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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli CFT073  c2392  AAN80851.1  A0A0H2VAK2  406 aa Putative P4-family integrase 0.036 ●●●○○ -2.91 -2.90909801547975
Escherichia coli CFT073  c1855  AAN80318.1  A0A0H2V768  42 aa Hypothetical protein 0.014 ●●●○○ -2.77 -2.76535015900051
Escherichia coli CFT073  c1757  AAN80223.1  Q8FHT6  rnb  644 aa Exoribonuclease II 0.045 ●●●○○ -2.74 -2.74356999449681
Escherichia coli CFT073  c1859  AAN80322.1  A0A0H2V8F8  ydcP  667 aa Putative protease ydcP precursor 0.024 ●●●○○ -2.6 -2.59613185008052
Escherichia coli CFT073  c2601  AAN81057.1  Q8FG04  mdtB  1040 aa Hypothetical protein yegN 0.045 ●●●○○ -2.5 -2.4988482204782
Escherichia coli CFT073  c1789  AAN80255.1  A0A0H2V719  ycjU  219 aa Putative beta-phosphoglucomutase 0.028 ●●●○○ -2.43 -2.42794949137612
Escherichia coli CFT073  c2511  AAN80966.1  A0A0H2V8L6  260 aa Insertion sequence ATP-binding protein 0.03 ●●●○○ -2.43 -2.4278188343889
Escherichia coli CFT073  c1698  AAN80165.1  A0A0H2V6X7  ychK  314 aa Hypothetical protein ychK 0.028 ●●●○○ -2.37 -2.37395961884861
Escherichia coli CFT073  c1050  AAN79520.1  P0A6Y2  ihfB  94 aa Integration host factor beta-subunit 0.04 ●●●○○ -2.35 -2.34501254411669
Escherichia coli CFT073  c2512  AAN80967.1  A0A0H2V9X1  340 aa Transposase 0.027 ●●●○○ -2.31 -2.31369181848396
Escherichia coli CFT073  c2091  AAN80551.1  A0A0H2V9Y8  ydiP  303 aa Hypothetical transcriptional regulator ydiP 0.049 ●●●○○ -2.28 -2.28465069810588
Escherichia coli CFT073  c1975  AAN80435.1  Q8FHC4  ynfC  248 aa Hypothetical protein ynfC 0.036 ●●●○○ -2.24 -2.23928692714784
Escherichia coli CFT073  c1923  AAN80381.1  A0A0H2V7F0  pqqL  931 aa Probable zinc protease pqqL 0.05 ●●●○○ -2.19 -2.18810903513216
Escherichia coli CFT073  c1219  AAN79679.1  A0A0H2V853  249 aa Putative Transposase 0.0026 ●●●○○ -2.14 -2.13585448563834
Escherichia coli CFT073  c2608  AAN81064.1  A0A0H2V8X8  715 aa Hypothetical protein 0.02 ●●●○○ -2.07 -2.07079285334062
Escherichia coli CFT073  c2037  AAN80497.1  A0A0H2V7L5  ydhK  670 aa Hypothetical protein ydhK 0.024 ●●●○○ -2.03 -2.02746009675828
Escherichia coli CFT073  c2239  AAN80698.1  A0A0H2V7Z4  prc  682 aa Tail-specific protease precursor 0.048 ●●●○○ -2.02 -2.02398755611562
Escherichia coli CFT073  c2400  AAN80859.1  A0A0H2V895  278 aa Hypothetical protein 0.047 ●●○○○ -1.95 -1.95444642070828
Escherichia coli CFT073  c1924  AAN80382.1  A0A0H2V8M0  yddB  790 aa Hypothetical protein yddB 0.026 ●●○○○ -1.94 -1.93804911859107
Escherichia coli CFT073  c2775  AAN81229.1  A0A0H2V8Z9  yfaL  1254 aa Hypothetical protein yfaL precursor 0.0054 ●●○○○ -1.94 -1.9363212652982
