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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli CFT073  c1379  AAN79849.1  Q8FIN3  thiK  274 aa Hypothetical protein ycfN n.s. ●●○○○ -1.94 -1.93751818740599
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1814  CBW17908.1  A0A0H3NHS7  yebE  219 aa conserved hypothetical protein n.s. ●●○○○ -1.94 -1.93655339171665
Vibrio parahaemolyticus RIMD 2210633  VPA_1622  BAC62965.1  Q87FQ6  57 aa hypothetical protein n.s. ●●○○○ -1.94 -1.93551408375276
Vibrio parahaemolyticus RIMD 2210633  VP_0505  BAC58768.1  Q87SB9  srmB  407 aa ATP-dependent RNA helicase SrmB n.s. ●●○○○ -1.93 -1.93410566331242
Vibrio parahaemolyticus RIMD 2210633  VP_0356  BAC58619.1  Q87SR6  470 aa pyruvate kinase I n.s. ●●○○○ -1.93 -1.93410566331242
Escherichia coli CFT073  c2284  AAN80741.1  Q8FGQ6  cmoA  247 aa Protein yecO n.s. ●●○○○ -1.93 -1.93257969394871
Escherichia coli CFT073  c1749  AAN80215.1  P0AB59  lapB  389 aa Hypothetical protein yciM precursor n.s. ●●○○○ -1.93 -1.93238785925746
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3778  CBW19868.1  A0A0H3NU09  yidR  408 aa hypothetical ATP/GTP-binding protein n.s. ●●○○○ -1.93 -1.93179452081084
Escherichia coli CFT073  c2848  AAN81302.1  A0A0H2V9B3  hisP  257 aa Histidine transport ATP-binding protein hisP n.s. ●●○○○ -1.93 -1.93075792151721
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3580  CBW19674.1  A0A0H3NIW1  yhjK  639 aa conserved hypothetical protein n.s. ●●○○○ -1.93 -1.9306569743378
Streptococcus pyogenes M1 5448  SP5448_01230  WP_010921876.1  220 aa DUF624 domain-containing protein n.s. ●●○○○ -1.93 -1.93054024643314
Vibrio parahaemolyticus RIMD 2210633  VP_2375  BAC60638.1  Q87M83  recC  1163 aa exodeoxyribonuclease V, 125 kDa subunit n.s. ●●○○○ -1.93 -1.92991589473267
Vibrio parahaemolyticus RIMD 2210633  VPA_1087  BAC62430.1  Q87H78  rbsD  139 aa ribose ABC transporter protein n.s. ●●○○○ -1.93 -1.92657924441504
Vibrio parahaemolyticus RIMD 2210633  VP_0839  BAC59102.1  Q87RF8  548 aa phosphoglucomutase n.s. ●●○○○ -1.93 -1.92600723213294
Haemophilus influenzae Rd KW20  HI_0330  NP_438494.1  P44415  oapA  431 aa opacity associated protein n.s. ●●○○○ -1.92 -1.92098973413151
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1446  CBW17541.1  A0A0H3NBJ8  ydeE  395 aa hypothetical membrane protein n.s. ●●○○○ -1.92 -1.92092839112807
Escherichia coli CFT073  c1729  AAN80194.1  A0A0H2V787  trpD  531 aa Anthranilate synthase component II n.s. ●●○○○ -1.92 -1.92046219264402
Escherichia coli CFT073  c1331  AAN79804.1  P0AC60  grxB  215 aa Glutaredoxin 2 n.s. ●●○○○ -1.92 -1.92046219264402
Escherichia coli CFT073  c2045  AAN80505.1  P66681  rnt  215 aa Ribonuclease T n.s. ●●○○○ -1.92 -1.92046219264402
Escherichia coli CFT073  c2561  AAN81016.1  A0A0H2V8Q0  381 aa Hypothetical protein n.s. ●●○○○ -1.92 -1.92046219264402
