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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2402  AIK80999.1  851 aa penicillin-binding protein 1B n.s. ●○○○○ -0.87 -0.874563329547033
Serratia marcescens Strain UMH9  BVG96_17555  ASL99316.1  148 aa hypothetical protein n.s. ●○○○○ -0.87 -0.873924621474602
Escherichia coli CFT073  c3576  AAN82024.1  A0A0H2VC16  100 aa Unknown in IS n.s. ●○○○○ -0.87 -0.873829037671226
Escherichia coli CFT073  c4816  AAN83245.1  A0A0H2VEE4  hemN  459 aa Oxygen-independent coproporphyrinogen III oxidase n.s. ●○○○○ -0.87 -0.873829037671226
Escherichia coli CFT073  c2887  AAN81337.1  Q8FFG3  fadI  436 aa Probable 3-ketoacyl-CoA thiolase n.s. ●○○○○ -0.87 -0.873529910128909
Escherichia coli CFT073  c2989  AAN81439.1  P0A868  talA  316 aa Transaldolase A n.s. ●○○○○ -0.87 -0.873529910128909
Escherichia coli CFT073  c1676  AAN80143.1  A0A0H2V971  chaA  395 aa Calcium/proton antiporter n.s. ●○○○○ -0.87 -0.873481172115416
Escherichia coli CFT073  c1339  AAN79810.1  A0A0H2V6A8  flgN  138 aa Flagella synthesis protein flgN n.s. ●○○○○ -0.87 -0.873313017899858
Escherichia coli CFT073  c0358  AAN78839.1  A0A0H2V6G9  159 aa Hypothetical protein n.s. ●○○○○ -0.87 -0.873213901276132
Escherichia coli CFT073  c0359  AAN78840.1  A0A0H2V4H8  40 aa Hypothetical protein n.s. ●○○○○ -0.87 -0.873213901276132
Streptococcus pyogenes M1 5448  SP5448_03545  WP_011285627.1  129 aa DnaD domain protein n.s. ●○○○○ -0.87 -0.873070098561864
Escherichia coli CFT073  c2664  AAN81120.1  A0A0H2V912  dld  582 aa D-lactate dehydrogenase n.s. ●○○○○ -0.87 -0.872662216288764
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1000  WP_002855823.1  A0A0H3PGZ4  cjaB  415 aa MFS transporter n.s. ●○○○○ -0.87 -0.872579156344
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1386  CBW17482.1  A0A0H3NCV0  rnfE  230 aa Electron transport complex protein rnfE n.s. ●○○○○ -0.87 -0.872455619405641
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2338  CBW18440.1  A0A0H3NDZ4  usg  337 aa hypothetical semialdehyde dehydrogenase n.s. ●○○○○ -0.87 -0.872073811061736
Escherichia coli O157:H7 str. EDL933  Z5954  AAG59537.1  180 aa hypothetical protein n.s. ●○○○○ -0.87 -0.87193969693563
Escherichia coli O157:H7 str. EDL933  Z0407  AAG54662.1  201 aa putative transcription factor n.s. ●○○○○ -0.87 -0.871579796394826
Vibrio parahaemolyticus RIMD 2210633  VPA_0590  BAC61933.1  Q87IL6  430 aa putative ATP-dependent RNA helicase n.s. ●○○○○ -0.87 -0.871529089941746
Vibrio parahaemolyticus RIMD 2210633  VPA_0259  BAC61602.1  Q87JJ0  29 aa hypothetical protein n.s. ●○○○○ -0.87 -0.871088724573256
Escherichia coli CFT073  c5438  AAN83858.1  Q8FA73  mdoB  763 aa Phosphoglycerol transferase I n.s. ●○○○○ -0.87 -0.871028871800536
Mycobacterium avium subsp. paratuberculosis K10  MAP_1151c  AAS03468.1  Q741E0  98 aa hypothetical protein n.s. ●○○○○ -0.87 -0.870873600700077
Escherichia coli M12  CO715_13720  ATI06670.1  128 aa reactive intermediate/imine deaminase n.s. ●○○○○ -0.87 -0.870589306231782
Mycobacterium avium subsp. paratuberculosis K10  MAP_3436c  AAS05986.1  Q73UD2  231 aa hypothetical protein n.s. ●○○○○ -0.87 -0.870216307164594
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1333  WP_002784894.1  Q939J7  pseA  378 aa N-acetyl sugar amidotransferase n.s. ●○○○○ -0.87 -0.869820031029
Mycobacterium avium subsp. paratuberculosis K10  MAP_1270c  AAS03587.1  Q740S2  glgX  732 aa GlgX_1 n.s. ●○○○○ -0.87 -0.86926300408082
Streptococcus pyogenes M1 5448  SP5448_08390  WP_002982710.1  148 aa 50S ribosomal protein L13 n.s. ●○○○○ -0.87 -0.869224752569604
