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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli CFT073  c1197  AAN79659.1  A0A0H2V841  452 aa Putative enzyme n.s. ●●○○○ -1.19 -1.19063808576459
Escherichia coli CFT073  c0772  AAN79245.1  A0A0H2V5A4  ybfE  120 aa Hypothetical protein ybfE n.s. ●●○○○ -1.19 -1.19063808576459
Escherichia coli CFT073  c2990  AAN81440.1  A0A0H2VBT2  tktB  688 aa Transketolase 2 n.s. ●●○○○ -1.19 -1.18503731814234
Escherichia coli CFT073  c1253  AAN79727.1  A0A0H2V707  iroC  1245 aa ATP binding cassette (ABC) transporter homolog n.s. ●●○○○ -1.19 -1.18503731814233
Escherichia coli CFT073  c1136  AAN79604.1  Q8FJ50  cbpA  306 aa Curved DNA-binding protein n.s. ●●○○○ -1.18 -1.18348464987179
Escherichia coli CFT073  c3619  AAN82067.1  Q8FDW4  sat  1299 aa secreted auto transpoter toxin n.s. ●●○○○ -1.18 -1.18203810260076
Escherichia coli CFT073  c1841  AAN80304.1  A0A0H2V9H5  ydcF  266 aa Protein ydcF n.s. ●●○○○ -1.18 -1.17785730073211
Escherichia coli CFT073  c0566  AAN79044.1  P0AAG6  mdlB  631 aa Multidrug resistance-like ATP-binding protein mdlB n.s. ●●○○○ -1.18 -1.17689935983858
Escherichia coli CFT073  c1451  AAN79920.1  A0A0H2V6F5  342 aa Putative capsid protein of prophage n.s. ●●○○○ -1.18 -1.17641499337963
Escherichia coli CFT073  c2968  AAN81418.1  P63420  ypeA  178 aa Hypothetical protein ypeA n.s. ●●○○○ -1.18 -1.17520245024122
Escherichia coli CFT073  c2223  AAN80682.1  P69798  manX  323 aa PTS system, mannose-specific IIAB component n.s. ●●○○○ -1.18 -1.17508175764171
Escherichia coli CFT073  c2807  AAN81261.1  Q8FFL2  menH  252 aa Hypothetical protein yfbB n.s. ●●○○○ -1.17 -1.16946242135509
Escherichia coli CFT073  c0669  AAN79144.1  A0A0H2V524  fepA  746 aa Ferrienterobactin receptor precursor n.s. ●●○○○ -1.17 -1.16935705694363
Escherichia coli CFT073  c1091  AAN79559.1  A0A0H2V7X6  586 aa Putative protease La homolog n.s. ●●○○○ -1.17 -1.16868085171947
Escherichia coli CFT073  c3313  AAN81762.1  Q8FEJ6  ispF  159 aa 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n.s. ●●○○○ -1.17 -1.16849215647627
Escherichia coli CFT073  c2911  AAN81361.1  A0A0H2V9F3  210 aa YfdX protein precursor n.s. ●●○○○ -1.16 -1.16476894390715
Escherichia coli CFT073  c2623  AAN81079.1  P0A992  fbaB  374 aa Fructose-bisphosphate aldolase class I n.s. ●●○○○ -1.16 -1.16449255320432
Escherichia coli CFT073  c2357  AAN80816.1  A0A0H2VAH9  fliH  235 aa Flagellar assembly protein fliH n.s. ●●○○○ -1.16 -1.16415603193516
Escherichia coli CFT073  c2268  AAN80725.1  A0A0H2V7Z8  pykA  527 aa Pyruvate kinase II n.s. ●●○○○ -1.16 -1.16373736236057
Escherichia coli CFT073  c2126  AAN80585.1  A0A0H2V7Q6  yniC  222 aa Hypothetical protein yniC n.s. ●●○○○ -1.16 -1.16320228278453
