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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli CFT073  c0458  AAN78937.1  A0A0H2V4Q5  lacY  417 aa Lactose permease n.s. ●○○○○ -0.15 -0.151772424301523
Escherichia coli CFT073  c0402  AAN78883.1  Q8CWC1  ecpC  841 aa Hypothetical protein yagX precursor n.s. ●○○○○ -0.15 -0.150613315387443
Escherichia coli CFT073  c0435  AAN78916.1  A0A0H2V4P1  364 aa Hypothetical protein yahA n.s. ●○○○○ -0.15 -0.149318451942259
Escherichia coli CFT073  c2872  AAN81322.1  A0A0H2VAM6  yfcM  182 aa Hypothetical protein yfcM n.s. ●○○○○ -0.15 -0.145491316902047
Escherichia coli CFT073  c2494  AAN80950.1  A0A0H2VAU9  321 aa Hypothetical protein n.s. ●○○○○ -0.14 -0.14449816875208
Escherichia coli CFT073  c2684  AAN81140.1  P0AEE6  mglB  332 aa D-galactose-binding periplasmic protein precursor n.s. ●○○○○ -0.14 -0.144142716121418
Escherichia coli CFT073  c0851  AAN79324.1  A0A0H2V5D7  gipA  376 aa Peyer's patch-specific virulence factor GipA n.s. ●○○○○ -0.14 -0.144081557343609
Escherichia coli CFT073  c0420  AAN78901.1  A0A0H2V4L2  ykgC  450 aa Probable pyridine nucleotide-disulfide oxidoreductase ykgC n.s. ●○○○○ -0.14 -0.144081557343594
Escherichia coli CFT073  c0177  AAN78671.1  Q8FL25  gluQ  308 aa Hypothetical protein yadB n.s. ●○○○○ -0.14 -0.143894641287187
Escherichia coli CFT073  c4419  AAN82855.1  Q8FCB6  yibT  69 aa Hypothetical protein n.s. ●○○○○ -0.14 -0.142795991787159
Escherichia coli CFT073  c0407  AAN78888.1  P0A7N2  rpmE2  88 aa 50S ribosomal protein L31 type B-1 n.s. ●○○○○ -0.14 -0.142135272900243
Escherichia coli CFT073  c0185  AAN78679.1  A0A0H2V4T4  fhuA  752 aa Ferrichrome-iron receptor precursor n.s. ●○○○○ -0.14 -0.138620639876329
Escherichia coli CFT073  c5419  AAN83839.1  A0A0H2VE87  yjiN  438 aa Hypothetical protein yjiN n.s. ●○○○○ -0.14 -0.138620639876329
Escherichia coli CFT073  c3172  AAN81624.1  P68659  68 aa Putative head-tail joining protein of prophage n.s. ●○○○○ -0.14 -0.137473186904796
Escherichia coli CFT073  c1172  AAN79640.1  A0A0H2V5Z6  85 aa Hypothetical protein n.s. ●○○○○ -0.14 -0.137058850886122
Escherichia coli CFT073  c1173  AAN79641.1  A0A0H2V6T4  68 aa Hypothetical protein n.s. ●○○○○ -0.14 -0.137058850886122
Escherichia coli CFT073  c0480  AAN78958.1  A0A0H2V4S6  yaiH  385 aa Penicillin-binding protein ampH n.s. ●○○○○ -0.14 -0.136546377611485
Escherichia coli CFT073  c3011  AAN81461.1  A0A0H2V9K6  yfgC  487 aa Hypothetical protein yfgC precursor n.s. ●○○○○ -0.14 -0.135030633436102
Escherichia coli CFT073  c0926  AAN79399.1  A0A0H2V5I8  ybjG  198 aa Hypothetical protein ybjG n.s. ●○○○○ -0.13 -0.13488833749392
