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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_07900  ATI05640.1  178 aa HD family hydrolase 7.3e-8 ●○○○○ -0.13 -0.133025645862057
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3190  AIK81758.1  338 aa chain length determinant family protein 1.7e-12 ●○○○○ -0.13 -0.132474998709326
Escherichia coli M12  CO715_14975  ATI06901.1  362 aa c-di-GMP phosphodiesterase 4.2e-22 ●○○○○ -0.13 -0.132191061805062
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1458  NP_231101.1  P38442  zot  399 aa zona occludens toxin 0.0093 ●○○○○ -0.13 -0.132186440291066
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2300  AIK80904.1  512 aa badF/BadG/BcrA/BcrD ATPase family protein <1e-323 ●○○○○ -0.13 -0.131862586040249
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2438  AIK81035.1  536 aa multicopper oxidase with role in copper homeostasis <1e-323 ●○○○○ -0.13 -0.131774455020635
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2539  AIK81136.1  283 aa citrate (pro-3S)-lyase, beta subunit 0.0037 ●○○○○ -0.13 -0.131207425185653
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1783  NP_231418.1  Q9KR60  378 aa N-acetylglucosamine-6-phosphate deacetylase 0.00068 ●○○○○ -0.13 -0.130736703280897
Escherichia coli M12  CO715_22635  ATI08277.1  229 aa DNA-binding response regulator 6.6e-11 ●○○○○ -0.13 -0.130104601662573
Escherichia coli M12  CO715_15415  ATI06979.1  329 aa sulfate-binding protein 3.3e-14 ●○○○○ -0.13 -0.129478663619826
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2784  AIK81373.1  43 aa hypothetical protein 0.014 ●○○○○ -0.13 -0.129322637532825
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1675  NP_231311.1  Q9KRG7  343 aa multidrug resistance protein 0.0019 ●○○○○ -0.13 -0.12926834762764
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2283  NP_231914.1  Q9KPS9  451 aa sodium-dependent transporter 0.0069 ●○○○○ -0.13 -0.128818334353803
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2714  AIK81304.1  419 aa flavin containing amine oxidoreductase family protein 1.2e-9 ●○○○○ -0.13 -0.128471889963193
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2829  AIK81418.1  99 aa hypothetical protein 0.0015 ●○○○○ -0.13 -0.128407647149589
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2774  AIK81363.1  436 aa bacterial extracellular solute-binding family protein <1e-323 ●○○○○ -0.13 -0.128355960379211
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1986  AIK80592.1  122 aa hypothetical protein 6.8e-5 ●○○○○ -0.13 -0.128260454016837
Escherichia coli M12  CO715_09645  ATI05947.1  475 aa J domain-containing protein 2.1e-59 ●○○○○ -0.13 -0.128226787534333
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2984  AIK81569.1  242 aa transcriptional regulatory, C terminal family protein <1e-323 ●○○○○ -0.13 -0.127721848575626
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2525  AIK81122.1  329 aa 4-hydroxythreonine-4-phosphate dehydrogenase 0.017 ●○○○○ -0.13 -0.127431779213196
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0657  NP_233046.1  Q9KLT4  512 aa glycerol-3-phosphate dehydrogenase 0.0014 ●○○○○ -0.13 -0.127050261044084
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2403  AIK81000.1  114 aa lipo, PulS/OutS family protein 9.7e-5 ●○○○○ -0.13 -0.126518840752752
Escherichia coli M12  CO715_11220  ATI06222.1  388 aa ABC transporter substrate-binding protein 6.3e-16 ●○○○○ -0.13 -0.126140327391845
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0159  NP_232559.1  Q9KN07  313 aa hypothetical protein 0.002 ●○○○○ -0.13 -0.125332293737861
