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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0757  WP_002867836.1  A0A0H3P9J8  cjaC  251 aa basic amino acid ABC transporter substrate-binding protein n.s. ●○○○○ -0.89 -0.893933730081
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0122  WP_002854440.1  A0A0H3PGM1  aspA  468 aa aspartate ammonia-lyase n.s. ●○○○○ -0.89 -0.893736982887
Serratia marcescens Strain UMH9  BVG96_13290  ASL98541.1  180 aa NADH-quinone oxidoreductase subunit I n.s. ●○○○○ -0.89 -0.893327664683218
Streptococcus pyogenes M1 5448  SP5448_02495  WP_002983488.1  100 aa YlxQ-related RNA-binding protein n.s. ●○○○○ -0.89 -0.893258165021225
Streptococcus pyogenes M1 5448  SP5448_06245  WP_010922158.1  648 aa PTS fructose transporter subunit IIC n.s. ●○○○○ -0.89 -0.893258165021225
Escherichia coli CFT073  c3551  AAN81999.1  P0C067  mltC  360 aa Membrane-bound lytic murein transglycosylase C precursor n.s. ●○○○○ -0.89 -0.893180474021766
Vibrio parahaemolyticus RIMD 2210633  VP_0934  BAC59197.1  Q87R64  42 aa hypothetical protein n.s. ●○○○○ -0.89 -0.893161646331287
Vibrio parahaemolyticus RIMD 2210633  VP_0692  BAC58955.1  Q87RT5  306 aa transcriptional regulator, LysR family n.s. ●○○○○ -0.89 -0.892436335789556
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3528  CBW19622.1  A0A0H3NH39  livM  425 aa high-affinity branched-chain amino acid transport system permease protein n.s. ●○○○○ -0.89 -0.89241836031125
Streptococcus pyogenes M1 5448  SP5448_01970  WP_076639994.1  168 aa universal stress protein n.s. ●○○○○ -0.89 -0.89229682852316
Escherichia coli O157:H7 str. EDL933  Z3041  AAG56966.1  207 aa positive regulator for ctr capsule biosynthesis, positive transcription factor n.s. ●○○○○ -0.89 -0.891948300016346
Serratia marcescens Strain UMH9  BVG96_00600  ASL96198.1  223 aa 7-carboxy-7-deazaguanine synthase QueE n.s. ●○○○○ -0.89 -0.891767437965636
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1302  WP_002854065.1  A1W0R9  mqnA  223 aa chorismate dehydratase n.s. ●○○○○ -0.89 -0.891189251265
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0902  WP_002869168.1  A0A0H3P9L9  rpsA  556 aa 30S ribosomal protein S1 n.s. ●○○○○ -0.89 -0.891173675508
Escherichia coli CFT073  c0783  AAN79256.1  Q8FJV3  kdpA  557 aa Potassium-transporting ATPase A chain n.s. ●○○○○ -0.89 -0.891015958558738
Vibrio parahaemolyticus RIMD 2210633  VP_0249  BAC58512.1  Q87T21  hslU  443 aa protease HslVU, ATPase subunit HslU n.s. ●○○○○ -0.89 -0.890853637882428
Vibrio parahaemolyticus RIMD 2210633  VP_2687  BAC60950.1  Q87LC5  489 aa cytoplasmic axial filament protein n.s. ●○○○○ -0.89 -0.89067652268766
Escherichia coli CFT073  c4706  AAN83139.1  A0A0H2VF94  wecB  390 aa UDP-N-acetylglucosamine 2-epimerase n.s. ●○○○○ -0.89 -0.890560964782645
Streptococcus pyogenes M1 5448  SP5448_04885  WP_010922353.1  306 aa type I pantothenate kinase n.s. ●○○○○ -0.89 -0.89037415552703