Mycobacterium avium subsp. paratuberculosis K10  MAP_2584  AAS04901.1  Q73WS6  398 aa hypothetical protein n.s. ●○○○○ -0.87 -0.869159456940458
Vibrio parahaemolyticus RIMD 2210633  VPA_1508  BAC62851.1  Q87G10  29 aa hypothetical protein n.s. ●○○○○ -0.87 -0.869140286339932
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2262  CBW18364.1  A0A0H3NJK8  398 aa conserved hypothetical protein n.s. ●○○○○ -0.87 -0.868663765000687
Mycobacterium avium subsp. paratuberculosis K10  MAP_1719c  AAS04036.1  Q73Z84  204 aa hypothetical protein n.s. ●○○○○ -0.87 -0.868376676039986
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3634  CBW19727.1  A0A0H3NHA8  yiaL  154 aa conserved hypothetical protein n.s. ●○○○○ -0.87 -0.867962404251258
Mycobacterium avium subsp. paratuberculosis K10  MAP_4150c  AAS06700.1  Q73SC4  347 aa hypothetical protein n.s. ●○○○○ -0.87 -0.867830039225464
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3302  CBW19398.1  A0A0H3NGG8  gltB  1486 aa glutamate synthase [NADPH] large chain precursor n.s. ●○○○○ -0.87 -0.867711561735716
Escherichia coli CFT073  c0716  AAN79189.1  A0A0H2V552  ybeM  264 aa Putative amidase n.s. ●○○○○ -0.87 -0.867378988092214
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3188  AIK81756.1  420 aa nucleotide sugar dehydrogenase family protein n.s. ●○○○○ -0.87 -0.866761632177617
Escherichia coli O157:H7 str. EDL933  Z4332  AAG58116.1  433 aa putative cytotoxin n.s. ●○○○○ -0.87 -0.866535180285503
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1332  WP_011812786.1  A1W0U9  hisH1  201 aa imidazole glycerol phosphate synthase subunit HisH n.s. ●○○○○ -0.87 -0.866252365116
Streptococcus pyogenes M1 5448  SP5448_02910  WP_002991882.1  125 aa S1 RNA-binding domain-containing protein n.s. ●○○○○ -0.87 -0.865379406577345
Mycobacterium avium subsp. paratuberculosis K10  MAP_2284c  AAS04601.1  Q73XM5  268 aa hypothetical protein n.s. ●○○○○ -0.87 -0.865101345544599
Streptococcus pyogenes M1 5448  SP5448_06085  WP_002994004.1  403 aa phosphopentomutase n.s. ●○○○○ -0.86 -0.864418070079281
Streptococcus pyogenes M1 5448  SP5448_03215  WP_010922504.1  142 aa GNAT family N-acetyltransferase n.s. ●○○○○ -0.86 -0.864129669129861
Escherichia coli O157:H7 str. EDL933  Z5431  AAG59082.1  81 aa orf, hypothetical protein n.s. ●○○○○ -0.86 -0.863792888121397
Mycobacterium avium subsp. paratuberculosis K10  MAP_2296c  AAS04613.1  Q73XL3  160 aa hypothetical protein n.s. ●○○○○ -0.86 -0.863534505312985
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0278  WP_009881966.1  A0A0H3PBN2  51 aa highly acidic protein n.s. ●○○○○ -0.86 -0.862943582069
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1157  CBW17253.1  A0A0H3NAQ6  ycfX  303 aa hypothetical ROK-family protein n.s. ●○○○○ -0.86 -0.862682220207283
Escherichia coli O157:H7 str. EDL933  Z3921  AAG57736.1  159 aa hypothetical protein n.s. ●○○○○ -0.86 -0.86160120626813
Vibrio parahaemolyticus RIMD 2210633  VP_0232  BAC58495.1  Q87T38  321 aa putative carbamoylphosphate synthase large subunit, short form n.s. ●○○○○ -0.86 -0.861267231640688
Vibrio parahaemolyticus RIMD 2210633  VP_1815  BAC60078.1  Q87NQ3  142 aa hypothetical protein n.s. ●○○○○ -0.86 -0.861101069144088
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4748  AIK83282.1  575 aa PTS enzyme I n.s. ●○○○○ -0.86 -0.86108120853741
Escherichia coli M12  CO715_12610  ATI06473.1  114 aa transcriptional regulator n.s. ●○○○○ -0.86 -0.860782943562085
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1008  WP_011812755.1  A0A0H3P9G0  253 aa hypothetical protein n.s. ●○○○○ -0.86 -0.860678998489