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2686  AIK81280.1  323 aa branched-chain amino acid transport system / permease component family protein 6.0e-11 ●○○○○ -0.12 -0.12370133669142
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1814  NP_231448.1  Q9KR33  cry1  461 aa deoxyribodipyrimidine photolyase 0.0037 ●○○○○ -0.12 -0.123609547832358
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0067  NP_229726.1  Q9KVS2  597 aa aminopeptidase 0.0069 ●○○○○ -0.12 -0.123517188899114
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0892  NP_233277.1  Q9KL56  132 aa hypothetical protein 0.018 ●○○○○ -0.12 -0.123420254532153
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0062  NP_229721.1  Q9KVS7  thiE  440 aa thiamine-phosphate pyrophosphorylase 0.0099 ●○○○○ -0.12 -0.123379306636384
Porphyromonas gingivalis ATCC 33277  PGN_2011  WP_012458683.1  B2RMD4  680 aa tetratricopeptide repeat protein 6.9e-6 ●○○○○ -0.12 -0.123365345949663
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2645  AIK81239.1  391 aa putative D-serine deaminase (D-serine dehydratase) protein 2.7e-6 ●○○○○ -0.12 -0.123037568394385
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3999  AIK82546.1  537 aa permease for cytosine/purines, uracil, thiamine,allantoin family protein 5.6e-13 ●○○○○ -0.12 -0.122758732332286
Escherichia coli M12  CO715_13535  ATI08810.1  77 aa hypothetical protein 0.0028 ●○○○○ -0.12 -0.122593345149614
Escherichia coli M12  CO715_15035  ATI06912.1  239 aa hypothetical protein 8.4e-13 ●○○○○ -0.12 -0.12155011507837
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1996  AIK80602.1  414 aa mechanosensitive ion channel family protein 1.1e-11 ●○○○○ -0.12 -0.121319695359731
Escherichia coli M12  CO715_01145  ATI04461.1  622 aa low affinity potassium transport system protein kup 0.027 ●○○○○ -0.12 -0.121132823049872
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2085  AIK80690.1  264 aa traB family protein 0.0019 ●○○○○ -0.12 -0.121024960198609
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0144  NP_232544.1  Q9KN22  351 aa hypothetical protein 0.031 ●○○○○ -0.12 -0.120551960602412
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1512  NP_231153.1  Q9KRX1  202 aa formate dehydrogenase iron-sulfur subunit 0.0056 ●○○○○ -0.12 -0.120189691715132
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1365  NP_231009.1  Q9KS94  queE  245 aa 7-carboxy-7-deazaguanine synthase QueE 0.00034 ●○○○○ -0.12 -0.119876614372088
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2019  NP_231653.1  Q9KQH9  fabF  414 aa 3-oxoacyl-ACP synthase 0.0017 ●○○○○ -0.12 -0.119653299952581
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2443  AIK81040.1  264 aa S-adenosylmethionine decarboxylase proenzyme 5.0e-5 ●○○○○ -0.12 -0.119077237601348
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2736  AIK81326.1  173 aa hypothetical protein 2.1e-5 ●○○○○ -0.12 -0.118720191727879
Escherichia coli M12  CO715_07895  ATI05639.1  274 aa hypothetical protein 4.5e-33 ●○○○○ -0.12 -0.118629070878886
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2463  AIK81060.1  401 aa type II secretion system (T2SS), F family protein <1e-323 ●○○○○ -0.12 -0.118211195567071
Escherichia coli M12  CO715_17215  ATI07303.1  423 aa FAD-dependent oxidoreductase 2.7e-32 ●○○○○ -0.12 -0.118003132836139
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0055  NP_232456.1  Q9KNB0  322 aa hypothetical protein 0.0099 ●○○○○ -0.12 -0.117683046092472
Escherichia coli M12  CO715_04140  ATI05004.1  340 aa hydrolase 0.042 ●○○○○ -0.12 -0.117377194793393
