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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Vibrio parahaemolyticus RIMD 2210633  VP_0325  BAC58588.1  Q87SU7  mdh  311 aa malate dehydrogenase n.s. ●○○○○ -0.44 -0.439863540358241
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1637  CBW17732.1  A0A0H3NBT9  osmB  72 aa osmotically inducible lipoprotein B precursor n.s. ●○○○○ -0.44 -0.439833005690789
Streptococcus pyogenes M1 5448  SP5448_01910  WP_002995381.1  340 aa iron ABC transporter permease n.s. ●○○○○ -0.44 -0.439795738884058
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2574  CBW18675.1  A0A0H3NEH6  133 aa predicted bacteriophage protein n.s. ●○○○○ -0.44 -0.439461575761109
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0941  CBW17037.1  A0A0H3N9U2  pncB  400 aa nicotinate phosphoribosyltransferase (ec 2.4.2.11) (naprtase) n.s. ●○○○○ -0.44 -0.439448695565842
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4468  CBW20557.1  A0A0H3NWD8  259 aa PTS transport system, IIC component n.s. ●○○○○ -0.44 -0.439341536363837
Mycobacterium avium subsp. paratuberculosis K10  MAP_2528  AAS04845.1  Q73WY2  282 aa hypothetical protein n.s. ●○○○○ -0.44 -0.439179238681592
Haemophilus influenzae Rd KW20  HI_1430  NP_439579.1  P45200  252 aa short chain dehydrogenase/reductase n.s. ●○○○○ -0.44 -0.439134322068055
Escherichia coli CFT073  c4714  AAN83147.1  Q8FBP9  wecF  359 aa 4-alpha-L-fucosyltransferase n.s. ●○○○○ -0.44 -0.439133525971585
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0907  CBW17003.1  A0A0H3NEY8  pflA  274 aa pyruvate formate-lyase 1 activating enzyme n.s. ●○○○○ -0.44 -0.439096742353427
Mycobacterium avium subsp. paratuberculosis K10  MAP_3768c  AAS06318.1  Q73TF0  rpsN  101 aa RpsN2 n.s. ●○○○○ -0.44 -0.438928982526263
Escherichia coli O157:H7 str. EDL933  Z0077  AAG54372.1  327 aa thiamin-binding periplasmic protein n.s. ●○○○○ -0.44 -0.438809086137292
Vibrio parahaemolyticus RIMD 2210633  VPA_0480  BAC61823.1  Q87IX6  1046 aa putative cation efflux system transmembrane protein n.s. ●○○○○ -0.44 -0.438778666572888
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0755  WP_002776579.1  A0A0H3PHL4  329 aa ABC transporter ATP-binding protein n.s. ●○○○○ -0.44 -0.438776297389
Streptococcus pyogenes M1 5448  SP5448_01070  WP_010921856.1  410 aa hypothetical protein n.s. ●○○○○ -0.44 -0.438738268736187
Mycobacterium avium subsp. paratuberculosis K10  MAP_3832c  AAS06382.1  Q73T86  565 aa hypothetical protein n.s. ●○○○○ -0.44 -0.438488945160683
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1445  WP_002819467.1  A0A0H3PBH3  237 aa membrane protein n.s. ●○○○○ -0.44 -0.437971819306
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2403  CBW18505.1  A0A0H3NE51  cysM  303 aa cysteine synthase B n.s. ●○○○○ -0.44 -0.43772246443197
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4254  CBW20340.1  A0A0H3NKN6  163 aa Putative acetyltransferase n.s. ●○○○○ -0.44 -0.437468067858861
Escherichia coli CFT073  c3192  AAN81644.1  P0AD36  yfdO  313 aa Unknown protein encoded by cryptic prophage n.s. ●○○○○ -0.44 -0.437387099116785
Serratia marcescens Strain UMH9  BVG96_18400  ASM00598.1  445 aa gluconate transporter n.s. ●○○○○ -0.44 -0.437300972010863
Vibrio parahaemolyticus RIMD 2210633  VP_1140  BAC59403.1  Q87QK9  hisB  357 aa imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase n.s. ●○○○○ -0.44 -0.437298430010215
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4375  CBW20463.1  A0A0H3NW39  377 aa hypothetical protein n.s. ●○○○○ -0.44 -0.437210301524123
Serratia marcescens Strain UMH9  BVG96_07725  ASL97508.1  213 aa endonuclease III n.s. ●○○○○ -0.44 -0.43704252602463
