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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Streptococcus pyogenes M1 5448  SP5448_02155  WP_009880751.1  153 aa tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE n.s. ●●○○○ -1.39 -1.39026913452073
Escherichia coli CFT073  c2396  AAN80855.1  A0A0H2V8G6  104 aa Hypothetical protein n.s. ●●○○○ -1.39 -1.3898692714583
Haemophilus influenzae Rd KW20  HI_0756  NP_438915.1  P44864  410 aa hypothetical protein n.s. ●●○○○ -1.39 -1.38935502742168
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1002  CBW17098.1  A0A0H3NAD4  uup  635 aa ABC transporter ATP-binding protein n.s. ●●○○○ -1.39 -1.38935108683014
Serratia marcescens Strain UMH9  BVG96_18245  ASL99446.1  821 aa glycerol-3-phosphate 1-O-acyltransferase n.s. ●●○○○ -1.39 -1.38888727083288
Vibrio parahaemolyticus RIMD 2210633  VPA_0900  BAC62243.1  Q877Q6  103 aa hypothetical protein n.s. ●●○○○ -1.39 -1.38846955741835
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3701  CBW19795.1  A0A0H3NHH1  yicC  287 aa conserved hypothetical protein n.s. ●●○○○ -1.39 -1.38830381519432
Escherichia coli CFT073  c2270  AAN80727.1  P0AFT0  mepM  440 aa Hypothetical protein yebA precursor n.s. ●●○○○ -1.39 -1.38787510288613
Escherichia coli M12  CO715_21015  ATI07990.1  119 aa histidine triad nucleotide-binding protein n.s. ●●○○○ -1.39 -1.38782277555471
Vibrio parahaemolyticus RIMD 2210633  VPA_0685  BAC62028.1  Q87IC1  327 aa MoxR-related protein n.s. ●●○○○ -1.39 -1.38747052398278
Streptococcus pyogenes M1 5448  SP5448_09105  WP_010922753.1  378 aa recombinase RecA n.s. ●●○○○ -1.39 -1.38642378852847
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2062  CBW18158.1  A0A0H3ND22  rfbN  314 aa rhamnosyltransferase n.s. ●●○○○ -1.39 -1.38633638857
Serratia marcescens Strain UMH9  BVG96_22815  ASM00266.1  141 aa ribonuclease E inhibitor RraB n.s. ●●○○○ -1.39 -1.38526705128353
Escherichia coli CFT073  c2482  AAN80941.1  A0A0H2V8J2  715 aa Putative outer membrane receptor for iron compound or colicin n.s. ●●○○○ -1.38 -1.38490912692851
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3912  CBW20003.1  A0A0H3NHW7  recQ  615 aa ATP-dependent DNA helicase n.s. ●●○○○ -1.38 -1.38490322099589
Escherichia coli O157:H7 str. EDL933  Z5905  AAG59491.1  326 aa orf, hypothetical protein n.s. ●●○○○ -1.38 -1.38474609179452
Mycobacterium avium subsp. paratuberculosis K10  MAP_0324  AAS02641.1  Q744L7  277 aa hypothetical protein n.s. ●●○○○ -1.38 -1.38414570548052
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3236  CBW19332.1  A0A0H3NGA5  yraL  287 aa conserved hypothetical protein n.s. ●●○○○ -1.38 -1.38300386625558
Vibrio parahaemolyticus RIMD 2210633  VPA_0861  BAC62204.1  Q87HU5  262 aa conserved hypothetical protein n.s. ●●○○○ -1.38 -1.38220661091879
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0726  WP_002852251.1  A0A0H3PHJ5  178 aa DUF3972 domain-containing protein n.s. ●●○○○ -1.38 -1.38080659869
Escherichia coli O157:H7 str. EDL933  Z5279  AAG58963.1  548 aa acetohydroxy acid synthase II n.s. ●●○○○ -1.38 -1.38061006775367
Escherichia coli O157:H7 str. EDL933  Z4166  AAG57958.1  230 aa orf, hypothetical protein n.s. ●●○○○ -1.38 -1.38060832362261
Vibrio parahaemolyticus RIMD 2210633  VP_0647  BAC58910.1  Q87RX9  bamE  119 aa small protein A n.s. ●●○○○ -1.38 -1.37955111284575
Escherichia coli CFT073  c3121  AAN81571.1  A0A0H2V9K7  tyrA  373 aa T-protein n.s. ●●○○○ -1.38 -1.37952257641402
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3819  CBW19910.1  A0A0H3NN90  yieH  221 aa hypothetical hydrolase n.s. ●●○○○ -1.38 -1.37947249956723
