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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_20835  ATI07954.1  511 aa lipid II flippase MurJ n.s. ●○○○○ -0.48 -0.483342303785895
Escherichia coli M12  CO715_06355  ATI05373.1  98 aa hypothetical protein n.s. ●○○○○ -0.47 -0.465190100546244
Escherichia coli M12  CO715_10805  ATI06143.1  78 aa murein lipoprotein n.s. ●○○○○ -0.46 -0.463312286418005
Escherichia coli M12  CO715_22775  ATI08302.1  137 aa DNA polymerase III subunit psi n.s. ●○○○○ -0.46 -0.462894994389507
Escherichia coli M12  CO715_02620  ATI04725.1  212 aa phosphoribosylglycinamide formyltransferase n.s. ●○○○○ -0.43 -0.428051110009947
Escherichia coli M12  CO715_13770  ATI06680.1  183 aa hypothetical protein n.s. ●○○○○ -0.42 -0.424921419796214
Escherichia coli M12  CO715_22540  ATI08261.1  638 aa molecular chaperone DnaK n.s. ●○○○○ -0.42 -0.424921419796214
Escherichia coli M12  CO715_01455  ATI04513.1  131 aa fumarate reductase subunit C n.s. ●○○○○ -0.42 -0.424921419796214
Escherichia coli M12  CO715_12560  ATI06464.1  436 aa hypothetical protein n.s. ●○○○○ -0.42 -0.424921419796214
Escherichia coli M12  CO715_00170  ATI04287.1  488 aa IMP dehydrogenase n.s. ●○○○○ -0.42 -0.424921419796214
Escherichia coli M12  CO715_06800  ATI05448.1  57 aa hypothetical protein n.s. ●○○○○ -0.42 -0.422626313639477
Escherichia coli M12  CO715_07865  ATI08764.1  234 aa XRE family transcriptional regulator n.s. ●○○○○ -0.4 -0.400301190114848
Escherichia coli M12  CO715_02965  ATI04789.1  263 aa NAD(P)-dependent oxidoreductase n.s. ●○○○○ -0.38 -0.378602004632967
Escherichia coli M12  CO715_21300  ATI08038.1  75 aa hypothetical protein n.s. ●○○○○ -0.38 -0.378602004632967
Escherichia coli M12  CO715_08445  ATI05738.1  238 aa arginine transporter permease subunit ArtQ n.s. ●○○○○ -0.38 -0.377558774561722
Escherichia coli M12  CO715_09475  ATI05921.1  108 aa hypothetical protein n.s. ●○○○○ -0.38 -0.377558774561722
Escherichia coli M12  CO715_03090  ATI04810.1  114 aa hypothetical protein n.s. ●○○○○ -0.38 -0.376306898476229
Escherichia coli M12  CO715_04135  ATI05003.1  72 aa hypothetical protein n.s. ●○○○○ -0.36 -0.355650943065592
Escherichia coli M12  CO715_16075  ATI07095.1  308 aa multidrug ABC transporter ATP-binding protein n.s. ●○○○○ -0.35 -0.351269376766366
Escherichia coli M12  CO715_10850  ATI06152.1  136 aa thioesterase n.s. ●○○○○ -0.35 -0.350226146695122
Escherichia coli M12  CO715_17530  ATI07361.1  176 aa RNA pyrophosphohydrolase n.s. ●○○○○ -0.35 -0.350226146695122
Escherichia coli M12  CO715_18005  ATI07445.1  364 aa aminomethyltransferase n.s. ●○○○○ -0.34 -0.336038217726199
Escherichia coli M12  CO715_02275  ATI04660.1  155 aa protein-export protein SecB n.s. ●○○○○ -0.32 -0.323728102885516
Escherichia coli M12  CO715_00220  ATI04297.1  324 aa S26 family signal peptidase n.s. ●○○○○ -0.32 -0.323728102885516
Escherichia coli M12  CO715_11395  ATI06256.1  50 aa hypothetical protein n.s. ●○○○○ -0.32 -0.322267580785774
