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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli CFT073  c2605  AAN81061.1  P69229  baeR  240 aa Transcriptional Regulatory protein baeR n.s. ●●●○○ -2.22 -2.21726955041758
Escherichia coli CFT073  c2422  AAN80881.1  A0A0H2V8I8  600 aa Putative inner membrane ABC-transporter n.s. ●●●○○ -2.22 -2.21537232748913
Escherichia coli CFT073  c2203  AAN80662.1  A0A0H2V7W3  163 aa Hypothetical protein n.s. ●●●○○ -2.21 -2.20885166787138
Escherichia coli CFT073  c2022  AAN80482.1  Q8FH94  rsxD  352 aa Electron transport complex protein rnfD n.s. ●●●○○ -2.2 -2.20080983760601
Escherichia coli CFT073  c1968  AAN80428.1  A0A0H2V7F2  486 aa Hypothetical oxidoreductase ydfI n.s. ●●●○○ -2.19 -2.19261178522087
Escherichia coli CFT073  c2717  AAN81171.1  A0A0H2V901  yejF  529 aa Hypothetical ABC transporter ATP-binding protein yejF n.s. ●●●○○ -2.19 -2.19221422895652
Escherichia coli CFT073  c2455  AAN80914.1  A0A0H2V8G4  1120 aa Putative peptide synthetase n.s. ●●●○○ -2.19 -2.19120195186059
Escherichia coli CFT073  c2076  AAN80536.1  A0A0H2V7L8  ynhC  423 aa SufD protein n.s. ●●●○○ -2.18 -2.17732186152964
Escherichia coli CFT073  c1849  AAN80312.1  Q8CW34  mdoD  551 aa Protein ydcG precursor n.s. ●●●○○ -2.17 -2.17182195962091
Escherichia coli CFT073  c1341  AAN79812.1  A0A0H2V688  flgA  219 aa Flagella basal body P-ring formation protein flgA precursor n.s. ●●●○○ -2.17 -2.16677026981113
Escherichia coli CFT073  c1205  AAN79667.1  A0A0H2V5Z4  908 aa Hypothetical protein n.s. ●●●○○ -2.17 -2.16634670902292
Escherichia coli CFT073  c2469  AAN80928.1  A0A0H2VAT2  1352 aa Putative polyketide synthase n.s. ●●●○○ -2.16 -2.16282728673657
Escherichia coli CFT073  c1867  AAN80330.1  A0A0H2V9J0  ydcV  214 aa Hypothetical ABC transporter permease protein ydcV n.s. ●●●○○ -2.16 -2.15856732585429
Escherichia coli CFT073  c1934  AAN80392.1  A0A0H2V7M2  883 aa Outer membrane usher protein fimD precursor n.s. ●●●○○ -2.16 -2.15665133711817
Escherichia coli CFT073  c2453  AAN80912.1  A0A0H2V8L4  819 aa Putative polyketide synthase n.s. ●●●○○ -2.14 -2.13906230530949
Escherichia coli CFT073  c2818  AAN81272.1  A0A0H2V953  nuoM  509 aa NADH dehydrogenase I chain M n.s. ●●●○○ -2.13 -2.13182253349144
Escherichia coli CFT073  c2461  AAN80920.1  A0A0H2V9S6  1603 aa Hypothetical protein n.s. ●●●○○ -2.12 -2.12058477498486
Escherichia coli CFT073  c1765  AAN80231.1  A0A0H2V7A8  457 aa Partial Putative outer membrane channel protein n.s. ●●●○○ -2.12 -2.11866878624874
Escherichia coli CFT073  c1977  AAN80437.1  A0A0H2V7F7  ynfE  808 aa Putative dimethyl sulfoxide reductase chain ynfE precursor n.s. ●●●○○ -2.12 -2.11769209160895