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0357  WP_011812703.1  A0A0H3PAJ9  flhB  368 aa flagellar biosynthesis protein FlhB n.s. ●●○○○ -1.38 -1.37929189837
Escherichia coli CFT073  c2217  AAN80676.1  A0A0H2V992  pabB  453 aa Para-aminobenzoate synthase component I n.s. ●●○○○ -1.38 -1.37892278115097
Mycobacterium avium subsp. paratuberculosis K10  MAP_2829  AAS05146.1  Q73W31  471 aa hypothetical protein n.s. ●●○○○ -1.38 -1.37877573775919
Streptococcus pyogenes M1 5448  SP5448_03940  WP_010922424.1  872 aa alanine--tRNA ligase n.s. ●●○○○ -1.38 -1.37873309654395
Escherichia coli CFT073  c2158  AAN80617.1  A0A0H2V7T0  440 aa Putative thiosulfate sulfurtransferase ynjE precursor n.s. ●●○○○ -1.38 -1.37796204562657
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1493  WP_002851188.1  A0A0H3P9W6  75 aa putative sulfurtransferase YedF n.s. ●●○○○ -1.38 -1.37740574788
Escherichia coli CFT073  c0980  AAN79453.1  P60870  ybjL  561 aa Hypothetical membrane protein ybjL n.s. ●●○○○ -1.38 -1.37721326043074
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2909  CBW19008.1  A0A0H3NH37  ispD  236 aa 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase n.s. ●●○○○ -1.38 -1.37708600524033
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0164  CBW16266.1  A0A0H3N967  pdxAb  327 aa 4-hydroxythreonine-4-phosphate dehydrogenase n.s. ●●○○○ -1.38 -1.37670650234442
Vibrio parahaemolyticus RIMD 2210633  VPA_1276  BAC62619.1  Q87GN9  237 aa putative DNA-binding response regulator n.s. ●●○○○ -1.38 -1.3755681476091
Streptococcus pyogenes M1 5448  SP5448_07665  WP_002990814.1  284 aa metal ABC transporter permease n.s. ●●○○○ -1.37 -1.37488775055169
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1025  CBW17121.1  A0A0H3NA12  yccA  192 aa hypothetical membrane protein n.s. ●●○○○ -1.37 -1.37480872557676
Escherichia coli CFT073  c1130  AAN79598.1  A0A0H2V802  torT  342 aa Periplasmic protein torT precursor n.s. ●●○○○ -1.37 -1.37472934134236
Escherichia coli CFT073  c1693  AAN80160.1  A0A0H2V984  204 aa Hypothetical protein n.s. ●●○○○ -1.37 -1.37467070410156
Mycobacterium avium subsp. paratuberculosis K10  MAP_0206  AAS02523.1  Q745K1  259 aa hypothetical protein n.s. ●●○○○ -1.37 -1.37344246417038
Serratia marcescens Strain UMH9  BVG96_06400  ASL97265.1  306 aa rhizopine-binding protein n.s. ●●○○○ -1.37 -1.37318598720427
Mycobacterium avium subsp. paratuberculosis K10  MAP_2200  AAS04517.1  Q73XV8  527 aa hypothetical protein n.s. ●●○○○ -1.37 -1.37297022424046
Escherichia coli CFT073  c2121  AAN80580.1  A0A0H2V7Q1  pfkB  310 aa 6-phosphofructokinase isozyme 2 n.s. ●●○○○ -1.37 -1.37260276870132
Escherichia coli CFT073  c0919  AAN79392.1  A0A0H2V5K5  yliF  442 aa Hypothetical membrane protein yliF n.s. ●●○○○ -1.37 -1.37222539396905
Escherichia coli O157:H7 str. EDL933  Z2702  AAG56661.1  208 aa putative oxidoreductase, Fe-S subunit n.s. ●●○○○ -1.37 -1.37214807658547
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1607  WP_000960833.1  E8XJ42  srfB  993 aa virulence factor SrfB n.s. ●●○○○ -1.37 -1.37209818034599
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0856  CBW16952.1  A0A0H3NET5  potH  317 aa putrescine transport system permease protein PotH n.s. ●●○○○ -1.37 -1.37177905095944
Escherichia coli CFT073  c1784  AAN80250.1  A0A0H2V716  ycjP  280 aa Hypothetical ABC transporter permease protein ycjP n.s. ●●○○○ -1.37 -1.37142603939648
Escherichia coli M12  CO715_09150  ATI05862.1  421 aa cell envelope integrity protein TolA n.s. ●●○○○ -1.37 -1.3711310944148
Escherichia coli CFT073  c2171  AAN80630.1  A0A0H2VA41  ansA  338 aa L-asparaginase I n.s. ●●○○○ -1.37 -1.37078392870061