Escherichia coli CFT073  c1791  AAN80257.1  A0A0H2V7C7  ompG  318 aa Outer membrane protein G precursor n.s. ●●○○○ -1.92 -1.92046219264401
Streptococcus pyogenes M1 5448  SP5448_01175  WP_011285380.1  448 aa sensor histidine kinase n.s. ●●○○○ -1.92 -1.91996554495443
Haemophilus influenzae Rd KW20  HI_1388  NP_439540.1  P71381  trpG  193 aa anthranilate synthase component II n.s. ●●○○○ -1.92 -1.91783773531513
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2822  CBW18920.1  A0A0H3NQW9  hydA  746 aa hydrogenase maturation protein n.s. ●●○○○ -1.92 -1.91753843412791
Serratia marcescens Strain UMH9  BVG96_22235  ASM00161.1  334 aa protease modulator HflC n.s. ●●○○○ -1.92 -1.9161232088139
Streptococcus pyogenes M1 5448  SP5448_01580  WP_002982901.1  560 aa ribonuclease J n.s. ●●○○○ -1.92 -1.91612019896217
Escherichia coli CFT073  c1084  AAN79552.1  Q8FJ88  rlmL  702 aa Hypothetical protein ycbY n.s. ●●○○○ -1.92 -1.9155653140674
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4051  CBW20140.1  A0A0H3NNV9  239 aa inner membrane protein n.s. ●●○○○ -1.91 -1.91469155931987
Serratia marcescens Strain UMH9  BVG96_07560  ASL97478.1  206 aa TetR family transcriptional regulator n.s. ●●○○○ -1.91 -1.91057990256088
Streptococcus pyogenes M1 5448  SP5448_03880  WP_010922433.1  75 aa hypothetical protein n.s. ●●○○○ -1.91 -1.91035217997378
Escherichia coli CFT073  c2026  AAN80486.1  Q8FH91  dtpA  500 aa Hypothetical transporter ydgR n.s. ●●○○○ -1.91 -1.9098273091173
Escherichia coli CFT073  c1838  AAN80301.1  A0A0H2V753  220 aa Hypothetical protein n.s. ●●○○○ -1.91 -1.90967501904151
Escherichia coli CFT073  c1710  AAN80177.1  A0A0H2V700  oppD  337 aa Oligopeptide transport ATP-binding protein oppD n.s. ●●○○○ -1.91 -1.90935696843527
Escherichia coli CFT073  c1242  AAN79699.1  A0A0H2V6Z7  focD  892 aa F1C fimbrial usher n.s. ●●○○○ -1.91 -1.90935696843527
Haemophilus influenzae Rd KW20  HI_1077  NP_439233.1  P44341  pyrG  545 aa CTP synthetase n.s. ●●○○○ -1.9 -1.90447549563688
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0771  CBW16869.1  A0A0H3N9A5  bioB  346 aa biotin synthetase n.s. ●●○○○ -1.9 -1.90400737651556
Escherichia coli CFT073  c1976  AAN80436.1  A0A0H2V8R2  ynfD  115 aa Hypothetical protein ynfD precursor n.s. ●●○○○ -1.9 -1.90353395934173
Escherichia coli CFT073  c1921  AAN80379.1  Q8FHG6  gadC  511 aa Amino acid antiporter n.s. ●●○○○ -1.9 -1.90327649325443
Escherichia coli CFT073  c2166  AAN80625.1  A0A0H2V7V3  topB  667 aa DNA topoisomerase III n.s. ●●○○○ -1.9 -1.90273732861418
Vibrio parahaemolyticus RIMD 2210633  VPA_1640  BAC62983.1  Q87FN8  53 aa hypothetical protein n.s. ●●○○○ -1.9 -1.9023728874258
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2885  CBW18983.1  A0A0H3NFA6  175 aa salmonella pathogenicity island 1 protein n.s. ●●○○○ -1.9 -1.90197917356369
