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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2870  CBW18968.1  A0A0H3NL63  spaO  303 aa surface presentation of antigens protein (associated with type III secretion and virulence) n.s. ●●●○○ -2.83 -2.830449879937
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3623  CBW19716.1  A0A0H3NIY8  yiaH  331 aa hypothetical membrane protein n.s. ●●●○○ -2.83 -2.82727801377362
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3645  CBW19738.1  A0A0H3NMW4  aldB  512 aa aldehyde dehydrogenase B n.s. ●●●○○ -2.82 -2.81720843893088
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3157  CBW19256.1  A0A0H3NM24  cpdA  275 aa cyclic 3',5'-adenosine monophosphate phosphodiesterase n.s. ●●●○○ -2.81 -2.8064733138879
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0098  CBW16200.1  A0A0H3NH57  polB  783 aa DNA polymerase II n.s. ●●●○○ -2.79 -2.79139876190089
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4300  CBW20386.1  A0A0H3NIS0  nsrR  141 aa nitric oxide sensitive transcriptional repressor n.s. ●●●○○ -2.79 -2.79128790910563
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3372  CBW19467.1  A0A0H3NMD2  dprA  374 aa encodes cytoplasmic proteins involved in competence n.s. ●●●○○ -2.78 -2.78435263181234
Serratia marcescens Strain UMH9  BVG96_00180  ASL96123.1  283 aa bis(5'-nucleosyl)-tetraphosphatase (symmetrical) n.s. ●●●○○ -2.78 -2.77515017309945
Escherichia coli CFT073  c1856  AAN80319.1  A0A0H2V7H3  ydcL  222 aa Hypothetical lipoprotein ydcL precursor n.s. ●●●○○ -2.77 -2.76535015900051
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3956  CBW20046.1  A0A0H3NUP5  244 aa conserved hypothetical protein n.s. ●●●○○ -2.76 -2.76109939153862
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3713  AIK82268.1  225 aa ribulose-phosphate 3-epimerase n.s. ●●●○○ -2.76 -2.75930914514378
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1680  CBW17775.1  A0A0H3NLV7  adh  892 aa alcohol dehydrogenase n.s. ●●●○○ -2.75 -2.74751336238349
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2407  CBW18509.1  A0A0H3NK25  cysP  338 aa thiosulphate-binding protein precursor n.s. ●●●○○ -2.74 -2.74228206033234
Escherichia coli CFT073  c2055  AAN80515.1  P0A9H8  cfa  382 aa Cyclopropane-fatty-acyl-phospholipid synthase n.s. ●●●○○ -2.72 -2.72458118763976
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4509  CBW20598.1  A0A0H3NLE0  slt  657 aa lytic murein transglycosylase n.s. ●●●○○ -2.72 -2.72114232645233
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4425  CBW20513.1  A0A0H3NPX0  1213 aa hypothetical ATPase n.s. ●●●○○ -2.7 -2.69922202197679
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1751  CBW17846.1  A0A0H3NCF9  yoaB  114 aa conserved hypothetical protein n.s. ●●●○○ -2.7 -2.69770943258166
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4049  CBW20138.1  A0A0H3NK50  metB  386 aa cystathionine gamma-synthase n.s. ●●●○○ -2.68 -2.67641538289442
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2875  CBW18973.1  A0A0H3NL68  invA  685 aa secretory apparatus of type III secretion system n.s. ●●●○○ -2.67 -2.67169516303568
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3477  CBW19572.1  A0A0H3NT25  comF  227 aa competence gene-DNA binding and transport n.s. ●●●○○ -2.67 -2.66691288820255
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3088  CBW19187.1  A0A0H3NFX1  nupG  418 aa nucleoside permease nupg (nucleoside-transport system protein) n.s. ●●●○○ -2.66 -2.66235477990109
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4198  CBW20285.1  A0A0H3NKH1  siiF  688 aa hypothetical type-1 secretion protein n.s. ●●●○○ -2.66 -2.66069840660876
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3099  CBW19198.1  A0A0H3NRT3  185 aa hypothetical protein n.s. ●●●○○ -2.66 -2.65778435880179
Escherichia coli CFT073  c1606  AAN80074.1  A0A0H2V936  ycgF  429 aa Hypothetical protein ycgF n.s. ●●●○○ -2.66 -2.65752650051482
