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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3619  CBW19712.1  A0A0H3NHA0  yafP  155 aa hypothetical acetyltransferase n.s. ●○○○○ -0.85 -0.850261751279277
Escherichia coli CFT073  c1734  AAN80200.1  Q8FHV4  rluB  291 aa Hypothetical protein yciL n.s. ●○○○○ -0.85 -0.850064131564138
Serratia marcescens Strain UMH9  BVG96_20960  ASL99938.1  777 aa DNA primase n.s. ●○○○○ -0.85 -0.85002667005599
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3589  CBW19683.1  A0A0H3NTG2  yhjU  559 aa hypothetical membrane protein n.s. ●○○○○ -0.85 -0.849940060310639
Escherichia coli CFT073  c3071  AAN81521.1  A0A0H2V9L6  yphG  1124 aa Hypothetical protein yphG n.s. ●○○○○ -0.85 -0.849802280155598
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0370  CBW16470.1  A0A0H3N9S9  ampH  376 aa penicillin-binding protein AmpH n.s. ●○○○○ -0.85 -0.849718923188082
Streptococcus pyogenes M1 5448  SP5448_03690  WP_010922456.1  197 aa tail protein n.s. ●○○○○ -0.85 -0.849709621658889
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0142  CBW16245.1  A0A0H3N805  pilC  400 aa competence gene-DNA binding and transport n.s. ●○○○○ -0.85 -0.849695734792278
Streptococcus pyogenes M1 5448  SP5448_07600  WP_010921966.1  590 aa oleate hydratase n.s. ●○○○○ -0.85 -0.849325087059663
Serratia marcescens Strain UMH9  BVG96_21280  ASL99991.1  398 aa protoheme IX biogenesis protein HemY n.s. ●○○○○ -0.85 -0.849113862139095
Streptococcus pyogenes M1 5448  SP5448_05325  WP_010922297.1  242 aa ABC transporter ATP-binding protein n.s. ●○○○○ -0.85 -0.848748285160824
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0899  WP_002869170.1  A0A0H3PDF2  220 aa response regulator transcription factor n.s. ●○○○○ -0.85 -0.848560561758
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2763  CBW18862.1  A0A0H3NF08  pipB2  350 aa Type III secretion system effector protein, Contributes to Sif formation n.s. ●○○○○ -0.85 -0.848505349677807
Escherichia coli CFT073  c0616  AAN79093.1  A0A0H2V4Y9  ybbA  228 aa Hypothetical ABC transporter ATP-binding protein ybbA n.s. ●○○○○ -0.85 -0.848230534239312
Porphyromonas gingivalis ATCC 33277  PGN_1807  WP_012458546.1  B2RLT1  336 aa glycosyltransferase n.s. ●○○○○ -0.85 -0.848158879915347
Mycobacterium avium subsp. paratuberculosis K10  MAP_2628c  AAS04945.1  Q73WN2  191 aa hypothetical protein n.s. ●○○○○ -0.85 -0.847743420441694
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0964  WP_002853965.1  A0A0H3P9I2  261 aa amino acid ABC transporter permease n.s. ●○○○○ -0.85 -0.847463545139
Escherichia coli CFT073  c3070  AAN81520.1  A0A0H2VC11  yphF  327 aa ABC transporter Periplasmic binding protein yphF precursor n.s. ●○○○○ -0.85 -0.847439111160349
Mycobacterium avium subsp. paratuberculosis K10  MAP_1736  AAS04053.1  Q73Z67  202 aa hypothetical protein n.s. ●○○○○ -0.85 -0.847345028137652
Mycobacterium avium subsp. paratuberculosis K10  MAP_3555  AAS06105.1  Q73U13  168 aa hypothetical protein n.s. ●○○○○ -0.85 -0.847207334596258
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3869  CBW19958.1  A0A0H3NUB6  ilvC  491 aa ketol-acid reductoisomerase n.s. ●○○○○ -0.85 -0.847090078189472
Mycobacterium avium subsp. paratuberculosis K10  MAP_3105  AAS05653.1  Q73VA9  204 aa hypothetical protein n.s. ●○○○○ -0.85 -0.847030385830011
Escherichia coli CFT073  c3228  AAN81680.1  A0A0H2VCA4  nrdE  714 aa Ribonucleoside-diphosphate reductase 2 alpha chain n.s. ●○○○○ -0.85 -0.847025570958892
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0319  CBW16420.1  A0A0H3NDB0  266 aa hypothetical IS3 transposase n.s. ●○○○○ -0.85 -0.846747953670529
