●○○○○ -0.24 -0.237127557237545
Escherichia coli CFT073  c3171  AAN81623.1  A0A0H2VC70  533 aa Putative capsid structural protein of prophage n.s. ●○○○○ -0.24 -0.23628274260767
Escherichia coli CFT073  c0360  AAN78841.1  A0A0H2V553  415 aa Hypothetical protein n.s. ●○○○○ -0.23 -0.233455893426031
Escherichia coli CFT073  c3882  AAN82323.1  A0A0H2VB16  yhaU  444 aa Probable galactarate transporter n.s. ●○○○○ -0.23 -0.232790039390891
Escherichia coli CFT073  c4166  AAN82604.1  A0A0H2VBJ1  mrcA  858 aa Penicillin-binding protein 1A n.s. ●○○○○ -0.23 -0.229374861542169
Escherichia coli CFT073  c4731  AAN83164.1  A0A0H2VFA6  yigA  235 aa Hypothetical protein yigA n.s. ●○○○○ -0.23 -0.229316688442418
Escherichia coli CFT073  c4842  AAN83271.1  P0AEL1  fdoI  211 aa Formate dehydrogenase n.s. ●○○○○ -0.23 -0.22755149142889
Escherichia coli CFT073  c3922  AAN82363.1  P60341  truB  314 aa tRNA pseudouridine synthase B n.s. ●○○○○ -0.23 -0.227255866001196
Escherichia coli CFT073  c4344  AAN82780.1  A0A0H2VEI6  yhjN  808 aa Cyclic di-GMP binding protein precursor n.s. ●○○○○ -0.23 -0.226554793068975
Escherichia coli CFT073  c3906  AAN82347.1  A0A0H2VB29  yraR  211 aa Hypothetical protein yraR n.s. ●○○○○ -0.22 -0.224840143078612
Escherichia coli CFT073  c3833  AAN82278.1  A0A0H2VAZ6  ebgA  1089 aa Evolved beta-galactosidase alpha-subunit n.s. ●○○○○ -0.22 -0.223237939127157
Escherichia coli CFT073  c0729  AAN79202.1  A0A0H2V556  phpB  204 aa Alpha-ribazole-5'-phosphate phosphatase n.s. ●○○○○ -0.22 -0.22128291177767
Escherichia coli CFT073  c3510  AAN81958.1  A0A0H2VCT3  236 aa Putative ATP-binding protein of ABC transport system n.s. ●○○○○ -0.22 -0.221144461831665
Escherichia coli CFT073  c3687  AAN82135.1  P62587  kpsE  382 aa KpsE protein n.s. ●○○○○ -0.22 -0.220154450794785
Escherichia coli CFT073  c0197  AAN78691.1  A0A0H2V4U0  htrA  474 aa Protease do precursor n.s. ●○○○○ -0.22 -0.218879941174051
Escherichia coli CFT073  c3726  AAN82170.1  A0A0H2VAT1  yghU  304 aa Hypothetical GST-like protein yghU n.s. ●○○○○ -0.22 -0.218560870967413
Escherichia coli CFT073  c0884  AAN79357.1  A0A0H2V5F8  ybiB  320 aa Hypothetical protein ybiB n.s. ●○○○○ -0.22 -0.217885044138874
Escherichia coli CFT073  c2428  AAN80887.1  A0A0H2VAN4  965 aa Hypothetical protein n.s. ●○○○○ -0.22 -0.216410783888112
Escherichia coli CFT073  c2667  AAN81123.1  P0AD18  yohC  203 aa Hypothetical protein yohC n.s. ●○○○○ -0.22 -0.215851162010965
Escherichia coli CFT073  c3254  AAN81705.1  P0A6G4  pncC  166 aa Protein ygaD n.s. ●○○○○ -0.22 -0.215479348581239
Escherichia coli CFT073  c2962  AAN81412.1  Q8FFA9  murP  474 aa Putative PTS system IIBC component yfeV n.s. ●○○○○ -0.21 -0.211560585659436
Escherichia coli CFT073  c1203  AAN79665.1  A0A0H2V620  352 aa Putative O-methyltransferase n.s. ●○○○○ -0.21 -0.206698577706568
Escherichia coli CFT073  c3267  AAN81716.1  Q8FEN4  norW  377 aa FlRd-NAD(+) reductase n.s. ●○○○○ -0.2 -0.203440032542087
Escherichia coli CFT073  c0188  AAN78682.1  A0A0H2V634  fhuB  660 aa Ferrichrome transport system permease protein fhuB n.s. ●○○○○ -0.2 -0.203160519617372