Escherichia coli CFT073  c2209  AAN80668.1  P69452  fadD  583 aa Long-chain-fatty-acid--CoA ligase n.s. ●●●○○ -2.65 -2.64741134434246
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1220  CBW17315.2  A0A0H3NKH8  yeaG  594 aa conserved hypothetical protein n.s. ●●●○○ -2.64 -2.64250712935387
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3581  CBW19675.1  A0A0H3NH78  yhjL  1180 aa hypothetical polysaccharide biosynthesis protein subunit C n.s. ●●●○○ -2.63 -2.63154554043533
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4012  CBW20101.1  A0A0H3NUZ6  sbp  329 aa periplasmic sulphate binding protein n.s. ●●●○○ -2.62 -2.62118235704461
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2120  CBW18216.1  A0A0H3NNE0  yegU  334 aa hypothetical hydrolase n.s. ●●●○○ -2.62 -2.61679865261212
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4186  CBW20273.1  A0A0H3NIT4  yjbQ  138 aa conserved hypothetical protein n.s. ●●●○○ -2.61 -2.60959879189166
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3245  CBW19341.1  A0A0H3NM68  yhbS  167 aa hypothetical acetyltransferase n.s. ●●●○○ -2.61 -2.60677832155917
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1153  CBW17249.1  A0A0H3NKB1  mfd  1148 aa transcription-repair coupling factor (TrcF) n.s. ●●●○○ -2.6 -2.60221552500197
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2346  CBW18448.1  A0A0H3NDV5  218 aa conserved hypothetical protein n.s. ●●●○○ -2.6 -2.59802081243243
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0036  CBW16137.1  A0A0H3N7C5  497 aa hypothetical secreted sulfatase n.s. ●●●○○ -2.59 -2.59454151250082
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4124  CBW20212.1  A0A0H3NIP3  yjbB  518 aa hypothetical membrane protein n.s. ●●●○○ -2.59 -2.59400997065056
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0052  CBW16153.1  A0A0H3NCJ8  rihC  306 aa hypothetical nucleoside hydrolase (IUNH family) n.s. ●●●○○ -2.59 -2.59252016184654
Escherichia coli CFT073  c1162  AAN79630.1  A0A0H2V5Y9  ycdR  672 aa Hypothetical lipoprotein ycdR precursor n.s. ●●●○○ -2.59 -2.59222274006338
Escherichia coli CFT073  c2613  AAN81069.1  A0A0H2V8Y3  yegR  110 aa Hypothetical protein yegR n.s. ●●●○○ -2.59 -2.58567957610021
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0079  CBW16180.1  A0A0H3N7G1  fixX  95 aa ferredoxin like protein FixX n.s. ●●●○○ -2.59 -2.58508199756836
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0037  CBW16138.1  A0A0H3NCI6  396 aa possible sulfatase regulatory protein n.s. ●●●○○ -2.58 -2.57982466343332
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1779  CBW17873.1  A0A0H3NDS7  yebU  479 aa conserved hypothetical protein n.s. ●●●○○ -2.58 -2.5788888614213
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1604  CBW17699.1  A0A0H3NC03  196 aa hypothetical transcriptional regulator n.s. ●●●○○ -2.55 -2.5479019532191
Escherichia coli CFT073  c2001  AAN80461.1  A0A0H2V7H2  rstB  433 aa Sensor protein rstB n.s. ●●●○○ -2.53 -2.52782180424617
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3847  CBW19938.1  A0A0H3NJH6  kup  622 aa membrane transport protein n.s. ●●●○○ -2.52 -2.5189575118126
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3951  CBW20041.1  A0A0H3NUN6  hemN  457 aa oxygen-independent coproporphyrinogen III oxidase n.s. ●●●○○ -2.52 -2.51827801905831
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4845  AIK83372.1  184 aa NADH:ubiquinone oxidoreductase, membrane subunitJ n.s. ●●●○○ -2.52 -2.51697339993924
Serratia marcescens Strain UMH9  BVG96_13260  ASL98535.1  291 aa LysR family transcriptional regulator n.s. ●●●○○ -2.51 -2.51485440210932
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0584  CBW16684.1  A0A0H3NAG6  entE  536 aa 2,3-dihydroxybenzoate-AMP ligase n.s. ●●●○○ -2.51 -2.51467538142213
Escherichia coli CFT073  c1025  AAN79497.1  A0A0H2V5S0  trxB  361 aa Thioredoxin reductase n.s. ●●●○○ -2.51 -2.51451736258756