Escherichia coli M12  CO715_13040  ATI06551.1  95 aa ribosome hibernation promoting factor n.s. ●○○○○ -0.32 -0.321850288757277
Escherichia coli M12  CO715_07590  ATI05590.1  217 aa formate dehydrogenase cytochrome b556 subunit n.s. ●○○○○ -0.32 -0.321641642743028
Escherichia coli M12  CO715_15455  ATI06986.1  248 aa ferredoxin--NADP(+) reductase n.s. ●○○○○ -0.3 -0.299942457261146
Escherichia coli M12  CO715_03525  ATI04889.1  260 aa histidine ABC transporter substrate-binding protein HisJ n.s. ●○○○○ -0.27 -0.273235767437292
Escherichia coli M12  CO715_20730  ATI07934.1  43 aa hypothetical protein n.s. ●○○○○ -0.26 -0.262803466724849
Escherichia coli M12  CO715_07285  ATI05536.1  57 aa protein GnsA n.s. ●○○○○ -0.26 -0.256544086297383
Escherichia coli M12  CO715_16600  ATI07193.1  164 aa signal peptidase II n.s. ●○○○○ -0.26 -0.255083564197641
Escherichia coli M12  CO715_02650  ATI04731.1  119 aa oxidoreductase n.s. ●○○○○ -0.25 -0.254248980140646
Escherichia coli M12  CO715_00480  ATI04342.1  282 aa IclR family transcriptional regulator n.s. ●○○○○ -0.25 -0.249032829784424
Escherichia coli M12  CO715_22090  ATI08183.1  112 aa hypothetical protein n.s. ●○○○○ -0.22 -0.218361865689841
Escherichia coli M12  CO715_06510  ATI05398.1  269 aa protein sirB1 n.s. ●○○○○ -0.22 -0.216901343590099
Escherichia coli M12  CO715_07000  ATI05484.1  120 aa crossover junction endodeoxyribonuclease RusA n.s. ●○○○○ -0.22 -0.216275405547353
Escherichia coli M12  CO715_10400  ATI06072.1  462 aa NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta n.s. ●○○○○ -0.2 -0.202296122592679
Escherichia coli M12  CO715_07070  ATI05497.1  130 aa regulator n.s. ●○○○○ -0.19 -0.190403299780494
Escherichia coli M12  CO715_04880  ATI05125.1  367 aa phosphoporin PhoE n.s. ●○○○○ -0.19 -0.186439025509766
Escherichia coli M12  CO715_16115  ATI07102.1  120 aa hypothetical protein n.s. ●○○○○ -0.17 -0.168912760312861
Escherichia coli M12  CO715_00560  ATI04358.1  689 aa glycine--tRNA ligase subunit beta n.s. ●○○○○ -0.17 -0.168704114298612
Escherichia coli M12  CO715_06550  ATI05405.1  550 aa C4-dicarboxylic acid transporter DauA n.s. ●○○○○ -0.15 -0.152012433158704
Escherichia coli M12  CO715_03950  ATI04967.1  850 aa carboxypeptidase/penicillin-binding protein 1A n.s. ●○○○○ -0.14 -0.136363982090039
Escherichia coli M12  CO715_07360  ATI05547.1  219 aa BAX inhibitor protein n.s. ●○○○○ -0.13 -0.127809495505836
Escherichia coli M12  CO715_24645  ATI08616.1  120 aa hypothetical protein n.s. ●○○○○ -0.13 -0.126557619420342
Escherichia coli M12  CO715_13240  ATI06587.1  309 aa HTH-type transcriptional activator AaeR n.s. ●○○○○ -0.12 -0.120298238992877
Escherichia coli M12  CO715_02520  ATI04706.1  47 aa cytoplasmic protein n.s. ●○○○○ -0.12 -0.115082088636655
Escherichia coli M12  CO715_03165  ATI04823.1  244 aa DNA-binding response regulator n.s. ●○○○○ -0.1 -0.0950520712687644
Escherichia coli M12  CO715_11530  ATI06281.1  192 aa coenzyme A pyrophosphatase n.s. ●○○○○ -0.05 -0.0462289039345309
