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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1480  NP_231121.1  Q9KS03  110 aa hypothetical protein 0.00047 ○○○○○ 0.6 0.602240920315725
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3831  AIK82381.1  87 aa hypothetical protein 0.00055 ○○○○○ 0.6 0.602637118038814
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5083  AIK83609.1  341 aa P-type DNA transfer ATPase VirB11 1.8e-5 ○○○○○ 0.6 0.604079380796873
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4495  AIK83033.1  188 aa fructose-1-phosphatase 4.3e-14 ○○○○○ 0.61 0.605084297064469
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0667  NP_233056.1  Q9KLS4  513 aa sodium/solute symporter 0.012 ○○○○○ 0.61 0.606222419360291
Porphyromonas gingivalis ATCC 33277  PGN_0081  WP_012457225.1  B2RGV5  452 aa MATE family efflux transporter <1e-323 ○○○○○ 0.61 0.606794014689753
Escherichia coli M12  CO715_24630  ATI08613.1  463 aa L-selenocysteinyl-tRNA(Sec) synthase 0.0089 ○○○○○ 0.61 0.606833120664405
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2621  NP_232249.1  Q9KNV9  869 aa extracellular nuclease-like protein 0.026 ○○○○○ 0.61 0.608446382514569
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4917  AIK83443.1  396 aa mannonate dehydratase <1e-323 ○○○○○ 0.61 0.609457494166738
Escherichia coli M12  CO715_16020  ATI07084.1  416 aa fimbrial protein 0.017 ○○○○○ 0.61 0.610171456892387
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4342  AIK82887.1  507 aa cobyric acid synthase CobQ <1e-323 ○○○○○ 0.61 0.610396761677224
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4881  AIK83408.1  966 aa response regulator <1e-323 ○○○○○ 0.61 0.610562532832961
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0274  NP_229930.1  Q9KV82  244 aa hypothetical protein 0.019 ○○○○○ 0.61 0.610934009598262
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0537  NP_230188.1  Q9KUI4  295 aa cysteine synthase B 0.033 ○○○○○ 0.61 0.610989410293417
Porphyromonas gingivalis ATCC 33277  PGN_0082  WP_012457226.1  B2RGV6  282 aa AraC family transcriptional regulator <1e-323 ○○○○○ 0.61 0.611219928853152
Porphyromonas gingivalis ATCC 33277  PGN_1119  WP_004585532.1  B2RJU3  mscL  139 aa large-conductance mechanosensitive channel protein MscL 1.7e-7 ○○○○○ 0.61 0.611691507950446
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2314  NP_231945.1  Q9KPQ2  134 aa hypothetical protein 0.0073 ○○○○○ 0.61 0.612120838258264
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4372  AIK82915.1  407 aa acyl-CoA dehydrogenase, N-terminal domain protein 0.00021 ○○○○○ 0.61 0.612174478400334
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1346  NP_230990.1  Q9KSB3  339 aa hypothetical protein 0.00076 ○○○○○ 0.61 0.613241418914659
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0312  NP_229966.1  Q9KV46  236 aa FMN reductase 4.8e-5 ○○○○○ 0.61 0.61375838294103
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2410  AIK81007.1  404 aa type II secretion system protein F 3.9e-11 ○○○○○ 0.61 0.614269604006463
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2567  AIK81164.1  476 aa amino acid carrier family protein <1e-323 ○○○○○ 0.62 0.61704974236054
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0280  NP_229936.1  Q9KV76  445 aa lysine/cadaverine antiporter 0.005 ○○○○○ 0.62 0.61743347502293
Porphyromonas gingivalis ATCC 33277  PGN_0144  WP_012457276.1  B2RH18  419 aa DUF5103 domain-containing protein 0.0095 ○○○○○ 0.62 0.61926819262606
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2255  AIK80860.1  231 aa branched-chain amino-acid ABC transport system ATP-binding protein 1.7e-8 ○○○○○ 0.62 0.619471852231759