Haemophilus influenzae Rd KW20  HI_0411  NP_438573.1  P44437  hfq  91 aa RNA-binding protein Hfq n.s. ●○○○○ -0.86 -0.860378954501662
Mycobacterium avium subsp. paratuberculosis K10  MAP_3803  AAS06353.1  Q73TB5  339 aa hypothetical protein n.s. ●○○○○ -0.86 -0.859892027810293
Mycobacterium avium subsp. paratuberculosis K10  MAP_2495  AAS04812.1  Q73X15  472 aa hypothetical protein n.s. ●○○○○ -0.86 -0.85979936092744
Escherichia coli CFT073  c2747  AAN81201.1  P0AAL1  napF  164 aa Ferredoxin-type protein napF n.s. ●○○○○ -0.86 -0.859629845061645
Mycobacterium avium subsp. paratuberculosis K10  MAP_1396  AAS03713.1  Q740F5  tyrS  421 aa TyrS n.s. ●○○○○ -0.86 -0.859573660487356
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4152  CBW20240.1  A0A0H3NKC7  104 aa hypothetical bacteriophage protein n.s. ●○○○○ -0.86 -0.859528565766288
Escherichia coli CFT073  c1112  AAN79580.1  A0A0H2V6P4  46 aa Hypothetical protein n.s. ●○○○○ -0.86 -0.859429461250795
Mycobacterium avium subsp. paratuberculosis K10  MAP_0998c  AAS03315.1  Q741T9  216 aa hypothetical protein n.s. ●○○○○ -0.86 -0.859134098576148
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3375  CBW19470.1  A0A0H3NIC9  fmu  429 aa 16S rRNA methyltransferase n.s. ●○○○○ -0.86 -0.85888178189508
Streptococcus pyogenes M1 5448  SP5448_02325  WP_002988743.1  63 aa hypothetical protein n.s. ●○○○○ -0.86 -0.858842318390505
Mycobacterium avium subsp. paratuberculosis K10  MAP_0571  AAS02888.1  Q743M0  164 aa hypothetical protein n.s. ●○○○○ -0.86 -0.858839951860223
Escherichia coli O157:H7 str. EDL933  Z3390  AAG57273.1  397 aa putative hydroxylase n.s. ●○○○○ -0.86 -0.858685335737969
Streptococcus pyogenes M1 5448  SP5448_03530  WP_002990080.1  103 aa hypothetical protein n.s. ●○○○○ -0.86 -0.858553917441085
Vibrio parahaemolyticus RIMD 2210633  VPA_1129  BAC62472.1  Q87H36  309 aa putative hydroxymethylglutaryl-CoA lyase n.s. ●○○○○ -0.86 -0.858513180141489
Escherichia coli CFT073  c1559  AAN80028.1  A0A0H2V6U9  ybcQ  132 aa Antitermination protein Q homolog from lambdoid prophage DLP12 n.s. ●○○○○ -0.86 -0.858296958807204
Serratia marcescens Strain UMH9  BVG96_12540  ASL98403.1  428 aa branched-chain amino acid ABC transporter permease n.s. ●○○○○ -0.86 -0.858250159836153
Mycobacterium avium subsp. paratuberculosis K10  MAP_3279  AAS05829.1  Q73UT7  351 aa hypothetical protein n.s. ●○○○○ -0.86 -0.857634932575315
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3457  CBW19552.1  A0A0H3NIJ2  comC  157 aa competence gene-DNA binding and transport n.s. ●○○○○ -0.86 -0.857357348716423
Mycobacterium avium subsp. paratuberculosis K10  MAP_2608  AAS04925.1  Q73WQ2  329 aa hypothetical protein n.s. ●○○○○ -0.86 -0.857188912697462
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3690  WP_000815085.1  E8XEM6  glpR  252 aa DeoR/GlpR family transcriptional regulator n.s. ●○○○○ -0.86 -0.856922978422096
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1027  WP_002856550.1  A0A0H3PAL8  466 aa potassium transporter TrkA n.s. ●○○○○ -0.86 -0.856885217031
Haemophilus influenzae Rd KW20  HI_0485  NP_438645.1  P43719  atpB  262 aa F0F1 ATP synthase subunit A n.s. ●○○○○ -0.86 -0.856819648384602
Streptococcus pyogenes M1 5448  SP5448_04110  WP_010922405.1  483 aa LytR family transcriptional regulator n.s. ●○○○○ -0.86 -0.856054442546117
Serratia marcescens Strain UMH9  BVG96_08455  ASL97644.1  429 aa MBL fold metallo-hydrolase n.s. ●○○○○ -0.86 -0.855794400690068
Escherichia coli M12  CO715_15945  ATI07071.1  233 aa NAD(P)H-flavin reductase n.s. ●○○○○ -0.86 -0.855775439220113