Escherichia coli O157:H7 str. EDL933  Z1881  AAG55978.1  64 aa unknown protein encoded by prophage CP-933X n.s. ●●○○○ -1.37 -1.37041885733103
Vibrio parahaemolyticus RIMD 2210633  VPA_0640  BAC61983.1  Q87IG6  190 aa putative protocatechuate 3,4-dioxygenase beta chain protein n.s. ●●○○○ -1.37 -1.37035008151251
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1035  WP_002869431.1  A0A0H3PCW1  livM  350 aa branched-chain amino acid ABC transporter permease n.s. ●●○○○ -1.37 -1.37017190069
Serratia marcescens Strain UMH9  BVG96_03695  ASL96756.1  232 aa urea ABC transporter ATP-binding subunit UrtE n.s. ●●○○○ -1.37 -1.36956335613638
Escherichia coli M12  CO715_17120  ATI07286.1  107 aa hypothetical protein n.s. ●●○○○ -1.37 -1.36925328028656
Escherichia coli CFT073  c1731  AAN80197.1  A0A0H2V710  trpH  293 aa Protein trpH n.s. ●●○○○ -1.37 -1.36915199909073
Mycobacterium avium subsp. paratuberculosis K10  MAP_0732c  AAS03049.1  Q742V3  328 aa hypothetical protein n.s. ●●○○○ -1.37 -1.36859754562314
Mycobacterium avium subsp. paratuberculosis K10  MAP_0712c  AAS03029.1  Q742X3  216 aa hypothetical protein n.s. ●●○○○ -1.37 -1.36821967843724
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3485  CBW19580.1  A0A0H3NMM8  rtcA  339 aa rna 3'-terminal phosphate cyclase (ec 6.5.1.4) (rna-3'-phosphate cyclase) (rna cyclase) n.s. ●●○○○ -1.37 -1.368168828153
Escherichia coli CFT073  c3342  AAN81790.1  A0A0H2VA36  ygcG  294 aa Hypothetical protein ygcG n.s. ●●○○○ -1.37 -1.36769197503881
Mycobacterium avium subsp. paratuberculosis K10  MAP_2656  AAS04973.1  Q73WK4  366 aa hypothetical protein n.s. ●●○○○ -1.37 -1.36698058756854
Mycobacterium avium subsp. paratuberculosis K10  MAP_1531c  AAS03848.1  Q73ZS0  639 aa hypothetical protein n.s. ●●○○○ -1.37 -1.36682270794398
Haemophilus influenzae Rd KW20  HI_0888  NP_439049.1  P43845  purD  429 aa phosphoribosylamine--glycine ligase n.s. ●●○○○ -1.37 -1.36612218443438
Escherichia coli CFT073  c2597  AAN81053.1  A0A0H2V8X4  yegI  649 aa Hypothetical protein yegI n.s. ●●○○○ -1.37 -1.36606727592919
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3991  CBW20080.1  A0A0H3NI53  188 aa hypothetical DNA-binding protein n.s. ●●○○○ -1.37 -1.36594153449501
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3285  CBW19381.1  A0A0H3NGF2  yrbF  270 aa possible ABC-transport protein, ATP-binding component n.s. ●●○○○ -1.37 -1.36582160140818
Escherichia coli CFT073  c2338  AAN80797.1  A0A0H2VAE3  fliC  595 aa Flagellin n.s. ●●○○○ -1.37 -1.36565360055209
Escherichia coli CFT073  c0984  AAN79457.1  A0A0H2V6G7  mdaA  240 aa Oxygen-insensitive NADPH nitroreductase n.s. ●●○○○ -1.37 -1.36565360055209
Mycobacterium avium subsp. paratuberculosis K10  MAP_4305  AAS06855.1  Q73RX3  306 aa hypothetical protein n.s. ●●○○○ -1.37 -1.36556924671412
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2268  CBW18370.1  A0A0H3NDS8  yfbG  660 aa hypothetical lipopolysaccharide modification protein n.s. ●●○○○ -1.37 -1.36501276275565
Escherichia coli CFT073  c1483  AAN79952.1  A0A0H2V6I0  314 aa Putative integrase of prophage n.s. ●●○○○ -1.36 -1.36450349322116
Escherichia coli CFT073  c1484  AAN79953.1  A0A0H2V6P1  88 aa Unknown protein encoded by prophage n.s. ●●○○○ -1.36 -1.36450349322116
Streptococcus pyogenes M1 5448  SP5448_06835  WP_010922098.1  240 aa GntR family transcriptional regulator n.s. ●●○○○ -1.36 -1.36431304907298
Streptococcus pyogenes M1 5448  SP5448_06920  WP_010922045.1  211 aa bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase n.s. ●●○○○ -1.36 -1.36431304907298
Vibrio parahaemolyticus RIMD 2210633  VP_0687  BAC58950.1  Q87RT9  294 aa geranyltranstransferase n.s. ●●○○○ -1.36 -1.36431113576654