Mycobacterium avium subsp. paratuberculosis K10  MAP_1604c  AAS03921.1  Q73ZJ9  lppE  140 aa LppE n.s. ●○○○○ -0.85 -0.846707190691841
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0257  CBW16359.1  A0A0H3ND20  yafS  240 aa conserved hypothetical protein n.s. ●○○○○ -0.85 -0.846561158347483
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1645  WP_002868875.1  A1W1Q6  nhaA1  389 aa Na+/H+ antiporter NhaA n.s. ●○○○○ -0.85 -0.846555897546
Mycobacterium avium subsp. paratuberculosis K10  MAP_4178  AAS06728.1  P60742  rplX  105 aa RplX n.s. ●○○○○ -0.85 -0.846506083340155
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0275  CBW16376.1  A0A0H3NHR2  sciN  178 aa lipoprotein (SPI-6 associated) n.s. ●○○○○ -0.85 -0.846345826299859
Vibrio parahaemolyticus RIMD 2210633  VPA_1487  BAC62830.1  Q87G30  166 aa putative acetyltransferase n.s. ●○○○○ -0.85 -0.846296450942946
Streptococcus pyogenes M1 5448  SP5448_02270  WP_002988708.1  99 aa hypothetical protein n.s. ●○○○○ -0.85 -0.846152676616049
Mycobacterium avium subsp. paratuberculosis K10  MAP_2818c  AAS05135.1  Q73W42  suhB  292 aa SuhB n.s. ●○○○○ -0.85 -0.846024110752807
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3769  CBW19859.1  A0A0H3NJ99  dsdX  445 aa DsdX permease n.s. ●○○○○ -0.85 -0.845777546444394
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0625  WP_002856965.1  A1VYV7  fba  354 aa class II fructose-bisphosphate aldolase n.s. ●○○○○ -0.85 -0.845738106772
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1415  WP_002869138.1  A0A0H3PBC8  253 aa sugar nucleotidyltransferase n.s. ●○○○○ -0.85 -0.845470624542
Vibrio parahaemolyticus RIMD 2210633  VP_2947  BAC61210.1  Q87KN0  plsB  808 aa glycerol-3-phosphate acyltransferase n.s. ●○○○○ -0.85 -0.845075689695024
Vibrio parahaemolyticus RIMD 2210633  VPA_1165  BAC62508.1  Q87H00  192 aa hypothetical protein n.s. ●○○○○ -0.85 -0.845047015392829
Escherichia coli CFT073  c2596  AAN81052.1  A0A0H2V8N3  yegD  471 aa Hypothetical chaperone protein yegD n.s. ●○○○○ -0.84 -0.844933803415604
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3498  CBW19592.1  A0A0H3NH13  571 aa hypothetical dehydratase n.s. ●○○○○ -0.84 -0.844708753073534
Mycobacterium avium subsp. paratuberculosis K10  MAP_1362  AAS03679.1  P62063  argJ  404 aa ArgJ n.s. ●○○○○ -0.84 -0.844642004796589
Streptococcus pyogenes M1 5448  SP5448_02130  WP_010922588.1  303 aa PTS mannose/fructose/sorbose transporter family subunit IID n.s. ●○○○○ -0.84 -0.844518404569339
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1373  WP_002869334.1  A0A0H3P9Z1  147 aa nicotinate phosphoribosyltransferase n.s. ●○○○○ -0.84 -0.844223348609
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1079  WP_000938191.1  E8XE43  pipA  226 aa type III secretion system effector protease PipA n.s. ●○○○○ -0.84 -0.843826067810091
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0818  CBW16915.1  A0A0H3N9E5  ybiV(1)  269 aa conserved hypothetical protein n.s. ●○○○○ -0.84 -0.843666876502342
Mycobacterium avium subsp. paratuberculosis K10  MAP_2255  AAS04572.1  Q73XQ4  415 aa hypothetical protein n.s. ●○○○○ -0.84 -0.843597799886552
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1567  WP_079254196.1  A0A0H3PDX4  264 aa ABC transporter permease n.s. ●○○○○ -0.84 -0.843265580488
Escherichia coli CFT073  c2080  AAN80540.1  A0A0H2V8Y6  ydiH  89 aa Hypothetical protein ydiH n.s. ●○○○○ -0.84 -0.842822149052112
Vibrio parahaemolyticus RIMD 2210633  VPA_0805  BAC62148.1  Q87I01  372 aa glycine cleavage system protein T2 n.s. ●○○○○ -0.84 -0.842528434137934
Mycobacterium avium subsp. paratuberculosis K10  MAP_0118  AAS02435.1  Q745B5  122 aa hypothetical protein n.s. ●○○○○ -0.84 -0.842329624833266