Escherichia coli CFT073  c2202  AAN80661.1  P64497  yoaG  60 aa Hypothetical protein yoaG n.s. ●●●○○ -2.11 -2.11253908347272
Escherichia coli CFT073  c1803  AAN80267.1  A0A0H2V8B1  mppA  544 aa Periplasmic murein peptide-binding protein precursor n.s. ●●●○○ -2.1 -2.10462899986717
Escherichia coli CFT073  c1978  AAN80438.1  A0A0H2V7P8  ynfF  808 aa Probable dimethyl sulfoxide reductase chain ynfF precursor n.s. ●●●○○ -2.1 -2.10429590110043
Escherichia coli CFT073  c1756  AAN80222.1  A0A0H2V722  yciR  661 aa Hypothetical protein yciR n.s. ●●●○○ -2.1 -2.10135139439217
Escherichia coli CFT073  c2067  AAN80527.1  A0A0H2V7L4  ydhV  728 aa Hypothetical protein ydhV n.s. ●●●○○ -2.1 -2.09554931526449
Escherichia coli CFT073  c2021  AAN80481.1  Q8FH95  rsxC  742 aa Electron transport complex protein rnfC n.s. ●●●○○ -2.09 -2.08890007595829
Escherichia coli CFT073  c1338  AAN79809.1  A0A0H2V8C8  mviN  511 aa Virulence factor mviN homolog n.s. ●●●○○ -2.08 -2.0848916815806
Escherichia coli CFT073  c1329  AAN79802.1  Q8FIR2  pyrC  348 aa Dihydroorotase n.s. ●●●○○ -2.07 -2.07313743768766
Escherichia coli CFT073  c1164  AAN79632.1  A0A0H2V5W1  ycdT  496 aa Hypothetical protein ycdT n.s. ●●●○○ -2.07 -2.07017974737405
Escherichia coli CFT073  c1392  AAN79861.1  Q8FIM7  lolD  233 aa Lipoprotein releasing system ATP-binding protein lolD n.s. ●●●○○ -2.07 -2.06851921529523
Escherichia coli CFT073  c1086  AAN79554.1  P0AFM0  pqiA  417 aa Paraquat-inducible protein A n.s. ●●●○○ -2.07 -2.06745213008825
Escherichia coli CFT073  c0553  AAN79031.1  P0A6G8  clpP  207 aa ATP-dependent Clp protease proteolytic subunit n.s. ●●●○○ -2.07 -2.066313350231
Escherichia coli CFT073  c2098  AAN80558.1  A0A0H2V902  ppsA  792 aa Phosphoenolpyruvate synthase n.s. ●●●○○ -2.06 -2.05988401850087
Escherichia coli CFT073  c2086  AAN80546.1  A0A0H2V7M9  ydiN  423 aa Hypothetical transport protein ydiN n.s. ●●●○○ -2.06 -2.05881068265601
Escherichia coli CFT073  c2060  AAN80520.1  A0A0H2V7M7  ydhS  536 aa Hypothetical protein ydhS n.s. ●●●○○ -2.06 -2.05819460398207
Escherichia coli CFT073  c1622  AAN80087.1  P0AEZ4  minD  270 aa Septum site-determining protein minD n.s. ●●●○○ -2.06 -2.0574682955783
Escherichia coli CFT073  c1163  AAN79631.1  A0A0H2V6S7  ycdS  807 aa Hypothetical protein ycdS precursor n.s. ●●●○○ -2.06 -2.0574682955783
Escherichia coli CFT073  c1714  AAN80181.1  Q8FHW7  yciY  94 aa Hypothetical protein n.s. ●●●○○ -2.06 -2.05680682664956
Escherichia coli CFT073  c1447  AAN79916.1  A0A0H2V6K6  530 aa Putative capsid protein of prophage n.s. ●●●○○ -2.06 -2.05513488434479
Escherichia coli CFT073  c2432  AAN80891.1  A0A0H2V8J5  218 aa Putative thioesterase n.s. ●●●○○ -2.05 -2.0534363434314