Escherichia coli CFT073  c0541  AAN79019.1  P0ABJ4  cyoC  204 aa Cytochrome O ubiquinol oxidase subunit III n.s. ●●○○○ -1.16 -1.1608669425138
Escherichia coli CFT073  c2693  AAN81149.1  Q8FFU1  yeiH  349 aa Hypothetical protein yeiH n.s. ●●○○○ -1.16 -1.16006569854906
Escherichia coli CFT073  c1132  AAN79600.1  A0A0H2V6R0  torC  406 aa Cytochrome c-type protein torC n.s. ●●○○○ -1.16 -1.16006569854905
Escherichia coli CFT073  c4026  AAN82466.1  P0ABT6  dusB  321 aa Hypothetical protein yhdG n.s. ●●○○○ -1.16 -1.15945317419814
Escherichia coli CFT073  c1373  AAN79843.1  P69787  ptsG  477 aa PTS system, glucose-specific IIBC component n.s. ●●○○○ -1.16 -1.15932704563225
Escherichia coli CFT073  c3766  AAN82210.1  A0A0H2VB73  245 aa Hypothetical protein n.s. ●●○○○ -1.16 -1.15894108614522
Escherichia coli CFT073  c2695  AAN81151.1  A0A0H2V8Y5  yeiI  362 aa Hypothetical sugar kinase yeiI n.s. ●●○○○ -1.16 -1.15864392525341
Escherichia coli CFT073  c2772  AAN81226.1  A0A0H2V930  yfaA  578 aa Hypothetical protein yfaA n.s. ●●○○○ -1.16 -1.15705047651554
Escherichia coli CFT073  c1519  AAN79988.1  A0A0H2V7M8  380 aa Prophage lambda integrase n.s. ●●○○○ -1.15 -1.15405796285622
Escherichia coli CFT073  c0959  AAN79432.1  A0A0H2V5K7  142 aa Putative Regulatory protein n.s. ●●○○○ -1.15 -1.14919660710045
Escherichia coli CFT073  c2104  AAN80564.1  A0A0H2V9Z9  nlpC  154 aa Probable lipoprotein nlpC precursor n.s. ●●○○○ -1.15 -1.14607241186561
Escherichia coli CFT073  c0883  AAN79356.1  Q8FJN1  dinG  716 aa Probable ATP-dependent helicase dinG n.s. ●●○○○ -1.15 -1.14607241186561
Escherichia coli CFT073  c2991  AAN81441.1  A0A0H2V9F2  ypfG  347 aa Hypothetical protein ypfG precursor n.s. ●●○○○ -1.15 -1.14589694631338
Escherichia coli CFT073  c0390  AAN78871.1  Q8FKM3  proA  417 aa Gamma-glutamyl phosphate reductase n.s. ●●○○○ -1.15 -1.14558107398372
Escherichia coli CFT073  c2724  AAN81178.1  Q8FFR9  yejK  335 aa 37 kDa nucleoid-associated protein n.s. ●●○○○ -1.14 -1.14494919684305
Escherichia coli CFT073  c1955  AAN80412.1  A0A0H2V7E4  481 aa 6-phospho-beta-glucosidase bglA n.s. ●●○○○ -1.14 -1.14481004419507
Escherichia coli CFT073  c1031  AAN79503.1  A0A0H2V6J8  dmsA  814 aa Anaerobic dimethyl sulfoxide reductase chain A precursor n.s. ●●○○○ -1.14 -1.14456026153895
Escherichia coli CFT073  c1863  AAN80326.1  A0A0H2V7A5  ydcR  468 aa Hypothetical protein ydcR n.s. ●●○○○ -1.14 -1.14424363686889
Escherichia coli CFT073  c0654  AAN79129.1  A0A0H2V749  nfrA  997 aa Bacteriophage N4 adsorption protein A precursor n.s. ●●○○○ -1.14 -1.14375930155224
