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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Vibrio parahaemolyticus RIMD 2210633  VP_1619  BAC59882.1  Q87P99  306 aa uroporphyrin-III C-methyltransferase n.s. ●●○○○ -1.85 -1.85410670584739
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0819  CBW16916.1  A0A0H3NEN9  pflF  810 aa hypothetical formate acetyltransferase 3 n.s. ●●○○○ -1.85 -1.85233893540847
Escherichia coli CFT073  c2650  AAN81106.1  A0A0H2VA98  yehM  784 aa Hypothetical protein yehM n.s. ●●○○○ -1.85 -1.8519748733336
Escherichia coli CFT073  c2064  AAN80524.1  A0A0H2V9W5  ydhU  261 aa PhsC protein homolog n.s. ●●○○○ -1.85 -1.85033246273437
Escherichia coli CFT073  c2957  AAN81407.1  P0AEB1  cysW  291 aa Putative conserved protein n.s. ●●○○○ -1.85 -1.84836083426105
Serratia marcescens Strain UMH9  BVG96_09515  ASL97846.1  549 aa peptide ABC transporter substrate-binding protein SapA n.s. ●●○○○ -1.85 -1.84802916707932
Streptococcus pyogenes M1 5448  SP5448_01505  WP_002988149.1  534 aa CTP synthase n.s. ●●○○○ -1.85 -1.84786530759957
Serratia marcescens Strain UMH9  BVG96_00065  ASL96101.1  388 aa Na+/H+ antiporter NhaA n.s. ●●○○○ -1.85 -1.84784264723466
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0747  CBW16845.1  A0A0H3NEF5  359 aa ABC transporter permease (FecCD_family) n.s. ●●○○○ -1.85 -1.84727708688981
Escherichia coli CFT073  c1912  AAN80371.1  Q8FHH1  maeA  574 aa NAD-dependent malic enzyme n.s. ●●○○○ -1.85 -1.84636019074642
Escherichia coli CFT073  c2757  AAN81211.1  A0A0H2V8Y4  364 aa Hypothetical protein n.s. ●●○○○ -1.85 -1.84574766639549
Escherichia coli CFT073  c2758  AAN81212.1  Q8CVW1  ompC  375 aa Outer membrane protein C precursor n.s. ●●○○○ -1.85 -1.84574766639549
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2862  CBW18960.1  A0A0H3NGZ6  sipD  343 aa pathogenicity island 1 Type III secretion system apparatus-part of the Translocon n.s. ●●○○○ -1.85 -1.84510592071327
Streptococcus pyogenes M1 5448  SP5448_06475  WP_002990272.1  162 aa pore forming protein ebsA n.s. ●●○○○ -1.84 -1.84305862510925
Escherichia coli CFT073  c1899  AAN80359.1  A0A0H2V7D5  narY  514 aa Respiratory nitrate reductase 2 beta chain n.s. ●●○○○ -1.84 -1.84155462558804
Escherichia coli CFT073  c3376  AAN81821.1  Q8FEE5  rlmM  366 aa Hypothetical protein ygdE n.s. ●●○○○ -1.84 -1.84080959258789
Streptococcus pyogenes M1 5448  SP5448_02150  WP_011285677.1  486 aa NCS2 family permease n.s. ●●○○○ -1.84 -1.83921327911699
Serratia marcescens Strain UMH9  BVG96_16895  ASL99195.1  254 aa transcriptional regulator PdhR n.s. ●●○○○ -1.84 -1.83910533630768
Vibrio parahaemolyticus RIMD 2210633  VP_0419  BAC58682.1  Q87SK4  228 aa conserved hypothetical protein n.s. ●●○○○ -1.84 -1.83691697645596
Haemophilus influenzae Rd KW20  HI_0122  NP_438294.1  P44527  metC  396 aa cystathionine beta-lyase n.s. ●●○○○ -1.84 -1.83547024200475
