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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Vibrio parahaemolyticus RIMD 2210633  VP_0684  BAC58947.1  Q87RU2  thiL  321 aa thiamin-monophosphate kinase n.s. ●●○○○ -1.78 -1.77613464124055
Streptococcus pyogenes M1 5448  SP5448_07235  WP_010922008.1  113 aa Fic family protein n.s. ●●○○○ -1.78 -1.77576507024471
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3845  CBW19936.1  A0A0H3NHR8  yieM  466 aa conserved hypothetical protein n.s. ●●○○○ -1.77 -1.77429403416775
Escherichia coli CFT073  c1133  AAN79601.1  Q8CW73  torA  848 aa Trimethylamine-N-oxide reductase 1 precursor n.s. ●●○○○ -1.77 -1.77395873065682
Haemophilus influenzae Rd KW20  HI_0945  NP_439105.1  P44947  degS  340 aa protease n.s. ●●○○○ -1.77 -1.77390730978805
Streptococcus pyogenes M1 5448  SP5448_02645  WP_002983556.1  508 aa glycerol kinase GlpK n.s. ●●○○○ -1.77 -1.77384239724858
Escherichia coli CFT073  c1400  AAN79869.1  A0A0H2V6B1  372 aa Prophage lambda integrase n.s. ●●○○○ -1.77 -1.76958342769118
Vibrio parahaemolyticus RIMD 2210633  VPA_0218  BAC61561.1  Q87JN0  179 aa hypothetical protein n.s. ●●○○○ -1.77 -1.76921087040553
Vibrio parahaemolyticus RIMD 2210633  VP_1429  BAC59692.1  Q87PS2  33 aa hypothetical protein n.s. ●●○○○ -1.77 -1.7688864494839
Vibrio parahaemolyticus RIMD 2210633  VPA_0308  BAC61651.1  Q87JE5  241 aa conserved hypothetical protein n.s. ●●○○○ -1.77 -1.76866643553726
Escherichia coli CFT073  c1990  AAN80450.1  A0A0H2V8S4  273 aa Putative protease ydgD precursor n.s. ●●○○○ -1.77 -1.76832477626412
Haemophilus influenzae Rd KW20  HI_1085  NP_439242.1  P45029  mlaD  167 aa ABC transporter substrate-binding protein n.s. ●●○○○ -1.77 -1.76830941132866
Escherichia coli CFT073  c1375  AAN79845.1  A0A0H2V6E5  56 aa Hypothetical protein n.s. ●●○○○ -1.77 -1.76825241866934
Streptococcus pyogenes M1 5448  SP5448_03780  WP_002983928.1  231 aa phosphoglycerate mutase n.s. ●●○○○ -1.77 -1.76807437826019
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3226  AIK81786.1  466 aa soluble pyridine nucleotide transhydrogenase n.s. ●●○○○ -1.77 -1.76659442721355
Streptococcus pyogenes M1 5448  SP5448_03365  WP_010922490.1  100 aa DUF1827 family protein n.s. ●●○○○ -1.77 -1.76615170526406
Escherichia coli CFT073  c1187  AAN79649.1  A0A0H2V833  243 aa 3-oxoacyl-[acyl-carrier protein] reductase n.s. ●●○○○ -1.77 -1.76582537480729
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2736  CBW18836.1  A0A0H3NQH4  326 aa glucitol/sorbitol-specific phosphotransferase enzyme IIB component n.s. ●●○○○ -1.76 -1.76479710744981
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1088  CBW17184.1  A0A0H3NK42  mdoH  847 aa Glucans biosynthesis glucosyltransferase H n.s. ●●○○○ -1.76 -1.76471295406948
Escherichia coli CFT073  c2832  AAN81286.1  Q8FFJ5  yfbR  199 aa Hypothetical protein yfbR n.s. ●●○○○ -1.76 -1.76342334597651
Escherichia coli CFT073  c2655  AAN81111.1  P0AFT6  btsR  244 aa Hypothetical protein yehT n.s. ●●○○○ -1.76 -1.76342334597651
Streptococcus pyogenes M1 5448  SP5448_04015  WP_010922417.1  424 aa deacetylase n.s. ●●○○○ -1.76 -1.7623063592718
Vibrio parahaemolyticus RIMD 2210633  VPA_1619  BAC62962.1  Q87FQ9  726 aa 4-alpha-glucanotransferase n.s. ●●○○○ -1.76 -1.7610130130578
Streptococcus pyogenes M1 5448  SP5448_04520  WP_011285568.1  89 aa hypothetical protein n.s. ●●○○○ -1.76 -1.76038368627567
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1677  CBW17772.1  A0A0H3NBY2  oppA  543 aa periplasmic oligopeptide-binding protein precursor (OppA) n.s. ●●○○○ -1.76 -1.75970544759072