Streptococcus pyogenes M1 5448  SP5448_00280  WP_002986679.1  332 aa Holliday junction branch migration DNA helicase RuvB n.s. ●○○○○ -0.89 -0.89037415552703
Serratia marcescens Strain UMH9  BVG96_22145  ASM00146.1  598 aa fumarate reductase flavoprotein subunit n.s. ●○○○○ -0.89 -0.890207481658241
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3898  CBW19988.1  A0A0H3NNF8  cyaY  106 aa CyaY protein n.s. ●○○○○ -0.89 -0.889914791267819
Escherichia coli CFT073  c2960  AAN81410.1  A0A0H2VBR1  ucpA  315 aa Oxidoreductase ucpA n.s. ●○○○○ -0.89 -0.889847647323237
Mycobacterium avium subsp. paratuberculosis K10  MAP_3670  AAS06220.1  Q73TP8  329 aa hypothetical protein n.s. ●○○○○ -0.89 -0.889677866607119
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0834  CBW16931.1  A0A0H3NEQ7  561 aa hypothetical flavoprotein n.s. ●○○○○ -0.89 -0.889662722948102
Vibrio parahaemolyticus RIMD 2210633  VP_1529  BAC59792.1  Q87PH3  potA  377 aa spermidine/putrescine ABC transporter, ATP-binding protein n.s. ●○○○○ -0.89 -0.888473160615495
Streptococcus pyogenes M1 5448  SP5448_07740  WP_002993880.1  106 aa hypothetical protein n.s. ●○○○○ -0.89 -0.8884514825309
Escherichia coli O157:H7 str. EDL933  Z4705  AAG58454.1  270 aa FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) n.s. ●○○○○ -0.89 -0.887724995657975
Escherichia coli O157:H7 str. EDL933  Z2323  AAG56375.1  906 aa hypothetical protein n.s. ●○○○○ -0.89 -0.887724995657975
Serratia marcescens Strain UMH9  BVG96_07540  ASL97474.1  115 aa monothiol glutaredoxin, Grx4 family n.s. ●○○○○ -0.89 -0.887704202095087
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1449  AIK80070.1  75 aa yccJ-like family protein n.s. ●○○○○ -0.89 -0.88755273558908
Streptococcus pyogenes M1 5448  SP5448_08435  WP_010922670.1  76 aa hypothetical protein n.s. ●○○○○ -0.89 -0.887490146032836
Streptococcus pyogenes M1 5448  SP5448_08435  WP_011285183.1  90 aa hypothetical protein n.s. ●○○○○ -0.89 -0.887490146032836
Streptococcus pyogenes M1 5448  SP5448_04500  WP_011285571.1  126 aa hypothetical protein n.s. ●○○○○ -0.89 -0.887490146032836
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1413  WP_002869136.1  A0A0H3PDS0  kpsC  689 aa capsular polysaccharide biosynthesis protein n.s. ●○○○○ -0.89 -0.887082697959
Serratia marcescens Strain UMH9  BVG96_13470  ASL98574.1  166 aa colicin V production protein n.s. ●○○○○ -0.89 -0.88698059488449
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3712  CBW19806.1  A0A0H3NTU2  gltS  401 aa glutamate permease n.s. ●○○○○ -0.89 -0.886791437279749
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4175  CBW20262.1  A0A0H3NP83  dinF  441 aa hypothetical DNA-damage-inducible membrane protein n.s. ●○○○○ -0.89 -0.886658582222348
Streptococcus pyogenes M1 5448  SP5448_00630  WP_010921800.1  144 aa competence protein ComG n.s. ●○○○○ -0.89 -0.886528809534771
Serratia marcescens Strain UMH9  BVG96_10860  ASL98090.1  240 aa nitrate reductase molybdenum cofactor assembly chaperone n.s. ●○○○○ -0.89 -0.886282688399356
