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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli O157:H7 str. EDL933  Z4356  AAG58139.1  294 aa putative oxidoreductase n.s. ●●○○○ -1.36 -1.35613728419056
Escherichia coli CFT073  c2306  AAN80765.1  P0ABY8  flhC  192 aa Flagellar transcriptional activator flhC n.s. ●●○○○ -1.36 -1.35602101329032
Mycobacterium avium subsp. paratuberculosis K10  MAP_2185c  AAS04502.1  Q73XX3  409 aa hypothetical protein n.s. ●●○○○ -1.36 -1.35530255112708
Streptococcus pyogenes M1 5448  SP5448_04295  WP_010922387.1  435 aa sugar ABC transporter permease n.s. ●●○○○ -1.35 -1.35469968409233
Escherichia coli CFT073  c0389  AAN78870.1  P0A7B6  proB  380 aa Glutamate 5-kinase n.s. ●●○○○ -1.35 -1.35428773294545
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0909  WP_011812746.1  A0A0H3PHK7  59 aa hypothetical protein n.s. ●●○○○ -1.35 -1.35359367581
Mycobacterium avium subsp. paratuberculosis K10  MAP_0012c  AAS02329.1  Q744S0  141 aa hypothetical protein n.s. ●●○○○ -1.35 -1.35339797599374
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1081  WP_002853490.1  A0A0H3PD19  362 aa CinA family protein n.s. ●●○○○ -1.35 -1.35288726024
Escherichia coli CFT073  c1817  AAN80281.1  A0A0H2V8C0  dbpA  457 aa ATP-independent RNA helicase dbpA n.s. ●●○○○ -1.35 -1.35251456017587
Escherichia coli M12  CO715_08335  ATI05719.1  74 aa cold-shock protein CspD n.s. ●●○○○ -1.35 -1.3523529531324
Mycobacterium avium subsp. paratuberculosis K10  MAP_1926c  AAS04243.1  Q73YM9  377 aa hypothetical protein n.s. ●●○○○ -1.35 -1.35153982041249
Escherichia coli CFT073  c0936  AAN79409.1  A0A0H2V6C1  187 aa Hypothetical protein n.s. ●●○○○ -1.35 -1.35100543919901
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3714  CBW19808.1  A0A0H3NHG5  yicH  569 aa hypothetical exported protein n.s. ●●○○○ -1.35 -1.35092984459939
Streptococcus pyogenes M1 5448  SP5448_08455  WP_010922674.1  243 aa transaldolase n.s. ●●○○○ -1.35 -1.35085433810007
Streptococcus pyogenes M1 5448  SP5448_07370  WP_010921988.1  382 aa acetyl-CoA C-acyltransferase n.s. ●●○○○ -1.35 -1.35085433810007
Vibrio parahaemolyticus RIMD 2210633  VP_0691  BAC58954.1  Q87RT6  thiI  482 aa thiamin biosynthesis protein ThiI n.s. ●●○○○ -1.35 -1.35084823555824
Serratia marcescens Strain UMH9  BVG96_09980  ASL97927.1  335 aa sugar ABC transporter substrate-binding protein n.s. ●●○○○ -1.35 -1.35055095345317
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1517  CBW17611.1  A0A0H3NGT8  353 aa possible ATP-binding protein n.s. ●●○○○ -1.35 -1.35042613886227
Escherichia coli CFT073  c2244  AAN80703.1  Q8FGS9  rsmF  481 aa Hypothetical protein yebU n.s. ●●○○○ -1.35 -1.35041719707509
Escherichia coli CFT073  c1735  AAN80201.1  P0A9H6  btuR  196 aa COB(I)alamin adenosyltransferase n.s. ●●○○○ -1.35 -1.35033212777171
Vibrio parahaemolyticus RIMD 2210633  VP_0193  BAC58456.1  Q87T77  255 aa putative lipopolysaccharide biosynthesis glycosyltransferase n.s. ●●○○○ -1.35 -1.35029943872928
Acinetobacter baumannii ATCC 17978  A1S_0350  ABO10810.1  315 aa S-adenosylmethionine : 2-DMK methyltransferase and 2-octaprenyl-6-methoxy-14-benzoquinone methylase n.s. ●●○○○ -1.35 -1.35025952033043
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0351  CBW16451.1  A0A0H3NDE0  417 aa hypothetical metabolite transport protein n.s. ●●○○○ -1.35 -1.35010002522034
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4190  CBW20277.1  A0A0H3NP98  uvrA  941 aa excision nuclease subunit A n.s. ●●○○○ -1.35 -1.35005699737736