Escherichia coli CFT073  c1804  AAN80268.1  A0A0H2V728  ynaI  343 aa Hypothetical protein ynaI n.s. ●●●○○ -2.05 -2.04995688380814
Escherichia coli CFT073  c0323  AAN78811.1  A0A0H2V4G4  768 aa Putative exopolygalacturonate lyase n.s. ●●●○○ -2.05 -2.04817462142958
Escherichia coli CFT073  c2895  AAN81345.1  A0A0H2VAP3  2387 aa yapH homolog n.s. ●●●○○ -2.04 -2.04413546293005
Escherichia coli CFT073  c2552  AAN81007.1  Q8FG48  hisF  258 aa Imidazole glycerol phosphate synthase subunit hisF n.s. ●●●○○ -2.04 -2.04264916982888
Escherichia coli CFT073  c2004  AAN80464.1  P0AC34  fumA  548 aa Fumarate hydratase class I, aerobic n.s. ●●●○○ -2.04 -2.04264916982888
Escherichia coli CFT073  c2043  AAN80503.1  A0A0H2V9V3  nemA  365 aa N-ethylmaleimide reductase n.s. ●●●○○ -2.04 -2.0381563083513
Escherichia coli CFT073  c1590  AAN80058.1  A0A0H2V925  1160 aa Putative tail component of prophage n.s. ●●●○○ -2.03 -2.03483616782433
Escherichia coli CFT073  c2813  AAN81267.1  A0A0H2VAJ3  yfbK  580 aa Hypothetical protein yfbK n.s. ●●●○○ -2.03 -2.0296022387028
Escherichia coli CFT073  c2221  AAN80680.1  A0A0H2VA76  yoaD  542 aa Hypothetical protein yoaD n.s. ●●●○○ -2.03 -2.02646354233316
Escherichia coli CFT073  c2019  AAN80479.1  P0A767  rsxA  193 aa Electron transport complex protein rnfA n.s. ●●●○○ -2.02 -2.02144731336688
Escherichia coli CFT073  c0640  AAN79117.1  A0A0H2V740  228 aa Conserved hypothetical protein n.s. ●●●○○ -2.02 -2.02045117380673
Escherichia coli CFT073  c2538  AAN80992.1  A0A0H2V8T0  dacD  390 aa Penicillin-binding protein 6B precursor n.s. ●●●○○ -2.02 -2.01746886944882
Escherichia coli CFT073  c1840  AAN80303.1  A0A0H2V7F8  hrpA  1300 aa ATP-dependent helicase hrpA n.s. ●●●○○ -2.01 -2.01415057553786
Escherichia coli CFT073  c1196  AAN79658.1  A0A0H2V618  125 aa Conserved hypothetical protein n.s. ●●●○○ -2.01 -2.01271616826731
Escherichia coli CFT073  c2246  AAN80705.1  A0A0H2VA86  yebW  91 aa Hypothetical protein yebW n.s. ●●●○○ -2.01 -2.01123377491873
Escherichia coli CFT073  c1848  AAN80311.1  A0A0H2V8E8  ydcJ  447 aa Hypothetical protein ydcJ n.s. ●●●○○ -2.01 -2.01100993294362
Escherichia coli CFT073  c1638  AAN80103.1  P0A6J6  dadA  434 aa D-amino acid dehydrogenase small subunit n.s. ●●●○○ -2.01 -2.00909741876889
Escherichia coli CFT073  c1896  AAN80356.1  A0A0H2V7A2  yddE  297 aa Hypothetical protein yddE n.s. ●●●○○ -2 -2.00138828199829
Escherichia coli CFT073  c0122  AAN78620.1  Q8FL56  zapD  247 aa Hypothetical protein yacF n.s. ●●○○○ -2 -1.99976536732971
Escherichia coli CFT073  c5623  AAN80363.1  A0A0H2V9L3  fdnG  1015 aa Formate dehydrogenase, nitrate-inducible, major subunit n.s. ●●○○○ -2 -1.99808887720915
