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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_06565  ATI05407.1  363 aa redox-regulated ATPase YchF n.s. ●●○○○ -1.4 -1.40138476648088
Escherichia coli M12  CO715_21015  ATI07990.1  119 aa histidine triad nucleotide-binding protein n.s. ●●○○○ -1.39 -1.38782277555471
Escherichia coli M12  CO715_09150  ATI05862.1  421 aa cell envelope integrity protein TolA n.s. ●●○○○ -1.37 -1.3711310944148
Escherichia coli M12  CO715_17120  ATI07286.1  107 aa hypothetical protein n.s. ●●○○○ -1.37 -1.36925328028656
Escherichia coli M12  CO715_08335  ATI05719.1  74 aa cold-shock protein CspD n.s. ●●○○○ -1.35 -1.3523529531324
Escherichia coli M12  CO715_08430  ATI05735.1  171 aa lipoprotein n.s. ●●○○○ -1.35 -1.34546763466219
Escherichia coli M12  CO715_20270  ATI07852.1  52 aa hypothetical protein n.s. ●●○○○ -1.34 -1.33691314807799
Escherichia coli M12  CO715_01780  ATI04571.1  185 aa ribose 1,5-bisphosphokinase n.s. ●●○○○ -1.33 -1.32606355533705
Escherichia coli M12  CO715_03435  ATI04872.1  182 aa elongation factor P hydroxylase n.s. ●●○○○ -1.31 -1.31396208651061
Escherichia coli M12  CO715_00065  ATI04268.1  616 aa molecular chaperone HscA n.s. ●●○○○ -1.31 -1.31396208651061
Escherichia coli M12  CO715_20940  ATI07975.1  173 aa 23S rRNA accumulation protein YceD n.s. ●●○○○ -1.31 -1.3062421839834
Escherichia coli M12  CO715_22150  ATI08194.1  673 aa DNA helicase Rep n.s. ●●○○○ -1.29 -1.28746404270101
Escherichia coli M12  CO715_04405  ATI05048.1  46 aa cobalamin biosynthesis protein n.s. ●●○○○ -1.28 -1.28162195430204
Escherichia coli M12  CO715_08275  ATI05710.1  164 aa leucine-responsive regulatory protein n.s. ●●○○○ -1.27 -1.27223288366084
Escherichia coli M12  CO715_04175  ATI05011.1  72 aa protein SlyX n.s. ●●○○○ -1.27 -1.26534756519063
Escherichia coli M12  CO715_14745  ATI06860.1  45 aa DUF4753 domain-containing protein n.s. ●●○○○ -1.26 -1.26388704309089
Escherichia coli M12  CO715_03585  ATI04901.1  714 aa phosphate acetyltransferase n.s. ●●○○○ -1.26 -1.26367839707664
Escherichia coli M12  CO715_10755  ATI06134.1  101 aa monooxygenase n.s. ●●○○○ -1.25 -1.2511596362217
Escherichia coli M12  CO715_16905  ATI07247.1  257 aa transcriptional regulator n.s. ●●○○○ -1.24 -1.24490025579424
Escherichia coli M12  CO715_15780  ATI07040.1  235 aa DUF484 domain-containing protein n.s. ●●○○○ -1.24 -1.23738899928128
Escherichia coli M12  CO715_09725  ATI05962.1  213 aa octanoyltransferase n.s. ●●○○○ -1.23 -1.23342472501055
Escherichia coli M12  CO715_04220  ATI05020.1  394 aa translation elongation factor EF-Tu 2 n.s. ●●○○○ -1.23 -1.23154691088231
Escherichia coli M12  CO715_13950  ATI06711.1  271 aa methionine ABC transporter substrate-binding protein MetQ n.s. ●●○○○ -1.23 -1.22904315871133
Escherichia coli M12  CO715_06070  ATI05322.1  119 aa DUF4186 domain-containing protein n.s. ●●○○○ -1.22 -1.21715033589914
Escherichia coli M12  CO715_04530  ATI05069.1  319 aa AraC family transcriptional regulator n.s. ●●○○○ -1.21 -1.21172553952867