Streptococcus pyogenes M1 5448  SP5448_05945  WP_002984898.1  58 aa DUF3042 family protein n.s. ●●○○○ -1.36 -1.36335171257491
Streptococcus pyogenes M1 5448  SP5448_05945  WP_047343331.1  299 aa tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA n.s. ●●○○○ -1.36 -1.36335171257491
Escherichia coli CFT073  c1873  AAN80335.1  A0A0H2V8H2  yncA  193 aa Hypothetical acetyltransferase yncA n.s. ●●○○○ -1.36 -1.36297227702747
Serratia marcescens Strain UMH9  BVG96_20005  ASL99763.1  339 aa glycerol-3-phosphate dehydrogenase n.s. ●●○○○ -1.36 -1.36226563485503
Serratia marcescens Strain UMH9  BVG96_06530  ASL97290.1  509 aa sodium-independent anion transporter n.s. ●●○○○ -1.36 -1.36207624140089
Serratia marcescens Strain UMH9  BVG96_16885  ASL99193.1  627 aa pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase n.s. ●●○○○ -1.36 -1.36203628098509
Escherichia coli O157:H7 str. EDL933  Z4807  AAG58548.1  231 aa orf, hypothetical protein n.s. ●●○○○ -1.36 -1.36202931435346
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1969  CBW18066.1  A0A0H3NEG4  275 aa predicted bacteriophage protein n.s. ●●○○○ -1.36 -1.36177369058315
Mycobacterium avium subsp. paratuberculosis K10  MAP_0937  AAS03254.1  Q742A0  188 aa hypothetical protein n.s. ●●○○○ -1.36 -1.3613349170429
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5043  AIK83569.1  353 aa histidinol-phosphate transaminase n.s. ●●○○○ -1.36 -1.3612353357776
Mycobacterium avium subsp. paratuberculosis K10  MAP_0278  AAS02595.1  Q745S6  173 aa hypothetical protein n.s. ●●○○○ -1.36 -1.36107155376881
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2531  CBW18631.1  A0A0H3NKI3  yfhB  211 aa hypothetical membrane protein n.s. ●●○○○ -1.36 -1.36071433060925
Streptococcus pyogenes M1 5448  SP5448_06165  WP_002984985.1  222 aa response regulator transcription factor n.s. ●●○○○ -1.36 -1.36046770308072
Mycobacterium avium subsp. paratuberculosis K10  MAP_1626c  AAS03943.1  Q73ZH7  nanT  424 aa NanT n.s. ●●○○○ -1.36 -1.36040213109713
Serratia marcescens Strain UMH9  BVG96_04995  ASL97002.1  83 aa prevent-host-death protein n.s. ●●○○○ -1.36 -1.36018004128801
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1488  CBW17583.1  A0A0H3NLC1  691 aa glycogen debranching protein n.s. ●●○○○ -1.36 -1.36009943534818
Escherichia coli CFT073  c0032  AAN78532.1  P0AEM1  fkpB  149 aa FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase n.s. ●●○○○ -1.36 -1.35984004010349
Vibrio parahaemolyticus RIMD 2210633  VPA_1210  BAC62553.1  Q87GV5  159 aa hypothetical protein n.s. ●●○○○ -1.36 -1.35982263586225
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1690  CBW17785.1  A0A0H3NLX0  narJ  236 aa respiratory nitrate reductase 1 delta chain n.s. ●●○○○ -1.36 -1.35966551957367
Escherichia coli CFT073  c2210  AAN80669.1  P0AA92  yeaY  193 aa Hypothetical lipoprotein yeaY precursor n.s. ●●○○○ -1.36 -1.3595989188892
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0041  CBW16142.1  A0A0H3N7D0  nhaR  299 aa transcriptional activator protein NhaR n.s. ●●○○○ -1.36 -1.35935697194266
Escherichia coli O157:H7 str. EDL933  Z0331  AAG54590.1  188 aa unknown protein encoded in prophage CP-933I n.s. ●●○○○ -1.36 -1.35882781850181
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0061  CBW16162.1  A0A0H3N8W0  citE2  289 aa citrate lyase beta chain n.s. ●●○○○ -1.36 -1.3583901995197
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0159  WP_002868941.1  A0A0H3PAU3  328 aa hypothetical protein n.s. ●●○○○ -1.36 -1.35752084604
Mycobacterium avium subsp. paratuberculosis K10  MAP_2941c  AAS05258.1  Q73VS0  409 aa hypothetical protein n.s. ●●○○○ -1.36 -1.35710699329386
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