Escherichia coli CFT073  c2944  AAN81394.1  A0A0H2VAS7  72 aa Conserved hypothetical protein n.s. ●○○○○ -0.2 -0.202574853825402
Escherichia coli CFT073  c0994  AAN79467.1  P0AE31  artM  222 aa Arginine transport system permease protein artM n.s. ●○○○○ -0.2 -0.201803158895955
Escherichia coli CFT073  c4878  AAN83306.1  Q8FBC3  glpK  537 aa Glycerol kinase n.s. ●○○○○ -0.2 -0.201197490638528
Escherichia coli CFT073  c2249  AAN80708.1  A0A0H2V7Y8  yebY  113 aa Hypothetical protein yebY precursor n.s. ●○○○○ -0.2 -0.197284039065025
Escherichia coli CFT073  c5111  AAN83535.1  Q8FAV1  phnC  262 aa Phosphonates transport ATP-binding protein phnC n.s. ●○○○○ -0.2 -0.196999460330331
Escherichia coli CFT073  c3204  AAN81656.1  A0A0H2VA04  390 aa Hypothetical protein n.s. ●○○○○ -0.19 -0.194712253408997
Escherichia coli CFT073  c3429  AAN81874.1  A0A0H2VAF4  346 aa Tas protein n.s. ●○○○○ -0.19 -0.193728376257607
Escherichia coli CFT073  c1145  AAN79613.1  Q8FJ44  rutE  196 aa Putative NADH dehydrogenase/NAD(P)H nitroreductase ycdI n.s. ●○○○○ -0.19 -0.192825448804481
Escherichia coli CFT073  c0901  AAN79374.1  A0A0H2V5H9  ybiP  527 aa Hypothetical protein ybiP n.s. ●○○○○ -0.19 -0.192076948812916
Escherichia coli CFT073  c1273  AAN79747.1  A0A0H2V731  1091 aa Antigen 43 precursor n.s. ●○○○○ -0.19 -0.191738360366871
Escherichia coli CFT073  c0488  AAN78966.1  A0A0H2V4T1  40 aa Hypothetical protein n.s. ●○○○○ -0.19 -0.191116728868985
Escherichia coli CFT073  c4127  AAN82565.1  A0A0H2VBH0  yheS  637 aa Hypothetical ABC transporter ATP-binding protein yheS n.s. ●○○○○ -0.19 -0.190476247334867
Escherichia coli CFT073  c5385  AAN83807.1  A0A0H2VGG6  109 aa Hypothetical protein n.s. ●○○○○ -0.19 -0.188867898039829
Escherichia coli CFT073  c0165  AAN78659.1  Q8FL30  panB  264 aa 3-methyl-2-oxobutanoate hydroxymethyltransferase n.s. ●○○○○ -0.19 -0.188680834404792
Escherichia coli CFT073  c0005  AAN78505.1  A0A0H2V5R3  thrC  428 aa Threonine synthase n.s. ●○○○○ -0.19 -0.187359422786772
Escherichia coli CFT073  c0367  AAN78848.1  A0A0H2V4K2  158 aa Hypothetical protein n.s. ●○○○○ -0.19 -0.185175037789275
Escherichia coli CFT073  c2841  AAN81295.1  A0A0H2VBH8  yfcC  513 aa Hypothetical protein yfcC n.s. ●○○○○ -0.18 -0.183029237722662
Escherichia coli CFT073  c1257  AAN79731.1  A0A0H2V665  120 aa Putative conserved protein n.s. ●○○○○ -0.18 -0.181478301003034
Escherichia coli CFT073  c3711  AAN82155.1  A0A0H2VB04  yghO  402 aa Hypothetical protein yghO n.s. ●○○○○ -0.18 -0.180553928268792
Escherichia coli CFT073  c3844  AAN82289.1  A0A0H2VB50  ygjQ  233 aa Hypothetical protein ygjQ n.s. ●○○○○ -0.18 -0.18049701198245
Escherichia coli CFT073  c3625  AAN82073.1  A0A0H2VAK1  iucC  580 aa IucC protein n.s. ●○○○○ -0.18 -0.180452487759204
Escherichia coli CFT073  c0750  AAN79223.1  A0A0H2V5V9  nagD  250 aa NagD protein n.s. ●○○○○ -0.18 -0.177720379533383
Escherichia coli CFT073  c1589  AAN80057.1  A0A0H2V704  210 aa Putative tail component of prophage n.s. ●○○○○ -0.18 -0.17597535115875