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3715  CBW19809.1  A0A0H3NN11  yicI  772 aa hypothetical glycosyl hydrolase n.s. ●●○○○ -1.76 -1.75930969766668
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0058  CBW16159.1  A0A0H3NCK3  446 aa citrate-sodium symporter n.s. ●●○○○ -1.76 -1.75895689542151
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0498  CBW16598.1  A0A0H3NDT3  ybbO  256 aa hypothetical oxidoreductase n.s. ●●○○○ -1.76 -1.75644321240951
Serratia marcescens Strain UMH9  BVG96_01575  ASL96372.1  303 aa recombination-associated protein RdgC n.s. ●●○○○ -1.75 -1.75375533108967
Escherichia coli CFT073  c1351  AAN79822.1  A0A0H2V692  flgK  547 aa Flagellar hook-associated protein 1 n.s. ●●○○○ -1.75 -1.75209329205527
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1100  CBW17196.1  A0A0H3NA71  pyrC  348 aa Dihydroorotase n.s. ●●○○○ -1.75 -1.75191688711524
Escherichia coli CFT073  c2759  AAN81213.1  A0A0H2V962  yojN  890 aa Putative sensor-like histidine kinase yojN n.s. ●●○○○ -1.75 -1.74936039718094
Escherichia coli CFT073  c2649  AAN81105.1  A0A0H2V8V7  yehL  384 aa Hypothetical protein yehL n.s. ●●○○○ -1.75 -1.74901253162513
Serratia marcescens Strain UMH9  BVG96_04040  ASL96820.1  155 aa hypothetical protein n.s. ●●○○○ -1.75 -1.74813344986074
Streptococcus pyogenes M1 5448  SP5448_07470  WP_002990729.1  48 aa 50S ribosomal protein L33 n.s. ●●○○○ -1.75 -1.74692497530277
Streptococcus pyogenes M1 5448  SP5448_07470  WP_002985700.1  78 aa preprotein translocase subunit SecG n.s. ●●○○○ -1.75 -1.74692497530277
Streptococcus pyogenes M1 5448  SP5448_05550  WP_010922273.1  205 aa ATP-binding cassette domain-containing protein n.s. ●●○○○ -1.75 -1.74500230230664
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0348  CBW16448.1  A0A0H3NHY6  762 aa hypothetical cation transport atpase (ec 3.6.1.-) n.s. ●●○○○ -1.74 -1.74488711976219
Escherichia coli CFT073  c1823  AAN80287.1  A0A0H2V771  ydbK  1174 aa Probable pyruvate-flavodoxin oxidoreductase n.s. ●●○○○ -1.74 -1.74116840824338
Streptococcus pyogenes M1 5448  SP5448_04195  WP_010922394.1  103 aa PTS sugar transporter subunit IIB n.s. ●●○○○ -1.74 -1.74115695631438
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3919  CBW20010.1  A0A0H3NHZ3  metE  754 aa 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase n.s. ●●○○○ -1.74 -1.74041099962766
Vibrio parahaemolyticus RIMD 2210633  VP_0418  BAC58681.1  Q87SK5  419 aa pho4 family protein n.s. ●●○○○ -1.74 -1.73938296548704
Streptococcus pyogenes M1 5448  SP5448_06360  WP_002985094.1  296 aa RluA family pseudouridine synthase n.s. ●●○○○ -1.74 -1.73827294682018
Streptococcus pyogenes M1 5448  SP5448_05695  WP_010922253.1  610 aa elongation factor 4 n.s. ●●○○○ -1.74 -1.73731161032212
Vibrio parahaemolyticus RIMD 2210633  VPA_0806  BAC62149.1  Q87I00  241 aa transcriptional regulator, TetR family n.s. ●●○○○ -1.74 -1.7366252424693
Porphyromonas gingivalis ATCC 33277  PGN_1307  WP_012458169.1  B2RKD1  75 aa hypothetical protein n.s. ●●○○○ -1.74 -1.73553843854971
Escherichia coli CFT073  c2279  AAN80736.1  A0A0H2V803  ntpA  147 aa dATP pyrophosphohydrolase n.s. ●●○○○ -1.73 -1.73490244073789
Escherichia coli CFT073  c2460  AAN80919.1  A0A0H2V8G9  1010 aa Putative polyketide synthase n.s. ●●○○○ -1.73 -1.73490244073789
Haemophilus influenzae Rd KW20  HI_1200  NP_439356.1  P45105  cysB  323 aa transcriptional regulator CysB n.s. ●●○○○ -1.73 -1.73416791807934
Haemophilus influenzae Rd KW20  HI_0041  NP_438214.1  P44318  xthA  267 aa exonuclease III n.s. ●●○○○ -1.73 -1.73416791807934
Haemophilus influenzae Rd KW20  HI_0416  NP_438578.1  P44697  thiD  269 aa phosphomethylpyrimidine kinase n.s. ●●○○○ -1.73 -1.73416791807934