Vibrio parahaemolyticus RIMD 2210633  VPA_0697  BAC62040.1  Q87IA9  327 aa putative nonspecific acid phosphatase precursor n.s. ●○○○○ -0.84 -0.842192605685664
Mycobacterium avium subsp. paratuberculosis K10  MAP_0574  AAS02891.1  Q743L7  pstB  222 aa PstB n.s. ●○○○○ -0.84 -0.842145821272071
Streptococcus pyogenes M1 5448  SP5448_00570  WP_010921792.1  271 aa ABC transporter permease n.s. ●○○○○ -0.84 -0.842115063324177
Streptococcus pyogenes M1 5448  SP5448_02605  WP_010922567.1  543 aa Na/Pi cotransporter family protein n.s. ●○○○○ -0.84 -0.841730528724951
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3096  CBW19195.1  A0A0H3NFX8  579 aa arylsulfatase n.s. ●○○○○ -0.84 -0.84154202168248
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1776  CBW17870.1  A0A0H3NHN9  yebR  194 aa conserved hypothetical protein n.s. ●○○○○ -0.84 -0.841455027482369
Mycobacterium avium subsp. paratuberculosis K10  MAP_0032c  AAS02349.1  Q744S3  fadE25  460 aa FadE25_1 n.s. ●○○○○ -0.84 -0.841420941472663
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3873  CBW19963.1  A0A0H3NND3  gppA  493 aa guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase (guanosine pentaphosphatase) n.s. ●○○○○ -0.84 -0.841319705686553
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1364  CBW17460.1  A0A0H3NB96  ydhO  284 aa hypothetical secreted protein n.s. ●○○○○ -0.84 -0.841075676966785
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2762  CBW18861.1  A0A0H3NKY8  iroN  726 aa TonB-dependent outer membrane siderophore receptor protein n.s. ●○○○○ -0.84 -0.840975137337684
Escherichia coli M12  CO715_10565  ATI06101.1  231 aa electron transporter RsxE n.s. ●○○○○ -0.84 -0.840961572208443
Mycobacterium avium subsp. paratuberculosis K10  MAP_4081  AAS06631.1  Q73SJ2  236 aa hypothetical protein n.s. ●○○○○ -0.84 -0.840649268766416
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1359  CBW17455.1  A0A0H3NB92  cfa  382 aa cyclopropane-fatty-acyl-phospholipid synthase n.s. ●○○○○ -0.84 -0.840430520540739
Haemophilus influenzae Rd KW20  HI_1004  NP_439165.2  P44092  ppiD  622 aa peptidyl-prolyl cis-trans isomerase n.s. ●○○○○ -0.84 -0.840423757906453
Streptococcus pyogenes M1 5448  SP5448_04410  WP_011285581.1  260 aa DNA replication protein n.s. ●○○○○ -0.84 -0.840096256678241
Acinetobacter baumannii ATCC 17978  A1S_1973  ABO12400.2  250 aa undecaprenyl pyrophosphate synthetase n.s. ●○○○○ -0.84 -0.840083445984053
Streptococcus pyogenes M1 5448  SP5448_08890  WP_002982334.1  63 aa hypothetical protein n.s. ●○○○○ -0.84 -0.839807855728822
Streptococcus pyogenes M1 5448  SP5448_08890  WP_002982339.1  126 aa RidA family protein n.s. ●○○○○ -0.84 -0.839807855728822
Escherichia coli CFT073  c3111  AAN81560.1  A0A0H2V9N4  yfiM  114 aa Hypothetical protein yfiM n.s. ●○○○○ -0.84 -0.839795316416291
Vibrio parahaemolyticus RIMD 2210633  VPA_0995  BAC62338.1  Q87HH0  310 aa hypothetical protein n.s. ●○○○○ -0.84 -0.83935883551114
Vibrio parahaemolyticus RIMD 2210633  VP_1700  BAC59963.1  Q87P18  138 aa putative lipoprotein VirG (YscW) n.s. ●○○○○ -0.84 -0.839343990027283
Serratia marcescens Strain UMH9  BVG96_06115  ASL97214.1  413 aa beta-ketoacyl-[acyl-carrier-protein] synthase II n.s. ●○○○○ -0.84 -0.838594060127391
Mycobacterium avium subsp. paratuberculosis K10  MAP_2228  AAS04545.1  Q73XT1  368 aa hypothetical protein n.s. ●○○○○ -0.84 -0.838517929630623
Escherichia coli O157:H7 str. EDL933  Z0415  AAG54669.1  328 aa putative periplasmic binding protein, probable substrate ribose n.s. ●○○○○ -0.84 -0.838435212255642
Escherichia coli O157:H7 str. EDL933  Z2338  AAG56387.1  209 aa unknown protein encoded by prophage CP-933R n.s. ●○○○○ -0.84 -0.83793804999425