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3936  CBW20027.1  A0A0H3NJR8  fadB  729 aa large (alpha) subunit of the fatty acid-oxidizing multienzyme complex n.s. ●●○○○ -1.83 -1.83220732204002
Haemophilus influenzae Rd KW20  HI_0055  NP_438228.1  P44488  uxuA  394 aa mannonate dehydratase n.s. ●●○○○ -1.83 -1.83117510628026
Streptococcus pyogenes M1 5448  SP5448_02700  WP_010922557.1  416 aa glutamate-5-semialdehyde dehydrogenase n.s. ●●○○○ -1.83 -1.83056125063441
Streptococcus pyogenes M1 5448  SP5448_02700  WP_046735268.1  68 aa hypothetical protein n.s. ●●○○○ -1.83 -1.83056125063441
Escherichia coli CFT073  c0918  AAN79391.1  A0A0H2V5H2  yliE  782 aa Hypothetical protein yliE n.s. ●●○○○ -1.83 -1.83033847077697
Escherichia coli CFT073  c2373  AAN80832.1  P59286  yedP  271 aa Hypothetical protein yedP n.s. ●●○○○ -1.83 -1.82973348922367
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3015  CBW19114.1  A0A0H3NHJ9  idi  181 aa Isopentenyl-diphosphate delta-isomerase n.s. ●●○○○ -1.83 -1.82959286349589
Escherichia coli CFT073  c3029  AAN81479.1  A0A0H2VBV9  2683 aa RatA homolog n.s. ●●○○○ -1.83 -1.82955781907868
Escherichia coli CFT073  c1254  AAN79728.1  A0A0H2V630  iroB  387 aa Putative glucosyltransferase n.s. ●●○○○ -1.83 -1.82944686247728
Escherichia coli CFT073  c1987  AAN80447.1  A0A0H2V9S0  ynfM  417 aa Hypothetical transport protein ynfM n.s. ●●○○○ -1.83 -1.82927195372142
Streptococcus pyogenes M1 5448  SP5448_06715  WP_010922110.1  227 aa hypothetical protein n.s. ●●○○○ -1.83 -1.82767724114021
Vibrio parahaemolyticus RIMD 2210633  VP_2737  BAC61000.1  Q87L75  rplI  150 aa ribosomal protein L9 n.s. ●●○○○ -1.83 -1.82751823304991
Vibrio parahaemolyticus RIMD 2210633  VP_2823  BAC61086.1  Q87L01  orn  181 aa oligoribonuclease n.s. ●●○○○ -1.83 -1.82751823304991
Escherichia coli CFT073  c0145  AAN78639.1  P0A9P1  lpdA  495 aa Dihydrolipoamide dehydrogenase n.s. ●●○○○ -1.83 -1.82744871152581
Escherichia coli CFT073  c2313  AAN80772.1  P0AAF4  araG  519 aa L-arabinose transport ATP-binding protein araG n.s. ●●○○○ -1.83 -1.82744871152581
Vibrio parahaemolyticus RIMD 2210633  VP_0470  BAC58733.1  Q87SF4  carA  379 aa carbamoyl-phosphate synthase, small subunit n.s. ●●○○○ -1.83 -1.82647178342076
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0016  CBW16117.1  A0A0H3N7A6  177 aa conserved hypothetical protein n.s. ●●○○○ -1.83 -1.82621693746966
Escherichia coli CFT073  c1611  AAN80079.1  A0A0H2V724  84 aa Hypothetical protein n.s. ●●○○○ -1.83 -1.82562693909432
Vibrio parahaemolyticus RIMD 2210633  VP_0844  BAC59107.1  Q87RF3  114 aa succinate dehydrogenase, hydrophobic membrane anchor protein n.s. ●●○○○ -1.83 -1.82534316236906
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3952  CBW20042.1  A0A0H3NJT7  glnG  469 aa Two-component system, response regulator n.s. ●●○○○ -1.83 -1.82521341768132
