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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Serratia marcescens Strain UMH9  BVG96_09830  ASL97898.1  301 aa 23S rRNA pseudouridylate synthase B n.s. ●●○○○ -1.53 -1.52800915535214
Serratia marcescens Strain UMH9  BVG96_18220  ASL99441.1  170 aa transcriptional regulator Zur n.s. ●●○○○ -1.53 -1.5277887963197
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1044  AIK79667.1  327 aa quinone oxidoreductase domain protein n.s. ●●○○○ -1.53 -1.52643094291477
Vibrio parahaemolyticus RIMD 2210633  VP_2495  BAC60758.1  Q87LW3  865 aa aconitate hydratase 2 n.s. ●●○○○ -1.53 -1.52611030074045
Streptococcus pyogenes M1 5448  SP5448_04185  WP_010922396.1  364 aa DUF871 domain-containing protein n.s. ●●○○○ -1.53 -1.52581758074786
Escherichia coli CFT073  c1171  AAN79639.1  A0A0H2V824  197 aa Conserved hypothetical protein n.s. ●●○○○ -1.53 -1.52558523097165
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4458  CBW20547.1  A0A0H3NWC4  mrr  304 aa Mrr restriction system protein n.s. ●●○○○ -1.52 -1.52316725167554
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0313  CBW16414.1  A0A0H3N800  gpt  152 aa xanthine-guanine phosphoribosyltransferase n.s. ●●○○○ -1.52 -1.52238990313742
Streptococcus pyogenes M1 5448  SP5448_06690  WP_002985256.1  166 aa queuosine transporter QueT n.s. ●●○○○ -1.52 -1.5219722347556
Escherichia coli O157:H7 str. EDL933  Z4535  AAG58308.1  547 aa putative alkaline phosphatase I n.s. ●●○○○ -1.52 -1.52177539916831
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2879  CBW18977.1  E1WAE4  invH  147 aa outer membrane lipoprotein n.s. ●●○○○ -1.52 -1.52109606304606
Serratia marcescens Strain UMH9  BVG96_21530  ASM00041.1  256 aa ABC transporter ATP-binding protein n.s. ●●○○○ -1.52 -1.51992928764996
Vibrio parahaemolyticus RIMD 2210633  VP_2045  BAC60308.1  Q87N30  39 aa hypothetical protein n.s. ●●○○○ -1.52 -1.51956605372413
Escherichia coli CFT073  c2201  AAN80660.1  A0A0H2V980  40 aa Hypothetical protein n.s. ●●○○○ -1.52 -1.5192971083492
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0298  CBW16399.1  A0A0H3ND88  safD  156 aa fimbrial structural subunit n.s. ●●○○○ -1.52 -1.51834254306209
Escherichia coli O157:H7 str. EDL933  Z0007  AAG54307.1  476 aa inner membrane transport protein n.s. ●●○○○ -1.52 -1.51752821531137
Streptococcus pyogenes M1 5448  SP5448_03330  WP_002983862.1  439 aa cell division protein FtsZ n.s. ●●○○○ -1.52 -1.51716555226528
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0937  WP_002869161.1  A0A0H3P9I9  ychF  367 aa redox-regulated ATPase YchF n.s. ●●○○○ -1.52 -1.51715799586
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0506  CBW16606.1  A0A0H3NA64  ybbB  364 aa hypothetical ATP-binding protein n.s. ●●○○○ -1.52 -1.51643152560495
Streptococcus pyogenes M1 5448  SP5448_05415  WP_002984720.1  243 aa acid phosphatase AphA n.s. ●●○○○ -1.52 -1.51524287926915
Streptococcus pyogenes M1 5448  SP5448_04220  WP_002984187.1  246 aa amino acid ABC transporter ATP-binding protein n.s. ●●○○○ -1.52 -1.51524287926915
Escherichia coli O157:H7 str. EDL933  Z5160  AAG58869.1  367 aa hypothetical protein n.s. ●●○○○ -1.52 -1.51523032627207
Escherichia coli CFT073  c2578  AAN81033.1  A0A0H2V8M4  wcaG  321 aa GDP-fucose synthetase n.s. ●●○○○ -1.51 -1.51429442468127
Escherichia coli CFT073  c1666  AAN80131.1  Q8FI04  ispE  283 aa 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase n.s. ●●○○○ -1.51 -1.51429442468127
Escherichia coli CFT073  c2573  AAN81028.1  A0A0H2V8L9  cpsG  472 aa Phosphomannomutase n.s. ●●○○○ -1.51 -1.5137433282745