Escherichia coli CFT073  c2057  AAN80517.1  Q8FH68  mdtK  457 aa Multidrug resistance protein norM n.s. ●●○○○ -1.14 -1.14239626859241
Escherichia coli CFT073  c2148  AAN80607.1  Q8FGZ9  astC  406 aa Succinylornithine transaminase n.s. ●●○○○ -1.14 -1.14115421932846
Escherichia coli CFT073  c2833  AAN81287.1  A0A0H2VBH3  yfbS  610 aa Hypothetical protein yfbS n.s. ●●○○○ -1.14 -1.14115421932845
Escherichia coli CFT073  c3156  AAN81608.1  A0A0H2VC57  261 aa Putative tail fiber component K of prophage n.s. ●●○○○ -1.14 -1.14001773020272
Escherichia coli CFT073  c0860  AAN79333.1  Q8FJP8  uvrB  673 aa Excinuclease ABC subunit B n.s. ●●○○○ -1.14 -1.1397833314618
Escherichia coli CFT073  c3759  AAN82203.1  A0A0H2VCH9  51 aa Hypothetical protein n.s. ●●○○○ -1.14 -1.13873591136213
Escherichia coli CFT073  c2977  AAN81427.1  A0A0H2VAV0  eutH  408 aa Ethanolamine utilization protein eutH n.s. ●●○○○ -1.14 -1.13873591136213
Escherichia coli CFT073  c0912  AAN79385.1  A0A0H2V5H3  moeA  411 aa Molybdopterin biosynthesis protein moeA n.s. ●●○○○ -1.14 -1.13640151814694
Escherichia coli CFT073  c2426  AAN80885.1  A0A0H2V8B3  709 aa Putative peptide synthetase n.s. ●●○○○ -1.13 -1.13128560723202
Escherichia coli CFT073  c0516  AAN78994.1  P0A848  tgt  375 aa Queuine tRNA-ribosyltransferase n.s. ●●○○○ -1.13 -1.12946299522562
Escherichia coli CFT073  c2899  AAN81349.1  A0A0H2V996  dsdC  317 aa D-serine deaminase activator n.s. ●●○○○ -1.13 -1.12857817920128
Escherichia coli CFT073  c0792  AAN79265.1  Q8FJU6  pxpA  244 aa Protein ybgL n.s. ●●○○○ -1.13 -1.12808357225728
Escherichia coli CFT073  c2379  AAN80838.1  A0A0H2VAJ2  vsr  156 aa Very short patch repair protein n.s. ●●○○○ -1.13 -1.12514535489462
Escherichia coli CFT073  c1066  AAN79534.1  Q8FJA2  mukB  1486 aa Cell division protein mukB n.s. ●●○○○ -1.12 -1.12447585153351
Escherichia coli CFT073  c1137  AAN79605.1  A0A0H2V5U5  agp  318 aa Glucose-1-phosphatase precursor n.s. ●●○○○ -1.12 -1.12397856721444
Escherichia coli CFT073  c2770  AAN81224.1  A0A0H2V973  1509 aa Putative membrane protein n.s. ●●○○○ -1.12 -1.11908348980836
Escherichia coli CFT073  c2419  AAN80878.1  A0A0H2V8D1  434 aa Putative anthranilate synthase n.s. ●●○○○ -1.12 -1.11866738127069
Escherichia coli CFT073  c1252  AAN79709.1  A0A0H2V660  iroD  409 aa Ferric enterochelin esterase n.s. ●●○○○ -1.12 -1.11773526800572
Escherichia coli CFT073  c2736  AAN81190.1  P0ABM2  ccmC  253 aa Heme exporter protein C n.s. ●●○○○ -1.12 -1.11649806720567
Escherichia coli CFT073  c0690  AAN79165.1  A0A0H2V775  406 aa Hypothetical protein ybdN n.s. ●●○○○ -1.12 -1.11631330962151
Escherichia coli CFT073  c0613  AAN79090.1  A0A0H2V5L2  ybbN  296 aa Hypothetical protein ybbN n.s. ●●○○○ -1.12 -1.11539650214133