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1524  CBW17618.1  A0A0H3NLF1  srfA  439 aa virulence protein n.s. ●●●○○ -2.51 -2.50951067853965
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2998  CBW19097.1  A0A0H3NFQ2  287 aa possible regulatory protein n.s. ●●●○○ -2.51 -2.50901278770189
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2554  CBW18655.1  A0A0H3NEF4  215 aa predicted bacteriophage protein n.s. ●●●○○ -2.51 -2.50755352324274
Escherichia coli CFT073  c1837  AAN80300.1  A0A0H2V8D6  ynbD  463 aa Hypothetical protein ynbD n.s. ●●●○○ -2.51 -2.50627480809788
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3822  CBW19913.1  A0A0H3NJE0  pstA  296 aa phosphate transport system permease protein n.s. ●●●○○ -2.51 -2.50515520180614
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1313  CBW17409.1  A0A0H3NG63  orf48  447 aa hypothetical amino acid permease n.s. ●●●○○ -2.5 -2.50095528472294
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4139  CBW20227.1  A0A0H3NP44  515 aa hypothetical membrane protein n.s. ●●●○○ -2.5 -2.49523712498494
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0197  CBW16299.1  A0A0H3N859  stfC  885 aa outer membrane usher protein stfc (hypothetical fimbrial outer membrane usher) n.s. ●●●○○ -2.49 -2.49454878372446
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0836  CBW16933.1  A0A0H3NJE2  141 aa hypothetical inner membrane protein n.s. ●●●○○ -2.48 -2.47891430681728
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0010  CBW16111.1  A0A0H3N8R2  htgA  237 aa conserved hypothetical protein n.s. ●●●○○ -2.48 -2.47829282862742
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4209  CBW20296.1  A0A0H3NII4  actP  549 aa Sodium:solute symporter family protein n.s. ●●●○○ -2.48 -2.47734935375952
Escherichia coli CFT073  c2569  AAN81024.1  A0A0H2V8V0  wcaL  406 aa Putative colanic acid biosynthesis glycosyl transferase wcaL n.s. ●●●○○ -2.46 -2.46436801774304
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3461  CBW19556.1  A0A0H3NT07  nudE  187 aa hypothetical NUDIX hydrolase n.s. ●●●○○ -2.45 -2.45356328447624
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3672  CBW19765.1  A0A0H3NTP6  yigQ  320 aa hypothetical exported protein n.s. ●●●○○ -2.45 -2.44892116273091
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3906  CBW19997.1  A0A0H3NJN5  corA  316 aa magnesium and cobalt transport protein n.s. ●●●○○ -2.45 -2.44591140750558
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2057  CBW18153.1  A0A0H3ND19  udg  388 aa UDP-glucose 6-dehydrogenase n.s. ●●●○○ -2.45 -2.44562245465105
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0556  CBW16656.1  A0A0H3NDX9  pheP  464 aa phenylalanine-specific permease n.s. ●●●○○ -2.44 -2.44026532438316
Escherichia coli CFT073  c3027  AAN81477.1  A0A0H2V9L5  guaB  511 aa Inosine-5'-monophosphate dehydrogenase n.s. ●●●○○ -2.43 -2.43395156156867
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0600  CBW16700.1  A0A0H3N8T6  185 aa molybdopterin-containing oxidoreductase iron-sulfur subunit n.s. ●●●○○ -2.43 -2.43352262154005
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3793  CBW19884.1  A0A0H3NN73  dgoT  445 aa d-galactonate transporter n.s. ●●●○○ -2.43 -2.43331521194034
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4502  CBW20591.1  A0A0H3NJG9  229 aa hypothetical outer membrane protein n.s. ●●●○○ -2.42 -2.42333876023118
Escherichia coli CFT073  c1771  AAN80237.1  A0A0H2V884  sapA  547 aa Peptide transport periplasmic protein sapA precursor n.s. ●●●○○ -2.42 -2.42179015723186
Escherichia coli CFT073  c1997  AAN80457.1  P0AAE6  ydgI  469 aa Putative arginine/ornithine antiporter n.s. ●●●○○ -2.42 -2.42106857972361
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3116  CBW19215.1  A0A0H3NFY8  350 aa possible ABC-transport protein, periplasmic-binding component n.s. ●●●○○ -2.42 -2.42007577806987