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4058  CBW20147.1  A0A0H3NV32  gldA  367 aa glycerol dehydrogenase n.s. ●●○○○ -1.83 -1.82521037835546
Escherichia coli CFT073  c2410  AAN80869.1  A0A0H2V8A3  159 aa Hypothetical protein n.s. ●●○○○ -1.82 -1.8242813549052
Streptococcus pyogenes M1 5448  SP5448_08565  WP_010922690.1  440 aa streptokinase n.s. ●●○○○ -1.82 -1.82383189514795
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0521  CBW16620.1  A0A0H3NIL1  allD  349 aa ureidoglycolate dehydrogenase n.s. ●●○○○ -1.82 -1.82339004776824
Escherichia coli CFT073  c2146  AAN80605.1  Q8FH01  astD  492 aa Succinylglutamic semialdehyde dehydrogenase n.s. ●●○○○ -1.82 -1.82261536988402
Serratia marcescens Strain UMH9  BVG96_13370  ASL98555.1  718 aa phosphate acetyltransferase n.s. ●●○○○ -1.82 -1.82133012988799
Escherichia coli CFT073  c1814  AAN80278.1  A0A0H2V9G1  ydaL  187 aa Hypothetical protein ydaL n.s. ●●○○○ -1.82 -1.82110955287032
Escherichia coli CFT073  c1748  AAN80214.1  A0A0H2V869  yciS  102 aa Hypothetical protein yciS n.s. ●●○○○ -1.82 -1.81974186510522
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4017  CBW20106.1  A0A0H3NUZ9  240 aa hypothetical GntR-family regulatory protein n.s. ●●○○○ -1.82 -1.81973669111818
Vibrio parahaemolyticus RIMD 2210633  VPA_1027  BAC62370.1  Q87HD8  159 aa hypothetical protein n.s. ●●○○○ -1.82 -1.81955073385969
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3725  CBW19817.1  A0A0H3NTV2  marT  262 aa hypothetical transcriptional regulator (MarT) n.s. ●●○○○ -1.82 -1.81909381676088
Escherichia coli CFT073  c2394  AAN80853.1  A0A0H2V9L7  487 aa PilV-like protein n.s. ●●○○○ -1.82 -1.81835449974077
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3427  CBW19522.1  A0A0H3NGU8  73 aa conserved hypothetical protein n.s. ●●○○○ -1.82 -1.817851830361
Escherichia coli CFT073  c2883  AAN81333.1  A0A0H2V9D4  yfcU  884 aa Putative outer membrane protein n.s. ●●○○○ -1.82 -1.81772138345174
Vibrio parahaemolyticus RIMD 2210633  VP_0324  BAC58587.1  Q87SU8  argR  173 aa arginine repressor n.s. ●●○○○ -1.81 -1.81403927626527
Escherichia coli CFT073  c1245  AAN79702.1  A0A0H2V868  focH  336 aa F1C Putative fimbrial adhesin precursor n.s. ●●○○○ -1.81 -1.81391478361327
Haemophilus influenzae Rd KW20  HI_0950  NP_439111.1  P44369  rpmG  56 aa 50S ribosomal protein L33 n.s. ●●○○○ -1.81 -1.81238491808059
Haemophilus influenzae Rd KW20  HI_1083  NP_439240.1  Q57407  mlaB  105 aa NTP binding protein n.s. ●●○○○ -1.81 -1.81238491808059
Streptococcus pyogenes M1 5448  SP5448_03900  WP_010922429.1  342 aa tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA n.s. ●●○○○ -1.81 -1.81037318417504
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3424  CBW19519.1  A0A0H3NGT6  kefB  601 aa glutathione-regulated potassium-efflux system protein (K(+)/H(+)antiporter) n.s. ●●○○○ -1.81 -1.81014733369779