Escherichia coli CFT073  c2925  AAN81375.1  Q8FFD5  fryC  415 aa Putative PTS system IIC component ypdG n.s. ●●○○○ -1.11 -1.11440942696561
Escherichia coli CFT073  c3690  AAN82138.1  A0A0H2VAT0  kpsC  675 aa KpsC protein n.s. ●●○○○ -1.11 -1.10947512679819
Escherichia coli CFT073  c0484  AAN78962.1  P0AAP8  yaiY  102 aa Hypothetical protein yaiY n.s. ●●○○○ -1.11 -1.10542369513157
Escherichia coli CFT073  c3515  AAN81963.1  A0A0H2VCT8  cmtA  462 aa PTS system, mannitol (Cryptic)-specific IIBC component n.s. ●●○○○ -1.1 -1.10265851683685
Escherichia coli CFT073  c1884  AAN80344.1  A0A0H2V7C0  246 aa Hypothetical protein n.s. ●●○○○ -1.1 -1.09951705953873
Escherichia coli CFT073  c0930  AAN79403.1  A0A0H2V5K1  ybjJ  423 aa Hypothetical protein ybjJ n.s. ●●○○○ -1.1 -1.09729692813246
Escherichia coli CFT073  c1387  AAN79857.1  A0A0H2V6D2  ycfS  377 aa Hypothetical protein ycfS precursor n.s. ●●○○○ -1.1 -1.09724675978245
Escherichia coli CFT073  c3086  AAN81535.1  A0A0H2V9S8  yfhL  86 aa Putative ferredoxin-like protein yfhL n.s. ●●○○○ -1.1 -1.09716159751239
Escherichia coli CFT073  c2928  AAN81378.1  Q8FFD3  yfeO  418 aa Hypothetical protein yfeO n.s. ●●○○○ -1.1 -1.09640209201748
Escherichia coli CFT073  c3401  AAN81846.1  A0A0H2VCL0  178 aa Hypothetical protein n.s. ●●○○○ -1.1 -1.09640209201746
Escherichia coli CFT073  c3066  AAN81516.1  A0A0H2V9L2  yphB  290 aa Hypothetical protein yphB n.s. ●●○○○ -1.09 -1.0934841980306
Escherichia coli CFT073  c2709  AAN81163.1  A0A0H2V932  yeiQ  491 aa Hypothetical oxidoreductase yeiQ n.s. ●●○○○ -1.09 -1.09217401112304
Escherichia coli CFT073  c0976  AAN79449.1  A0A0H2V7S0  947 aa Hypothetical protein n.s. ●●○○○ -1.09 -1.08943780737233
Escherichia coli CFT073  c0836  AAN79309.1  A0A0H2V7F9  modF  494 aa Putative molybdenum transport ATP-binding protein modF n.s. ●●○○○ -1.09 -1.08734433007684
Escherichia coli CFT073  c2327  AAN80786.1  P66797  uvrY  218 aa UvrY protein n.s. ●●○○○ -1.08 -1.08266400363805
Escherichia coli CFT073  c1280  AAN79754.1  A0A0H2V695  181 aa Hypothetical protein yafX n.s. ●●○○○ -1.08 -1.08208372155016
Escherichia coli CFT073  c1281  AAN79755.1  A0A0H2V897  319 aa Hypothetical protein n.s. ●●○○○ -1.08 -1.08208372155016
Escherichia coli CFT073  c0498  AAN78976.1  A0A0H2V4S9  aroM  225 aa AroM protein n.s. ●●○○○ -1.08 -1.07666477373089
Escherichia coli CFT073  c0502  AAN78980.1  Q8FKD5  rdgC  327 aa Recombination associated protein rdgC n.s. ●●○○○ -1.08 -1.07557329407728
Escherichia coli CFT073  c2551  AAN81006.1  Q8FG49  hisA  246 aa 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase n.s. ●●○○○ -1.07 -1.07430612326131
Escherichia coli CFT073  c0814  AAN79287.1  P0AAV1  ybgE  97 aa Protein ybgE n.s. ●●○○○ -1.07 -1.07368925180152