Escherichia coli CFT073  c2861  AAN81313.1  Q8FFH5  accD  332 aa Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta n.s. ●●○○○ -1.99 -1.99221134833339
Escherichia coli CFT073  c2354  AAN80813.1  A0A0H2V863  fliF  552 aa Flagellar M-ring protein n.s. ●●○○○ -1.99 -1.99221134833339
Escherichia coli CFT073  c1966  AAN80426.1  Q8FHD1  ydfH  228 aa Hypothetical transcriptional regulator ydfH n.s. ●●○○○ -1.99 -1.98961639053156
Escherichia coli CFT073  c0526  AAN79004.1  A0A0H2V6V2  177 aa Hypothetical protein n.s. ●●○○○ -1.99 -1.98631849341976
Escherichia coli CFT073  c0527  AAN79005.1  P0A781  nusB  139 aa N utilization substance protein B n.s. ●●○○○ -1.99 -1.98631849341976
Escherichia coli CFT073  c0782  AAN79255.1  Q8FJV4  kdpB  682 aa Potassium-transporting ATPase B chain n.s. ●●○○○ -1.98 -1.97599099556277
Escherichia coli CFT073  c1847  AAN80310.1  A0A0H2V790  ycdI  354 aa Hypothetical transcriptional regulator ydcI n.s. ●●○○○ -1.97 -1.97440051863113
Escherichia coli CFT073  c1835  AAN80298.1  A0A0H2V9H2  ynbB  298 aa Hypothetical protein ynbB n.s. ●●○○○ -1.97 -1.97363896560662
Escherichia coli CFT073  c3203  AAN81655.1  A0A0H2V9R1  296 aa Hypothetical protein n.s. ●●○○○ -1.97 -1.96804097270486
Escherichia coli CFT073  c1971  AAN80431.1  Q8FHC7  rspA  415 aa Starvation sensing protein rspA n.s. ●●○○○ -1.96 -1.9606649302377
Escherichia coli CFT073  c2097  AAN80557.1  A0A0H2V7Q8  ydiD  566 aa Hypothetical protein ydiD n.s. ●●○○○ -1.96 -1.96006110329546
Escherichia coli CFT073  c1902  AAN80362.1  A0A0H2V7K8  yddG  293 aa Hypothetical protein yddG n.s. ●●○○○ -1.96 -1.95571889178857
Escherichia coli CFT073  c2398  AAN80857.1  A0A0H2V8B5  307 aa Hypothetical protein n.s. ●●○○○ -1.95 -1.95489019264469
Escherichia coli CFT073  c2077  AAN80537.1  A0A0H2V7V5  ynhD  248 aa Probable ATP-dependent transporter sufC n.s. ●●○○○ -1.95 -1.95163383966214
Escherichia coli CFT073  c1958  AAN80415.1  A0A0H2V7H5  453 aa Putative conserved protein n.s. ●●○○○ -1.95 -1.95112628018131
Escherichia coli CFT073  c2253  AAN80712.1  A0A0H2VA95  yobB  218 aa Hypothetical protein yobB n.s. ●●○○○ -1.95 -1.949251226285
Escherichia coli CFT073  c1166  AAN79634.1  A0A0H2V821  605 aa Conserved hypothetical protein n.s. ●●○○○ -1.95 -1.94853595216005
Escherichia coli CFT073  c1495  AAN79964.1  A0A0H2V8S0  584 aa Hypothetical protein n.s. ●●○○○ -1.95 -1.94629000038123
Escherichia coli CFT073  c2006  AAN80466.1  A0A0H2V9T3  ydgA  502 aa Hypothetical protein ydgA n.s. ●●○○○ -1.94 -1.94463256827256
Escherichia coli CFT073  c2102  AAN80562.1  Q8FH30  selO  478 aa Hypothetical protein ydiU n.s. ●●○○○ -1.94 -1.94463256827256
Escherichia coli CFT073  c1259  AAN79733.1  A0A0H2V635  144 aa Hypothetical protein n.s. ●●○○○ -1.94 -1.93898613716782