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3704  CBW19798.1  A0A0H3NHF7  205 aa hypothetical membrane protein n.s. ●○○○○ -0.89 -0.88595082029256
Vibrio parahaemolyticus RIMD 2210633  VPA_0931  BAC62274.1  Q87HN2  251 aa molybdenum ABC transporter, periplasmic molybdenum-binding protein n.s. ●○○○○ -0.89 -0.88580320509807
Escherichia coli CFT073  c3281  AAN81730.1  A0A0H2V9W9  hycE  569 aa Formate hydrogenlyase subunit 5 precursor n.s. ●○○○○ -0.89 -0.885599865711869
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2818  CBW18916.1  A0A0H3NGW2  gutQ  321 aa hypothetical phosphosugar binding protein n.s. ●○○○○ -0.89 -0.885425489086671
Mycobacterium avium subsp. paratuberculosis K10  MAP_0149c  AAS02466.1  Q745F0  334 aa hypothetical protein n.s. ●○○○○ -0.89 -0.885243959176655
Escherichia coli O157:H7 str. EDL933  Z0689  AAG54889.1  869 aa putative outer membrane protein, export function n.s. ●○○○○ -0.89 -0.885013414329763
Mycobacterium avium subsp. paratuberculosis K10  MAP_1873c  AAS04190.1  Q73YT2  575 aa hypothetical protein n.s. ●○○○○ -0.88 -0.884921163265875
Mycobacterium avium subsp. paratuberculosis K10  MAP_1761c  AAS04078.1  Q73Z42  417 aa hypothetical protein n.s. ●○○○○ -0.88 -0.88431966769937
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0995  WP_010790601.1  A1VZW5  cmoB  296 aa tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB n.s. ●○○○○ -0.88 -0.884318167706
Escherichia coli CFT073  c3880  AAN82321.1  P0ABQ3  garR  299 aa 2-hydroxy-3-oxopropionate reductase n.s. ●○○○○ -0.88 -0.883978014469369
Escherichia coli CFT073  c0393  AAN78874.1  A0A0H2V4L3  1376 aa Haemoglobin protease n.s. ●○○○○ -0.88 -0.883978014469369
Serratia marcescens Strain UMH9  BVG96_10345  ASL97995.1  233 aa tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB n.s. ●○○○○ -0.88 -0.883293117497286
Escherichia coli O157:H7 str. EDL933  Z0708  AAG54903.1  482 aa putative 2-component sensor protein n.s. ●○○○○ -0.88 -0.883229012675869
Serratia marcescens Strain UMH9  BVG96_21375  ASM00011.1  206 aa threonine export protein RhtC n.s. ●○○○○ -0.88 -0.883082471336325
Mycobacterium avium subsp. paratuberculosis K10  MAP_0592  AAS02909.1  Q743J3  phoR  478 aa PhoR n.s. ●○○○○ -0.88 -0.883074131806146
Mycobacterium avium subsp. paratuberculosis K10  MAP_2593c  AAS04910.1  Q73WR7  rocA  546 aa RocA n.s. ●○○○○ -0.88 -0.882988219179897
Escherichia coli CFT073  c0378  AAN78859.1  A0A0H2V4L1  mbhA  262 aa MbhA protein n.s. ●○○○○ -0.88 -0.882897888892738
Streptococcus pyogenes M1 5448  SP5448_06130  WP_010922171.1  391 aa hydroxymethylglutaryl-CoA synthase n.s. ●○○○○ -0.88 -0.882683463542512
Mycobacterium avium subsp. paratuberculosis K10  MAP_1283  AAS03600.1  Q740Q9  bioB  344 aa BioB n.s. ●○○○○ -0.88 -0.882568997038351
Haemophilus influenzae Rd KW20  HI_0166  NP_438335.1  O05011  nqrB  411 aa Na(+)-translocating NADH-quinone reductase subunit B n.s. ●○○○○ -0.88 -0.882515512600312