Escherichia coli CFT073  c1694  AAN80161.1  A0A0H2V6Z5  374 aa Hypothetical protein 0.037 ●●○○○ -1.87 -1.87079187279587
Escherichia coli CFT073  c2568  AAN81023.1  A0A0H2V8L7  wcaM  464 aa Colanic acid biosynthesis protein wcaM 0.03 ●●○○○ -1.84 -1.83999621444471
Escherichia coli CFT073  c2090  AAN80550.1  P0A9U9  ydiO  401 aa Hypothetical protein ydiO 0.046 ●●○○○ -1.82 -1.81813194001185
Escherichia coli CFT073  c2797  AAN81251.1  Q8FFM1  arnA  660 aa Hypothetical protein yfbG 0.045 ●●○○○ -1.74 -1.74187972640173
Escherichia coli CFT073  c1769  AAN80235.1  P0AGH6  sapC  296 aa Peptide transport system permease protein sapC 0.033 ●●○○○ -1.73 -1.7335864746034
Escherichia coli CFT073  c2549  AAN81004.1  Q8FG50  hisB  356 aa Histidine biosynthesis bifunctional protein hisB 0.049 ●●○○○ -1.7 -1.70456764193481
Escherichia coli CFT073  c2387  AAN80846.1  A0A0H2V9L4  yedW  260 aa Probable transcriptional Regulatory protein yedW 0.0091 ●●○○○ -1.69 -1.69115048912322
Escherichia coli CFT073  c1828  AAN80292.1  A0A0H2V9G9  ydbH  879 aa Hypothetical protein ydbH 0.046 ●●○○○ -1.63 -1.63229374617902
Escherichia coli CFT073  c2486  AAN80945.1  A0A0H2VAU5  236 aa Hypothetical protein 0.0084 ●●○○○ -1.6 -1.60296681616611
Escherichia coli CFT073  c1603  AAN80071.1  A0A0H2V7Y7  ycgX  134 aa Hypothetical protein ycgX 0.018 ●●○○○ -1.51 -1.50843214233074
Escherichia coli CFT073  c1836  AAN80299.1  A0A0H2V781  ynbC  585 aa Hypothetical protein ynbC 0.027 ●●○○○ -1.47 -1.46750124325595
Escherichia coli CFT073  c1928  AAN80386.1  Q8FHG0  ydeO  253 aa Hypothetical transcriptional regulator ydeO 0.045 ●●○○○ -1.28 -1.28438995791605
Escherichia coli CFT073  c2627  AAN81083.1  A0A0H2VA83  yegV  321 aa Hypothetical sugar kinase yegV 0.01 ●●○○○ -1.21 -1.21274660566679
Escherichia coli CFT073  c2256  AAN80715.1  A0A0H2V9B4  ptrB  554 aa Protease II 0.024 ●●○○○ -1.21 -1.21116371986542
Escherichia coli CFT073  c1020  AAN79492.1  A0A0H2V5P1  130 aa Hypothetical protein 0.026 ●●○○○ -1.19 -1.19234503212158
Escherichia coli CFT073  c2447  AAN80906.1  A0A0H2V8C7  cbl  316 aa Transcriptional regulator cbl 0.037 ●●○○○ -1.19 -1.18661712147746
Escherichia coli CFT073  c1857  AAN80320.1  A0A0H2V9I3  ydcO  431 aa Hypothetical protein ydcO 0.022 ●●○○○ -1.17 -1.16646771013607
Escherichia coli CFT073  c1681  AAN80148.1  P0AF29  narL  238 aa Nitrate/nitrite response regulator protein narL 0.039 ●●○○○ -1.08 -1.08425452854305
Escherichia coli CFT073  c1764  AAN80230.1  A0A0H2V703  1005 aa Acriflavine resistance protein B 0.042 ●●○○○ -1.05 -1.04870416469947