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1370  CBW17466.1  A0A0H3NKZ9  ydhL  79 aa conserved hypothetical protein n.s. ●●○○○ -1.9 -1.90153345296713
Haemophilus influenzae Rd KW20  HI_1084  NP_439241.1  P45028  mlaC  214 aa ABC transporter n.s. ●●○○○ -1.9 -1.90003342763982
Serratia marcescens Strain UMH9  BVG96_11815  ASL98269.1  306 aa lipid A biosynthesis lauroyl acyltransferase n.s. ●●○○○ -1.9 -1.90002974239468
Escherichia coli CFT073  c2586  AAN81042.1  A0A0H2VB13  732 aa Tyrosine-protein kinase wzc n.s. ●●○○○ -1.9 -1.89972894099193
Escherichia coli CFT073  c2799  AAN81253.1  Q8FFL9  arnT  550 aa Hypothetical protein yfbI n.s. ●●○○○ -1.9 -1.89883610819746
Escherichia coli CFT073  c1892  AAN80352.1  A0A0H2V7J8  155 aa Hypothetical protein n.s. ●●○○○ -1.9 -1.89521155476792
Escherichia coli CFT073  c2326  AAN80785.1  P0A8G1  uvrC  610 aa Excinuclease ABC subunit C n.s. ●●○○○ -1.89 -1.89433579092093
Serratia marcescens Strain UMH9  BVG96_14850  ASL98827.1  141 aa nucleoside-diphosphate kinase n.s. ●●○○○ -1.89 -1.89325820792552
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3226  CBW19322.1  A0A0H3NG96  gatY  284 aa tagatose-bisphosphate aldolase n.s. ●●○○○ -1.89 -1.89257917448017
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1887  CBW17982.1  A0A0H3NCT3  fliB  401 aa lysine-N-methylase (ec 2.1.1.-) (lysine N-methyltransferase) n.s. ●●○○○ -1.89 -1.89228745968315
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1177  CBW17273.1  A0A0H3NAR7  374 aa predicted bacteriophage protein n.s. ●●○○○ -1.89 -1.89206407792382
Escherichia coli CFT073  c2714  AAN81168.1  A0A0H2V8V6  yejA  606 aa Hypothetical protein yejA precursor n.s. ●●○○○ -1.89 -1.89174632243212
Streptococcus pyogenes M1 5448  SP5448_06725  WP_002990434.1  452 aa streptolysin associated protein SagD n.s. ●●○○○ -1.89 -1.88920277701636
Vibrio parahaemolyticus RIMD 2210633  VP_2716  BAC60978.1  Q87L97  125 aa hypothetical protein n.s. ●●○○○ -1.89 -1.88833850184373
Serratia marcescens Strain UMH9  BVG96_10320  ASL97991.1  270 aa septum site-determining protein MinD n.s. ●●○○○ -1.89 -1.8876950890586
Haemophilus influenzae Rd KW20  HI_0540  NP_438698.1  P44392  ureB  101 aa urease subunit beta n.s. ●●○○○ -1.89 -1.88585849573795
Escherichia coli CFT073  c2204  AAN80663.1  A0A0H2V838  yeaR  119 aa Hypothetical protein yeaR n.s. ●●○○○ -1.88 -1.88371490202884
Streptococcus pyogenes M1 5448  SP5448_06840  WP_011285462.1  515 aa zinc ABC transporter substrate-binding protein AdcA n.s. ●●○○○ -1.88 -1.88343475802797
Escherichia coli CFT073  c2602  AAN81058.1  Q8FG03  mdtC  1025 aa Hypothetical protein yegO n.s. ●●○○○ -1.88 -1.8824796417746
Vibrio parahaemolyticus RIMD 2210633  VP_0611  BAC58874.1  Q87S13  bamB  386 aa conserved hypothetical protein n.s. ●●○○○ -1.88 -1.8824444094528