Streptococcus pyogenes M1 5448  SP5448_06955  WP_010922038.1  260 aa PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC n.s. ●●○○○ -1.73 -1.73346626432986
Vibrio parahaemolyticus RIMD 2210633  VPA_0745  BAC62088.1  Q87I61  30 aa hypothetical protein n.s. ●●○○○ -1.73 -1.73299347475292
Vibrio parahaemolyticus RIMD 2210633  VP_0308  BAC58571.1  Q87SW4  1255 aa conserved hypothetical protein n.s. ●●○○○ -1.73 -1.73294741015186
Vibrio parahaemolyticus RIMD 2210633  VP_1822  BAC60085.1  Q87NP6  30 aa hypothetical protein n.s. ●●○○○ -1.73 -1.73171034529348
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2854  CBW18952.1  A0A0H3NL53  prgH  392 aa type III secretion apparatus component n.s. ●●○○○ -1.73 -1.73117719105487
Streptococcus pyogenes M1 5448  SP5448_04635  WP_009880241.1  73 aa hypothetical protein n.s. ●●○○○ -1.73 -1.73058225483567
Escherichia coli CFT073  c1974  AAN80434.1  A0A0H2V7I4  speG  186 aa Spermidine N(1)-acetyltransferase n.s. ●●○○○ -1.73 -1.72968671767559
Escherichia coli CFT073  c1157  AAN79625.1  Q8CW71  efeB  423 aa Hypothetical protein ycdB precursor n.s. ●●○○○ -1.73 -1.72968671767559
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2474  CBW18576.1  A0A0H3NEC1  shdA  2039 aa host colonisation factor (ShdA) n.s. ●●○○○ -1.73 -1.7294828308862
Escherichia coli CFT073  c2803  AAN81257.1  A0A0H2V910  menE  451 aa O-succinylbenzoic acid--CoA ligase n.s. ●●○○○ -1.73 -1.72922445839354
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3604  CBW19697.1  A0A0H3NH92  lpfC  842 aa outer membrane usher protein (LpfC) n.s. ●●○○○ -1.73 -1.72873018188118
Vibrio parahaemolyticus RIMD 2210633  VP_1341  BAC59604.1  Q87Q09  30 aa hypothetical protein n.s. ●●○○○ -1.73 -1.72747980021703
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3644  CBW19737.1  A0A0H3NHB5  651 aa conserved hypothetical protein n.s. ●●○○○ -1.73 -1.72667196094653
Streptococcus pyogenes M1 5448  SP5448_03450  WP_010922483.1  286 aa lipase n.s. ●●○○○ -1.73 -1.72577557234534
Escherichia coli CFT073  c2708  AAN81162.1  P0A6N9  yeiP  275 aa Protein yeiP n.s. ●●○○○ -1.72 -1.72382443532507
Escherichia coli CFT073  c1866  AAN80329.1  A0A0H2V7I2  ydcU  313 aa Hypothetical ABC transporter permease protein ydcU n.s. ●●○○○ -1.72 -1.72382443532506
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2031  CBW18127.1  A0A0H3ND03  pduU  116 aa hypothetical propanediol utilization protein PduU n.s. ●●○○○ -1.72 -1.72356697762623
Vibrio parahaemolyticus RIMD 2210633  VP_0845  BAC59108.1  Q87RF2  588 aa succinate dehydrogenase, flavoprotein subunit n.s. ●●○○○ -1.72 -1.72304122261781
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4520  CBW20609.1  A0A0H3NJG1  sthB  845 aa Outer membrane fimbrial usher protein n.s. ●●○○○ -1.72 -1.72165000628009
Escherichia coli CFT073  c2485  AAN80944.1  A0A0H2V8P1  429 aa Hypothetical protein ybdN n.s. ●●○○○ -1.72 -1.72122235262092
Escherichia coli CFT073  c2539  AAN80993.1  A0A0H2VAY0  sbcB  491 aa Exodeoxyribonuclease I n.s. ●●○○○ -1.72 -1.72092897230388
Escherichia coli CFT073  c2188  AAN80647.1  P0ACY4  yeaG  644 aa Hypothetical protein yeaG n.s. ●●○○○ -1.72 -1.72084499049154
Escherichia coli CFT073  c2824  AAN81278.1  Q8FFJ9  nuoG  910 aa NADH dehydrogenase I chain G n.s. ●●○○○ -1.72 -1.72066151167527
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4290  CBW20376.1  A0A0H3NIR1  yjeF  515 aa conserved hypothetical protein n.s. ●●○○○ -1.72 -1.72051201207281
Escherichia coli CFT073  c2145  AAN80604.1  Q8FH02  astB  447 aa Succinylarginine dihydrolase n.s. ●●○○○ -1.72 -1.72033961030319
