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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2127  CBW18223.1  A0A0H3ND79  stcC  829 aa hypothetical outer membrane usher protein n.s. ●○○○○ -0.95 -0.954681385278798
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1382  WP_000751447.1  E8XH71  pykF  470 aa pyruvate kinase I n.s. ●○○○○ -0.95 -0.954377188186196
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0715  WP_001018621.1  E8XA46  fldA  176 aa flavodoxin FldA n.s. ●○○○○ -0.95 -0.95422363357387
Escherichia coli O157:H7 str. EDL933  Z0030  AAG54328.1  938 aa isoleucine tRNA synthetase n.s. ●○○○○ -0.95 -0.95421067915277
Vibrio parahaemolyticus RIMD 2210633  VPA_1226  BAC62569.1  Q87GT9  104 aa conserved hypothetical protein n.s. ●○○○○ -0.95 -0.954003418125114
Serratia marcescens Strain UMH9  BVG96_13330  ASL98547.1  314 aa transcriptional regulator LrhA n.s. ●○○○○ -0.95 -0.953890642250265
Streptococcus pyogenes M1 5448  SP5448_07970  WP_010921917.1  248 aa site-specific tyrosine recombinase XerD n.s. ●○○○○ -0.95 -0.953822364399307
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0009  CBW16110.1  A0A0H3NGX4  yaaH  188 aa conserved hypothetical protein n.s. ●○○○○ -0.95 -0.953635536107801
Escherichia coli CFT073  c1144  AAN79612.1  Q8FJ45  rutF  184 aa Putative flavin:NADH reductase ycdH n.s. ●○○○○ -0.95 -0.953588768769478
Serratia marcescens Strain UMH9  BVG96_20215  ASL99803.1  693 aa DNA helicase RecG n.s. ●○○○○ -0.95 -0.95299954148823
Serratia marcescens Strain UMH9  BVG96_19270  ASL99635.1  278 aa MurR/RpiR family transcriptional regulator n.s. ●○○○○ -0.95 -0.952872702390269
Escherichia coli CFT073  c3414  AAN81859.1  A0A0H2VA78  recB  1183 aa Exodeoxyribonuclease V beta chain n.s. ●○○○○ -0.95 -0.952589030386052
Serratia marcescens Strain UMH9  BVG96_03310  ASL96683.1  179 aa N-acetyltransferase n.s. ●○○○○ -0.95 -0.952379690761188
Haemophilus influenzae Rd KW20  HI_0393  NP_438555.1  P44681  ychF  363 aa GTP-dependent nucleic acid-binding protein EngD n.s. ●○○○○ -0.95 -0.951960873381254
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3522  CBW19616.1  A0A0H3NMP5  ugpA  295 aa glycerol-3-phosphate transport system permease protein n.s. ●○○○○ -0.95 -0.951756230992454
Escherichia coli O157:H7 str. EDL933  Z2414  AAG56451.1  79 aa unknown protein encoded within prophage CP-933R n.s. ●○○○○ -0.95 -0.951611615058164
Vibrio parahaemolyticus RIMD 2210633  VPA_1543  BAC62886.1  Q87FX7  fliQ  89 aa flagellar biosynthetic protein n.s. ●○○○○ -0.95 -0.951128817390695
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0035  CBW16136.1  A0A0H3N8T3  253 aa hypothetical exported protein n.s. ●○○○○ -0.95 -0.951119858454564
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4130  AIK82676.1  211 aa L-lysine exporter family protein n.s. ●○○○○ -0.95 -0.951038780925818
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0983  CBW17079.1  A0A0H3NF91  sodCa  177 aa bacteriophage encoded superoxide dismutase [cu-zn] 1 precursor (ec 1.15.1.1) (sodCI) n.s. ●○○○○ -0.95 -0.951029662249966
Vibrio parahaemolyticus RIMD 2210633  VPA_0982  BAC62325.1  Q79YT8  162 aa conserved hypothetical protein n.s. ●○○○○ -0.95 -0.951019137750188
Streptococcus pyogenes M1 5448  SP5448_08795  WP_002993568.1  101 aa streptopain n.s. ●○○○○ -0.95 -0.950938354905113
Mycobacterium avium subsp. paratuberculosis K10  MAP_1349c  AAS03666.1  Q740K1  219 aa hypothetical protein n.s. ●○○○○ -0.95 -0.950611917077588
Mycobacterium avium subsp. paratuberculosis K10  MAP_2334c  AAS04651.1  Q73XH5  240 aa hypothetical protein n.s. ●○○○○ -0.95 -0.950507576868566