Escherichia coli CFT073  c5035  AAN83461.1  A0A0H2VD02  472 aa Putative 2-oxoglutarate dehydrogenase n.s. ●○○○○ -0.13 -0.13432668346596
Escherichia coli CFT073  c0597  AAN79075.1  P0AEW7  gsk  434 aa Inosine-guanosine kinase n.s. ●○○○○ -0.13 -0.13374327241073
Escherichia coli CFT073  c1558  AAN80027.1  A0A0H2V6N4  46 aa Hypothetical protein n.s. ●○○○○ -0.13 -0.132758357525803
Escherichia coli CFT073  c0916  AAN79389.1  Q8FJK9  gsiC  306 aa Hypothetical ABC transporter permease protein yliC n.s. ●○○○○ -0.13 -0.132374476332617
Escherichia coli CFT073  c4893  AAN83321.1  A0A0H2VD51  metL  810 aa AKII-HDII protein n.s. ●○○○○ -0.13 -0.130498767418806
Escherichia coli CFT073  c0700  AAN79175.1  A0A0H2V5T7  ybdS  487 aa Citrate carrier/transporter n.s. ●○○○○ -0.13 -0.128355083951566
Escherichia coli CFT073  c1207  AAN79669.1  A0A0H2V848  537 aa Hypothetical protein n.s. ●○○○○ -0.13 -0.127833466273803
Escherichia coli CFT073  c0953  AAN79426.1  A0A0H2V6D9  183 aa Terminase, endonuclease subunit n.s. ●○○○○ -0.13 -0.125974224228278
Escherichia coli CFT073  c1113  AAN79581.1  P69740  hyaA  381 aa Hydrogenase-1 small chain precursor n.s. ●○○○○ -0.13 -0.125544951061658
Escherichia coli CFT073  c0130  AAN78628.1  A0A0H2V4M0  ampE  284 aa AmpE protein n.s. ●○○○○ -0.13 -0.12518875142677
Escherichia coli CFT073  c2713  AAN81167.1  A0A0H2VAD5  rtn  518 aa Rtn protein n.s. ●○○○○ -0.12 -0.124812601529284
Escherichia coli CFT073  c0125  AAN78623.1  A0A0H2V4L4  hofC  400 aa Protein transport protein hofC n.s. ●○○○○ -0.12 -0.123312140499841
Escherichia coli CFT073  c4929  AAN83357.1  Q8CVJ0  btuB  629 aa Vitamin B12 receptor precursor n.s. ●○○○○ -0.12 -0.122430344638013
Escherichia coli CFT073  c0885  AAN79358.1  A0A0H2V655  ybiC  361 aa Hypothetical oxidoreductase ybiC n.s. ●○○○○ -0.12 -0.12233713139051
Escherichia coli CFT073  c0184  AAN78678.1  A0A0H2V471  60 aa Hypothetical protein n.s. ●○○○○ -0.12 -0.118168838947421
Escherichia coli CFT073  c3139  AAN81589.1  P0A938  bamE  113 aa Small protein A n.s. ●○○○○ -0.12 -0.117687956175328
Escherichia coli CFT073  c3454  AAN81899.1  A0A0H2VAA2  yqeC  256 aa Hypothetical protein yqeC n.s. ●○○○○ -0.12 -0.115532430740177
Escherichia coli CFT073  c1190  AAN79652.1  A0A0H2V5Y2  194 aa Conserved hypothetical protein n.s. ●○○○○ -0.11 -0.113255102105494
Escherichia coli CFT073  c4637  AAN83069.1  A0A0H2VF69  yieG  445 aa Hypothetical protein yieG n.s. ●○○○○ -0.11 -0.112691643605132
Escherichia coli CFT073  c4000  AAN82440.1  A0A0H2VBB5  yhdP  1266 aa Hypothetical protein yhdP n.s. ●○○○○ -0.11 -0.110501317228013
Escherichia coli CFT073  c1217  AAN79677.1  A0A0H2V604  102 aa Hypothetical protein n.s. ●○○○○ -0.11 -0.109724735396071