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4133  CBW20221.1  A0A0H3NID1  151 aa hypothetical protein n.s. ●●○○○ -1.51 -1.51341440781483
Escherichia coli O157:H7 str. EDL933  Z0002  AAG54302.1  820 aa aspartokinase I, homoserine dehydrogenase I n.s. ●●○○○ -1.51 -1.51224646030144
Vibrio parahaemolyticus RIMD 2210633  VP_0141  BAC58404.1  Q87TC9  404 aa general secretion pathway protein L n.s. ●●○○○ -1.51 -1.51201716145223
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1053  WP_002852998.1  A0A0H3PAH2  268 aa adenylosuccinate lyase n.s. ●●○○○ -1.51 -1.51171135417
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0728  WP_002854814.1  A0A0H3P9L3  241 aa Nif3-like dinuclear metal center hexameric protein n.s. ●●○○○ -1.51 -1.51096197979
Escherichia coli O157:H7 str. EDL933  Z4888  AAG58622.1  557 aa hypothetical protein n.s. ●●○○○ -1.51 -1.5108757068398
Streptococcus pyogenes M1 5448  SP5448_07280  WP_002985621.1  69 aa helix-turn-helix domain-containing protein n.s. ●●○○○ -1.51 -1.51043619677883
Serratia marcescens Strain UMH9  BVG96_05305  ASL97062.1  257 aa hypothetical protein n.s. ●●○○○ -1.51 -1.51026925756956
Serratia marcescens Strain UMH9  BVG96_10570  ASL98035.1  460 aa ATP-dependent RNA helicase DbpA n.s. ●●○○○ -1.51 -1.50902119370786
Streptococcus pyogenes M1 5448  SP5448_02210  WP_002988670.1  183 aa hypothetical protein n.s. ●●○○○ -1.51 -1.5085135237827
Escherichia coli CFT073  c2575  AAN81030.1  A0A0H2VB05  cpsB  478 aa Mannose-1-phosphate guanylyltransferase n.s. ●●○○○ -1.51 -1.50843214233074
Escherichia coli O157:H7 str. EDL933  Z3184  AAG57081.1  356 aa imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase n.s. ●●○○○ -1.51 -1.50685279209792
Streptococcus pyogenes M1 5448  SP5448_03920  WP_010922425.1  601 aa oligoendopeptidase F n.s. ●●○○○ -1.51 -1.50659085078657
Streptococcus pyogenes M1 5448  SP5448_07730  WP_010921950.1  204 aa hypothetical protein n.s. ●●○○○ -1.51 -1.50659085078657
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3301  AIK81862.1  930 aa DNA polymerase I, 3' -- 5' polymerase, 5' -- 3' and 3' -- 5' exonuclease n.s. ●●○○○ -1.51 -1.50570303873531
Escherichia coli CFT073  c2812  AAN81266.1  Q8FFK8  rbn  305 aa Protein elaC n.s. ●●○○○ -1.5 -1.50386205264615
Escherichia coli CFT073  c2856  AAN81308.1  A0A0H2V934  purF  505 aa Amidophosphoribosyltransferase n.s. ●●○○○ -1.5 -1.50376772668337
Haemophilus influenzae Rd KW20  HI_0164  NP_438334.1  P43955  nqrA  447 aa Na(+)-translocating NADH-quinone reductase subunit A n.s. ●●○○○ -1.5 -1.50347007562491
Escherichia coli CFT073  c0855  AAN79328.1  Q8FJQ3  bioB  346 aa Biotin synthase n.s. ●●○○○ -1.5 -1.50340453496489
Escherichia coli CFT073  c5331  AAN83752.1  A0A0H2VE28  yjfG  457 aa UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase n.s. ●●○○○ -1.5 -1.50340453496489
Vibrio parahaemolyticus RIMD 2210633  VP_2550  BAC60813.1  Q87LR1  recA  347 aa RecA protein n.s. ●●○○○ -1.5 -1.50308004370979
Escherichia coli CFT073  c2141  AAN80600.1  Q8FH05  ves  212 aa Hypothetical protein ydjR n.s. ●●○○○ -1.5 -1.5011303312002
Streptococcus pyogenes M1 5448  SP5448_00255  WP_010921778.1  369 aa 5-(carboxyamino)imidazole ribonucleotide synthase n.s. ●●○○○ -1.5 -1.50082283179818
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2572  CBW18673.1  A0A0H3NPZ8  643 aa predicted bacteriophage protein n.s. ●●○○○ -1.5 -1.50075499089698
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0103  CBW16206.1  A0A0H3NH62  araB  569 aa Ribulokinase n.s. ●●○○○ -1.5 -1.50072287104734
