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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2702  AIK81292.1  88 aa hypothetical protein 4.4e-5 ●○○○○ -0.08 -0.0837434085307747
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4073  AIK82620.1  869 aa type VII secretion system (T7SS), usher family protein 1.3e-12 ●○○○○ -0.08 -0.0828070013220868
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2978  AIK81563.1  506 aa ABC transporter family protein 1.6e-10 ●○○○○ -0.08 -0.0822048223166335
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1572  AIK80192.1  80 aa specificity factor for ClpA-ClpP chaperone-protease complex 0.0011 ●○○○○ -0.08 -0.0820860097806792
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1947  AIK80554.1  418 aa mechanosensitive ion channel family protein 1.1e-5 ●○○○○ -0.08 -0.0812385081035838
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3652  AIK82207.1  425 aa branched-chain amino acid transport system / permease component family protein <1e-323 ●○○○○ -0.08 -0.0810207956663028
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2584  AIK81181.1  645 aa soluble lytic murein transglycosylase <1e-323 ●○○○○ -0.08 -0.0807717803932805
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4866  AIK83393.1  392 aa glycerol-3-phosphate dehydrogenase, anaerobic, Csubunit <1e-323 ●○○○○ -0.08 -0.0805431763675176
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3938  AIK82486.1  328 aa glutathione S-transferase, C-terminal domain protein <1e-323 ●○○○○ -0.08 -0.0801779795245427
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3723  AIK82278.1  196 aa major Facilitator Superfamily protein <1e-323 ●○○○○ -0.08 -0.0791563205886169
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4078  AIK82624.1  712 aa orn/Lys/Arg decarboxylase, N-terminal domain protein <1e-323 ●○○○○ -0.08 -0.075750233620096
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3430  AIK81987.1  215 aa bacterial regulatory, tetR family protein 3.6e-12 ●○○○○ -0.08 -0.0752324037527843
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2762  AIK81352.1  67 aa prophage CP4-57 regulatory family protein 0.032 ●○○○○ -0.07 -0.0744503004187099
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4150  AIK82696.1  669 aa cytochrome C biogenesis transmembrane region family protein 9.9e-13 ●○○○○ -0.07 -0.0740255507679411
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5000  AIK83526.1  412 aa efflux transporter, RND family, MFP subunit 0.00044 ●○○○○ -0.07 -0.0738869360778529
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4822  AIK83349.1  120 aa dihydroneopterin triphosphate 2'-epimerase 6.0e-5 ●○○○○ -0.07 -0.0724690521491209
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4185  AIK82730.1  203 aa ABC transporter family protein 0.00039 ●○○○○ -0.07 -0.0720519028284021
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2745  AIK81335.1  161 aa hypothetical protein 0.017 ●○○○○ -0.07 -0.0712182044657284
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2191  AIK80796.1  294 aa nucleoside-specific channel-forming, Tsx familyprotein <1e-323 ●○○○○ -0.07 -0.0711474655886627
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1974  AIK80580.1  555 aa bacterial extracellular solute-binding, 5 Middlefamily protein 0.00036 ●○○○○ -0.07 -0.0704679593399888
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4892  AIK83419.1  544 aa malate dehydrogenase 3.4e-11 ●○○○○ -0.07 -0.0667633642703184
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3238  AIK81799.1  302 aa bacterial regulatory helix-turn-helix, lysR family protein <1e-323 ●○○○○ -0.07 -0.0662068893613875
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2871  AIK81460.1  397 aa sugar (and other) transporter family protein 0.0059 ●○○○○ -0.06 -0.0649947968548307
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2427  AIK81024.1  263 aa 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.001 ●○○○○ -0.06 -0.0632301694823564
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3623  AIK82178.1  379 aa UDP-L-Ara4O C-4' transaminase 1.8e-9 ●○○○○ -0.06 -0.0628648482876334
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4856  AIK83383.1  321 aa o-succinylbenzoate synthase 3.2e-5 ●○○○○ -0.06 -0.0623356734397109
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3378  AIK81934.1  553 aa aspT/YidE/YbjL antiporter duplication domain protein 3.6e-10 ●○○○○ -0.06 -0.0622908221935512
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1737  AIK80357.1  241 aa histidine utilization repressor 0.034 ●○○○○ -0.06 -0.0612230629521986
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4281  AIK82826.1  346 aa aldo/keto reductase family protein 4.4e-5 ●○○○○ -0.06 -0.0609277512653605
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2242  AIK80847.1  283 aa tauD <1e-323 ●○○○○ -0.06 -0.0608837352943099
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2943  AIK81528.1  324 aa hypothetical protein <1e-323 ●○○○○ -0.06 -0.0599626157266952
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2310  AIK80914.1  482 aa succinate-semialdehyde dehydrogenase family protein <1e-323 ●○○○○ -0.06 -0.0597088223497702