Escherichia coli CFT073  c3025  AAN81475.1  A0A0H2V9E3  yfgI  179 aa Hypothetical protein yfgI 0.032 ●●○○○ -1.03 -1.03089290875703
Escherichia coli CFT073  c2036  AAN80496.1  A0A0H2V9U6  ydhJ  299 aa Hypothetical protein ydhJ 0.011 ●●○○○ -1.03 -1.02756706771692
Escherichia coli CFT073  c1889  AAN80349.1  A0A0H2V7C5  200 aa Hypothetical protein 0.0087 ●●○○○ -1 -1.00414811639419
Escherichia coli CFT073  c1688  AAN80155.1  A0A0H2V978  narI  225 aa Respiratory nitrate reductase 1 gamma chain 0.039 ●○○○○ -1 -0.997330890775445
Escherichia coli CFT073  c2478  AAN80937.1  Q8FGA4  cobS  259 aa Cobalamin [5'-phosphate] synthase 0.02 ●○○○○ -0.99 -0.987469748599242
Escherichia coli CFT073  c1853  AAN80316.1  A0A0H2V795  tehA  366 aa Tellurite resistance protein tehA 0.014 ●○○○○ -0.97 -0.972832484885002
Escherichia coli CFT073  c0862  AAN79335.1  P65382  moaA  356 aa Molybdenum cofactor biosynthesis protein A 0.042 ●○○○○ -0.94 -0.935137912171921
Escherichia coli CFT073  c1788  AAN80254.1  A0A0H2V8A1  ycjT  755 aa Hypothetical transport protein ycjT 0.033 ●○○○○ -0.83 -0.832567171437336
Escherichia coli CFT073  c2208  AAN80667.1  A0A0H2V985  rnd  375 aa Ribonuclease D 0.019 ●○○○○ -0.81 -0.807510359075225
Escherichia coli CFT073  c1251  AAN79708.1  A0A0H2V871  iroE  318 aa IroE protein 9.9e-8 ●○○○○ -0.66 -0.664731817296556
Escherichia coli CFT073  c2052  AAN80512.1  Q8FH72  purR  341 aa Purine nucleotide synthesis repressor 0.015 ●○○○○ -0.6 -0.604873933882396
Escherichia coli CFT073  c3047  AAN81497.1  A0A0H2VAZ2  sseB  261 aa Protein sseB 0.046 ●○○○○ -0.54 -0.540651078392893
Escherichia coli CFT073  c1818  AAN80282.1  Q8FHP6  ttcA  311 aa Hypothetical protein ydaO 0.045 ●○○○○ -0.4 -0.396788504792042
Escherichia coli CFT073  c2679  AAN81135.1  A0A0H2VAB5  yeiT  412 aa Hypothetical oxidoreductase yeiT 0.0057 ●○○○○ -0.39 -0.394271478254985
Escherichia coli CFT073  c1998  AAN80458.1  Q8FHB1  folM  240 aa Hypothetical oxidoreductase ydgB 0.026 ●○○○○ -0.23 -0.227929560619045
Escherichia coli CFT073  c0426  AAN78907.1  A0A0H2V5A3  776 aa Hypothetical protein 9.3e-30 ●○○○○ -0.19 -0.194958766480295
Escherichia coli CFT073  c2611  AAN81067.1  A0A0H2VA75  yegQ  453 aa Putative protease yegQ 0.022 ●○○○○ -0.16 -0.157375175551683
Escherichia coli CFT073  c1591  AAN80059.1  A0A0H2V6V1  555 aa Hypothetical protein 0.05 ●○○○○ -0.15 -0.146536264707635
Escherichia coli CFT073  c2510  AAN80965.1  A0A0H2VAW1  117 aa Hypothetical protein 0.021 ●○○○○ -0.12 -0.116293482497535
Escherichia coli CFT073  c1047  AAN79517.1  A0A0H2V5T1  ycaL  257 aa Putative metalloprotease ycaL 0.04 ●○○○○ -0.1 -0.101481621762338
Escherichia coli CFT073  c1996  AAN80456.1  A0A0H2V9S5  ydgH  314 aa Protein ydgH precursor 0.033 ●○○○○ -0.05 -0.0473473145521664