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4074  CBW20162.1  A0A0H3NV41  oxyR  305 aa hydrogen peroxide-inducible regulon activator n.s. ●●●○○ -2.42 -2.41944135257136
Escherichia coli CFT073  c2393  AAN80852.1  A0A0H2V8B2  606 aa Hypothetical protein n.s. ●●●○○ -2.39 -2.39344171000984
Escherichia coli CFT073  c2448  AAN80907.1  A0A0H2V8L0  yeeO  546 aa Hypothetical protein yeeO n.s. ●●●○○ -2.38 -2.37790705841798
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3853  CBW19944.1  A0A0H3NHS9  rbsR  332 aa ribose operon repressor n.s. ●●●○○ -2.38 -2.37764817806673
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3246  AIK81807.1  731 aa primosomal protein N' n.s. ●●●○○ -2.37 -2.36620665107015
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2314  CBW18416.1  A0A0H3NP09  339 aa hypothetical transcriptional regulator n.s. ●●●○○ -2.36 -2.36297406214265
Escherichia coli CFT073  c1682  AAN80149.1  A0A0H2V759  narX  598 aa Nitrate/nitrite sensor protein narX n.s. ●●●○○ -2.36 -2.36008902725441
Escherichia coli CFT073  c1689  AAN80156.1  A0A0H2V6Z2  347 aa Hypothetical protein n.s. ●●●○○ -2.35 -2.35461648867093
Escherichia coli CFT073  c1051  AAN79521.1  A0A0H2V6K7  102 aa Hypothetical protein n.s. ●●●○○ -2.35 -2.34501254411669
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4430  CBW20518.1  A0A0H3NJ47  yjhP  543 aa conserved hypothetical protein n.s. ●●●○○ -2.34 -2.33906505925809
Serratia marcescens Strain UMH9  BVG96_15775  ASL98996.1  305 aa transcriptional regulator GcvA n.s. ●●●○○ -2.33 -2.33187056027298
Escherichia coli CFT073  c0867  AAN79340.1  A0A0H2V5E8  moaE  150 aa Molybdopterin converting factor subunit 2 n.s. ●●●○○ -2.33 -2.32893613116313
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4137  CBW20225.1  A0A0H3NKB6  371 aa hypothetical bacteriophage protein n.s. ●●●○○ -2.32 -2.31962411460118
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4378  CBW20466.1  A0A0H3NPS6  637 aa hypothetical BglB-family transcriptional antiterminator n.s. ●●●○○ -2.3 -2.30302447659622
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3216  CBW19314.1  A0A0H3NI54  tdcB  329 aa catabolic threonine dehydratase n.s. ●●●○○ -2.3 -2.29637076429484
Escherichia coli CFT073  c2798  AAN81252.1  Q8FFM0  arnD  296 aa Hypothetical protein yfbH n.s. ●●●○○ -2.3 -2.29513753167487
Escherichia coli CFT073  c3056  AAN81506.1  P0A6B8  iscS  412 aa Cysteine desulfurase n.s. ●●●○○ -2.29 -2.28737792178724
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3906  AIK82454.1  70 aa hypothetical protein n.s. ●●●○○ -2.28 -2.28135657136667
Escherichia coli CFT073  c1832  AAN80295.1  A0A0H2V8D0  ydbC  286 aa Hypothetical oxidoreductase ydbC n.s. ●●●○○ -2.28 -2.28097871181535
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1505  CBW17599.1  A0A0H3ND57  smvA  495 aa methyl viologen resistance protein SmvA n.s. ●●●○○ -2.28 -2.27956480213895
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0027  CBW16128.1  A0A0H3NCH7  bcfG  234 aa fimbrial chaperone n.s. ●●●○○ -2.28 -2.27936050590816
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1818  CBW17912.1  A0A0H3NCB2  eda  213 aa KHG/KDPG aldolase n.s. ●●●○○ -2.28 -2.27892752243752
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1008  CBW17104.1  A0A0H3NJX6  lonH  528 aa conserved hypothetical protein n.s. ●●●○○ -2.28 -2.2787890394523
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3617  CBW19710.1  A0A0H3NTI6  161 aa hypothetical acetyltransferase n.s. ●●●○○ -2.27 -2.27334614570975
Serratia marcescens Strain UMH9  BVG96_05425  ASL97086.1  438 aa paraquat-inducible protein A n.s. ●●●○○ -2.26 -2.26421275243483
Escherichia coli CFT073  c2243  AAN80702.1  A0A0H2V855  yebT  891 aa Hypothetical protein yebT n.s. ●●●○○ -2.26 -2.2626115525078
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0097  CBW16199.1  A0A0H3N7V6  hepA  968 aa probable ATP-dependent helicase HepA n.s. ●●●○○ -2.26 -2.26165111505808
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