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5064  AIK83590.1  153 aa oxidoreductase molybdopterin binding domain protein 0.0077 ●○○○○ -0.12 -0.117136337291197
Escherichia coli M12  CO715_21255  ATI08031.1  647 aa c-type cytochrome biogenesis protein CcmF 2.2e-28 ●○○○○ -0.12 -0.116751256750646
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1745  NP_231381.1  Q9KR97  488 aa succinate-semialdehyde dehydrogenase 7.9e-5 ●○○○○ -0.12 -0.116584233423433
Escherichia coli M12  CO715_23175  ATI08370.1  268 aa SgcQ protein 2.1e-11 ●○○○○ -0.12 -0.116333964722148
Escherichia coli CFT073  c2510  AAN80965.1  A0A0H2VAW1  117 aa Hypothetical protein 0.021 ●○○○○ -0.12 -0.116293482497535
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3954  AIK82502.1  166 aa hypothetical protein 4.0e-5 ●○○○○ -0.12 -0.11549365797735
Escherichia coli M12  CO715_24455  ATI08583.1  255 aa class II glutamine amidotransferase 0.00058 ●○○○○ -0.12 -0.115082088636655
Escherichia coli M12  CO715_18835  ATI07591.1  857 aa chaperone protein ClpB 7.8e-16 ●○○○○ -0.11 -0.114873442622406
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0333  NP_229987.1  Q9KV25  242 aa TetR family transcriptional regulator 0.00017 ●○○○○ -0.11 -0.114728113991279
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4436  AIK82979.1  305 aa periplasmic solute binding family protein 3.6e-5 ●○○○○ -0.11 -0.114587284199955
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4605  AIK83139.1  308 aa mucB/RseB family protein 0.00023 ●○○○○ -0.11 -0.1141998727986
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1101  NP_230746.1  Q9KT04  321 aa hypothetical protein 5.4e-6 ●○○○○ -0.11 -0.113959444885994
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2190  AIK80795.1  179 aa hypothetical protein 3.1e-5 ●○○○○ -0.11 -0.113908789991548
Escherichia coli M12  CO715_13050  ATI06553.1  284 aa RNase adaptor protein RapZ 2.2e-27 ●○○○○ -0.11 -0.112786982479918
Escherichia coli M12  CO715_16875  ATI07241.1  361 aa murein transglycosylase B 2.0e-9 ●○○○○ -0.11 -0.112578336465669
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2513  AIK81110.1  500 aa L-arabinose isomerase 4.3e-7 ●○○○○ -0.11 -0.112249779423253
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2081  AIK80686.1  305 aa SPFH domain / Band 7 family protein 1.1e-16 ●○○○○ -0.11 -0.112229801099386
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0329  NP_232725.1  Q9K315  83 aa hypothetical protein 0.0012 ●○○○○ -0.11 -0.112164249584427
Escherichia coli M12  CO715_13500  ATI06631.1  99 aa hypothetical protein 1.1e-54 ●○○○○ -0.11 -0.111743752408673
Escherichia coli M12  CO715_13365  ATI06610.1  385 aa MexX family efflux pump subunit 6.7e-35 ●○○○○ -0.11 -0.111743752408673
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3328  AIK81885.1  207 aa 16S rRNA (guanine(527)-N(7))-methyltransferase GidB 7.6e-7 ●○○○○ -0.11 -0.111140505477702
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2563  AIK81160.1  174 aa GPR1/FUN34/yaaH family protein 2.3e-7 ●○○○○ -0.11 -0.109920597599873
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0172  NP_232572.1  Q9KMZ4  318 aa hypothetical protein 3.1e-6 ●○○○○ -0.11 -0.109598467371775
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0823  NP_230471.1  Q9KTR7  312 aa hypothetical protein 0.022 ●○○○○ -0.11 -0.108864539235742
Escherichia coli M12  CO715_00775  ATI04396.1  149 aa hypothetical protein 0.039 ●○○○○ -0.11 -0.10861406219494
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0489  NP_230143.1  Q9KUM6  586 aa hemolysin 1.8e-8 ●○○○○ -0.11 -0.108556915528554
Porphyromonas gingivalis ATCC 33277  PGN_0774  WP_012457769.1  B2RIU8  445 aa PAS domain-containing sensor histidine kinase 8.6e-7 ●○○○○ -0.11 -0.107628269115258