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1367  NP_231011.1  Q9KS92  667 aa GGDEF family protein 0.0015 ○○○○○ 0.62 0.619803791004649
Escherichia coli M12  CO715_15290  ATI06957.1  72 aa hypothetical protein 0.018 ○○○○○ 0.62 0.620186465576332
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2399  AIK80996.1  265 aa fhuC 2.0e-7 ○○○○○ 0.62 0.620853972251209
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1744  AIK80364.1  1021 aa acrB/AcrD/AcrF family protein <1e-323 ○○○○○ 0.62 0.621136716756788
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1330  AIK79953.1  378 aa potA 2.4e-11 ○○○○○ 0.62 0.623288147544782
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4189  AIK82734.1  298 aa urea transporter <1e-323 ○○○○○ 0.62 0.623984853682367
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0344  NP_232740.1  Q9KMJ9  141 aa hypothetical protein 0.015 ○○○○○ 0.62 0.624337232331108
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4877  AIK83404.1  240 aa acetyl-CoA acetyltransferase 2.0e-7 ○○○○○ 0.63 0.627065674442661
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1580  NP_231220.1  Q9KRQ6  303 aa LysR family transcriptional regulator 0.0067 ○○○○○ 0.63 0.62745520648051
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4155  AIK82701.1  219 aa channel, hemolysin III family protein <1e-323 ○○○○○ 0.63 0.627562378415066
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4551  AIK83089.1  1050 aa RND transporter, hydrophobe/amphiphile efflux-1 family protein <1e-323 ○○○○○ 0.63 0.627684431672049
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1587  AIK80206.1  337 aa NAD dependent epimerase/dehydratase family protein 0.0012 ○○○○○ 0.63 0.627908447277355
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2553  NP_232181.1  Q9KP26  238 aa ABC transporter ATP-binding protein, authentic frameshift 8.3e-6 ○○○○○ 0.63 0.628224152293683
Escherichia coli M12  CO715_16445  ATI07163.1  243 aa UDP pyrophosphate phosphatase 0.015 ○○○○○ 0.63 0.628323660132038
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1987  AIK80593.1  217 aa oxygen-insensitive NAD(P)H nitroreductase 0.0073 ○○○○○ 0.63 0.629158835127398
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3013  AIK81598.1  343 aa ABC transporter family protein 6.4e-6 ○○○○○ 0.63 0.629300670166618
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1636  AIK80256.1  349 aa phage portal protein, PBSX family 2.3e-15 ○○○○○ 0.63 0.629631123297348
Escherichia coli M12  CO715_14510  ATI06815.1  452 aa PTS galactitol transporter subunit IIC 0.026 ○○○○○ 0.63 0.62978418223178
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2497  AIK81094.1  677 aa NADH:flavin oxidoreductase / NADH oxidase familyprotein <1e-323 ○○○○○ 0.63 0.629811590268257
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4537  AIK83075.1  183 aa fimbrial family protein 1.5e-10 ○○○○○ 0.63 0.630554228981787
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2609  AIK81203.1  45 aa hypothetical protein 0.0017 ○○○○○ 0.63 0.63136905647958
Escherichia coli M12  CO715_14450  ATI06803.1  499 aa Low-affinity inorganic phosphate transporter 1 0.0036 ○○○○○ 0.63 0.632079288388517
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2743  NP_232369.1  Q9KNJ5  184 aa hypothetical protein 0.0017 ○○○○○ 0.63 0.632282772980609
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0974  NP_230621.1  P0C6D2  cueR  139 aa MerR family transcriptional regulator 0.015 ○○○○○ 0.63 0.632283623869075
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4911  AIK83437.1  601 aa yejA <1e-323 ○○○○○ 0.63 0.632318291262897