Escherichia coli CFT073  c1220  AAN79680.1  A0A0H2V636  358 aa Phospho-2-dehydro-3-deoxyheptonate aldolase, Trp-sensitive n.s. ●●●●○ -3.31 -3.30887333363685
Escherichia coli CFT073  c2777  AAN81231.1  A0A0H2VBE1  nrdB  376 aa Ribonucleoside-diphosphate reductase 1 beta chain n.s. ●●●●○ -3.08 -3.08066843304621
Escherichia coli CFT073  c2680  AAN81136.1  A0A0H2V8T8  yeiA  413 aa Hypothetical protein yeiA n.s. ●●●●○ -3.06 -3.06263133049765
Escherichia coli CFT073  c2349  AAN80808.1  A0A0H2V8D4  ybcM  265 aa Hypothetical transcriptional regulator ybcM n.s. ●●●●○ -3.01 -3.01009431990919
Escherichia coli CFT073  c2492  AAN80948.1  A0A0H2V8G3  rbsK  404 aa Putative carbohydrate kinase n.s. ●●●○○ -2.94 -2.93504797986976
Escherichia coli CFT073  c1891  AAN80351.1  A0A0H2V798  168 aa Hypothetical protein n.s. ●●●○○ -2.92 -2.92246923165729
Escherichia coli CFT073  c2628  AAN81084.1  P0ACM6  yegW  248 aa Hypothetical transcriptional regulator yegW n.s. ●●●○○ -2.88 -2.87508045615795
Escherichia coli CFT073  c1856  AAN80319.1  A0A0H2V7H3  ydcL  222 aa Hypothetical lipoprotein ydcL precursor n.s. ●●●○○ -2.77 -2.76535015900051
Escherichia coli CFT073  c2055  AAN80515.1  P0A9H8  cfa  382 aa Cyclopropane-fatty-acyl-phospholipid synthase n.s. ●●●○○ -2.72 -2.72458118763976
Escherichia coli CFT073  c1606  AAN80074.1  A0A0H2V936  ycgF  429 aa Hypothetical protein ycgF n.s. ●●●○○ -2.66 -2.65752650051482
Escherichia coli CFT073  c2209  AAN80668.1  P69452  fadD  583 aa Long-chain-fatty-acid--CoA ligase n.s. ●●●○○ -2.65 -2.64741134434246
Escherichia coli CFT073  c1162  AAN79630.1  A0A0H2V5Y9  ycdR  672 aa Hypothetical lipoprotein ycdR precursor n.s. ●●●○○ -2.59 -2.59222274006338
Escherichia coli CFT073  c2613  AAN81069.1  A0A0H2V8Y3  yegR  110 aa Hypothetical protein yegR n.s. ●●●○○ -2.59 -2.58567957610021
Escherichia coli CFT073  c2001  AAN80461.1  A0A0H2V7H2  rstB  433 aa Sensor protein rstB n.s. ●●●○○ -2.53 -2.52782180424617
Escherichia coli CFT073  c1025  AAN79497.1  A0A0H2V5S0  trxB  361 aa Thioredoxin reductase n.s. ●●●○○ -2.51 -2.51451736258756
Escherichia coli CFT073  c1837  AAN80300.1  A0A0H2V8D6  ynbD  463 aa Hypothetical protein ynbD n.s. ●●●○○ -2.51 -2.50627480809788
Escherichia coli CFT073  c2569  AAN81024.1  A0A0H2V8V0  wcaL  406 aa Putative colanic acid biosynthesis glycosyl transferase wcaL n.s. ●●●○○ -2.46 -2.46436801774304
Escherichia coli CFT073  c3027  AAN81477.1  A0A0H2V9L5  guaB  511 aa Inosine-5'-monophosphate dehydrogenase n.s. ●●●○○ -2.43 -2.43395156156867
Escherichia coli CFT073  c1771  AAN80237.1  A0A0H2V884  sapA  547 aa Peptide transport periplasmic protein sapA precursor n.s. ●●●○○ -2.42 -2.42179015723186