Escherichia coli CFT073  c0788  AAN79261.1  A0A0H2V7D0  ybgH  493 aa Hypothetical transporter ybgH n.s. ●○○○○ -0.86 -0.855340897458482
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4163  CBW20251.1  A0A0H3NIE7  malG  296 aa maltose transport inner membrane protein n.s. ●○○○○ -0.85 -0.854801153720267
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1059  WP_002853832.1  A0A0H3P9E0  110 aa hypothetical protein n.s. ●○○○○ -0.85 -0.854760742448
Mycobacterium avium subsp. paratuberculosis K10  MAP_1237c  AAS03554.1  Q740V5  drrB  246 aa DrrB n.s. ●○○○○ -0.85 -0.854457523182901
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4496  CBW20585.1  A0A0H3NQ37  deoB  407 aa phosphopentomutase n.s. ●○○○○ -0.85 -0.854317911405301
Mycobacterium avium subsp. paratuberculosis K10  MAP_0062c  AAS02379.1  Q744W1  294 aa hypothetical protein n.s. ●○○○○ -0.85 -0.854245028724129
Escherichia coli CFT073  c3744  AAN82188.1  A0A0H2VAU2  yqhC  375 aa Hypothetical transcriptional regulator yqhC n.s. ●○○○○ -0.85 -0.853887379693281
Mycobacterium avium subsp. paratuberculosis K10  MAP_2609  AAS04926.1  Q73WQ1  110 aa hypothetical protein n.s. ●○○○○ -0.85 -0.853740714935706
Mycobacterium avium subsp. paratuberculosis K10  MAP_2610c  AAS04927.1  Q73WQ0  239 aa hypothetical protein n.s. ●○○○○ -0.85 -0.853740714935706
Serratia marcescens Strain UMH9  BVG96_06090  ASL97210.1  344 aa phosphate acyltransferase n.s. ●○○○○ -0.85 -0.853727591319888
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2915  CBW19014.1  A0A0H3NFE3  iap  348 aa alkaline phosphatase isozyme conversion protein n.s. ●○○○○ -0.85 -0.853033374810238
Haemophilus influenzae Rd KW20  HI_0621  NP_438780.1  P44785  metN  345 aa DL-methionine transporter ATP-binding protein n.s. ●○○○○ -0.85 -0.853026396894352
Escherichia coli CFT073  c2075  AAN80535.1  Q8FH54  sufS  406 aa Selenocysteine lyase n.s. ●○○○○ -0.85 -0.852262486386215
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2182  CBW18278.1  A0A0H3NF07  fruK  285 aa 1-phosphofructokinase n.s. ●○○○○ -0.85 -0.852164580079413
Escherichia coli CFT073  c3125  AAN81575.1  A0A0H2VB57  yfiN  408 aa Hypothetical protein yfiN n.s. ●○○○○ -0.85 -0.852096931382374
Escherichia coli CFT073  c0925  AAN79398.1  P0ACK6  deoR  252 aa Deoxyribose operon repressor n.s. ●○○○○ -0.85 -0.851957800151705
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1357  CBW17453.1  A0A0H3NB15  norM  457 aa Probable multidrug resistance protein norM n.s. ●○○○○ -0.85 -0.851519002199265
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0832  CBW16929.1  A0A0H3NB66  315 aa hypothetical electron transfer flavoprotein (alpha subunit) n.s. ●○○○○ -0.85 -0.851358625063002
Escherichia coli O157:H7 str. EDL933  Z0478  AAG54728.1  86 aa orf, hypothetical protein n.s. ●○○○○ -0.85 -0.851126010584594
Escherichia coli CFT073  c2834  AAN81288.1  A0A0H2V958  yfbT  216 aa Protein yfbT n.s. ●○○○○ -0.85 -0.851111233901357
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2492  CBW18593.2  A0A0H3NPR0  792 aa dimethyl sulfoxide reductase n.s. ●○○○○ -0.85 -0.85099449314779
Serratia marcescens Strain UMH9  BVG96_16780  ASL99175.1  515 aa polynucleotide adenylyltransferase n.s. ●○○○○ -0.85 -0.850836373656786
Haemophilus influenzae Rd KW20  HI_0029  NP_438202.1  P44466  dacA  393 aa penicillin-binding protein 5 n.s. ●○○○○ -0.85 -0.850824865204942
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0880  WP_002857195.1  A0A0H3PA35  dsbA  220 aa thiol:disulfide interchange protein DsbA/DsbL n.s. ●○○○○ -0.85 -0.850731395922
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