Vibrio parahaemolyticus RIMD 2210633  VPA_1230  BAC62573.1  Q87GT5  477 aa glyceraldehyde 3-phosphate dehydrogenase n.s. ●○○○○ -0.44 -0.436929756647644
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3195  CBW19293.1  A0A0H3NS43  ygjQ  230 aa conserved hypothetical protein n.s. ●○○○○ -0.44 -0.436919510735632
Vibrio parahaemolyticus RIMD 2210633  VPA_0971  BAC62314.1  Q87HJ2  fabH2  364 aa 3-oxoacyl-(acyl-carrier-protein) synthase III n.s. ●○○○○ -0.44 -0.436781455796019
Mycobacterium avium subsp. paratuberculosis K10  MAP_3928c  AAS06478.1  Q73SZ4  722 aa hypothetical protein n.s. ●○○○○ -0.44 -0.436588651778024
Streptococcus pyogenes M1 5448  SP5448_02985  WP_009880741.1  258 aa recombination regulator RecX n.s. ●○○○○ -0.44 -0.436527194790638
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0573  CBW16673.1  A0A0H3NIQ4  fepA  751 aa ferrienterobactin receptor precursor n.s. ●○○○○ -0.44 -0.436343639843759
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4414  CBW20502.1  A0A0H3NPW0  idnD  343 aa l-idonate 5-dehydrogenase (ec 1.1.1.264) n.s. ●○○○○ -0.44 -0.436223919769915
Vibrio parahaemolyticus RIMD 2210633  VPA_1143  BAC62486.1  Q87H22  437 aa putative molybdenum containing oxidoreductase n.s. ●○○○○ -0.44 -0.436213875459105
Escherichia coli CFT073  c0622  AAN79099.1  A0A0H2V720  gcl  623 aa Glyoxylate carboligase n.s. ●○○○○ -0.44 -0.43620048392603
Serratia marcescens Strain UMH9  BVG96_10045  ASL97940.1  214 aa hypothetical protein n.s. ●○○○○ -0.44 -0.436152519893321
Mycobacterium avium subsp. paratuberculosis K10  MAP_3939c  AAS06489.1  Q73SY4  214 aa hypothetical protein n.s. ●○○○○ -0.44 -0.435941143898004
Serratia marcescens Strain UMH9  BVG96_06460  ASL97277.1  1029 aa beta-galactosidase subunit alpha n.s. ●○○○○ -0.44 -0.435903373383523
Haemophilus influenzae Rd KW20  HI_0539  NP_438697.1  P44391  ureC  572 aa urease subunit alpha n.s. ●○○○○ -0.44 -0.43587076940071
Serratia marcescens Strain UMH9  BVG96_19060  ASL99595.1  777 aa RNA-binding transcriptional accessory protein n.s. ●○○○○ -0.44 -0.435629736419579
Mycobacterium avium subsp. paratuberculosis K10  MAP_2537  AAS04854.1  Q73WX3  274 aa hypothetical protein n.s. ●○○○○ -0.44 -0.435503441656612
Streptococcus pyogenes M1 5448  SP5448_02185  WP_010922583.1  344 aa ABC transporter permease n.s. ●○○○○ -0.44 -0.435469724642766
Streptococcus pyogenes M1 5448  SP5448_07165  WP_010922016.1  620 aa PTS beta-glucoside transporter subunit IIBCA n.s. ●○○○○ -0.44 -0.435277457343153
Mycobacterium avium subsp. paratuberculosis K10  MAP_0532  AAS02849.1  Q743Q9  305 aa hypothetical protein n.s. ●○○○○ -0.44 -0.435187553241767
Mycobacterium avium subsp. paratuberculosis K10  MAP_2411  AAS04728.1  Q73X98  142 aa hypothetical protein n.s. ●○○○○ -0.44 -0.435064749127088
Vibrio parahaemolyticus RIMD 2210633  VP_1906  BAC60169.1  Q87NG2  158 aa transcriptional regulator, MarR family n.s. ●○○○○ -0.44 -0.435013704520564
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0408  WP_002854544.1  A0A0H3PF38  310 aa EamA family transporter n.s. ●○○○○ -0.43 -0.434975766618
Vibrio parahaemolyticus RIMD 2210633  VP_2564  BAC60827.1  Q87LP7  739 aa GTP pyrophosphokinase n.s. ●○○○○ -0.43 -0.434518349483745
Vibrio parahaemolyticus RIMD 2210633  VP_2842  BAC61105.1  Q87KY2  frdC  127 aa fumarate reductase, 15 kDa hydrophobic protein n.s. ●○○○○ -0.43 -0.434277814006711
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2741  CBW18841.1  A0A0H3NQI3  280 aa hypothetical glucose-6-phosphate isomerase n.s. ●○○○○ -0.43 -0.434187182491457
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1621  CBW17716.1  A0A0H3NDD4  pspF  326 aa psp operon transcriptional activator PspF n.s. ●○○○○ -0.43 -0.434130867016941