Escherichia coli CFT073  c2184  AAN80643.1  P0A9B3  gapA  334 aa Glyceraldehyde 3-phosphate dehydrogenase A n.s. ●●○○○ -1.88 -1.88183033604426
Escherichia coli CFT073  c2237  AAN80696.1  A0A0H2VA82  yebQ  494 aa Hypothetical transport protein yebQ n.s. ●●○○○ -1.88 -1.88076390697457
Streptococcus pyogenes M1 5448  SP5448_03395  WP_010922487.1  469 aa deoxyribodipyrimidine photo-lyase n.s. ●●○○○ -1.88 -1.88055074853377
Vibrio parahaemolyticus RIMD 2210633  VP_2654  BAC60917.1  Q87LF8  pyrB  309 aa aspartate carbamoyltransferase, catalytic subunit n.s. ●●○○○ -1.88 -1.88050400537325
Streptococcus pyogenes M1 5448  SP5448_05475  WP_002989868.1  119 aa dihydroneopterin aldolase n.s. ●●○○○ -1.88 -1.87958941203571
Escherichia coli CFT073  c2296  AAN80755.1  P0A9I0  cheZ  224 aa Chemotaxis protein cheZ n.s. ●●○○○ -1.88 -1.87953129356922
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2861  CBW18959.1  E1WAC6  sipA  685 aa pathogenicity island 1 Type III secretion system effector protein-involved in actin bundling and polymerisation leading to epithelial cell invasion and formation of the SCV n.s. ●●○○○ -1.88 -1.87928563561303
Escherichia coli CFT073  c1833  AAN80296.1  A0A0H2V748  74 aa Hypothetical protein n.s. ●●○○○ -1.88 -1.87924691208221
Escherichia coli CFT073  c1940  AAN80398.1  Q8FHF4  hipA  472 aa Protein hipA n.s. ●●○○○ -1.88 -1.87821968089231
Haemophilus influenzae Rd KW20  HI_1432  NP_439581.1  P43759  trpA  268 aa tryptophan synthase subunit alpha n.s. ●●○○○ -1.88 -1.87791130095433
Streptococcus pyogenes M1 5448  SP5448_05540  WP_010922275.1  249 aa lantibiotic immunity ABC transporter MutE/EpiE family permease subunit n.s. ●●○○○ -1.88 -1.87766673903958
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3439  CBW19534.1  A0A0H3NGU9  ppiA  190 aa peptidyl-prolyl cis-trans isomerase n.s. ●●○○○ -1.88 -1.87695297381488
Streptococcus pyogenes M1 5448  SP5448_05050  WP_010922334.1  160 aa hypothetical protein n.s. ●●○○○ -1.88 -1.87670540254152
Vibrio parahaemolyticus RIMD 2210633  VP_3045  BAC61308.1  Q87KD2  458 aa potassium uptake protein TrkA n.s. ●●○○○ -1.88 -1.87651008403792
Escherichia coli CFT073  c0768  AAN79241.1  A0A0H2V5X6  ybfM  468 aa Hypothetical protein ybfM n.s. ●●○○○ -1.87 -1.8735419900551
Escherichia coli CFT073  c2579  AAN81034.1  P0AC89  gmd  373 aa GDP-mannose 4,6-dehydratase n.s. ●●○○○ -1.87 -1.87288341258319
Escherichia coli CFT073  c1548  AAN80017.1  A0A0H2V8W7  98 aa Putative Regulatory protein CII of bacteriophage n.s. ●●○○○ -1.87 -1.87288341258318
Vibrio parahaemolyticus RIMD 2210633  VP_2539  BAC60802.1  Q87LS2  gshA  522 aa glutamate-cysteine ligase n.s. ●●○○○ -1.87 -1.87178897993943
Haemophilus influenzae Rd KW20  HI_1389  NP_439542.1  P43858  trpD  333 aa anthranilate phosphoribosyltransferase n.s. ●●○○○ -1.87 -1.87151580926986