Escherichia coli CFT073  c2177  AAN80636.1  A0A0H2V7W1  ydjI  278 aa Hypothetical protein ydjI n.s. ●●○○○ -1.81 -1.80784558370529
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4486  CBW20575.1  A0A0H3NQ28  rimI  148 aa ribosomal-protein-alanine acetyltransferase n.s. ●●○○○ -1.81 -1.80747530791424
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2702  CBW18804.1  A0A0H3NEW3  285 aa DNA adenine methylase n.s. ●●○○○ -1.81 -1.80618070013832
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3848  CBW19939.1  A0A0H3NHS4  rbsD  139 aa high affinity ribose transport protein RbsD n.s. ●●○○○ -1.81 -1.80558086421746
Streptococcus pyogenes M1 5448  SP5448_04565  WP_009880255.1  168 aa phage major tail protein, TP901-1 family n.s. ●●○○○ -1.8 -1.80364382868859
Escherichia coli CFT073  c1214  AAN79674.1  A0A0H2V850  79 aa Cea protein n.s. ●●○○○ -1.8 -1.80189932177157
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3659  CBW19752.1  A0A0H3NHC6  lctD  396 aa hypothetical L-lactate dehydrogenase n.s. ●●○○○ -1.8 -1.80131931418104
Escherichia coli CFT073  c1374  AAN79844.1  A0A0H2V6A0  fhuE  729 aa FhuE receptor precursor n.s. ●●○○○ -1.8 -1.79928342809194
Escherichia coli CFT073  c2920  AAN81370.1  Q8FFE0  ypdB  251 aa Hypothetical protein ypdB n.s. ●●○○○ -1.8 -1.79856184220555
Escherichia coli CFT073  c1726  AAN80193.1  Q8FHV9  trpB  397 aa Tryptophan synthase beta chain n.s. ●●○○○ -1.8 -1.79706184169638
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3601  CBW19695.1  A0A0H3NIX4  lpfE  175 aa fimbrial protein (LpfE) n.s. ●●○○○ -1.79 -1.79326555326377
Escherichia coli CFT073  c2131  AAN80590.1  A0A0H2V921  katE  753 aa Catalase HPII n.s. ●●○○○ -1.79 -1.79310970788708
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2877  CBW18975.1  A0A0H3NR16  invG  562 aa type III secretion system secretory apparatus n.s. ●●○○○ -1.79 -1.79141514709801
Escherichia coli CFT073  c3195  AAN81647.1  A0A0H2VC87  ymfL  202 aa Hypothetical protein ymfL n.s. ●●○○○ -1.79 -1.791289402852
Escherichia coli CFT073  c1927  AAN80385.1  A0A0H2V9M9  ydeN  571 aa Putative sulfatase ydeN precursor n.s. ●●○○○ -1.79 -1.791289402852
Vibrio parahaemolyticus RIMD 2210633  VP_1544  BAC59807.1  Q87PF8  477 aa cytochrome c oxidase, subunit CcoN n.s. ●●○○○ -1.79 -1.79103559496724
Vibrio parahaemolyticus RIMD 2210633  VPA_1722  BAC63065.1  Q87FF7  79 aa hypothetical protein n.s. ●●○○○ -1.79 -1.79066665932367
Haemophilus influenzae Rd KW20  HI_0016  NP_438189.1  P43729  lepA  598 aa GTP-binding protein LepA n.s. ●●○○○ -1.79 -1.79054751895703
Escherichia coli CFT073  c0348  AAN78831.1  A0A0H2V4I4  80 aa Hypothetical protein n.s. ●●○○○ -1.79 -1.78984398637875
Escherichia coli CFT073  c1054  AAN79524.1  Q8FJB1  msbA  582 aa Probable transport ATP-binding protein msbA n.s. ●●○○○ -1.79 -1.78941629161431
Vibrio parahaemolyticus RIMD 2210633  VP_0716  BAC58979.1  Q87RR1  lipA  321 aa lipoic acid synthetase n.s. ●●○○○ -1.79 -1.7888729687335