Escherichia coli M12  CO715_20985  ATI07984.1  340 aa cell division protein YceG n.s. ●●○○○ -1.2 -1.19962407070224
Escherichia coli M12  CO715_19400  ATI07692.1  185 aa transcriptional regulator n.s. ●●○○○ -1.19 -1.18814853991855
Escherichia coli M12  CO715_07190  ATI05520.1  71 aa hypothetical protein n.s. ●●○○○ -1.19 -1.18731395586155
Escherichia coli M12  CO715_15540  ATI06999.1  386 aa cystathionine gamma-synthase n.s. ●●○○○ -1.17 -1.17062227472164
Escherichia coli M12  CO715_09500  ATI05926.1  382 aa N-acetylglucosamine-6-phosphate deacetylase n.s. ●●○○○ -1.17 -1.16895310660765
Escherichia coli M12  CO715_09445  ATI05916.1  181 aa replication initiation regulator SeqA n.s. ●●○○○ -1.16 -1.16498883233693
Escherichia coli M12  CO715_00060  ATI04267.1  171 aa co-chaperone protein HscB n.s. ●●○○○ -1.16 -1.16311101820869
Escherichia coli M12  CO715_19900  ATI07781.1  112 aa nitrogen regulatory protein P-II 2 n.s. ●●○○○ -1.15 -1.14954902728251
Escherichia coli M12  CO715_00590  ATI04364.1  219 aa lipoprotein n.s. ●●○○○ -1.14 -1.1422464167838
Escherichia coli M12  CO715_00175  ATI04288.1  525 aa GMP synthase (glutamine-hydrolyzing) n.s. ●●○○○ -1.12 -1.12367692151565
Escherichia coli M12  CO715_23975  ATI08496.1  64 aa bacterioferritin-associated ferredoxin n.s. ●●○○○ -1.11 -1.10865440848973
Escherichia coli M12  CO715_04125  ATI05001.1  134 aa hypothetical protein n.s. ●●○○○ -1.1 -1.09843075379154
Escherichia coli M12  CO715_07970  ATI05653.1  173 aa metal-dependent hydrolase n.s. ●●○○○ -1.1 -1.0965529396633
Escherichia coli M12  CO715_02375  ATI04680.1  374 aa glycosyltransferase family 1 protein n.s. ●●○○○ -1.08 -1.08257365670862
Escherichia coli M12  CO715_00230  ATI04299.1  226 aa ribonuclease 3 n.s. ●●○○○ -1.04 -1.03938393175911
Escherichia coli M12  CO715_00215  ATI04296.1  599 aa elongation factor 4 n.s. ●●○○○ -1 -1.00224494122281
Escherichia coli M12  CO715_07115  ATI05506.1  93 aa hypothetical protein n.s. ●○○○○ -0.99 -0.99369045463861
Escherichia coli M12  CO715_08955  ATI05833.1  158 aa kinase inhibitor n.s. ●○○○○ -0.99 -0.990352118410628
Escherichia coli M12  CO715_19680  ATI07743.1  132 aa acyl-CoA thioesterase n.s. ●○○○○ -0.99 -0.987639720225393
Escherichia coli M12  CO715_11705  ATI06311.1  217 aa 3,4-dihydroxy-2-butanone-4-phosphate synthase n.s. ●○○○○ -0.98 -0.976164189441706
Escherichia coli M12  CO715_11215  ATI06221.1  182 aa hypothetical protein n.s. ●○○○○ -0.96 -0.963645428586774
Escherichia coli M12  CO715_21260  ATI08032.1  185 aa thiol:disulfide interchange protein n.s. ●○○○○ -0.94 -0.944867287304376
Escherichia coli M12  CO715_06190  ATI05344.1  63 aa hypothetical protein n.s. ●○○○○ -0.94 -0.943615411218883
Escherichia coli M12  CO715_15775  ATI07039.1  274 aa diaminopimelate epimerase n.s. ●○○○○ -0.93 -0.930262066306956
Escherichia coli M12  CO715_10445  ATI08785.1  309 aa DNA replication terminus site-binding protein n.s. ●○○○○ -0.93 -0.927966960150219
Escherichia coli M12  CO715_13330  ATI06604.1  293 aa 50S ribosomal protein L11 methyltransferase n.s. ●○○○○ -0.91 -0.912527155095803