Escherichia coli CFT073  c0709  AAN79182.1  A0A0H2V554  citC  335 aa [Citrate [pro-3S]-lyase] ligase n.s. ●○○○○ -0.95 -0.950396405483872
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3792  CBW19883.1  A0A0H3NHN0  torS  911 aa Two-component sensor protein histidine protein kinase. n.s. ●○○○○ -0.95 -0.95012250520013
Streptococcus pyogenes M1 5448  SP5448_09045  WP_010922748.1  243 aa peroxide stress protein YaaA n.s. ●○○○○ -0.95 -0.949977018407048
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2406  WP_000555674.1  E8XEF2  menF  431 aa isochorismate synthase MenF n.s. ●○○○○ -0.95 -0.949404924208835
Vibrio parahaemolyticus RIMD 2210633  VP_0730  BAC58993.1  Q87RP7  299 aa putative hemolysin n.s. ●○○○○ -0.95 -0.948798229016875
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2175  CBW18271.1  A0A0H3NDJ7  440 aa hypothetical regulatory protein n.s. ●○○○○ -0.95 -0.948667303198897
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4232  CBW20318.1  A0A0H3NIW6  adiY  253 aa hypothetical AraC family regulatory protein n.s. ●○○○○ -0.95 -0.948657033630692
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3509  CBW19603.1  A0A0H3NT79  gntR  331 aa gluconate utilization operon repressor n.s. ●○○○○ -0.95 -0.94847248116319
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1245  WP_002859297.1  A0A0H3PBJ3  541 aa potassium transporter n.s. ●○○○○ -0.95 -0.948279645908
Vibrio parahaemolyticus RIMD 2210633  VP_1440  BAC59703.1  Q87PR1  210 aa hypothetical protein n.s. ●○○○○ -0.95 -0.948057389348984
Streptococcus pyogenes M1 5448  SP5448_03230  WP_011285641.1  443 aa Sapep family Mn(2+)-dependent dipeptidase n.s. ●○○○○ -0.95 -0.948054345410918
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3801  CBW19892.1  A0A0H3NJC5  298 aa hypothetical LysR-family transcriptioanl regulator n.s. ●○○○○ -0.95 -0.947702111434001
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0799  WP_002856943.1  A0A0H3PHL6  246 aa AcfC family adhesin PEB2 n.s. ●○○○○ -0.95 -0.947583309552
Escherichia coli CFT073  c2953  AAN81403.1  Q8FFB5  pdxK  283 aa Pyridoxine kinase n.s. ●○○○○ -0.95 -0.947411029849396
Escherichia coli CFT073  c1044  AAN79514.1  A0A0H2V7V6  ycaP  230 aa Hypothetical protein ycaP n.s. ●○○○○ -0.95 -0.947411029849396
Escherichia coli CFT073  c2636  AAN81092.1  A0A0H2VB38  yehB  831 aa Hypothetical outer membrane usher protein yehB precursor n.s. ●○○○○ -0.95 -0.947343114759342
Serratia marcescens Strain UMH9  BVG96_08420  ASL97639.1  262 aa spermidine synthase n.s. ●○○○○ -0.95 -0.947135965005447
Escherichia coli CFT073  c2744  AAN81198.1  P0AAL4  napG  231 aa Ferredoxin-type protein napG n.s. ●○○○○ -0.95 -0.946932184932075
Escherichia coli O157:H7 str. EDL933  Z5848  AAG59435.1  712 aa anaerobic ribonucleoside-triphosphate reductase n.s. ●○○○○ -0.95 -0.946610845375859
Escherichia coli O157:H7 str. EDL933  Z3089  AAG57005.1  209 aa putative tail fiber component Z of prophage CP-933U n.s. ●○○○○ -0.95 -0.946610845375859
Serratia marcescens Strain UMH9  BVG96_14090  ASL98686.1  575 aa phosphoenolpyruvate--protein phosphotransferase n.s. ●○○○○ -0.95 -0.946454940966222
Escherichia coli CFT073  c0897  AAN79370.1  A0A0H2V5G2  63 aa Hypothetical protein n.s. ●○○○○ -0.95 -0.945949829524785
Vibrio parahaemolyticus RIMD 2210633  VPA_0011  BAC61354.1  Q87K87  238 aa conserved hypothetical protein n.s. ●○○○○ -0.95 -0.94591420268392
Mycobacterium avium subsp. paratuberculosis K10  MAP_3375  AAS05925.1  Q73UJ3  fbiB  449 aa hypothetical protein n.s. ●○○○○ -0.95 -0.945787106820453
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0930  WP_002865901.1  A1VZQ6  cheR  262 aa methyltransferase domain-containing protein n.s. ●○○○○ -0.95 -0.945718787394