Vibrio parahaemolyticus RIMD 2210633  VP_3068  BAC61331.1  Q87KA9  atpC  140 aa ATP synthase F1, epsilon subunit n.s. ●●○○○ -1.79 -1.7888729687335
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4684  AIK83218.1  686 aa polyphosphate kinase 1 n.s. ●●○○○ -1.79 -1.78792454529643
Escherichia coli CFT073  c1851  AAN80314.1  A0A0H2V7G8  rimL  184 aa Ribosomal-protein-serine acetyltransferase n.s. ●●○○○ -1.79 -1.78778838189018
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2448  CBW18550.1  A0A0H3NK73  ypfI  672 aa conserved hypothetical protein n.s. ●●○○○ -1.79 -1.78762116077025
Escherichia coli CFT073  c1508  AAN79977.1  Q8FIB8  phoQ  486 aa Sensor protein phoQ n.s. ●●○○○ -1.79 -1.78731768200742
Escherichia coli CFT073  c1360  AAN79831.1  P0A6R1  fabH  317 aa 3-oxoacyl-[acyl-carrier-protein] synthase III n.s. ●●○○○ -1.79 -1.78731768200742
Vibrio parahaemolyticus RIMD 2210633  VP_0214  BAC58477.1  Q87T56  hldD  313 aa ADP glyceromanno-heptose 6-epimerase GmhD n.s. ●●○○○ -1.79 -1.78617444003508
Escherichia coli CFT073  c3489  AAN81937.1  A0A0H2VAA4  ubiH  392 aa 2-octaprenyl-6-methoxyphenol hydroxylase n.s. ●●○○○ -1.78 -1.78463281901458
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0034  CBW16135.1  A0A0H3NGZ9  523 aa hypothetical secreted 5'-nucleotidase n.s. ●●○○○ -1.78 -1.78379804942251
Streptococcus pyogenes M1 5448  SP5448_04715  WP_010922372.1  278 aa amino acid ABC transporter substrate-binding protein n.s. ●●○○○ -1.78 -1.78249442573117
Vibrio parahaemolyticus RIMD 2210633  VPA_0770  BAC62113.1  Q87I36  156 aa hypothetical protein n.s. ●●○○○ -1.78 -1.78205750926561
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1217  CBW17312.1  A0A0H3NAJ8  yeaK  172 aa conserved hypothetical protein n.s. ●●○○○ -1.78 -1.78187258053542
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1920  CBW18015.1  A0A0H3NCL7  dcm  476 aa DNA-cytosine methyltransferase n.s. ●●○○○ -1.78 -1.78162857531936
Escherichia coli CFT073  c1898  AAN80358.1  A0A0H2V9K8  narW  231 aa Respiratory nitrate reductase 2 delta chain n.s. ●●○○○ -1.78 -1.78036667216931
Vibrio parahaemolyticus RIMD 2210633  VP_0918  BAC59181.1  Q87R79  clpX  426 aa ATP-dependent Clp protease, ATP-binding subunit ClpX n.s. ●●○○○ -1.78 -1.77875543628472
Escherichia coli CFT073  c2355  AAN80814.1  P0ABZ2  fliG  331 aa Flagellar motor switch protein fliG n.s. ●●○○○ -1.78 -1.7785932538476
Serratia marcescens Strain UMH9  BVG96_07830  ASL97529.1  302 aa LysR family transcriptional regulator n.s. ●●○○○ -1.78 -1.7776161016585
Streptococcus pyogenes M1 5448  SP5448_01545  WP_002992286.1  554 aa DAK2 domain-containing protein n.s. ●●○○○ -1.78 -1.77672640674278
Escherichia coli CFT073  c2429  AAN80888.1  A0A0H2V8E0  1569 aa Hypothetical protein n.s. ●●○○○ -1.78 -1.77667393668717
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