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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli CFT073  c2094  AAN80554.1  A0A0H2V7N5  ydiR  312 aa Putative electron transfer flavoprotein subunit ydiR n.s. ●●●○○ -2.26 -2.2556127591194
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1302  AIK79925.1  47 aa hypothetical protein n.s. ●●●○○ -2.25 -2.25474770496481
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1862  CBW17956.1  E1WGG8  otsA  473 aa trehalose-6-phosphate synthase n.s. ●●●○○ -2.25 -2.25155324411673
Escherichia coli CFT073  c1598  AAN80066.1  A0A0H2V6S9  sitC  285 aa SitC protein n.s. ●●●○○ -2.25 -2.25082130147757
Serratia marcescens Strain UMH9  BVG96_04520  ASL96910.1  229 aa CMP-N-acetylneuraminic acid synthetase n.s. ●●●○○ -2.25 -2.25036479513278
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1408  CBW17503.1  A0A0H3NB60  ydgH  314 aa hypothetical exported protein n.s. ●●●○○ -2.25 -2.2475602829603
Escherichia coli CFT073  c1626  AAN80091.1  A0A0H2V6W9  ycgK  133 aa Protein ycgK precursor n.s. ●●●○○ -2.24 -2.2446064476398
Escherichia coli CFT073  c3043  AAN81493.1  A0A0H2V9F4  yfhM  1653 aa Hypothetical lipoprotein yfhM precursor n.s. ●●●○○ -2.24 -2.24220985307229
Serratia marcescens Strain UMH9  BVG96_10315  ASL97990.1  231 aa septum site-determining protein MinC n.s. ●●●○○ -2.24 -2.24196403500795
Serratia marcescens Strain UMH9  BVG96_20210  ASL99802.1  231 aa tRNA (guanosine(18)-2'-O)-methyltransferase TrmH n.s. ●●●○○ -2.24 -2.24190729801597
Escherichia coli CFT073  c1745  AAN80211.1  A0A0H2V9B9  acnA  891 aa Aconitate hydratase 1 n.s. ●●●○○ -2.24 -2.2408244543047
Escherichia coli CFT073  c1941  AAN80399.1  Q8FHF3  hipB  94 aa Protein hipB n.s. ●●●○○ -2.24 -2.23518173332348
Escherichia coli CFT073  c2044  AAN80504.1  A0A0H2V7M0  gloA  135 aa Lactoylglutathione lyase n.s. ●●●○○ -2.23 -2.23198148462411
Serratia marcescens Strain UMH9  BVG96_17910  ASL99384.1  182 aa hypothetical protein n.s. ●●●○○ -2.23 -2.23180724801714
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0501  CBW16601.1  A0A0H3NA62  ybbP  804 aa hypothetical membrane protein n.s. ●●●○○ -2.23 -2.2312592924317
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4069  CBW20157.1  A0A0H3NV38  ppc  883 aa phosphoenolpyruvate carboxylase n.s. ●●●○○ -2.23 -2.23085062084201
Escherichia coli CFT073  c1795  AAN80261.1  A0A0H2V8A7  tyrR  522 aa Transcriptional Regulatory protein tyrR n.s. ●●●○○ -2.23 -2.22736126053441
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3800  CBW19891.1  A0A0H3NU32  397 aa possible racemase n.s. ●●●○○ -2.23 -2.22513776584804
Escherichia coli CFT073  c2733  AAN81187.1  A0A0H2V909  ccmF  647 aa Cytochrome c-type biogenesis protein ccmF n.s. ●●●○○ -2.22 -2.22436998467892
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2863  CBW18961.1  E1WAC8  sipC  409 aa pathogenicity island 1 Type III secretion system effector protein-involved in bacterial entry by actin bundling and part of the Translocon n.s. ●●●○○ -2.22 -2.22289323127509
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1452  CBW17547.1  A0A0H3NL95  sotB  396 aa Probable sugar efflux transporter. n.s. ●●●○○ -2.22 -2.22173349180116
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4216  CBW20303.1  A0A0H3NIV3  nrfD  318 aa subunit of nitrite reductase complex n.s. ●●●○○ -2.22 -2.22071612871358
Escherichia coli CFT073  c1713  AAN80180.1  P0A6H9  clsA  486 aa Cardiolipin synthetase n.s. ●●●○○ -2.22 -2.22068675154077
Escherichia coli CFT073  c2605  AAN81061.1  P69229  baeR  240 aa Transcriptional Regulatory protein baeR n.s. ●●●○○ -2.22 -2.21726955041758