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5175  AIK83696.1  108 aa phage gp6-like head-tail connector family protein 5.6e-10 ○○○○○ 0.63 0.63268285354911
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1006  AIK79629.1  332 aa glyceraldehyde-3-phosphate dehydrogenase, type I <1e-323 ○○○○○ 0.63 0.63335415895525
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5159  AIK83680.1  269 aa DNA adenine methylase family protein 0.04 ○○○○○ 0.63 0.633961246549959
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2089  AIK80694.1  40 aa hypothetical protein 0.0028 ○○○○○ 0.63 0.634006705543546
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1613  AIK80233.1  559 aa putative orf35 1.9e-7 ○○○○○ 0.63 0.634100835194895
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0647  NP_233036.1  Q9KLU4  148 aa hypothetical protein 0.048 ○○○○○ 0.63 0.634231739189318
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4789  AIK83316.1  436 aa acetyl-CoA C-acyltransferase FadI 1.6e-11 ○○○○○ 0.63 0.634283725516484
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5179  AIK83700.1  163 aa structural protein 3 1.5e-6 ○○○○○ 0.63 0.634913681921416
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1289  NP_230934.1  Q9KSG7  631 aa methyl-accepting chemotaxis protein 0.0015 ○○○○○ 0.63 0.634951229863983
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2003  NP_231637.2  Q9KQJ5  272 aa 23S rRNA (guanine(745)-N(1))-methyltransferase 0.0046 ○○○○○ 0.63 0.634975067445009
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2075  AIK80680.1  228 aa ABC transporter family protein 8.5e-5 ○○○○○ 0.64 0.635646475719442
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0648  NP_230297.1  Q9KU75  303 aa lipoprotein NlpI 0.0029 ○○○○○ 0.64 0.636708541623031
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2129  AIK80734.1  287 aa high-affinity nickel-transport family protein 1.4e-9 ○○○○○ 0.64 0.636767247012266
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2157  AIK80762.1  88 aa bolA transcriptional regulator BolA transcriptional dual regulator 3.0e-8 ○○○○○ 0.64 0.637231517776579
Escherichia coli M12  CO715_03590  ATI04902.1  400 aa acetate kinase 0.008 ○○○○○ 0.64 0.637921376787485
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4902  AIK83428.1  295 aa bacterial regulatory helix-turn-helix, lysR family protein 0.00088 ○○○○○ 0.64 0.638309946036308
Escherichia coli M12  CO715_23100  ATI08361.1  368 aa N-acetylneuraminate epimerase 0.00015 ○○○○○ 0.64 0.638338668815983
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1522  AIK80142.1  412 aa amidase, hydantoinase/carbamoylase family protein 0.0035 ○○○○○ 0.64 0.638850914912223
Escherichia coli M12  CO715_15345  ATI06967.1  419 aa L-rhamnose isomerase 0.012 ○○○○○ 0.64 0.638964606858729
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3197  AIK81765.1  332 aa thermophilic reversible gamma-resorcylate decarboxylase <1e-323 ○○○○○ 0.64 0.639547695528138
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2145  AIK80750.1  566 aa bacterial extracellular solute-binding, 5 Middlefamily protein <1e-323 ○○○○○ 0.64 0.639725642023855
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0399  NP_230053.1  Q9KUW0  479 aa MSHA biogenesis protein MshI 0.00022 ○○○○○ 0.64 0.640122085241495
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0027  NP_232428.1  Q9KND8  849 aa chitinase 0.019 ○○○○○ 0.64 0.640395051882013
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2750  NP_232376.1  Q9KNI8  849 aa GGDEF family protein 0.027 ○○○○○ 0.64 0.640397081267735