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0780  CBW16878.1  A0A0H3NB06  moaC  161 aa molybdenum cofactor biosynthesis protein C n.s. ●○○○○ -0.95 -0.945259050460885
Escherichia coli M12  CO715_21260  ATI08032.1  185 aa thiol:disulfide interchange protein n.s. ●○○○○ -0.94 -0.944867287304376
Escherichia coli O157:H7 str. EDL933  Z3182  AAG57079.1  434 aa L-histidinal:NAD+ oxidoreductase; L-histidinol:NAD+ oxidoreductase n.s. ●○○○○ -0.94 -0.944683958271412
Escherichia coli CFT073  c0224  AAN78716.1  A0A0H2V490  ldcC  713 aa Lysine decarboxylase, constitutive n.s. ●○○○○ -0.94 -0.944613140522434
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2716  CBW18817.1  A0A0H3NEW4  188 aa bacteriophage polarity suppression protein n.s. ●○○○○ -0.94 -0.944544604466673
Haemophilus influenzae Rd KW20  HI_0011  NP_438184.1  P43750  holD  134 aa DNA polymerase III subunit psi n.s. ●○○○○ -0.94 -0.944468157943821
Serratia marcescens Strain UMH9  BVG96_15770  ASM00564.1  126 aa hypothetical protein n.s. ●○○○○ -0.94 -0.944441578676976
Mycobacterium avium subsp. paratuberculosis K10  MAP_0964c  AAS03281.1  Q741X3  513 aa hypothetical protein n.s. ●○○○○ -0.94 -0.943967388319634
Haemophilus influenzae Rd KW20  HI_0571  NP_438728.1  P44418  oxyR  301 aa DNA-binding transcriptional regulator OxyR n.s. ●○○○○ -0.94 -0.943812522081598
Vibrio parahaemolyticus RIMD 2210633  VPA_1054  BAC62397.1  Q87HB1  111 aa putative nitrite reductase NADPH (small subunit) oxidoreductase protein n.s. ●○○○○ -0.94 -0.943810124591107
Escherichia coli M12  CO715_06190  ATI05344.1  63 aa hypothetical protein n.s. ●○○○○ -0.94 -0.943615411218883
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3421  WP_000249229.1  E8XC81  yraM  680 aa penicillin-binding protein activator n.s. ●○○○○ -0.94 -0.943252975560375
Streptococcus pyogenes M1 5448  SP5448_01245  WP_010921879.1  276 aa MurR/RpiR family transcriptional regulator n.s. ●○○○○ -0.94 -0.943247662920594
Streptococcus pyogenes M1 5448  SP5448_01215  WP_010921874.1  439 aa carbohydrate ABC transporter substrate-binding protein n.s. ●○○○○ -0.94 -0.943247662920594
Escherichia coli CFT073  c1332  AAN79805.1  P69368  mdtH  412 aa Hypothetical transport protein yceL n.s. ●○○○○ -0.94 -0.942990646608343
Escherichia coli CFT073  c1321  AAN79794.1  Q8FIR7  yceA  368 aa Hypothetical protein yceA n.s. ●○○○○ -0.94 -0.942947625723737
Mycobacterium avium subsp. paratuberculosis K10  MAP_2277c  AAS04594.1  Q73XN2  656 aa hypothetical protein n.s. ●○○○○ -0.94 -0.942120289360527
Mycobacterium avium subsp. paratuberculosis K10  MAP_3099c  AAS05647.1  Q73VB5  246 aa hypothetical protein n.s. ●○○○○ -0.94 -0.941897930327433
Escherichia coli CFT073  c2889  AAN81339.1  Q8CVU7  fadL  448 aa Long-chain fatty acid transport protein precursor n.s. ●○○○○ -0.94 -0.941801856783533
Escherichia coli CFT073  c4707  AAN83140.1  A0A0H2VCK2  wecC  420 aa UDP-N-acetyl-D-mannosamine dehydrogenase n.s. ●○○○○ -0.94 -0.941725876869292
Escherichia coli CFT073  c0703  AAN79178.1  A0A0H2V548  464 aa Hypothetical protein n.s. ●○○○○ -0.94 -0.941493172489859
Escherichia coli CFT073  c0704  AAN79179.1  A0A0H2V567  citF  510 aa Citrate lyase alpha chain n.s. ●○○○○ -0.94 -0.941493172489859
Streptococcus pyogenes M1 5448  SP5448_03285  WP_002983840.1  67 aa DUF910 family protein n.s. ●○○○○ -0.94 -0.941324989924465
Mycobacterium avium subsp. paratuberculosis K10  MAP_1108  AAS03425.1  Q741I2  301 aa hypothetical protein n.s. ●○○○○ -0.94 -0.940896306371737
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4454  CBW20543.1  A0A0H3NL86  symE  110 aa endoribonuclease n.s. ●○○○○ -0.94 -0.940695700730578