Escherichia coli CFT073  c2422  AAN80881.1  A0A0H2V8I8  600 aa Putative inner membrane ABC-transporter n.s. ●●●○○ -2.22 -2.21537232748913
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4435  CBW20523.1  A0A0H3NJ51  153 aa hypothetical exported protein n.s. ●●●○○ -2.22 -2.21536546973198
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3553  CBW19647.1  A0A0H3NH55  yhiN  398 aa hypothetical exported protein n.s. ●●●○○ -2.21 -2.21430122116153
Escherichia coli CFT073  c2203  AAN80662.1  A0A0H2V7W3  163 aa Hypothetical protein n.s. ●●●○○ -2.21 -2.20885166787138
Serratia marcescens Strain UMH9  BVG96_08350  ASL97625.1  572 aa peptidoglycan synthase n.s. ●●●○○ -2.21 -2.20877946767797
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2345  AIK80948.1  267 aa 4-nitrobenzaldehyde reductase (multifunctional) n.s. ●●●○○ -2.2 -2.20482835479528
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4485  AIK83028.1  352 aa protein RecA n.s. ●●●○○ -2.2 -2.20482835479528
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1484  CBW17579.1  A0A0H3ND45  488 aa conserved hypothetical protein n.s. ●●●○○ -2.2 -2.20335413637948
Serratia marcescens Strain UMH9  BVG96_13365  ASL98554.1  400 aa acetate kinase n.s. ●●●○○ -2.2 -2.2022007448587
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3593  CBW19687.1  A0A0H3NMT3  dppD  327 aa dipeptide transport ATP-binding protein DppD n.s. ●●●○○ -2.2 -2.20161692919677
Escherichia coli CFT073  c2022  AAN80482.1  Q8FH94  rsxD  352 aa Electron transport complex protein rnfD n.s. ●●●○○ -2.2 -2.20080983760601
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1743  CBW17838.1  A0A0H3NC49  minD  270 aa septum site determining protein n.s. ●●●○○ -2.2 -2.19958157010334
Escherichia coli CFT073  c1968  AAN80428.1  A0A0H2V7F2  486 aa Hypothetical oxidoreductase ydfI n.s. ●●●○○ -2.19 -2.19261178522087
Escherichia coli CFT073  c2717  AAN81171.1  A0A0H2V901  yejF  529 aa Hypothetical ABC transporter ATP-binding protein yejF n.s. ●●●○○ -2.19 -2.19221422895652
Escherichia coli CFT073  c2455  AAN80914.1  A0A0H2V8G4  1120 aa Putative peptide synthetase n.s. ●●●○○ -2.19 -2.19120195186059
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0539  CBW16638.1  A0A0H3NDW6  fimD  870 aa outer membrane usher protein FimD precursor n.s. ●●●○○ -2.19 -2.18996576079102
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3031  CBW19130.1  A0A0H3NFT0  gcvT  364 aa Aminomethyltransferase n.s. ●●●○○ -2.19 -2.18801897433125
Escherichia coli CFT073  c2076  AAN80536.1  A0A0H2V7L8  ynhC  423 aa SufD protein n.s. ●●●○○ -2.18 -2.17732186152964
Escherichia coli CFT073  c1849  AAN80312.1  Q8CW34  mdoD  551 aa Protein ydcG precursor n.s. ●●●○○ -2.17 -2.17182195962091
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4103  CBW20191.1  A0A0H3NP05  thiC  631 aa thiamine biosynthesis protein n.s. ●●●○○ -2.17 -2.16796134466178
Escherichia coli CFT073  c1341  AAN79812.1  A0A0H2V688  flgA  219 aa Flagella basal body P-ring formation protein flgA precursor n.s. ●●●○○ -2.17 -2.16677026981113
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2914  CBW19013.1  A0A0H3NH53  cysD  302 aa ATP sulfurylase (ATP:sulfate adenyltransferase) n.s. ●●●○○ -2.17 -2.16654507161281
Escherichia coli CFT073  c1205  AAN79667.1  A0A0H2V5Z4  908 aa Hypothetical protein n.s. ●●●○○ -2.17 -2.16634670902292
Escherichia coli CFT073  c2469  AAN80928.1  A0A0H2VAT2  1352 aa Putative polyketide synthase n.s. ●●●○○ -2.16 -2.16282728673657
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0487  CBW16587.1  A0A0H3N8I8  ushA  550 aa UDP-sugar hydrolase n.s. ●●●○○ -2.16 -2.1627173369392
Escherichia coli CFT073  c1867  AAN80330.1  A0A0H2V9J0  ydcV  214 aa Hypothetical ABC transporter permease protein ydcV n.s. ●●●○○ -2.16 -2.15856732585429