Serratia marcescens Strain UMH9  BVG96_01875  ASL96431.1  232 aa 7-cyano-7-deazaguanine synthase n.s. ●●○○○ -1.72 -1.71760561406718
Escherichia coli CFT073  c2024  AAN80484.1  Q8FH92  rsxE  231 aa Electron transport complex protein rnfE n.s. ●●○○○ -1.72 -1.7175902008091
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3511  CBW19605.1  A0A0H3NH24  yhhX  345 aa hypothetical oxidoreductase n.s. ●●○○○ -1.72 -1.71741107652819
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0820  CBW16917.1  A0A0H3N9X0  pflE  299 aa hypothetical pyruvate formate-lyase 3 activating enzyme n.s. ●●○○○ -1.72 -1.71702969907854
Serratia marcescens Strain UMH9  BVG96_01680  ASL96392.1  374 aa tRNA-guanine(34) transglycosylase n.s. ●●○○○ -1.72 -1.71689825313138
Serratia marcescens Strain UMH9  BVG96_13300  ASM00542.1  912 aa NADH-quinone oxidoreductase subunit G n.s. ●●○○○ -1.72 -1.71599363000087
Escherichia coli CFT073  c3033  AAN81483.1  Q8FF59  der  503 aa Probable GTP-binding protein engA n.s. ●●○○○ -1.71 -1.71460657654025
Escherichia coli CFT073  c2480  AAN80939.1  A0A0H2V8N6  40 aa Hypothetical protein n.s. ●●○○○ -1.71 -1.71424853718861
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2423  AIK81020.1  151 aa RNA polymerase-binding protein DksA n.s. ●●○○○ -1.71 -1.71376177191921
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2256  CBW18358.1  A0A0H3NDL6  sseL  317 aa Type III secretion system effector protein, deubiquitinase n.s. ●●○○○ -1.71 -1.71336653441469
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1530  AIK80150.1  183 aa hypothetical protein n.s. ●●○○○ -1.71 -1.7129653267654
Escherichia coli CFT073  c2312  AAN80771.1  A0A0H2V836  araH  329 aa High-affinity L-arabinose transport system; membrane protein, fragment 1 n.s. ●●○○○ -1.71 -1.71269185823684
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1784  CBW17878.1  A0A0H3NDT2  sopE2  240 aa Type III secretion system effector protein-causes membrane ruffling and disrupts tight junctions n.s. ●●○○○ -1.71 -1.71158566998087
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3328  CBW19424.1  A0A0H3NSI1  422 aa possible membrane transport protein n.s. ●●○○○ -1.71 -1.71117751268005
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3844  CBW19935.1  A0A0H3NNB2  asnA  330 aa asparagine synthetase A n.s. ●●○○○ -1.71 -1.70977621379908
Streptococcus pyogenes M1 5448  SP5448_05260  WP_010922305.1  325 aa nucleoid-associated protein n.s. ●●○○○ -1.71 -1.70943285187824
Streptococcus pyogenes M1 5448  SP5448_05840  WP_010922234.1  54 aa hypothetical protein n.s. ●●○○○ -1.71 -1.70847151538018
Streptococcus pyogenes M1 5448  SP5448_05840  WP_002991975.1  289 aa ABC transporter permease n.s. ●●○○○ -1.71 -1.70847151538018
Vibrio parahaemolyticus RIMD 2210633  VPA_0424  BAC61767.1  Q87J29  137 aa TonB system transport protein ExbD1 n.s. ●●○○○ -1.71 -1.70724421896531
Serratia marcescens Strain UMH9  BVG96_22560  ASM00220.1  640 aa DEAD/DEAH family ATP-dependent RNA helicase n.s. ●●○○○ -1.71 -1.7070753165773
Escherichia coli CFT073  c2011  AAN80471.1  A0A0H2V7R9  hdhA  255 aa 7-alpha-hydroxysteroid dehydrogenase n.s. ●●○○○ -1.71 -1.70614579044788
Vibrio parahaemolyticus RIMD 2210633  VP_0651  BAC58914.1  Q87RX5  grpE  198 aa GrpE n.s. ●●○○○ -1.71 -1.70601265279634
Escherichia coli CFT073  c1995  AAN80455.1  A0A0H2V7Q9  pntA  528 aa NAD(P) transhydrogenase subunit alpha n.s. ●●○○○ -1.71 -1.70506989964971
Escherichia coli CFT073  c1690  AAN80157.1  A0A0H2V843  338 aa Hypothetical protein ybjS n.s. ●●○○○ -1.7 -1.70347785408975
Retrieved entries 7,801–7,900 out of 36,363 total in 9.8 ms (Link to these results)