Escherichia coli CFT073  c1979  AAN80439.1  P0AAJ2  ynfG  205 aa Probable anaerobic dimethyl sulfoxide reductase chain ynfG n.s. ●●○○○ -1.87 -1.86850798318373
Escherichia coli CFT073  c0777  AAN79250.1  A0A0H2V5Y3  speF  735 aa Ornithine decarboxylase, inducible n.s. ●●○○○ -1.87 -1.86850798318373
Escherichia coli CFT073  c1980  AAN80440.1  A0A0H2V9R5  48 aa Hypothetical protein n.s. ●●○○○ -1.87 -1.86850798318373
Vibrio parahaemolyticus RIMD 2210633  VP_2187  BAC60450.1  Q87MP4  202 aa DedD protein n.s. ●●○○○ -1.87 -1.86817904348051
Haemophilus influenzae Rd KW20  HI_0229  NP_438401.1  P44584  pnp  709 aa polynucleotide phosphorylase/polyadenylase n.s. ●●○○○ -1.87 -1.86790345827428
Escherichia coli CFT073  c2002  AAN80462.1  Q8FHA8  tus  313 aa DNA replication terminus site-binding protein n.s. ●●○○○ -1.87 -1.86697073492441
Escherichia coli CFT073  c1708  AAN80175.1  P0AFH3  oppB  306 aa Oligopeptide transport system permease protein oppB n.s. ●●○○○ -1.87 -1.86686501068033
Vibrio parahaemolyticus RIMD 2210633  VPA_0262  BAC61605.1  Q79YV2  93 aa LfgM n.s. ●●○○○ -1.87 -1.86504890523982
Escherichia coli CFT073  c1962  AAN80419.1  A0A0H2V9P9  ydeF  395 aa Hypothetical protein ydeE n.s. ●●○○○ -1.86 -1.86438217906402
Streptococcus pyogenes M1 5448  SP5448_03520  WP_011284879.1  79 aa hypothetical protein n.s. ●●○○○ -1.86 -1.86420802806667
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0375  CBW16475.1  A0A0H3N9T7  ddlA  364 aa D-alanine:D-alanine ligase A n.s. ●●○○○ -1.86 -1.86306165344653
Escherichia coli CFT073  c2555  AAN81010.1  Q8FG45  ugd  388 aa UDP-glucose 6-dehydrogenase n.s. ●●○○○ -1.86 -1.86019439227938
Escherichia coli CFT073  c1608  AAN80076.1  A0A0H2V7Z2  57 aa Hypothetical protein n.s. ●●○○○ -1.86 -1.86019439227938
Escherichia coli CFT073  c1961  AAN80418.1  A0A0H2V7N9  ydeD  306 aa Probable amino acid metabolite efflux pump n.s. ●●○○○ -1.86 -1.85960418371532
Streptococcus pyogenes M1 5448  SP5448_05715  WP_002989951.1  113 aa CRISPR-associated endonuclease Cas2 n.s. ●●○○○ -1.86 -1.85940134557635
Porphyromonas gingivalis ATCC 33277  PGN_1813  WP_004583549.1  B2RLT7  hflX  406 aa GTPase HflX n.s. ●●○○○ -1.86 -1.85935031769752
Escherichia coli CFT073  c2260  AAN80719.1  P0ACZ0  yebG  96 aa Hypothetical protein yebG n.s. ●●○○○ -1.86 -1.85910343952882
Escherichia coli CFT073  c1767  AAN80233.1  P0AAH9  sapF  268 aa Peptide transport system ATP-binding protein sapF n.s. ●●○○○ -1.86 -1.85888049190581
Escherichia coli CFT073  c0142  AAN78638.1  A0A0H2V5Y0  aceE  887 aa Pyruvate dehydrogenase E1 component n.s. ●●○○○ -1.86 -1.85854301582382
Streptococcus pyogenes M1 5448  SP5448_05850  WP_010922233.1  332 aa peptide ABC transporter substrate-binding protein n.s. ●●○○○ -1.85 -1.85459466308602
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