Escherichia coli M12  CO715_16700  ATI07211.1  134 aa DNA-binding protein StpA n.s. ●○○○○ -0.05 -0.0462289039345309
Escherichia coli M12  CO715_21810  ATI08133.1  284 aa tagatose-1,6-bisphosphate aldolase n.s. ●○○○○ -0.05 -0.0456029658917842
Escherichia coli M12  CO715_03035  ATI04803.1  671 aa DNA ligase (NAD(+)) LigA n.s. ●○○○○ -0.05 -0.0456029658917842
Escherichia coli M12  CO715_12700  ATI06489.1  377 aa N-acetylglucosamine-6-phosphate deacetylase n.s. ●○○○○ -0.03 -0.0312063909086128
Escherichia coli M12  CO715_01850  ATI04584.1  198 aa heme lysase NrfEFG subunit NrfG n.s. ●○○○○ -0.03 -0.0266161785951379
Escherichia coli M12  CO715_14775  ATI06866.1  438 aa ABC transporter substrate-binding protein n.s. ●○○○○ -0.01 -0.0132628336832108
Escherichia coli M12  CO715_17265  ATI07313.1  223 aa 7-carboxy-7-deazaguanine synthase QueE n.s. ●○○○○ -0.01 -0.0101331434694778
Escherichia coli M12  CO715_18890  ATI07600.1  94 aa hypothetical protein n.s. ●○○○○ -0.01 -0.00658616122724723
Escherichia coli M12  CO715_17100  ATI07282.1  349 aa tRNA pseudouridine(13) synthase TruD n.s. ●○○○○ -0 -0.00366511702776312
Escherichia coli M12  CO715_11440  ATI06264.1  82 aa GlsB/YeaQ/YmgE family stress response membrane protein n.s. ●○○○○ -0 -0.0030391789850166
Escherichia coli M12  CO715_19980  ATI07797.1  105 aa protein BolA n.s. ○○○○○ 0.01 0.00572395361343562
Escherichia coli M12  CO715_17880  ATI07421.1  259 aa oxidoreductase n.s. ○○○○○ 0.01 0.00572395361343562
Escherichia coli M12  CO715_15250  ATI06950.1  261 aa DeoR family transcriptional regulator n.s. ○○○○○ 0.01 0.00885364382716847
Escherichia coli M12  CO715_21380  ATI08053.1  488 aa mannitol dehydrogenase family protein n.s. ○○○○○ 0.02 0.0182427144683673
Escherichia coli M12  CO715_03965  ATI04970.1  146 aa DNA utilization protein HofO n.s. ○○○○○ 0.03 0.0272144930810683
Escherichia coli M12  CO715_11040  ATI06188.1  35 aa hypothetical protein n.s. ○○○○○ 0.03 0.0295095992378058
Escherichia coli M12  CO715_16055  ATI07091.1  126 aa aspartate 1-decarboxylase n.s. ○○○○○ 0.04 0.0386900238647557
Escherichia coli M12  CO715_21870  ATI08144.1  240 aa DNA-binding response regulator n.s. ○○○○○ 0.04 0.0395246079217511
Escherichia coli M12  CO715_04710  ATI05098.1  137 aa flagellar motor switch protein FliN n.s. ○○○○○ 0.04 0.0395246079217511
Escherichia coli M12  CO715_02055  ATI04621.1  290 aa 4-hydroxybenzoate octaprenyltransferase n.s. ○○○○○ 0.04 0.0395246079217511
Escherichia coli M12  CO715_13270  ATI06593.1  338 aa rod shape-determining protein MreC n.s. ○○○○○ 0.04 0.0401505459644977
Escherichia coli M12  CO715_21715  ATI08114.1  677 aa methionine--tRNA ligase n.s. ○○○○○ 0.04 0.0409851300214932
Escherichia coli M12  CO715_09290  ATI05888.1  115 aa succinate dehydrogenase hydrophobic membrane anchor subunit n.s. ○○○○○ 0.04 0.0409851300214932
Escherichia coli M12  CO715_06380  ATI05378.1  302 aa UTP--glucose-1-phosphate uridylyltransferase n.s. ○○○○○ 0.04 0.0420283600927375
Escherichia coli M12  CO715_21410  ATI08058.1  563 aa PTS fructose transporter subunit IIBC n.s. ○○○○○ 0.04 0.0447407582779726