Escherichia coli CFT073  c2137  AAN80596.1  P69796  chbB  106 aa PTS system, cellobiose-specific IIB component n.s. ●●○○○ -1.94 -1.9386141663697
Escherichia coli CFT073  c1379  AAN79849.1  Q8FIN3  thiK  274 aa Hypothetical protein ycfN n.s. ●●○○○ -1.94 -1.93751818740599
Escherichia coli CFT073  c2284  AAN80741.1  Q8FGQ6  cmoA  247 aa Protein yecO n.s. ●●○○○ -1.93 -1.93257969394871
Escherichia coli CFT073  c1749  AAN80215.1  P0AB59  lapB  389 aa Hypothetical protein yciM precursor n.s. ●●○○○ -1.93 -1.93238785925746
Escherichia coli CFT073  c2848  AAN81302.1  A0A0H2V9B3  hisP  257 aa Histidine transport ATP-binding protein hisP n.s. ●●○○○ -1.93 -1.93075792151721
Escherichia coli CFT073  c1729  AAN80194.1  A0A0H2V787  trpD  531 aa Anthranilate synthase component II n.s. ●●○○○ -1.92 -1.92046219264402
Escherichia coli CFT073  c1331  AAN79804.1  P0AC60  grxB  215 aa Glutaredoxin 2 n.s. ●●○○○ -1.92 -1.92046219264402
Escherichia coli CFT073  c2045  AAN80505.1  P66681  rnt  215 aa Ribonuclease T n.s. ●●○○○ -1.92 -1.92046219264402
Escherichia coli CFT073  c2561  AAN81016.1  A0A0H2V8Q0  381 aa Hypothetical protein n.s. ●●○○○ -1.92 -1.92046219264402
Escherichia coli CFT073  c1791  AAN80257.1  A0A0H2V7C7  ompG  318 aa Outer membrane protein G precursor n.s. ●●○○○ -1.92 -1.92046219264401
Escherichia coli CFT073  c1084  AAN79552.1  Q8FJ88  rlmL  702 aa Hypothetical protein ycbY n.s. ●●○○○ -1.92 -1.9155653140674
Escherichia coli CFT073  c2026  AAN80486.1  Q8FH91  dtpA  500 aa Hypothetical transporter ydgR n.s. ●●○○○ -1.91 -1.9098273091173
Escherichia coli CFT073  c1838  AAN80301.1  A0A0H2V753  220 aa Hypothetical protein n.s. ●●○○○ -1.91 -1.90967501904151
Escherichia coli CFT073  c1710  AAN80177.1  A0A0H2V700  oppD  337 aa Oligopeptide transport ATP-binding protein oppD n.s. ●●○○○ -1.91 -1.90935696843527
Escherichia coli CFT073  c1242  AAN79699.1  A0A0H2V6Z7  focD  892 aa F1C fimbrial usher n.s. ●●○○○ -1.91 -1.90935696843527
Escherichia coli CFT073  c1976  AAN80436.1  A0A0H2V8R2  ynfD  115 aa Hypothetical protein ynfD precursor n.s. ●●○○○ -1.9 -1.90353395934173
Escherichia coli CFT073  c1921  AAN80379.1  Q8FHG6  gadC  511 aa Amino acid antiporter n.s. ●●○○○ -1.9 -1.90327649325443
Escherichia coli CFT073  c2166  AAN80625.1  A0A0H2V7V3  topB  667 aa DNA topoisomerase III n.s. ●●○○○ -1.9 -1.90273732861418
Escherichia coli CFT073  c2586  AAN81042.1  A0A0H2VB13  732 aa Tyrosine-protein kinase wzc n.s. ●●○○○ -1.9 -1.89972894099193
Escherichia coli CFT073  c2799  AAN81253.1  Q8FFL9  arnT  550 aa Hypothetical protein yfbI n.s. ●●○○○ -1.9 -1.89883610819746
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