Escherichia coli CFT073  c0430  AAN78911.1  A0A0H2V4M2  200 aa Type 1 fimbriae Regulatory protein fimB n.s. ●○○○○ -0.18 -0.175270912831643
Escherichia coli CFT073  c3553  AAN82001.1  A0A0H2VCV9  speC  711 aa Ornithine decarboxylase, constitutive n.s. ●○○○○ -0.18 -0.17525586418073
Escherichia coli CFT073  c4193  AAN82631.1  A0A0H2VD57  malQ  694 aa 4-alpha-glucanotransferase n.s. ●○○○○ -0.17 -0.174560874941291
Escherichia coli CFT073  c1074  AAN79542.1  A0A0H2V5V2  61 aa Hypothetical protein n.s. ●○○○○ -0.17 -0.17254240415367
Escherichia coli CFT073  c1073  AAN79541.1  Q8FJ98  pncB  416 aa Nicotinate phosphoribosyltransferase n.s. ●○○○○ -0.17 -0.17254240415367
Escherichia coli CFT073  c3978  AAN82418.1  Q8FD59  nanT1  506 aa Putative sialic acid transporter n.s. ●○○○○ -0.17 -0.169428049875534
Escherichia coli CFT073  c3160  AAN81612.1  A0A0H2V9W8  853 aa Putative tail component of prophage n.s. ●○○○○ -0.17 -0.169214336831836
Escherichia coli CFT073  c5427  AAN83847.1  A0A0H2VDW5  yjiA  331 aa Hypothetical protein yjiA n.s. ●○○○○ -0.16 -0.163814976388956
Escherichia coli CFT073  c3770  AAN82214.1  A0A0H2VCI7  295 aa Hypothetical protein n.s. ●○○○○ -0.16 -0.163190051045154
Escherichia coli CFT073  c1618  AAN80083.1  A0A0H2V6W5  57 aa Hypothetical protein n.s. ●○○○○ -0.16 -0.16214795151548
Escherichia coli CFT073  c0476  AAN78954.1  A0A0H2V6S8  tauD  283 aa Alpha-ketoglutarate-dependent taurine dioxygenase n.s. ●○○○○ -0.16 -0.161742150009839
Escherichia coli CFT073  c4981  AAN83407.1  A0A0H2VEM5  409 aa Putative oxidoreductase n.s. ●○○○○ -0.16 -0.161431734851046
Escherichia coli CFT073  c1957  AAN80414.1  A0A0H2V9P5  104 aa PTS system, cellobiose-specific IIA component n.s. ●○○○○ -0.16 -0.161062816150528
Escherichia coli CFT073  c0083  AAN78579.1  A0A0H2V5U8  yabK  536 aa Thiamine transport system permease protein thiP n.s. ●○○○○ -0.16 -0.160668703332399
Escherichia coli CFT073  c0941  AAN79414.1  A0A0H2V5K8  285 aa DNA adenine methylase n.s. ●○○○○ -0.16 -0.158339506088549
Escherichia coli CFT073  c5418  AAN83838.1  A0A0H2VDR8  yjiM  390 aa Hypothetical protein yjiM n.s. ●○○○○ -0.16 -0.157887452235025
Escherichia coli CFT073  c4186  AAN82624.1  Q8FCT7  feoB  777 aa Ferrous iron transport protein B n.s. ●○○○○ -0.16 -0.15737517555169
Escherichia coli CFT073  c3754  AAN82198.1  A0A0H2VCH4  327 aa Putative c4-dicarboxylate transport system binding protein n.s. ●○○○○ -0.16 -0.155731007724431
Escherichia coli CFT073  c2966  AAN81416.1  A0A0H2V9I1  yfeY  191 aa Hypothetical protein yfeY precursor n.s. ●○○○○ -0.15 -0.153636698968964
Escherichia coli CFT073  c0995  AAN79468.1  P0AE35  artQ  238 aa Arginine transport system permease protein artQ n.s. ●○○○○ -0.15 -0.153343223404783
Escherichia coli CFT073  c3334  AAN81782.1  A0A0H2VA08  ygcE  492 aa Hypothetical sugar kinase ygcE n.s. ●○○○○ -0.15 -0.153143928146592
Escherichia coli CFT073  c4024  AAN82464.1  P0A8T2  prmA  293 aa Ribosomal protein L11 methyltransferase n.s. ●○○○○ -0.15 -0.151815742049643
Retrieved entries 1,301–1,400 out of 3,048 total in 49.8 ms (Link to these results)