Escherichia coli CFT073  c2078  AAN80538.1  A0A0H2V9X7  ynhE  508 aa SufB protein n.s. ●●○○○ -1.35 -1.3493779759404
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2957  CBW19056.1  A0A0H3NFJ9  fucK  472 aa L-fuculose kinase n.s. ●●○○○ -1.35 -1.3492209630029
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1496  CBW17591.1  A0A0H3NGR7  sfcA  565 aa NAD-linked malic enzyme; malate oxidoreductase n.s. ●●○○○ -1.35 -1.3490702578797
Mycobacterium avium subsp. paratuberculosis K10  MAP_0216  AAS02533.1  I3NIE0  fbpA  347 aa FbpA n.s. ●●○○○ -1.35 -1.34863831500786
Mycobacterium avium subsp. paratuberculosis K10  MAP_3265  AAS05813.1  Q73UV1  434 aa hypothetical protein n.s. ●●○○○ -1.35 -1.34817903822503
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1499  CBW17594.1  A0A0H3ND55  fdnH  294 aa formate dehydrogenase, nitrate-inducible, iron-sulfur subunit (formate dehydrogenase-n beta subunit) (fdh-n beta subunit) (anaerobic formate dehydrogenase iron-sulfur subunit) n.s. ●●○○○ -1.35 -1.34794225992925
Mycobacterium avium subsp. paratuberculosis K10  MAP_0528  AAS02845.1  Q743R3  279 aa hypothetical protein n.s. ●●○○○ -1.35 -1.34789595534054
Serratia marcescens Strain UMH9  BVG96_05560  ASL97110.1  71 aa hypothetical protein n.s. ●●○○○ -1.35 -1.34747057997875
Escherichia coli CFT073  c1656  AAN80121.1  A0A0H2V6V5  ycgC  474 aa Hypothetical protein ycgC n.s. ●●○○○ -1.35 -1.34746448303777
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1553  CBW17648.1  A0A0H3NLH4  502 aa hypothetical esterase n.s. ●●○○○ -1.35 -1.34742722509539
Vibrio parahaemolyticus RIMD 2210633  VP_0293  BAC58556.1  Q87SX9  cysN  476 aa sulfate adenylate transferase, subunit 1 n.s. ●●○○○ -1.35 -1.34740427704339
Escherichia coli CFT073  c2458  AAN80917.1  A0A0H2V8L8  2154 aa Putative peptide synthetase n.s. ●●○○○ -1.35 -1.34694141658968
Serratia marcescens Strain UMH9  BVG96_13655  ASL98610.1  361 aa chorismate synthase n.s. ●●○○○ -1.35 -1.34688415119879
Escherichia coli O157:H7 str. EDL933  Z4185  AAG57977.1  373 aa putative integral membrane protein-component of type III secretion apparatus n.s. ●●○○○ -1.35 -1.34680973795729
Escherichia coli M12  CO715_08430  ATI05735.1  171 aa lipoprotein n.s. ●●○○○ -1.35 -1.34546763466219
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1225  WP_002852725.1  A0A0H3P9P5  yihY  268 aa YihY/virulence factor BrkB family protein n.s. ●●○○○ -1.35 -1.34540418445
Serratia marcescens Strain UMH9  BVG96_09165  ASL97776.1  408 aa Zn-dependent hydrolase n.s. ●●○○○ -1.34 -1.34476198656345
Escherichia coli CFT073  c0028  AAN78528.1  A0A0H2V3X0  yaaY  72 aa Hypothetical protein yaaY n.s. ●●○○○ -1.34 -1.34377215631826
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4021  CBW20110.1  A0A0H3NNT2  ydeV  530 aa hypothetical sugar kinase n.s. ●●○○○ -1.34 -1.34361682045918
Escherichia coli CFT073  c1993  AAN80453.1  A0A0H2V7G7  344 aa Hypothetical protein ydgG n.s. ●●○○○ -1.34 -1.34299914157534
Escherichia coli CFT073  c1149  AAN79617.1  Q8FJ41  rutA  393 aa Putative monooxygenase ycdM n.s. ●●○○○ -1.34 -1.34265025564968
Escherichia coli O157:H7 str. EDL933  Z0728  AAG54922.1  377 aa ferric enterobactin (enterochelin) transport n.s. ●●○○○ -1.34 -1.34231754142021
Mycobacterium avium subsp. paratuberculosis K10  MAP_3888c  AAS06438.1  Q73T31  460 aa hypothetical protein n.s. ●●○○○ -1.34 -1.34211542318806
Escherichia coli CFT073  c4049  AAN82487.1  Q8FD12  rsmB  429 aa SUN protein n.s. ●●○○○ -1.34 -1.34154410863815
Escherichia coli O157:H7 str. EDL933  Z5029  AAG58749.1  1588 aa putative adhesin n.s. ●●○○○ -1.34 -1.34142518743185