Escherichia coli CFT073  c1822  AAN80286.1  A0A0H2V9G6  ompN  377 aa Outer membrane protein N precursor n.s. ●●○○○ -1.07 -1.07239676759192
Escherichia coli CFT073  c2619  AAN81075.1  P69813  gatA  150 aa PTS system, galactitol-specific IIA component n.s. ●●○○○ -1.07 -1.07132656619282
Escherichia coli CFT073  c2533  AAN80987.1  A0A0H2VAX6  yeeW  64 aa Hypothetical protein yeeW n.s. ●●○○○ -1.07 -1.07076077066233
Escherichia coli CFT073  c2913  AAN81363.1  A0A0H2V9A3  45 aa Hypothetical protein n.s. ●●○○○ -1.07 -1.07029650446128
Escherichia coli CFT073  c2303  AAN80762.1  A0A0H2V832  cheA  672 aa Chemotaxis protein cheA n.s. ●●○○○ -1.07 -1.06863756199174
Escherichia coli CFT073  c1888  AAN80348.1  A0A0H2V9J9  801 aa Conserved hypothetical protein n.s. ●●○○○ -1.06 -1.06257438899683
Escherichia coli CFT073  c1466  AAN79935.1  A0A0H2V6G6  1230 aa Putative tail component of prophage n.s. ●●○○○ -1.06 -1.06165525442572
Escherichia coli CFT073  c2147  AAN80606.1  Q8FH00  astA  315 aa Arginine N-succinyltransferase n.s. ●●○○○ -1.06 -1.0605704012884
Escherichia coli CFT073  c0992  AAN79465.1  Q8FJE7  rlmC  375 aa Hypothetical RNA methyltransferase ybjF n.s. ●●○○○ -1.06 -1.0591158617756
Escherichia coli CFT073  c3441  AAN81886.1  A0A0H2VA72  yqeF  394 aa Probable acetyl-CoA acetyltransferase n.s. ●●○○○ -1.06 -1.05531804384804
Escherichia coli CFT073  c2264  AAN80721.1  A0A0H2VAA0  edd  625 aa Phosphogluconate dehydratase n.s. ●●○○○ -1.05 -1.0544822366815
Escherichia coli CFT073  c2214  AAN80673.1  A0A0H2VA71  yoaC  119 aa Hypothetical protein yoaC n.s. ●●○○○ -1.05 -1.05345716878431
Escherichia coli CFT073  c2477  AAN80936.1  Q8FGA5  cobT  359 aa Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase n.s. ●●○○○ -1.05 -1.05074582043402
Escherichia coli CFT073  c0655  AAN79130.1  A0A0H2V519  nfrB  720 aa Bacteriophage N4 adsorption protein B n.s. ●●○○○ -1.05 -1.04786144406431
Escherichia coli CFT073  c1445  AAN79914.1  A0A0H2V7G5  642 aa Putative DNA packaging protein of prophage; terminase large subunit n.s. ●●○○○ -1.05 -1.04719529562061
Escherichia coli CFT073  c1397  AAN79866.1  A0A0H2V6D6  ymfA  167 aa Hypothetical protein ymfA n.s. ●●○○○ -1.04 -1.0444647004189
Escherichia coli CFT073  c1901  AAN80361.1  A0A0H2V7A7  narU  462 aa Nitrite extrusion protein 2 n.s. ●●○○○ -1.04 -1.04368105298152
Escherichia coli CFT073  c2997  AAN81447.1  A0A0H2V9F8  acrD  1037 aa Probable aminoglycoside efflux pump n.s. ●●○○○ -1.04 -1.04115329421695
Escherichia coli CFT073  c1994  AAN80454.1  P0AB68  pntB  462 aa NAD(P) transhydrogenase subunit beta n.s. ●●○○○ -1.04 -1.03962621674969
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