Serratia marcescens Strain UMH9  BVG96_03345  ASL96690.1  238 aa ABC transporter n.s. ●○○○○ -0.88 -0.882498301633853
Escherichia coli CFT073  c0245  AAN78735.1  A0A0H2V4V8  yafC  304 aa Hypothetical transcriptional regulator yafC n.s. ●○○○○ -0.88 -0.882307937119753
Mycobacterium avium subsp. paratuberculosis K10  MAP_1550c  AAS03867.1  Q73ZQ1  346 aa hypothetical protein n.s. ●○○○○ -0.88 -0.882272014079351
Streptococcus pyogenes M1 5448  SP5448_04575  WP_009880253.1  152 aa hypothetical protein n.s. ●○○○○ -0.88 -0.881722127044447
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2923  CBW19022.1  A0A0H3NR58  ygcB  887 aa conserved hypothetical protein n.s. ●○○○○ -0.88 -0.881406850734205
Escherichia coli O157:H7 str. EDL933  Z1968  AAG56056.1  485 aa trehalase, periplasmic n.s. ●○○○○ -0.88 -0.881361437946995
Mycobacterium avium subsp. paratuberculosis K10  MAP_2772c  AAS05089.1  Q73W88  404 aa hypothetical protein n.s. ●○○○○ -0.88 -0.880993788906352
Serratia marcescens Strain UMH9  BVG96_07365  ASL97443.1  345 aa hemin-degrading factor n.s. ●○○○○ -0.88 -0.880532080302217
Haemophilus influenzae Rd KW20  HI_0713  NP_438871.1  P44837  tig  432 aa trigger factor n.s. ●○○○○ -0.88 -0.880239562895268
Mycobacterium avium subsp. paratuberculosis K10  MAP_3331  AAS05881.1  Q73UN5  207 aa hypothetical protein n.s. ●○○○○ -0.88 -0.880152748412205
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2107  CBW18203.1  A0A0H3ND62  baeS  467 aa hypothetical two-component system sensor kinase n.s. ●○○○○ -0.88 -0.879949660184063
Serratia marcescens Strain UMH9  BVG96_15850  ASL99007.1  118 aa potassium:proton antiporter n.s. ●○○○○ -0.88 -0.879110391326528
Mycobacterium avium subsp. paratuberculosis K10  MAP_2534c  AAS04851.1  Q73WX6  671 aa hypothetical protein n.s. ●○○○○ -0.88 -0.879004721142221
Escherichia coli CFT073  c2007  AAN80467.1  A0A0H2V7K4  uidC  421 aa Membrane-associated protein uidC precursor n.s. ●○○○○ -0.88 -0.878982765284229
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0145  CBW16248.1  A0A0H3N7L9  nadC  248 aa nicotinate-nucleotide pyrophosphorylase n.s. ●○○○○ -0.88 -0.878848731810553
Streptococcus pyogenes M1 5448  SP5448_05125  WP_010922321.1  116 aa biotin/lipoyl-binding protein n.s. ●○○○○ -0.88 -0.878838117550252
Escherichia coli O157:H7 str. EDL933  Z3497  AAG57370.1  358 aa glycerophosphodiester phosphodiesterase, periplasmic n.s. ●○○○○ -0.88 -0.87836375357825
Escherichia coli O157:H7 str. EDL933  Z0859  AAG55031.1  472 aa deoxyribodipyrimidine photolyase (photoreactivation) n.s. ●○○○○ -0.88 -0.87836266052702
Vibrio parahaemolyticus RIMD 2210633  VPA_0738  BAC62081.1  Q87I68  198 aa putative fimbrial protein Z, transcriptional regulator (LuxR/UhpA family) n.s. ●○○○○ -0.88 -0.878359638815177
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1723  CBW17818.1  A0A0H3NC31  441 aa hypothetical glutamate dehydrogenase n.s. ●○○○○ -0.88 -0.878329783256457