Escherichia coli CFT073  c3461  AAN81906.1  A0A0H2VBU6  ygfP  479 aa Guanine deaminase n.s. ●○○○○ -0.11 -0.109724735396071
Escherichia coli CFT073  c3359  AAN81806.1  P0A8U1  syd  181 aa Syd protein n.s. ●○○○○ -0.11 -0.108285841073246
Escherichia coli CFT073  c1737  AAN80203.1  A0A0H2V792  sohB  349 aa Possible protease sohB n.s. ●○○○○ -0.11 -0.10812841649175
Escherichia coli CFT073  c0244  AAN78734.1  A0A0H2V494  yafB  267 aa 2,5-diketo-D-gluconic acid reductase B n.s. ●○○○○ -0.11 -0.108091726983923
Escherichia coli CFT073  c3230  AAN81682.1  A0A0H2VBD7  proV  400 aa Glycine betaine/L-proline transport ATP-binding protein proV n.s. ●○○○○ -0.11 -0.107973396916956
Escherichia coli CFT073  c0596  AAN79074.1  Q8FK82  aes  319 aa Acetyl esterase n.s. ●○○○○ -0.11 -0.107366647295414
Escherichia coli CFT073  c3464  AAN81909.1  A0A0H2VCQ7  ygfT  644 aa Hypothetical protein ygfT n.s. ●○○○○ -0.11 -0.107350770963144
Escherichia coli CFT073  c3292  AAN81741.1  A0A0H2VCE3  155 aa Potential molybdenum-pterin-binding-protein n.s. ●○○○○ -0.11 -0.105628687823131
Escherichia coli CFT073  c1120  AAN79588.1  A0A0H2V5X9  appB  378 aa Cytochrome BD-II oxidase subunit II n.s. ●○○○○ -0.1 -0.104890034906308
Escherichia coli CFT073  c3098  AAN81547.1  A0A0H2V9J7  nadB  540 aa L-aspartate oxidase n.s. ●○○○○ -0.1 -0.104843353671913
Escherichia coli CFT073  c0674  AAN79149.1  A0A0H2V530  fepE  377 aa Ferric enterobactin transport protein fepE n.s. ●○○○○ -0.1 -0.104044735259692
Escherichia coli CFT073  c1153  AAN79621.1  A0A0H2V810  63 aa Hypothetical protein n.s. ●○○○○ -0.1 -0.101663843731626
Escherichia coli CFT073  c0683  AAN79158.1  A0A0H2V770  entA  248 aa 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase n.s. ●○○○○ -0.1 -0.101572128523764
Escherichia coli CFT073  c2967  AAN81417.1  A0A0H2VBR7  yfeZ  151 aa Hypothetical protein yfeZ n.s. ●○○○○ -0.1 -0.100834508856561
Escherichia coli CFT073  c2582  AAN81037.1  A0A0H2V8R8  wcaD  429 aa Putative colanic acid polymerase n.s. ●○○○○ -0.1 -0.0994531329827888
Escherichia coli CFT073  c3623  AAN82071.1  A0A0H2VAM3  iutA  759 aa IutA protein n.s. ●○○○○ -0.1 -0.0986212137468526
Escherichia coli CFT073  c1301  AAN79774.1  P0AE96  csgE  129 aa Curli production assembly/transport component csgE precursor n.s. ●○○○○ -0.1 -0.0969282519293925
Escherichia coli CFT073  c4163  AAN82601.1  A0A0H2VBE5  yrfB  146 aa Hypothetical protein yrfB n.s. ●○○○○ -0.1 -0.0968822585319705
Escherichia coli CFT073  c4971  AAN83397.1  A0A0H2VFL6  aceB  539 aa Malate synthase A n.s. ●○○○○ -0.09 -0.0942451326110128
Escherichia coli CFT073  c0454  AAN78933.1  A0A0H2V6R6  prpE  628 aa Propionate--CoA ligase n.s. ●○○○○ -0.09 -0.093182938686089