Porphyromonas gingivalis ATCC 33277  PGN_0097  WP_012457239.1  B2RGX1  246 aa ATP-binding cassette domain-containing protein 0.0039 ●○○○○ -0.11 -0.107628269115258
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4371  AIK82914.1  473 aa sugar (and other) transporter family protein <1e-323 ●○○○○ -0.11 -0.107239198151579
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0304  NP_229959.1  Q9KV53  gppA  497 aa guanosine pentaphosphate phosphohydrolase 0.00018 ●○○○○ -0.11 -0.106945133808581
Porphyromonas gingivalis ATCC 33277  PGN_1767  WP_039416503.1  B2RLP1  405 aa T9SS type A sorting domain-containing protein <1e-323 ●○○○○ -0.11 -0.106781591199644
Escherichia coli M12  CO715_08905  ATI05823.1  161 aa cyclic pyranopterin monophosphate synthase MoaC 0.028 ●○○○○ -0.11 -0.106527602052452
Escherichia coli M12  CO715_20820  ATI07951.1  194 aa 30S ribosomal protein S5 alanine N-acetyltransferase 4.5e-10 ●○○○○ -0.11 -0.106318956038203
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1334  NP_230978.1  Q9KSC4  323 aa hypothetical protein 0.019 ●○○○○ -0.11 -0.10564156930136
Escherichia coli M12  CO715_17225  ATI07305.1  191 aa glycerol uptake operon antiterminator 0.0065 ●○○○○ -0.11 -0.105484371981207
Escherichia coli M12  CO715_14210  ATI06758.1  844 aa penicillin-binding protein 1B 0.00039 ●○○○○ -0.11 -0.10506707995271
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4443  AIK82986.1  445 aa lamB porin family protein <1e-323 ●○○○○ -0.1 -0.104365458087757
Escherichia coli M12  CO715_14205  ATI06757.1  752 aa ferrichrome porin FhuA 1.2e-18 ●○○○○ -0.1 -0.104232495895714
Escherichia coli M12  CO715_04750  ATI05106.1  552 aa flagellar M-ring protein FliF 0.014 ●○○○○ -0.1 -0.104023849881465
Escherichia coli M12  CO715_08225  ATI05700.1  476 aa amino acid permease 5.4e-75 ●○○○○ -0.1 -0.103606557852968
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0996  NP_233380.1  Q9KKV4  619 aa ABC transporter ATP-binding protein 0.0012 ●○○○○ -0.1 -0.10284763001059
Escherichia coli M12  CO715_09865  ATI05987.1  300 aa LysR family transcriptional regulator 3.1e-79 ●○○○○ -0.1 -0.102563327781723
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0042  NP_232443.1  Q9KNC3  252 aa hypothetical protein 0.03 ●○○○○ -0.1 -0.102173404528375
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2993  AIK81578.1  365 aa fimbrial family protein <1e-323 ●○○○○ -0.1 -0.101760512605911
Escherichia coli CFT073  c1047  AAN79517.1  A0A0H2V5T1  ycaL  257 aa Putative metalloprotease ycaL 0.04 ●○○○○ -0.1 -0.101481621762338
Escherichia coli M12  CO715_05935  ATI05299.1  346 aa peptidase S74 5.0e-20 ●○○○○ -0.1 -0.100685513653484
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2710  AIK81300.1  177 aa blc outer membrane lipoprotein 0.00073 ●○○○○ -0.1 -0.100278746579926
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2239  AIK80844.1  382 aa penicillin-binding protein <1e-323 ●○○○○ -0.1 -0.100112835772286
Escherichia coli M12  CO715_11035  ATI06187.1  632 aa hypothetical protein 3.0e-148 ●○○○○ -0.1 -0.0998509295964882
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0052  NP_232453.2  Q9KNB3  489 aa hypothetical protein 0.00044 ●○○○○ -0.1 -0.0996781542713203
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1901  NP_231535.1  Q9KQU7  nhaB  530 aa sodium/proton antiporter 0.012 ●○○○○ -0.1 -0.0995273186897331
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2823  AIK81412.1  384 aa lactonase, 7-bladed beta-propeller family protein <1e-323 ●○○○○ -0.1 -0.0993836772360958
Retrieved entries 6,701–6,800 out of 36,363 total in 7.6 ms (Link to these results)