Escherichia coli M12  CO715_05790  ATI05279.1  131 aa DNA-packaging protein FI n.s. ○○○○○ 0.08 0.0764549524437996
Escherichia coli M12  CO715_24725  ATI08630.1  194 aa molybdenum cofactor guanylyltransferase MobA n.s. ○○○○○ 0.08 0.0774981825150439
Escherichia coli M12  CO715_09250  ATI05881.1  301 aa LysR family transcriptional regulator n.s. ○○○○○ 0.08 0.0845921469995051
Escherichia coli M12  CO715_02425  ATI04689.1  198 aa nucleoid occlusion factor SlmA n.s. ○○○○○ 0.09 0.0850094390280029
Escherichia coli M12  CO715_22990  ATI08339.1  303 aa transcriptional regulator n.s. ○○○○○ 0.09 0.0870958991704914
Escherichia coli M12  CO715_08880  ATI05818.1  318 aa hypothetical protein n.s. ○○○○○ 0.13 0.125278119778033
Escherichia coli M12  CO715_07385  ATI05552.1  137 aa CoA-binding protein n.s. ○○○○○ 0.13 0.126947287892024
Escherichia coli M12  CO715_13630  ATI06654.1  360 aa LPS export ABC transporter permease LptG n.s. ○○○○○ 0.13 0.128407809991766
Escherichia coli M12  CO715_22355  ATI08231.1  440 aa MFS transporter n.s. ○○○○○ 0.15 0.149063765402403
Escherichia coli M12  CO715_07430  ATI05560.1  346 aa porin OmpA n.s. ○○○○○ 0.15 0.152193455616136
Escherichia coli M12  CO715_12120  ATI06389.1  136 aa hypothetical protein n.s. ○○○○○ 0.16 0.155949083872616
Escherichia coli M12  CO715_20090  ATI07818.1  156 aa 6,7-dimethyl-8-ribityllumazine synthase n.s. ○○○○○ 0.16 0.160747942200339
Escherichia coli M12  CO715_07150  ATI05513.1  153 aa NUDIX hydrolase n.s. ○○○○○ 0.16 0.160956588214588
Escherichia coli M12  CO715_07090  ATI05501.1  138 aa Host-nuclease inhibitor protein gam n.s. ○○○○○ 0.17 0.172223472984027
Escherichia coli M12  CO715_05440  ATI05221.1  246 aa YebC/PmpR family DNA-binding transcriptional regulator n.s. ○○○○○ 0.17 0.172223472984027
Escherichia coli M12  CO715_15970  ATI07076.1  483 aa Trk system potassium transporter TrkH n.s. ○○○○○ 0.17 0.173266703055271
Escherichia coli M12  CO715_07340  ATI05544.1  235 aa Ni/Fe-hydrogenase, b-type cytochrome subunit n.s. ○○○○○ 0.18 0.181403897610977
Escherichia coli M12  CO715_17060  ATI07274.1  78 aa hypothetical protein n.s. ○○○○○ 0.19 0.191418906294922
Escherichia coli M12  CO715_00100  ATI04275.1  770 aa penicillin-binding protein 1C n.s. ○○○○○ 0.2 0.196426410636895
Escherichia coli M12  CO715_21600  ATI08092.1  192 aa DedA family protein n.s. ○○○○○ 0.2 0.19726099469389
Escherichia coli M12  CO715_12660  ATI06481.1  154 aa toxin YhaV n.s. ○○○○○ 0.2 0.201225268964619
Escherichia coli M12  CO715_16530  ATI07180.1  380 aa crotonobetainyl-CoA dehydrogenase n.s. ○○○○○ 0.22 0.221881224375256
Escherichia coli M12  CO715_02445  ATI04693.1  287 aa YicC family protein n.s. ○○○○○ 0.22 0.223759038503496
Escherichia coli M12  CO715_15240  ATI06948.1  298 aa sulfolactaldehyde 3-reductase n.s. ○○○○○ 0.24 0.235234569287183
Escherichia coli M12  CO715_20360  ATI08874.1  193 aa acetyltransferase n.s. ○○○○○ 0.24 0.237738321458169
Retrieved entries 2,101–2,200 out of 3,550 total in 53.2 ms (Link to these results)