Escherichia coli CFT073  c3437  AAN81882.1  A0A0H2VCN5  ygeA  230 aa Hypothetical protein ygeA n.s. ●○○○○ -0.09 -0.0931080415551987
Escherichia coli CFT073  c0234  AAN78726.1  A0A0H2V4V4  yaeF  277 aa Hypothetical lipoprotein yaeF precursor n.s. ●○○○○ -0.09 -0.0925177901709136
Escherichia coli CFT073  c3472  AAN81920.1  A0A0H2VCR3  recJ  577 aa Single-stranded-DNA-specific exonuclease recJ n.s. ●○○○○ -0.09 -0.0902891284671352
Escherichia coli CFT073  c3208  AAN81660.1  A0A0H2VBC2  ygaF  444 aa Hypothetical protein ygaF n.s. ●○○○○ -0.09 -0.0896917538361911
Escherichia coli CFT073  c3207  AAN81659.1  Q8FES6  glaH  325 aa Hypothetical protein ygaT n.s. ●○○○○ -0.09 -0.0896917538361911
Escherichia coli CFT073  c0413  AAN78894.1  A0A0H2V4M9  329 aa Putative aldo/keto reductase n.s. ●○○○○ -0.09 -0.0878340401443467
Escherichia coli CFT073  c3311  AAN81760.1  P0A841  surE  268 aa Acid phosphatase surE n.s. ●○○○○ -0.09 -0.0878340401443405
Escherichia coli CFT073  c0469  AAN78947.1  A0A0H2V4R5  398 aa Hypothetical protein yaiP n.s. ●○○○○ -0.08 -0.0828900246549153
Escherichia coli CFT073  c0868  AAN79341.1  P0AAC5  ybhL  261 aa Hypothetical protein ybhL n.s. ●○○○○ -0.08 -0.0826448103582467
Escherichia coli CFT073  c2383  AAN80842.1  A0A0H2V8F6  375 aa Outer membrane protein N precursor n.s. ●○○○○ -0.08 -0.0813156953343056
Escherichia coli CFT073  c2959  AAN81409.1  A0A0H2V9H8  cysP  338 aa Thiosulfate-binding protein precursor n.s. ●○○○○ -0.08 -0.0791520910150625
Escherichia coli CFT073  c3408  AAN81853.1  A0A0H2VBR3  526 aa PTS system, maltose and glucose-specific IIABC component n.s. ●○○○○ -0.08 -0.0784266493156909
Escherichia coli CFT073  c4408  AAN82844.1  A0A0H2VC95  aldB  542 aa Aldehyde dehydrogenase B n.s. ●○○○○ -0.08 -0.0769428933836586
Escherichia coli CFT073  c0509  AAN78987.1  A0A0H2V5G6  phoR  431 aa Phosphate regulon sensor protein phoR n.s. ●○○○○ -0.08 -0.0764490861974163
Escherichia coli CFT073  c0149  AAN78643.1  Q8FL39  speD  264 aa S-adenosylmethionine decarboxylase proenzyme n.s. ●○○○○ -0.08 -0.075832373175144
Escherichia coli CFT073  c4489  AAN82925.1  A0A0H2VDP5  yicI  772 aa Putative family 31 glucosidase yicI n.s. ●○○○○ -0.07 -0.0745723353135292
Escherichia coli CFT073  c0448  AAN78927.1  A0A0H2V4Q3  yahN  224 aa Hypothetical protein yahN n.s. ●○○○○ -0.07 -0.0740792284865912
Escherichia coli CFT073  c5032  AAN83458.1  A0A0H2VFQ6  939 aa 2-oxoglutarate dehydrogenase E1 component n.s. ●○○○○ -0.07 -0.0729170976754149
Escherichia coli CFT073  c5341  AAN83762.1  A0A0H2VFB3  mgtA  898 aa Mg(2+) transport ATPase, P-type 1 n.s. ●○○○○ -0.07 -0.0725125673639753
Escherichia coli CFT073  c3387  AAN81832.1  A0A0H2VA58  445 aa Hypothetical protein n.s. ●○○○○ -0.07 -0.0723019612803285