Escherichia coli M12  CO715_22220  ATI08208.1  224 aa dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase n.s. ●○○○○ -0.91 -0.910649340967563
Escherichia coli M12  CO715_15265  ATI06953.1  145 aa D-aminoacyl-tRNA deacylase n.s. ●○○○○ -0.9 -0.900842978297866
Escherichia coli M12  CO715_00010  ATI04257.1  296 aa transcriptional regulator n.s. ●○○○○ -0.9 -0.898547872141129
Escherichia coli M12  CO715_21295  ATI08037.1  586 aa hypothetical protein n.s. ●○○○○ -0.89 -0.893957659827654
Escherichia coli M12  CO715_13720  ATI06670.1  128 aa reactive intermediate/imine deaminase n.s. ●○○○○ -0.87 -0.870589306231782
Escherichia coli M12  CO715_12610  ATI06473.1  114 aa transcriptional regulator n.s. ●○○○○ -0.86 -0.860782943562085
Escherichia coli M12  CO715_15945  ATI07071.1  233 aa NAD(P)H-flavin reductase n.s. ●○○○○ -0.86 -0.855775439220113
Escherichia coli M12  CO715_10565  ATI06101.1  231 aa electron transporter RsxE n.s. ●○○○○ -0.84 -0.840961572208443
Escherichia coli M12  CO715_05015  ATI05149.1  245 aa 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase n.s. ●○○○○ -0.84 -0.836371359894968
Escherichia coli M12  CO715_09570  ATI05933.1  391 aa 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase n.s. ●○○○○ -0.83 -0.833867607723982
Escherichia coli M12  CO715_18545  ATI07538.1  226 aa integrase n.s. ●○○○○ -0.83 -0.825730413168277
Escherichia coli M12  CO715_18340  ATI07504.1  197 aa non-canonical purine NTP pyrophosphatase n.s. ●○○○○ -0.82 -0.820514262812055
Escherichia coli M12  CO715_01010  ATI04435.1  241 aa phosphate transport system regulator PhoU n.s. ●○○○○ -0.81 -0.81404623637034
Escherichia coli M12  CO715_02915  ATI08713.1  299 aa coproporphyrinogen III oxidase n.s. ●○○○○ -0.81 -0.812585714270598
Escherichia coli M12  CO715_14665  ATI06844.1  185 aa protein DcrB n.s. ●○○○○ -0.79 -0.789426006688975
Escherichia coli M12  CO715_24535  ATI08598.1  152 aa xanthine phosphoribosyltransferase n.s. ●○○○○ -0.79 -0.789217360674726
Escherichia coli M12  CO715_01265  ATI04481.1  251 aa transcriptional regulator n.s. ●○○○○ -0.76 -0.758546396580143
Escherichia coli M12  CO715_00570  ATI04360.1  70 aa cold-shock protein n.s. ●○○○○ -0.76 -0.755625352380659
Escherichia coli M12  CO715_16255  ATI07128.1  306 aa D-alanine--D-alanine ligase B n.s. ●○○○○ -0.75 -0.753330246223922
Escherichia coli M12  CO715_11760  ATI06321.1  209 aa ADP-ribose diphosphatase n.s. ●○○○○ -0.75 -0.748322741881949
Escherichia coli M12  CO715_08830  ATI05809.1  160 aa DUF1768 domain-containing protein n.s. ●○○○○ -0.74 -0.737681795155257
Escherichia coli M12  CO715_12785  ATI06506.1  167 aa N-acetyltransferase n.s. ●○○○○ -0.73 -0.731005122699294
Escherichia coli M12  CO715_12925  ATI06531.1  158 aa transcription elongation factor GreA n.s. ●○○○○ -0.73 -0.725580326328823
Escherichia coli M12  CO715_12425  ATI06440.1  104 aa mRNA interferase HigB n.s. ●○○○○ -0.73 -0.725580326328823
Escherichia coli M12  CO715_02885  ATI04774.1  467 aa ethanolamine ammonia-lyase reactivating factor EutA n.s. ●○○○○ -0.72 -0.72057282198685