Vibrio parahaemolyticus RIMD 2210633  VPA_0632  BAC61975.1  Q87IH4  174 aa hypothetical protein n.s. ●○○○○ -0.88 -0.878138722697003
Vibrio parahaemolyticus RIMD 2210633  VPA_0892  BAC62235.1  Q87HR4  61 aa hypothetical protein n.s. ●○○○○ -0.88 -0.877893213682145
Serratia marcescens Strain UMH9  BVG96_03180  ASL96658.1  458 aa ATP-dependent RNA helicase RhlE n.s. ●○○○○ -0.88 -0.877636412817659
Serratia marcescens Strain UMH9  BVG96_04360  ASL96880.1  78 aa antitoxin n.s. ●○○○○ -0.88 -0.877569508699886
Vibrio parahaemolyticus RIMD 2210633  VPA_1234  BAC62577.1  Q87GT1  151 aa putative transcriptional regulator n.s. ●○○○○ -0.88 -0.877532081746362
Escherichia coli CFT073  c2186  AAN80645.1  A0A0H2V7V4  yeaE  299 aa Hypothetical protein yeaE n.s. ●○○○○ -0.88 -0.877208438027807
Serratia marcescens Strain UMH9  BVG96_22750  ASM00253.1  471 aa PTS trehalose transporter subunit IIBC n.s. ●○○○○ -0.88 -0.876649686819268
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0052  WP_002868980.1  A0A0H3P9A9  461 aa cation:dicarboxylase symporter family transporter n.s. ●○○○○ -0.88 -0.876640842859
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2093  CBW18189.1  A0A0H3NIQ9  wzc  719 aa tyrosine-protein kinase n.s. ●○○○○ -0.88 -0.87656981439404
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4131  CBW20219.1  A0A0H3NV98  242 aa hypothetical protein n.s. ●○○○○ -0.88 -0.876536191694301
Mycobacterium avium subsp. paratuberculosis K10  MAP_0218  AAS02535.1  Q745L1  336 aa hypothetical protein n.s. ●○○○○ -0.88 -0.876416211207757
Vibrio parahaemolyticus RIMD 2210633  VPA_0519  BAC61862.1  Q87IT7  295 aa transcriptional regulator, LysR family n.s. ●○○○○ -0.88 -0.876321046368003
Escherichia coli CFT073  c2556  AAN81011.1  A0A0H2V8P4  gnd  468 aa 6-phosphogluconate dehydrogenase, decarboxylating n.s. ●○○○○ -0.88 -0.876101620459947
Mycobacterium avium subsp. paratuberculosis K10  MAP_2680c  AAS04997.1  Q73WI0  vapC  123 aa hypothetical protein n.s. ●○○○○ -0.88 -0.876058207226772
Vibrio parahaemolyticus RIMD 2210633  VP_0569  BAC58832.1  Q87S55  229 aa DNA-binding response regulator PhoB n.s. ●○○○○ -0.88 -0.875808896766175
Vibrio parahaemolyticus RIMD 2210633  VP_2387  BAC60650.1  Q87M71  263 aa transcriptional regulator, DeoR family n.s. ●○○○○ -0.88 -0.87564573338229
Escherichia coli CFT073  c1864  AAN80327.1  A0A0H2V8G7  ydcS  381 aa Putative ABC transporter Periplasmic binding protein ydcS precursor n.s. ●○○○○ -0.87 -0.874975326602151
Mycobacterium avium subsp. paratuberculosis K10  MAP_4047  AAS06597.1  Q73SM6  209 aa hypothetical protein n.s. ●○○○○ -0.87 -0.874969782929318
Mycobacterium avium subsp. paratuberculosis K10  MAP_2093c  AAS04410.1  Q73Y64  rocE  483 aa RocE n.s. ●○○○○ -0.87 -0.874911815123869
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2752  CBW18851.1  A0A0H3NKX9  660 aa hypothetical DNA/RNA helicase n.s. ●○○○○ -0.87 -0.874677419318375
Retrieved entries 10,301–10,400 out of 36,363 total in 141.3 ms (Link to these results)