Serratia marcescens Strain UMH9  BVG96_15700  ASM00562.1  887 aa bifunctional uridylyltransferase/uridylyl-removing protein n.s. ●●○○○ -1.34 -1.3413981585632
Haemophilus influenzae Rd KW20  HI_1207  NP_439363.1  P43854  purF  505 aa amidophosphoribosyltransferase n.s. ●●○○○ -1.34 -1.34135364168626
Streptococcus pyogenes M1 5448  SP5448_02690  WP_011285662.1  542 aa ABC transporter permease n.s. ●●○○○ -1.34 -1.34124097311942
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1230  WP_002868858.1  A0A0H3PAI2  226 aa polyphenol oxidase n.s. ●●○○○ -1.34 -1.3400575034
Escherichia coli O157:H7 str. EDL933  Z4964  AAG58689.1  574 aa orf, hypothetical protein n.s. ●●○○○ -1.34 -1.34004946341081
Mycobacterium avium subsp. paratuberculosis K10  MAP_1162  AAS03479.1  Q741C9  581 aa hypothetical protein n.s. ●●○○○ -1.34 -1.33968202419575
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4351  CBW20437.2  A0A0H3NW06  iolT1  456 aa myo-inositol transport n.s. ●●○○○ -1.34 -1.33850438063646
Escherichia coli CFT073  c2153  AAN80612.1  A0A0H2V7S4  ydjZ  235 aa Hypothetical protein ydjZ n.s. ●●○○○ -1.34 -1.33834580794018
Escherichia coli O157:H7 str. EDL933  Z3435  AAG57314.1  518 aa orf, hypothetical protein n.s. ●●○○○ -1.34 -1.33776691603852
Streptococcus pyogenes M1 5448  SP5448_03405  WP_010922486.1  284 aa bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase n.s. ●●○○○ -1.34 -1.33739562712716
Vibrio parahaemolyticus RIMD 2210633  VPA_0879  BAC62222.1  Q87HS7  338 aa UDP-glucose 4-epimerase n.s. ●●○○○ -1.34 -1.33729386291615
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3502  CBW19596.1  A0A0H3NMN6  glgA  477 aa glycogen synthase n.s. ●●○○○ -1.34 -1.33715518879678
Escherichia coli M12  CO715_20270  ATI07852.1  52 aa hypothetical protein n.s. ●●○○○ -1.34 -1.33691314807799
Escherichia coli CFT073  c2941  AAN81391.1  A0A0H2V9H1  yfeN  320 aa Hypothetical protein yfeN n.s. ●●○○○ -1.34 -1.33647539718758
Haemophilus influenzae Rd KW20  HI_0518  NP_438676.1  P44417  deoD  238 aa purine nucleoside phosphorylase n.s. ●●○○○ -1.34 -1.33603975905329
Escherichia coli O157:H7 str. EDL933  Z0078  AAG54373.1  189 aa hypothetical protein n.s. ●●○○○ -1.34 -1.33546812271811
Mycobacterium avium subsp. paratuberculosis K10  MAP_2848c  AAS05165.1  P62219  recA  409 aa RecA n.s. ●●○○○ -1.33 -1.33469643255717
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2283  CBW18385.1  A0A0H3NDU3  333 aa hypothetical receptor/regulator protein n.s. ●●○○○ -1.33 -1.3346717684661
Mycobacterium avium subsp. paratuberculosis K10  MAP_0609  AAS02926.1  Q743H6  205 aa hypothetical protein n.s. ●●○○○ -1.33 -1.3346049204977
Streptococcus pyogenes M1 5448  SP5448_03715  WP_011285615.1  622 aa hypothetical protein n.s. ●●○○○ -1.33 -1.33451161763297
Escherichia coli CFT073  c1191  AAN79653.1  A0A0H2V614  772 aa Conserved hypothetical protein n.s. ●●○○○ -1.33 -1.33450722522773
Escherichia coli O157:H7 str. EDL933  Z3277  AAG57170.1  826 aa putative outer membrane protein n.s. ●●○○○ -1.33 -1.33431709291201
Mycobacterium avium subsp. paratuberculosis K10  MAP_2416c  AAS04733.1  Q73X93  557 aa hypothetical protein n.s. ●●○○○ -1.33 -1.33383122863269
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3463  AIK82019.1  249 aa triose-phosphate isomerase n.s. ●●○○○ -1.33 -1.33360806081916
Escherichia coli O157:H7 str. EDL933  Z0095  AAG54389.1  495 aa meso-diaminopimelate-adding enzyme n.s. ●●○○○ -1.33 -1.33315285052978
Mycobacterium avium subsp. paratuberculosis K10  MAP_1019  AAS03336.1  Q741R8  283 aa hypothetical protein n.s. ●●○○○ -1.33 -1.33301072069959