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2925  AIK81511.1  180 aa fimbrial family protein 0.0028 ●○○○○ -0.06 -0.0594886286599438
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3528  AIK82084.1  635 aa mtlA <1e-323 ●○○○○ -0.06 -0.0593834211201144
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3738  AIK82293.1  601 aa proton antiporter-2 family protein <1e-323 ●○○○○ -0.06 -0.0590349260927847
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4977  AIK83503.1  350 aa fructose bisphosphate aldolase 0.0045 ●○○○○ -0.06 -0.0570935026569861
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3855  AIK82405.1  427 aa sugar (and other) transporter family protein <1e-323 ●○○○○ -0.06 -0.0556400086940039
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3417  AIK81974.1  237 aa 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase <1e-323 ●○○○○ -0.06 -0.0553263668864108
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3273  AIK81834.1  421 aa lacY lactose MFS transporter <1e-323 ●○○○○ -0.05 -0.0545477714720238
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3684  AIK82239.1  754 aa glycogen/starch/alpha-glucan phosphorylases family protein <1e-323 ●○○○○ -0.05 -0.0545439956407039
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4732  AIK83266.1  299 aa coproporphyrinogen III oxidase family protein <1e-323 ●○○○○ -0.05 -0.0541446441235979
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4348  AIK82891.1  273 aa hypothetical protein <1e-323 ●○○○○ -0.05 -0.0540654630280018
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1709  AIK80329.1  579 aa heme ABC exporter, ATP-binding protein CcmA 0.0031 ●○○○○ -0.05 -0.052826710301294
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3022  AIK81607.1  752 aa tonB-dependent siderophore receptor family protein <1e-323 ●○○○○ -0.05 -0.0511230582197472
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4937  AIK83463.1  336 aa branched-chain amino acid transport system / permease component family protein <1e-323 ●○○○○ -0.05 -0.0491779611060868
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3371  AIK81928.1  408 aa hypothetical protein 6.7e-7 ●○○○○ -0.05 -0.0484107840014198
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1997  AIK80603.1  326 aa alanine racemase 6.2e-5 ●○○○○ -0.05 -0.0460359956188738
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2015  AIK80621.1  395 aa anaerobic sulfatase maturase 1.2e-5 ●○○○○ -0.05 -0.0459859629622049
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2807  AIK81396.1  311 aa aspartate carbamoyltransferase 0.00034 ●○○○○ -0.05 -0.0450686936067384
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3814  AIK82364.1  202 aa conserved inner membrane protein 1.4e-8 ●○○○○ -0.04 -0.0449394469929967
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2689  AIK81283.1  335 aa tryptophan--tRNA ligase 0.00037 ●○○○○ -0.04 -0.0447187403654554
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2790  AIK81379.1  500 aa putative ATPase 8.2e-10 ●○○○○ -0.04 -0.0442058182296828
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3956  AIK82504.1  235 aa B3/4 domain protein 1.2e-11 ●○○○○ -0.04 -0.0438953564498802
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3568  AIK82123.1  526 aa dppA <1e-323 ●○○○○ -0.04 -0.0438274192855628
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1761  AIK80381.1  262 aa molybdenum-pterin binding domain protein 1.2e-15 ●○○○○ -0.04 -0.0434687229622021
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2250  AIK80855.1  258 aa ethanolamine ammonia-lyase light chain family protein 0.022 ●○○○○ -0.04 -0.0427231190383312
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3659  AIK82214.1  281 aa ugpE 1.2e-12 ●○○○○ -0.04 -0.0423090857194523
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1808  AIK80421.1  310 aa hypothetical protein 0.0014 ●○○○○ -0.04 -0.0411819329652778
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4585  AIK83123.1  857 aa ATP-dependent chaperone protein ClpB <1e-323 ●○○○○ -0.04 -0.0406443982060731
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2447  AIK81044.1  482 aa hypothetical protein 3.1e-9 ●○○○○ -0.04 -0.0377365236109622
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3973  AIK82521.1  356 aa dihydroxyacetone kinase, DhaK subunit <1e-323 ●○○○○ -0.04 -0.0377212178234582
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1459  AIK80080.1  495 aa gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase 1.6e-5 ●○○○○ -0.04 -0.0365552783671987
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3904  AIK82452.1  314 aa tRNA pseudouridine(55) synthase 3.2e-13 ●○○○○ -0.04 -0.0361153310666752
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3102  AIK81683.1  256 aa thiazole biosynthesis ThiG family protein 0.0028 ●○○○○ -0.03 -0.0348327378039716
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4260  AIK82804.1  453 aa MFS transporter, sugar porter family protein 1.0e-8 ●○○○○ -0.03 -0.0312511995459907
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3788  AIK82343.1  157 aa hypothetical protein 9.8e-9 ●○○○○ -0.03 -0.0311600969745086