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3744  CBW19835.1  A0A0H3NHI4  107 aa hypothetical DNA-binding protein n.s. ●○○○○ -0.43 -0.433987810989134
Serratia marcescens Strain UMH9  BVG96_07880  ASL97538.1  428 aa hypothetical protein n.s. ●○○○○ -0.43 -0.433978451836594
Serratia marcescens Strain UMH9  BVG96_10640  ASL98048.1  189 aa hypothetical protein n.s. ●○○○○ -0.43 -0.433820763388334
Acinetobacter baumannii ATCC 17978  A1S_2167  ABO12594.2  663 aa cytochrome o ubiquinol oxidase subunit I n.s. ●○○○○ -0.43 -0.433644126222415
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2045  CBW18141.1  A0A0H3NN57  yeeF  454 aa hypothetical amino acid transporter protein n.s. ●○○○○ -0.43 -0.433244147109952
Serratia marcescens Strain UMH9  BVG96_08145  ASL97590.1  434 aa alcohol dehydrogenase n.s. ●○○○○ -0.43 -0.433176586804527
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0591  WP_001031461.1  E8X942  909 aa sigma-54-dependent transcriptional regulator n.s. ●○○○○ -0.43 -0.433156662274016
Mycobacterium avium subsp. paratuberculosis K10  MAP_3737  AAS06287.1  Q73TI1  504 aa hypothetical protein n.s. ●○○○○ -0.43 -0.433144904214282
Vibrio parahaemolyticus RIMD 2210633  VPA_0801  BAC62144.1  Q87I05  gcvP  954 aa glycine cleavage system P protein n.s. ●○○○○ -0.43 -0.433139220485973
Mycobacterium avium subsp. paratuberculosis K10  MAP_3597  AAS06147.1  Q73TX1  161 aa hypothetical protein n.s. ●○○○○ -0.43 -0.432846133910032
Acinetobacter baumannii ATCC 17978  A1S_2681  ABO13094.2  631 aa cell division protein n.s. ●○○○○ -0.43 -0.43272377628594
Vibrio parahaemolyticus RIMD 2210633  VPA_0788  BAC62131.1  Q87I18  312 aa putative outer membrane phospholipase A precursor n.s. ●○○○○ -0.43 -0.432542458155498
Serratia marcescens Strain UMH9  BVG96_12400  ASL98377.1  190 aa hypothetical protein n.s. ●○○○○ -0.43 -0.432402548235918
Vibrio parahaemolyticus RIMD 2210633  VP_1198  BAC59461.1  Q87QF1  256 aa putative reductase n.s. ●○○○○ -0.43 -0.43238946554073
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0487  WP_002868792.1  A0A0H3PJ06  mqnC  348 aa dehypoxanthine futalosine cyclase n.s. ●○○○○ -0.43 -0.432382177183
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2630  CBW18732.1  A0A0H3NEN4  yfiN  406 aa hypothetical membrane protein n.s. ●○○○○ -0.43 -0.432358556567117
Serratia marcescens Strain UMH9  BVG96_20655  ASL99885.1  552 aa transporter n.s. ●○○○○ -0.43 -0.432300884546136
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0345  WP_002868751.1  A0A0H3PJG1  398 aa hypothetical protein n.s. ●○○○○ -0.43 -0.432041850092
Escherichia coli CFT073  c2678  AAN81134.1  P64537  yeiS  79 aa Hypothetical protein yeiS n.s. ●○○○○ -0.43 -0.43194853802662
Serratia marcescens Strain UMH9  BVG96_04335  ASL96876.1  318 aa isoaspartyl peptidase/L-asparaginase n.s. ●○○○○ -0.43 -0.4319220828592
Streptococcus pyogenes M1 5448  SP5448_03165  WP_002983776.1  236 aa cytochrome c biogenesis protein CcdA n.s. ●○○○○ -0.43 -0.431912779599927
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4464  CBW20553.1  A0A0H3NL96  tsr  553 aa methyl-accepting chemotaxis protein n.s. ●○○○○ -0.43 -0.431276676727261
Streptococcus pyogenes M1 5448  SP5448_00575  WP_010921793.1  127 aa HIT family protein n.s. ●○○○○ -0.43 -0.431239844051281
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1206  WP_000529340.1  E8XEX7  nagZ  341 aa beta-N-acetylhexosaminidase n.s. ●○○○○ -0.43 -0.431202525115326
Mycobacterium avium subsp. paratuberculosis K10  MAP_2181c  AAS04498.1  Q73XX7  228 aa hypothetical protein n.s. ●○○○○ -0.43 -0.431166802478967
Escherichia coli CFT073  c3030  AAN81480.1  A0A0H2V9H3  325 aa SinI homolog n.s. ●○○○○ -0.43 -0.430953421947621