Escherichia coli M12  CO715_02570  ATI04715.1  565 aa transcriptional regulator HilA 0.016 ○○○○○ 0.64 0.640425128958471
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0701  NP_230350.1  Q9KU28  trpR  118 aa Trp operon repressor 0.01 ○○○○○ 0.64 0.641173150138728
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1710  NP_231346.1  Q9KRD2  818 aa hypothetical protein 0.014 ○○○○○ 0.64 0.641252837559725
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2226  AIK80830.1  236 aa hypothetical protein <1e-323 ○○○○○ 0.64 0.641564406057933
Porphyromonas gingivalis ATCC 33277  PGN_0242  WP_012457360.1  B2RHB6  382 aa glycosyltransferase family 1 protein 0.028 ○○○○○ 0.64 0.641719191842729
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0308  NP_229963.1  Q9KV49  330 aa hypothetical protein 0.026 ○○○○○ 0.64 0.642370887534014
Escherichia coli M12  CO715_12250  ATI06411.1  292 aa glucose-1-phosphate thymidylyltransferase RfbA 0.0096 ○○○○○ 0.64 0.642720235115209
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3030  AIK81615.1  397 aa tyrosine aminotransferase 4.4e-8 ○○○○○ 0.64 0.642743176021112
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3325  AIK81882.1  152 aa asnC transcriptional repressor AsnC transcriptional dual regulator 3.1e-8 ○○○○○ 0.64 0.642824866499539
Escherichia coli M12  CO715_08035  ATI05665.1  261 aa (S)-ureidoglycine aminohydrolase 0.003 ○○○○○ 0.64 0.642928881129458
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1980  NP_231614.1  Q9KQL8  200 aa hypothetical protein 0.011 ○○○○○ 0.64 0.643424133815915
Escherichia coli M12  CO715_15485  ATI08828.1  224 aa hypothetical protein 1.6e-6 ○○○○○ 0.64 0.643763465186453
Escherichia coli M12  CO715_12200  ATI06403.1  400 aa sugar transporter 0.05 ○○○○○ 0.64 0.644806695257698
Escherichia coli M12  CO715_18525  ATI08858.1  1524 aa outer membrane autotransporter barrel domain-containing protein 6.6e-5 ○○○○○ 0.65 0.645015341271946
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2095  AIK80700.1  201 aa recombination protein RecR 2.0e-5 ○○○○○ 0.65 0.645136808655631
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2367  NP_231997.1  Q9KPK0  127 aa hypothetical protein 0.047 ○○○○○ 0.65 0.645537033179864
Escherichia coli M12  CO715_14350  ATI06783.1  188 aa outer membrane protein slp 0.0036 ○○○○○ 0.65 0.645849925328942
Escherichia coli M12  CO715_15040  ATI06913.1  284 aa AraC family transcriptional regulator 0.046 ○○○○○ 0.65 0.645849925328942
Porphyromonas gingivalis ATCC 33277  PGN_1796  WP_012458537.1  B2RLS0  1125 aa TIR domain-containing protein 1.2e-7 ○○○○○ 0.65 0.646285905165217
Escherichia coli M12  CO715_02225  ATI04653.1  728 aa hypothetical protein 0.0034 ○○○○○ 0.65 0.646475863371688
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2497  NP_232126.1  Q9KP78  417 aa hypothetical protein 0.048 ○○○○○ 0.65 0.646544030746926
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0693  NP_230342.1  Q9KU36  237 aa two-component response-regulatory protein YehT 0.00098 ○○○○○ 0.65 0.64669258352063
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0678  NP_233066.1  Q9KLR4  napA  829 aa nitrate reductase catalytic subunit 0.0062 ○○○○○ 0.65 0.646767658823018
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1135  NP_230780.1  Q9KSX1  hisB  357 aa imidazole glycerol-phosphate dehydratase/histidinol phosphatase 0.042 ○○○○○ 0.65 0.647214216667073
Escherichia coli M12  CO715_02210  ATI04650.1  543 aa hypothetical protein 0.00016 ○○○○○ 0.65 0.647519093442933
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2935  AIK81521.1  478 aa aspartate ammonia-lyase <1e-323 ○○○○○ 0.65 0.647870505151694
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