Mycobacterium avium subsp. paratuberculosis K10  MAP_0093  AAS02410.1  Q744Z6  175 aa hypothetical protein n.s. ●○○○○ -0.84 -0.837382838425953
Mycobacterium avium subsp. paratuberculosis K10  MAP_3833c  AAS06383.1  Q73T85  260 aa hypothetical protein n.s. ●○○○○ -0.84 -0.837344046750799
Escherichia coli CFT073  c2766  AAN81220.1  A0A0H2VBD0  atoE  440 aa Short-chain fatty acids transporter n.s. ●○○○○ -0.84 -0.837339387478628
Vibrio parahaemolyticus RIMD 2210633  VPA_0654  BAC61996.1  Q87IF3  153 aa hypothetical protein n.s. ●○○○○ -0.84 -0.837202475940114
Serratia marcescens Strain UMH9  BVG96_09580  ASL97859.1  644 aa exoribonuclease II n.s. ●○○○○ -0.84 -0.836900728506491
Streptococcus pyogenes M1 5448  SP5448_03055  WP_011285650.1  574 aa sensor histidine kinase n.s. ●○○○○ -0.84 -0.836827712584821
Serratia marcescens Strain UMH9  BVG96_07975  ASL97557.1  318 aa iron dicitrate transport regulator FecR n.s. ●○○○○ -0.84 -0.836755043009564
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0007  WP_002869297.1  A1W1W6  rlmN  356 aa 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN n.s. ●○○○○ -0.84 -0.836716523013
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0007  WP_002869298.1  A1W1W6  rlmN  32 aa hypothetical protein n.s. ●○○○○ -0.84 -0.836716523013
Escherichia coli CFT073  c2935  AAN81385.1  A0A0H2V9G7  yfeD  130 aa Hypothetical protein yfeD n.s. ●○○○○ -0.84 -0.836670874360647
Escherichia coli CFT073  c2028  AAN80488.1  Q8FH89  pdxY  287 aa Pyridoxamine kinase n.s. ●○○○○ -0.84 -0.836670874360638
Escherichia coli O157:H7 str. EDL933  Z4932  AAG58660.1  549 aa cytoplasmic trehalase n.s. ●○○○○ -0.84 -0.836650378353322
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0574  CBW16674.1  A0A0H3NAE0  fes  404 aa enterochelin esterase n.s. ●○○○○ -0.84 -0.836426136605133
Escherichia coli M12  CO715_05015  ATI05149.1  245 aa 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase n.s. ●○○○○ -0.84 -0.836371359894968
Escherichia coli CFT073  c2546  AAN81001.1  P60758  hisG  299 aa ATP phosphoribosyltransferase n.s. ●○○○○ -0.84 -0.835914925673582
Mycobacterium avium subsp. paratuberculosis K10  MAP_3494  AAS06044.1  Q73U74  468 aa hypothetical protein n.s. ●○○○○ -0.84 -0.83564349910774
Streptococcus pyogenes M1 5448  SP5448_06155  WP_010922166.1  297 aa mevalonate kinase n.s. ●○○○○ -0.84 -0.835385707837723
Serratia marcescens Strain UMH9  BVG96_14940  ASL98845.1  396 aa flavohemoprotein n.s. ●○○○○ -0.84 -0.835379735842046
Acinetobacter baumannii ATCC 17978  A1S_0020  ABO10517.2  945 aa isoleucyl-tRNA synthetase n.s. ●○○○○ -0.84 -0.835259411787944
Serratia marcescens Strain UMH9  BVG96_00035  ASL96096.1  317 aa transaldolase n.s. ●○○○○ -0.84 -0.835120899077237
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0617  WP_011812722.1  A0A0H3PBC4  284 aa bifunctional riboflavin kinase/FAD synthetase n.s. ●○○○○ -0.83 -0.834982592143
Serratia marcescens Strain UMH9  BVG96_08690  ASL97687.1  340 aa hydrolase n.s. ●○○○○ -0.83 -0.834767759619467
Escherichia coli M12  CO715_09570  ATI05933.1  391 aa 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase n.s. ●○○○○ -0.83 -0.833867607723982
Escherichia coli CFT073  c2763  AAN81217.1  A0A0H2VAG3  atoC  461 aa Acetoacetate metabolism Regulatory protein atoC n.s. ●○○○○ -0.83 -0.833865276757752
Escherichia coli O157:H7 str. EDL933  Z2041  AAG56117.1  135 aa unknown protein encoded by prophage CP-933O n.s. ●○○○○ -0.83 -0.833581007374695
Escherichia coli CFT073  c2975  AAN81425.1  A0A0H2VBS3  eutB  453 aa Ethanolamine ammonia-lyase heavy chain n.s. ●○○○○ -0.83 -0.833507950710851
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