Escherichia coli CFT073  c0085  AAN78581.1  Q8FL80  sgrR  558 aa Hypothetical protein yabN n.s. ●○○○○ -0.07 -0.0717655518778315
Escherichia coli CFT073  c3977  AAN82417.1  P0A762  nanE  243 aa Hypothetical protein yhcJ n.s. ●○○○○ -0.07 -0.0712643714465491
Escherichia coli CFT073  c3976  AAN82416.1  Q8FD60  nanK1  302 aa Hypothetical protein yhcI n.s. ●○○○○ -0.07 -0.0712643714465491
Escherichia coli CFT073  c5018  AAN83444.1  Q8FB30  dusA  331 aa Hypothetical protein yjbN n.s. ●○○○○ -0.07 -0.0700435125932496
Escherichia coli CFT073  c0543  AAN79021.1  P0ABJ2  cyoA  315 aa Ubiquinol oxidase polypeptide II precursor n.s. ●○○○○ -0.07 -0.0690795044689776
Escherichia coli CFT073  c3198  AAN81650.1  A0A0H2V9Q9  170 aa Hypothetical protein n.s. ●○○○○ -0.07 -0.0656561528433986
Escherichia coli CFT073  c5345  AAN83766.1  P0A787  pyrB  311 aa Aspartate carbamoyltransferase catalytic chain n.s. ●○○○○ -0.06 -0.0643767068961681
Escherichia coli CFT073  c0653  AAN79128.1  A0A0H2V532  ybcH  296 aa Hypothetical protein ybcH precursor n.s. ●○○○○ -0.06 -0.0640650621081789
Escherichia coli CFT073  c0441  AAN78922.1  A0A0H2V4Q0  515 aa Hypothetical protein yahF n.s. ●○○○○ -0.06 -0.0640650621081789
Escherichia coli CFT073  c0643  AAN79120.1  A0A0H2V5N8  ybcI  145 aa Hypothetical protein ybcI n.s. ●○○○○ -0.06 -0.0636636645158062
Escherichia coli CFT073  c5461  AAN83881.1  A0A0H2VGJ5  yjjV  259 aa Putative deoxyribonuclease yjjV n.s. ●○○○○ -0.06 -0.0633989273347829
Escherichia coli CFT073  c0789  AAN79262.1  P0AFP7  ybgI  247 aa Hypothetical protein ybgI n.s. ●○○○○ -0.06 -0.0633494173375371
Escherichia coli CFT073  c2916  AAN81366.1  A0A0H2V9F7  yfdZ  412 aa Hypothetical aminotransferase yfdZ n.s. ●○○○○ -0.06 -0.0628136309790963
Escherichia coli CFT073  c2515  AAN80970.1  A0A0H2VAW4  255 aa Putative ABC transporter n.s. ●○○○○ -0.06 -0.0614020595446029
Escherichia coli CFT073  c5298  AAN83719.1  A0A0H2VDY6  425 aa Hexuronate transporter n.s. ●○○○○ -0.06 -0.0596255015271022
Escherichia coli CFT073  c0678  AAN79153.1  Q8FK20  entS  416 aa Hypothetical membrane protein P43 n.s. ●○○○○ -0.06 -0.0592633868078196
Escherichia coli CFT073  c3085  AAN81534.1  A0A0H2V9J2  yfhH  306 aa Hypothetical protein yfhH n.s. ●○○○○ -0.06 -0.0576485207235372
Escherichia coli CFT073  c0933  AAN79406.1  A0A0H2V5L5  323 aa Hypothetical protein n.s. ●○○○○ -0.06 -0.057252943201525
Escherichia coli CFT073  c4721  AAN83154.1  P0ACB8  hemY  398 aa HemY protein n.s. ●○○○○ -0.06 -0.0569182559715573
Escherichia coli CFT073  c2924  AAN81374.1  A0A0H2VBN9  361 aa Putative peptidase ypdF n.s. ●○○○○ -0.06 -0.0569182559715531
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