Escherichia coli CFT073  c1934  AAN80392.1  A0A0H2V7M2  883 aa Outer membrane usher protein fimD precursor n.s. ●●●○○ -2.16 -2.15665133711817
Serratia marcescens Strain UMH9  BVG96_02620  ASL96561.1  379 aa N-acetylglucosamine-6-phosphate deacetylase n.s. ●●●○○ -2.15 -2.15277008756197
Streptococcus pyogenes M1 5448  SP5448_04665  WP_002984437.1  232 aa ABC transporter ATP-binding protein n.s. ●●●○○ -2.15 -2.14684095849772
Serratia marcescens Strain UMH9  BVG96_06525  ASL97289.1  363 aa GTP-binding protein YchF n.s. ●●●○○ -2.14 -2.1443494712319
Serratia marcescens Strain UMH9  BVG96_06080  ASL97208.1  173 aa hypothetical protein n.s. ●●●○○ -2.14 -2.14228380125806
Serratia marcescens Strain UMH9  BVG96_17560  ASL99317.1  226 aa DedA family protein n.s. ●●●○○ -2.14 -2.13934374696903
Escherichia coli CFT073  c2453  AAN80912.1  A0A0H2V8L4  819 aa Putative polyketide synthase n.s. ●●●○○ -2.14 -2.13906230530949
Escherichia coli CFT073  c2818  AAN81272.1  A0A0H2V953  nuoM  509 aa NADH dehydrogenase I chain M n.s. ●●●○○ -2.13 -2.13182253349144
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1114  CBW17210.1  A0A0H3NC32  flgE  403 aa flagellar hook protein FlgE n.s. ●●●○○ -2.13 -2.13072557900303
Vibrio parahaemolyticus RIMD 2210633  VPA_0076  BAC61419.1  Q87K22  265 aa putative regulator n.s. ●●●○○ -2.13 -2.13008648928075
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3355  CBW19450.1  A0A0H3NIB9  panF  483 aa sodium/pantothenate symporter (pantothenate permease) n.s. ●●●○○ -2.13 -2.12895820146045
Streptococcus pyogenes M1 5448  SP5448_01290  WP_002986055.1  312 aa HD domain-containing protein n.s. ●●●○○ -2.13 -2.1256915555403
Escherichia coli CFT073  c2461  AAN80920.1  A0A0H2V9S6  1603 aa Hypothetical protein n.s. ●●●○○ -2.12 -2.12058477498486
Escherichia coli CFT073  c1765  AAN80231.1  A0A0H2V7A8  457 aa Partial Putative outer membrane channel protein n.s. ●●●○○ -2.12 -2.11866878624874
Escherichia coli CFT073  c1977  AAN80437.1  A0A0H2V7F7  ynfE  808 aa Putative dimethyl sulfoxide reductase chain ynfE precursor n.s. ●●●○○ -2.12 -2.11769209160895
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2742  CBW18842.1  A0A0H3NGN6  513 aa PTS system, glucose-specific IIbc component n.s. ●●●○○ -2.12 -2.11687278797017
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1533  CBW17628.1  A0A0H3NLF7  yncJ  76 aa conserved hypothetical protein n.s. ●●●○○ -2.11 -2.11499001936034
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4293  CBW20379.1  A0A0H3NVU8  mutL  618 aa DNA mismatch repair protein n.s. ●●●○○ -2.11 -2.11477275767028
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4318  CBW20404.1  A0A0H3NJ36  ptxA  154 aa probable sugar phosphotransferase n.s. ●●●○○ -2.11 -2.11440551933488
Streptococcus pyogenes M1 5448  SP5448_06065  WP_002994010.1  262 aa hypothetical protein n.s. ●●●○○ -2.11 -2.11319418106546
Escherichia coli CFT073  c2202  AAN80661.1  P64497  yoaG  60 aa Hypothetical protein yoaG n.s. ●●●○○ -2.11 -2.11253908347272
Streptococcus pyogenes M1 5448  SP5448_08600  WP_010922697.1  249 aa 16S rRNA (uracil(1498)-N(3))-methyltransferase n.s. ●●●○○ -2.11 -2.11031017157126
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0965  CBW17061.1  A0A0H3NJU0  gtgA  228 aa hypothetical bacteriophage encoded virulence protein n.s. ●●●○○ -2.11 -2.10716393590449
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1772  AIK80392.1  347 aa quinolinate synthetase complex, A subunit n.s. ●●●○○ -2.11 -2.10595161076021
Escherichia coli CFT073  c1803  AAN80267.1  A0A0H2V8B1  mppA  544 aa Periplasmic murein peptide-binding protein precursor n.s. ●●●○○ -2.1 -2.10462899986717