Streptococcus pyogenes M1 5448  SP5448_08440  WP_010922671.1  193 aa serine O-acetyltransferase n.s. ●○○○○ -0.94 -0.9403636534264
Mycobacterium avium subsp. paratuberculosis K10  MAP_3342  AAS05892.1  Q73UM4  274 aa hypothetical protein n.s. ●○○○○ -0.94 -0.940025340173889
Vibrio parahaemolyticus RIMD 2210633  VP_0803  BAC59066.1  Q87RJ1  47 aa hypothetical protein n.s. ●○○○○ -0.94 -0.939919651638687
Escherichia coli CFT073  c1815  AAN80279.1  A0A0H2V766  ydaM  430 aa Hypothetical protein ydaM n.s. ●○○○○ -0.94 -0.939825548324505
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0922  WP_002853544.1  A0A0H3PA30  137 aa acyl-CoA thioesterase n.s. ●○○○○ -0.94 -0.939502418122
Streptococcus pyogenes M1 5448  SP5448_06260  WP_010922156.1  307 aa 2-dehydropantoate 2-reductase n.s. ●○○○○ -0.94 -0.939402316928335
Mycobacterium avium subsp. paratuberculosis K10  MAP_2324c  AAS04641.1  Q73XI5  784 aa hypothetical protein n.s. ●○○○○ -0.94 -0.939227934746755
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1001  WP_002869157.1  A0A0H3P9B9  cjaA  279 aa transporter substrate-binding domain-containing protein n.s. ●○○○○ -0.94 -0.938938760027
Vibrio parahaemolyticus RIMD 2210633  VP_2062  BAC60325.1  Q87N14  rne  1023 aa ribonuclease E n.s. ●○○○○ -0.94 -0.938910510146789
Mycobacterium avium subsp. paratuberculosis K10  MAP_2152c  AAS04469.1  Q73Y06  124 aa hypothetical protein n.s. ●○○○○ -0.94 -0.938626100652869
Streptococcus pyogenes M1 5448  SP5448_03655  WP_011285618.1  153 aa DUF4355 domain-containing protein n.s. ●○○○○ -0.94 -0.93844098043027
Haemophilus influenzae Rd KW20  HI_0315  NP_438481.1  P44634  246 aa hypothetical protein n.s. ●○○○○ -0.94 -0.938188647202234
Mycobacterium avium subsp. paratuberculosis K10  MAP_4153  AAS06703.1  Q73SC1  pqqE  404 aa PqqE n.s. ●○○○○ -0.94 -0.938006015234522
Escherichia coli CFT073  c0850  AAN79323.1  A0A0H2V7H0  ybhB  158 aa Protein ybhB n.s. ●○○○○ -0.94 -0.936683148867249
Serratia marcescens Strain UMH9  BVG96_13730  ASL98624.1  245 aa heme ABC transporter permease n.s. ●○○○○ -0.94 -0.935856444564754
Vibrio parahaemolyticus RIMD 2210633  VP_2834  BAC61097.1  Q87KZ0  368 aa NlpD-related protein n.s. ●○○○○ -0.94 -0.935528750321601
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1189  CBW17284.1  A0A0H3NKE6  176 aa hypothetical cytochrome n.s. ●○○○○ -0.94 -0.93542713274645
Mycobacterium avium subsp. paratuberculosis K10  MAP_4325c  AAS06875.1  Q73RV3  306 aa hypothetical protein n.s. ●○○○○ -0.93 -0.934894837578217
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0547  CBW16646.1  A0A0H3NIN2  550 aa hypothetical membrane protein n.s. ●○○○○ -0.93 -0.934675590744724
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1444  CBW17539.1  A0A0H3NBB8  ydeJ  175 aa conserved hypothetical protein n.s. ●○○○○ -0.93 -0.934270061216538
Mycobacterium avium subsp. paratuberculosis K10  MAP_2357  AAS04674.1  Q73XF2  402 aa hypothetical protein n.s. ●○○○○ -0.93 -0.9341553955584
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4306  WP_001068659.1  E8XL78  argB  257 aa acetylglutamate kinase n.s. ●○○○○ -0.93 -0.933963486788713
Vibrio parahaemolyticus RIMD 2210633  VPA_1370  BAC62714.1  Q87GE5  484 aa hypothetical protein n.s. ●○○○○ -0.93 -0.933930276371497
Haemophilus influenzae Rd KW20  HI_0765  NP_438924.2  Q57125  278 aa lipooligosaccharide biosynthesis protein n.s. ●○○○○ -0.93 -0.93385253215902
Streptococcus pyogenes M1 5448  SP5448_03720  WP_011285614.1  145 aa DUF1617 family protein n.s. ●○○○○ -0.93 -0.933634297939946
Streptococcus pyogenes M1 5448  SP5448_07145  WP_002985576.1  51 aa hypothetical protein n.s. ●○○○○ -0.93 -0.933634297939946
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