Escherichia coli M12  CO715_11055  ATI06191.1  96 aa hypothetical protein n.s. ●○○○○ -0.72 -0.71514802561638
Escherichia coli M12  CO715_19555  ATI07723.1  324 aa LysR family transcriptional regulator CysB n.s. ●○○○○ -0.71 -0.709305937217412
Escherichia coli M12  CO715_14230  ATI06762.1  151 aa RNA polymerase-binding transcription factor DksA n.s. ●○○○○ -0.71 -0.707010831060675
Escherichia coli M12  CO715_19195  ATI07655.1  140 aa heat-inducible protein n.s. ●○○○○ -0.7 -0.704507078889688
Escherichia coli M12  CO715_21965  ATI08161.1  147 aa low molecular weight protein-tyrosine-phosphatase Wzb n.s. ●○○○○ -0.7 -0.700125512590462
Escherichia coli M12  CO715_23980  ATI08497.1  158 aa bacterioferritin n.s. ●○○○○ -0.69 -0.691988318034756
Escherichia coli M12  CO715_16595  ATI07192.1  149 aa peptidylprolyl isomerase n.s. ●○○○○ -0.69 -0.689693211878019
Escherichia coli M12  CO715_10560  ATI06100.1  206 aa electron transport complex subunit G n.s. ●○○○○ -0.68 -0.679260911165576
Escherichia coli M12  CO715_22015  ATI08171.1  159 aa GDP-mannose mannosyl hydrolase n.s. ●○○○○ -0.64 -0.643165150700523
Escherichia coli M12  CO715_18140  ATI07468.1  359 aa class II fructose-bisphosphate aldolase n.s. ●○○○○ -0.64 -0.64191327461503
Escherichia coli M12  CO715_11655  ATI06302.1  412 aa multifunctional CCA tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase n.s. ●○○○○ -0.62 -0.622717841304135
Escherichia coli M12  CO715_21270  ATI08034.1  215 aa DNA-binding response regulator n.s. ●○○○○ -0.61 -0.611242310520447
Escherichia coli M12  CO715_09420  ATI05911.1  190 aa potassium-transporting ATPase subunit C n.s. ●○○○○ -0.61 -0.611033664506198
Escherichia coli M12  CO715_12505  ATI06453.1  122 aa hypothetical protein n.s. ●○○○○ -0.61 -0.611033664506198
Escherichia coli M12  CO715_16070  ATI07094.1  256 aa inner membrane transport permease YadH n.s. ●○○○○ -0.61 -0.610407726463452
Escherichia coli M12  CO715_22835  ATI08899.1  164 aa DUF2501 family protein n.s. ●○○○○ -0.6 -0.604565638064483
Escherichia coli M12  CO715_09075  ATI05856.1  313 aa zinc transporter ZitB n.s. ●○○○○ -0.6 -0.599558133722511
Escherichia coli M12  CO715_14005  ATI06721.1  129 aa VOC family protein n.s. ●○○○○ -0.6 -0.597263027565774
Escherichia coli M12  CO715_12865  ATI06522.1  495 aa transcription termination protein NusA n.s. ●○○○○ -0.57 -0.574311965998399
Escherichia coli M12  CO715_11860  ATI06340.1  85 aa hypothetical protein n.s. ●○○○○ -0.57 -0.574311965998399
Escherichia coli M12  CO715_19095  ATI07636.1  57 aa hypothetical protein n.s. ●○○○○ -0.57 -0.56680070948544
Escherichia coli M12  CO715_01015  ATI04436.1  257 aa phosphate ABC transporter ATP-binding protein n.s. ●○○○○ -0.56 -0.558663514929734
Escherichia coli M12  CO715_20555  ATI07905.1  128 aa pyrimidine utilization protein C n.s. ●○○○○ -0.51 -0.514639205923224
Escherichia coli M12  CO715_12160  ATI06396.1  201 aa type II secretion system protein GspJ n.s. ●○○○○ -0.51 -0.511300869695243
Retrieved entries 2,001–2,100 out of 3,550 total in 48.9 ms (Link to these results)