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2237  AIK80842.1  406 aa ABC transporter transmembrane region 2 family protein <1e-323 ●○○○○ -0.03 -0.0307139913312557
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3404  AIK81961.1  337 aa 2-aminoethylphosphonate ABC transporter, 2-aminoethylphosphonate binding protein 0.0002 ●○○○○ -0.03 -0.0295749119014405
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2068  AIK80673.1  99 aa hypothetical protein 3.4e-5 ●○○○○ -0.03 -0.0284846222723155
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3291  AIK81852.1  286 aa yihY family inner membrane domain protein <1e-323 ●○○○○ -0.03 -0.0280314686907477
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2848  AIK81437.1  577 aa outer membrane protein <1e-323 ●○○○○ -0.03 -0.0278232137461045
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2503  AIK81100.1  394 aa yabM MFS transporter 2.2e-16 ●○○○○ -0.03 -0.0274687322384768
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4535  AIK83073.1  845 aa type VII secretion system (T7SS), usher family protein <1e-323 ●○○○○ -0.03 -0.0257811736798291
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2974  AIK81559.1  187 aa phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN <1e-323 ●○○○○ -0.03 -0.0250319260835075
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2436  AIK81033.1  39 aa hypothetical protein 0.039 ●○○○○ -0.02 -0.0248876242274035
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4626  AIK83160.1  140 aa SURF4 family protein 0.026 ●○○○○ -0.02 -0.0247460686317799
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3406  AIK81963.1  286 aa 2-aminoethylphosphonate ABC transporter, permease protein <1e-323 ●○○○○ -0.02 -0.0231345277969789
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2103  AIK80708.1  1115 aa kefA <1e-323 ●○○○○ -0.02 -0.023034800513668
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4357  AIK82900.1  472 aa L-fuculokinase <1e-323 ●○○○○ -0.02 -0.0224424400132681
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4938  AIK83464.1  238 aa hypothetical protein 4.1e-5 ●○○○○ -0.02 -0.0222883236493597
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2434  AIK81031.1  220 aa carbonic anhydrase 2 <1e-323 ●○○○○ -0.02 -0.0216484460471514
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3473  AIK82029.1  558 aa DNA ligase <1e-323 ●○○○○ -0.02 -0.0215602583651655
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3321  AIK81878.1  622 aa potassium uptake protein <1e-323 ●○○○○ -0.02 -0.0187401417738499
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3927  AIK82475.1  443 aa D-galactonate transporter family protein <1e-323 ●○○○○ -0.02 -0.0183846665034409
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1664  AIK80284.1  513 aa bacterial extracellular solute-binding, 5 Middlefamily protein 0.0021 ●○○○○ -0.02 -0.0183097205619778
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2457  AIK81054.1  316 aa alpha-N-arabinofuranosidase 2 <1e-323 ●○○○○ -0.02 -0.0180929083335498
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2656  AIK81250.1  265 aa 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 0.00051 ●○○○○ -0.02 -0.0167644709142078
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4303  AIK82848.1  404 aa acetate kinase 7.8e-6 ●○○○○ -0.02 -0.0164475719883965
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4302  AIK82847.1  300 aa GHMP kinase N terminal domain protein 1.5e-6 ●○○○○ -0.02 -0.0151612189095803
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3319  AIK81876.1  501 aa heme ABC exporter, ATP-binding protein CcmA <1e-323 ●○○○○ -0.01 -0.014179002997182
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3387  AIK81944.1  394 aa sugar (and other) transporter family protein 8.2e-13 ●○○○○ -0.01 -0.0140086855696495
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2210  AIK80816.1  605 aa alpha amylase, catalytic domain protein 4.8e-7 ●○○○○ -0.01 -0.0134471275876055
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3441  AIK81999.1  349 aa putative oxidoreductase, Zn-dependent and NAD(P)-binding protein <1e-323 ●○○○○ -0.01 -0.0126477828369356
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2029  AIK80635.1  380 aa hlyD secretion family protein 0.00069 ●○○○○ -0.01 -0.0121898206462858
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2233  AIK80838.1  365 aa D-alanine-D-alanine ligase A 2.8e-9 ●○○○○ -0.01 -0.0113084922955539
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3736  AIK82291.1  634 aa yheS <1e-323 ●○○○○ -0.01 -0.0101329999535871
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3380  AIK81937.1  440 aa 6-phospho-alpha-glucosidase <1e-323 ●○○○○ -0.01 -0.00871943090992343
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4637  AIK83171.1  244 aa tRNA:Cm32/Um32 methyltransferase 0.0046 ●○○○○ -0.01 -0.00702228671923443
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3396  AIK81953.1  463 aa phosphoglycerate transporter family protein <1e-323 ●○○○○ -0.01 -0.00680676727618392
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3692  AIK82247.1  772 aa ferrous iron transport protein B <1e-323 ●○○○○ -0.01 -0.00671524333910065
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