Escherichia coli CFT073  c2142  AAN80601.1  A0A0H2V926  162 aa Hypothetical protein n.s. ●●○○○ -1.33 -1.33286305740048
Escherichia coli CFT073  c2143  AAN80602.1  A0A0H2V7R8  spy  161 aa Spheroplast protein Y precursor n.s. ●●○○○ -1.33 -1.33286305740048
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0716  WP_079254184.1  A1VZ48  rsmH  312 aa 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH n.s. ●●○○○ -1.33 -1.33265667016
Streptococcus pyogenes M1 5448  SP5448_03105  WP_002983750.1  84 aa DUF1912 family protein n.s. ●●○○○ -1.33 -1.33258894463684
Streptococcus pyogenes M1 5448  SP5448_01205  WP_002885866.1  44 aa 50S ribosomal protein L34 n.s. ●●○○○ -1.33 -1.33258894463684
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4309  CBW20395.1  A0A0H3NVW0  yjfC  387 aa conserved hypothetical protein n.s. ●●○○○ -1.33 -1.332446335643
Mycobacterium avium subsp. paratuberculosis K10  MAP_3154  AAS05702.1  Q73V62  selO  491 aa hypothetical protein n.s. ●●○○○ -1.33 -1.33236836481088
Escherichia coli CFT073  c1711  AAN80178.1  A0A0H2V854  oppF  334 aa Oligopeptide transport ATP-binding protein oppF n.s. ●●○○○ -1.33 -1.33224618594068
Escherichia coli CFT073  c2358  AAN80817.1  A0A0H2V887  fliI  457 aa Flagellum-specific ATP synthase n.s. ●●○○○ -1.33 -1.33224618594068
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1436  WP_024088151.1  A0A0H3P9U3  723 aa glycosyltransferase n.s. ●●○○○ -1.33 -1.33192283794
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4478  CBW20567.1  A0A0H3NWE8  yjjQ  241 aa conserved hypothetical regulatory protein n.s. ●●○○○ -1.33 -1.33176371650528
Streptococcus pyogenes M1 5448  SP5448_05040  WP_002993300.1  232 aa helix-turn-helix transcriptional regulator n.s. ●●○○○ -1.33 -1.33162760813877
Escherichia coli CFT073  c0942  AAN79415.1  Q8FJJ0  804 aa Putative replication protein for prophage n.s. ●●○○○ -1.33 -1.33158933124085
Vibrio parahaemolyticus RIMD 2210633  VP_1560  BAC59823.1  Q87PE8  38 aa hypothetical protein n.s. ●●○○○ -1.33 -1.33150062689276
Serratia marcescens Strain UMH9  BVG96_02120  ASL96476.1  201 aa recombination protein RecR n.s. ●●○○○ -1.33 -1.33136821839971
Escherichia coli O157:H7 str. EDL933  Z5108  AAG58821.1  351 aa sepL n.s. ●●○○○ -1.33 -1.33106827810504
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1035  CBW17131.1  A0A0H3NA21  copR  248 aa response regulator n.s. ●●○○○ -1.33 -1.33063513452583
Escherichia coli CFT073  c2557  AAN81012.1  A0A0H2VA01  manB  456 aa Phosphomannomutase n.s. ●●○○○ -1.33 -1.32998288221733
Escherichia coli CFT073  c2192  AAN80651.1  A0A0H2V975  yeaK  167 aa Hypothetical protein yeaK n.s. ●●○○○ -1.33 -1.32958903269057
Escherichia coli CFT073  c2737  AAN81191.1  P0ABL9  ccmB  220 aa Heme exporter protein B n.s. ●●○○○ -1.33 -1.32958903269057
Escherichia coli O157:H7 str. EDL933  Z5897  AAG59483.1  1117 aa hypothetical protein n.s. ●●○○○ -1.33 -1.328473395879
Escherichia coli O157:H7 str. EDL933  Z0897  AAG55066.1  140 aa hypothetical protein n.s. ●●○○○ -1.33 -1.32847191249704
Escherichia coli O157:H7 str. EDL933  Z2719  AAG56678.1  423 aa putative amino acid/amine transport protein n.s. ●●○○○ -1.33 -1.32847191249704
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3559  CBW19653.1  A0A0H3NTD0  prlC  680 aa oligopeptidase A n.s. ●●○○○ -1.33 -1.32838954366139
Mycobacterium avium subsp. paratuberculosis K10  MAP_2705c  AAS05022.1  Q73WF5  127 aa hypothetical protein n.s. ●●○○○ -1.33 -1.32815804624005
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