Escherichia coli O157:H7 str. EDL933  Z0376  AAG54633.1  296 aa putative AraC-like transcriptional regulator n.s. ●●○○○ -1.5 -1.49999262617557
Haemophilus influenzae Rd KW20  HI_0427  NP_438588.2  P44706  nhaB  514 aa sodium/proton antiporter n.s. ●●○○○ -1.5 -1.49991076950785
Streptococcus pyogenes M1 5448  SP5448_08820  WP_010922721.1  271 aa streptodornase B n.s. ●●○○○ -1.5 -1.49986149530011
Streptococcus pyogenes M1 5448  SP5448_01500  WP_002988147.1  191 aa DNA-directed RNA polymerase subunit delta n.s. ●●○○○ -1.5 -1.49986149530011
Escherichia coli O157:H7 str. EDL933  Z4184  AAG57976.1  166 aa hypothetical protein n.s. ●●○○○ -1.5 -1.49966356156266
Escherichia coli CFT073  c0600  AAN79078.1  A0A0H2V4Z8  ushA  550 aa Protein ushA precursor n.s. ●●○○○ -1.5 -1.4996387126413
Streptococcus pyogenes M1 5448  SP5448_03565  WP_002988359.1  109 aa hypothetical protein n.s. ●●○○○ -1.5 -1.49793882230398
Streptococcus pyogenes M1 5448  SP5448_02280  WP_002988715.1  132 aa hypothetical protein n.s. ●●○○○ -1.5 -1.49793882230398
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1127  WP_002826100.1  A1W096  aat  215 aa leucyl/phenylalanyl-tRNA--protein transferase n.s. ●●○○○ -1.5 -1.49788018141
Escherichia coli CFT073  c1412  AAN79881.1  A0A0H2V8H6  331 aa Hypothetical protein n.s. ●●○○○ -1.5 -1.49764496872823
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4031  CBW20120.1  A0A0H3NNU1  yiiQ  198 aa conserved hypothetical protein n.s. ●●○○○ -1.5 -1.49705393440712
Vibrio parahaemolyticus RIMD 2210633  VPA_1102  BAC62445.1  Q87H63  58 aa hypothetical protein n.s. ●●○○○ -1.5 -1.49704498044707
Escherichia coli CFT073  c2016  AAN80476.1  A0A0H2V7I3  ydgJ  359 aa Hypothetical oxidoreductase ydgJ n.s. ●●○○○ -1.5 -1.49618328535869
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0376  WP_002868919.1  A0A0H3PEG3  265 aa hypothetical protein n.s. ●●○○○ -1.5 -1.49595266831
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2104  CBW18200.1  A0A0H3NDE6  yegN  1040 aa hypothetical RND-family transporter protein n.s. ●●○○○ -1.5 -1.49588155865897
Escherichia coli O157:H7 str. EDL933  Z0887  AAG55057.1  550 aa putative fumarate hydratase n.s. ●●○○○ -1.5 -1.49580708051547
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2668  CBW18770.1  A0A0H3NQA5  935 aa predicted bacteriophage protein n.s. ●●○○○ -1.5 -1.49573173806201
Streptococcus pyogenes M1 5448  SP5448_04320  WP_010922383.1  453 aa sugar ABC transporter permease n.s. ●●○○○ -1.49 -1.49313213981366
Escherichia coli CFT073  c2305  AAN80764.1  A0A0H2V815  motA  295 aa Chemotaxis motA protein n.s. ●●○○○ -1.49 -1.49297090588547
Escherichia coli CFT073  c1982  AAN80442.1  Q8CW16  dmsD  207 aa Hypothetical protein ynfI precursor n.s. ●●○○○ -1.49 -1.49223201146042
Streptococcus pyogenes M1 5448  SP5448_04845  WP_010922358.1  295 aa phosphate ABC transporter permease PstA n.s. ●●○○○ -1.49 -1.4921708033156
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1039  WP_002853959.1  A0A0H3PAJ2  144 aa c-type cytochrome n.s. ●●○○○ -1.49 -1.49175449237
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0018  CBW16119.2  A0A0H3N7I6  chiA  627 aa chitinase n.s. ●●○○○ -1.49 -1.49150994934919
Streptococcus pyogenes M1 5448  SP5448_02220  WP_011285676.1  133 aa helix-turn-helix transcriptional regulator n.s. ●●○○○ -1.49 -1.49024813031947
Escherichia coli CFT073  c1623  AAN80088.1  Q8FI31  minC  236 aa Septum site-determining protein minC n.s. ●●○○○ -1.49 -1.49003387046534