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3976  WP_000543314.1  E8XHN6  dsdX  445 aa D-serine transporter DsdX n.s. ●○○○○ -0.43 -0.430945376563543
Escherichia coli CFT073  c1465  AAN79934.1  A0A0H2V7I6  204 aa Putative tail assembly protein of cryptic prophage n.s. ●○○○○ -0.43 -0.430813333391987
Streptococcus pyogenes M1 5448  SP5448_09020  WP_010922745.1  542 aa alpha,alpha-phosphotrehalase n.s. ●○○○○ -0.43 -0.430759175802249
Streptococcus pyogenes M1 5448  SP5448_04330  WP_002992583.1  339 aa LacI family transcriptional regulator n.s. ●○○○○ -0.43 -0.430663042152442
Vibrio parahaemolyticus RIMD 2210633  VP_2437  BAC60700.1  Q87M21  427 aa NupC family protein n.s. ●○○○○ -0.43 -0.430576728480172
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2170  AIK80775.1  561 aa FAD binding domain protein n.s. ●○○○○ -0.43 -0.430518299120578
Serratia marcescens Strain UMH9  BVG96_05680  ASL97133.1  100 aa antibiotic biosynthesis monooxygenase n.s. ●○○○○ -0.43 -0.430489065127992
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0465  WP_002857284.1  A0A0H3PAG3  sdhC  285 aa heterodisulfide reductase subunit B n.s. ●○○○○ -0.43 -0.430340861602
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1542  CBW17637.1  A0A0H3NBU2  372 aa conserved hypothetical protein n.s. ●○○○○ -0.43 -0.430327104129781
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3040  CBW19139.1  A0A0H3NHM7  iciA  297 aa chromosome intitiation inhibitor n.s. ●○○○○ -0.43 -0.430219384132458
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1235  WP_002868856.1  A0A0H3PE96  396 aa HAMP domain-containing histidine kinase n.s. ●○○○○ -0.43 -0.430209573961
Mycobacterium avium subsp. paratuberculosis K10  MAP_2359c  AAS04676.1  Q73XF0  496 aa hypothetical protein n.s. ●○○○○ -0.43 -0.430093141227558
Serratia marcescens Strain UMH9  BVG96_01600  ASL96377.1  1083 aa exonuclease subunit SbcC n.s. ●○○○○ -0.43 -0.430085248732019
Serratia marcescens Strain UMH9  BVG96_22825  ASM00268.1  535 aa glucose-methanol-choline oxidoreductase n.s. ●○○○○ -0.43 -0.429986967557348
Serratia marcescens Strain UMH9  BVG96_07840  ASL97530.1  510 aa GTP-binding protein n.s. ●○○○○ -0.43 -0.429977405956578
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0490  CBW16590.1  A0A0H3NII0  275 aa probable secreted protein n.s. ●○○○○ -0.43 -0.42993665150965
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0605  WP_002854771.1  A1VYT7  queA  342 aa tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA n.s. ●○○○○ -0.43 -0.429473689037
Mycobacterium avium subsp. paratuberculosis K10  MAP_1232  AAS03549.1  Q740W0  epiA  320 aa EpiA n.s. ●○○○○ -0.43 -0.42939879769385
Acinetobacter baumannii ATCC 17978  A1S_2322  ABO12744.1  A3M750  tsf  291 aa protein chain elongation factor EF-Ts n.s. ●○○○○ -0.43 -0.429313929157445
Mycobacterium avium subsp. paratuberculosis K10  MAP_0810  AAS03127.1  Q742M5  cspB  138 aa CspB n.s. ●○○○○ -0.43 -0.429186780809533
Serratia marcescens Strain UMH9  BVG96_16305  ASL99087.1  223 aa allulose-6-phosphate 3-epimerase n.s. ●○○○○ -0.43 -0.429050126647874
Serratia marcescens Strain UMH9  BVG96_13645  ASL98608.1  268 aa hypothetical protein n.s. ●○○○○ -0.43 -0.428785587133192
Streptococcus pyogenes M1 5448  SP5448_01655  WP_002992262.1  124 aa helix-turn-helix transcriptional regulator n.s. ●○○○○ -0.43 -0.4285481018567
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0699  WP_002868848.1  A0A0H3PAR9  kdpA  563 aa potassium-transporting ATPase subunit A n.s. ●○○○○ -0.43 -0.428477477545
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2225  CBW18327.1  A0A0H3NF50  napC  200 aa cytochrome c-type protein NapC n.s. ●○○○○ -0.43 -0.428416633932243
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