Escherichia coli CFT073  c1978  AAN80438.1  A0A0H2V7P8  ynfF  808 aa Probable dimethyl sulfoxide reductase chain ynfF precursor n.s. ●●●○○ -2.1 -2.10429590110043
Vibrio parahaemolyticus RIMD 2210633  VPA_0911  BAC62254.1  Q87HQ2  46 aa hypothetical protein n.s. ●●●○○ -2.1 -2.10326499598882
Vibrio parahaemolyticus RIMD 2210633  VPA_1072  BAC62415.1  Q87H93  151 aa hypothetical protein n.s. ●●●○○ -2.1 -2.10220317740444
Escherichia coli CFT073  c1756  AAN80222.1  A0A0H2V722  yciR  661 aa Hypothetical protein yciR n.s. ●●●○○ -2.1 -2.10135139439217
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3128  CBW19227.1  A0A0H3NFZ9  171 aa exported protein n.s. ●●●○○ -2.1 -2.09694735716533
Escherichia coli CFT073  c2067  AAN80527.1  A0A0H2V7L4  ydhV  728 aa Hypothetical protein ydhV n.s. ●●●○○ -2.1 -2.09554931526449
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3336  CBW19432.1  A0A0H3NMB4  yhcP  655 aa hypothetical membrane protein n.s. ●●●○○ -2.09 -2.08980045260019
Escherichia coli CFT073  c2021  AAN80481.1  Q8FH95  rsxC  742 aa Electron transport complex protein rnfC n.s. ●●●○○ -2.09 -2.08890007595829
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0552  CBW16652.1  A0A0H3N986  ykgC  441 aa probable pyridine nucleotide-disulfide oxidoreductase n.s. ●●●○○ -2.09 -2.08675893796015
Escherichia coli CFT073  c1338  AAN79809.1  A0A0H2V8C8  mviN  511 aa Virulence factor mviN homolog n.s. ●●●○○ -2.08 -2.0848916815806
Vibrio parahaemolyticus RIMD 2210633  VPA_1357  BAC62700.1  Q87GF9  1622 aa hypothetical protein n.s. ●●●○○ -2.08 -2.08328763157749
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2999  CBW19098.1  A0A0H3NRF3  160 aa conserved hypothetical protein n.s. ●●●○○ -2.08 -2.07888467589644
Streptococcus pyogenes M1 5448  SP5448_04630  WP_011054795.1  257 aa hypothetical protein n.s. ●●●○○ -2.08 -2.07666339413899
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3300  CBW19396.1  A0A0H3NGG7  arcB  778 aa aerobic respiration control sensor protein n.s. ●●●○○ -2.08 -2.07604218051055
Serratia marcescens Strain UMH9  BVG96_06065  ASL97205.1  1125 aa ribonuclease E n.s. ●●●○○ -2.07 -2.07337366124694
Escherichia coli CFT073  c1329  AAN79802.1  Q8FIR2  pyrC  348 aa Dihydroorotase n.s. ●●●○○ -2.07 -2.07313743768766
Serratia marcescens Strain UMH9  BVG96_06220  ASL97235.1  159 aa transcriptional regulator n.s. ●●●○○ -2.07 -2.07277107557229
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4358  CBW20445.1  A0A0H3NPQ1  srfJ  447 aa A virulence factor, a gylcoside hydrolase family enzyme n.s. ●●●○○ -2.07 -2.0721154872252
Streptococcus pyogenes M1 5448  SP5448_00620  WP_002986548.1  142 aa competence protein n.s. ●●●○○ -2.07 -2.07185671164867
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3174  CBW19273.1  A0A0H3NS28  glnE  947 aa adenyl-transferase n.s. ●●●○○ -2.07 -2.07061677218428
Escherichia coli CFT073  c1164  AAN79632.1  A0A0H2V5W1  ycdT  496 aa Hypothetical protein ycdT n.s. ●●●○○ -2.07 -2.07017974737405
Escherichia coli CFT073  c1392  AAN79861.1  Q8FIM7  lolD  233 aa Lipoprotein releasing system ATP-binding protein lolD n.s. ●●●○○ -2.07 -2.06851921529523
Escherichia coli CFT073  c1086  AAN79554.1  P0AFM0  pqiA  417 aa Paraquat-inducible protein A n.s. ●●●○○ -2.07 -2.06745213008825
Streptococcus pyogenes M1 5448  SP5448_02285  WP_002988718.1  185 aa DUF2815 family protein n.s. ●●●○○ -2.07 -2.06705002915835
Streptococcus pyogenes M1 5448  SP5448_04815  WP_010922362.1  134 aa Spx/MgsR family RNA polymerase-binding regulatory protein n.s. ●●●○○ -2.07 -2.06705002915835
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