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1510  WP_002855371.1  A0A0H3PAG4  148 aa molybdenum cofactor biosynthesis protein MoaE n.s. ●●○○○ -1.49 -1.4895790847
Streptococcus pyogenes M1 5448  SP5448_08650  WP_011285736.1  88 aa hypothetical protein n.s. ●●○○○ -1.49 -1.4892867938214
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3434  CBW19529.1  A0A0H3NGU6  yhfK  695 aa conserved membrane protein n.s. ●●○○○ -1.49 -1.48926561766651
Escherichia coli CFT073  c2347  AAN80806.1  A0A0H2V9I7  48 aa Hypothetical protein n.s. ●●○○○ -1.49 -1.48890797269595
Escherichia coli O157:H7 str. EDL933  Z5935  AAG59518.1  731 aa hypothetical protein n.s. ●●○○○ -1.49 -1.4887107717434
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2154  AIK80759.1  194 aa ATP-dependent Clp endopeptidase, proteolytic subunit ClpP n.s. ●●○○○ -1.49 -1.48790938443949
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0432  WP_002854660.1  A0A0H3PEJ9  frdC  260 aa fumarate reductase cytochrome b subunit n.s. ●●○○○ -1.49 -1.48735234532
Escherichia coli O157:H7 str. EDL933  Z5774  AAG59363.1  515 aa orf, hypothetical protein n.s. ●●○○○ -1.49 -1.48704139857092
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3953  CBW20043.1  A0A0H3NI04  glnL  349 aa Two-component system sensory histidine kinase n.s. ●●○○○ -1.49 -1.48674616456709
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4179  CBW20266.1  A0A0H3NIF5  yjbN  332 aa conserved hypothetical protein n.s. ●●○○○ -1.49 -1.48670226506998
Streptococcus pyogenes M1 5448  SP5448_07255  WP_011285435.1  101 aa type II toxin-antitoxin system RelE/ParE family toxin n.s. ●●○○○ -1.49 -1.48640278432721
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1475  WP_002856630.1  A0A0H3PDK8  788 aa hypothetical protein n.s. ●●○○○ -1.49 -1.48625312221
Serratia marcescens Strain UMH9  BVG96_05800  ASL97157.1  218 aa DNA-binding response regulator n.s. ●●○○○ -1.49 -1.48589247798788
Vibrio parahaemolyticus RIMD 2210633  VP_0100  BAC58363.1  Q87TG9  tatC  246 aa conserved hypothetical protein n.s. ●●○○○ -1.49 -1.48559979371405
Escherichia coli CFT073  c1099  AAN79567.1  A0A0H2V5V8  helD  715 aa Helicase IV n.s. ●●○○○ -1.48 -1.48451754267204
Vibrio parahaemolyticus RIMD 2210633  VP_2475  BAC60738.1  Q87LY3  hemL  431 aa glutamate-1-semialdehyde 2,1-aminomutase n.s. ●●○○○ -1.48 -1.48441562740476
Escherichia coli CFT073  c2644  AAN81100.1  A0A0H2V8V2  yehI  1210 aa Hypothetical protein yehI n.s. ●●○○○ -1.48 -1.48419696552716
Serratia marcescens Strain UMH9  BVG96_10160  ASM00515.1  338 aa L-asparaginase 1 n.s. ●●○○○ -1.48 -1.4836541874183
Streptococcus pyogenes M1 5448  SP5448_04545  WP_009880259.1  114 aa hypothetical protein n.s. ●●○○○ -1.48 -1.48351877483301
Escherichia coli O157:H7 str. EDL933  Z2554  AAG56558.1  166 aa putative structural proteins n.s. ●●○○○ -1.48 -1.48255642504037
Serratia marcescens Strain UMH9  BVG96_17765  ASL99356.1  328 aa D-arabinose 5-phosphate isomerase n.s. ●●○○○ -1.48 -1.48248756042202
Escherichia coli CFT073  c1426  AAN79895.1  A0A0H2V6I5  273 aa Antitermination protein Q homolog of cryptic prophage n.s. ●●○○○ -1.48 -1.48200016173099
Escherichia coli CFT073  c3236  AAN81688.1  A0A0H2V9T8  ygaH  111 aa Hypothetical protein ygaH n.s. ●●○○○ -1.48 -1.48194853558841
Escherichia coli CFT073  c1390  AAN79859.1  A0A0H2V6A6  ycfT  357 aa Hypothetical protein ycfT n.s. ●●○○○ -1.48 -1.48103897567602
Escherichia coli CFT073  c1069  AAN79537.1  A0A0H2V5U1  ycbL  215 aa Hypothetical protein ycbL n.s. ●●○○○ -1.48 -1.48087194004425
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