Escherichia coli CFT073  c1997  AAN80457.1  P0AAE6  ydgI  469 aa Putative arginine/ornithine antiporter n.s. ●●●○○ -2.42 -2.42106857972361
Escherichia coli CFT073  c2393  AAN80852.1  A0A0H2V8B2  606 aa Hypothetical protein n.s. ●●●○○ -2.39 -2.39344171000984
Escherichia coli CFT073  c2448  AAN80907.1  A0A0H2V8L0  yeeO  546 aa Hypothetical protein yeeO n.s. ●●●○○ -2.38 -2.37790705841798
Escherichia coli CFT073  c1682  AAN80149.1  A0A0H2V759  narX  598 aa Nitrate/nitrite sensor protein narX n.s. ●●●○○ -2.36 -2.36008902725441
Escherichia coli CFT073  c1689  AAN80156.1  A0A0H2V6Z2  347 aa Hypothetical protein n.s. ●●●○○ -2.35 -2.35461648867093
Escherichia coli CFT073  c1051  AAN79521.1  A0A0H2V6K7  102 aa Hypothetical protein n.s. ●●●○○ -2.35 -2.34501254411669
Escherichia coli CFT073  c0867  AAN79340.1  A0A0H2V5E8  moaE  150 aa Molybdopterin converting factor subunit 2 n.s. ●●●○○ -2.33 -2.32893613116313
Escherichia coli CFT073  c2798  AAN81252.1  Q8FFM0  arnD  296 aa Hypothetical protein yfbH n.s. ●●●○○ -2.3 -2.29513753167487
Escherichia coli CFT073  c3056  AAN81506.1  P0A6B8  iscS  412 aa Cysteine desulfurase n.s. ●●●○○ -2.29 -2.28737792178724
Escherichia coli CFT073  c1832  AAN80295.1  A0A0H2V8D0  ydbC  286 aa Hypothetical oxidoreductase ydbC n.s. ●●●○○ -2.28 -2.28097871181535
Escherichia coli CFT073  c2243  AAN80702.1  A0A0H2V855  yebT  891 aa Hypothetical protein yebT n.s. ●●●○○ -2.26 -2.2626115525078
Escherichia coli CFT073  c2094  AAN80554.1  A0A0H2V7N5  ydiR  312 aa Putative electron transfer flavoprotein subunit ydiR n.s. ●●●○○ -2.26 -2.2556127591194
Escherichia coli CFT073  c1598  AAN80066.1  A0A0H2V6S9  sitC  285 aa SitC protein n.s. ●●●○○ -2.25 -2.25082130147757
Escherichia coli CFT073  c1626  AAN80091.1  A0A0H2V6W9  ycgK  133 aa Protein ycgK precursor n.s. ●●●○○ -2.24 -2.2446064476398
Escherichia coli CFT073  c3043  AAN81493.1  A0A0H2V9F4  yfhM  1653 aa Hypothetical lipoprotein yfhM precursor n.s. ●●●○○ -2.24 -2.24220985307229
Escherichia coli CFT073  c1745  AAN80211.1  A0A0H2V9B9  acnA  891 aa Aconitate hydratase 1 n.s. ●●●○○ -2.24 -2.2408244543047
Escherichia coli CFT073  c1941  AAN80399.1  Q8FHF3  hipB  94 aa Protein hipB n.s. ●●●○○ -2.24 -2.23518173332348
Escherichia coli CFT073  c2044  AAN80504.1  A0A0H2V7M0  gloA  135 aa Lactoylglutathione lyase n.s. ●●●○○ -2.23 -2.23198148462411
Escherichia coli CFT073  c1795  AAN80261.1  A0A0H2V8A7  tyrR  522 aa Transcriptional Regulatory protein tyrR n.s. ●●●○○ -2.23 -2.22736126053441
Escherichia coli CFT073  c2733  AAN81187.1  A0A0H2V909  ccmF  647 aa Cytochrome c-type biogenesis protein ccmF n.s. ●●●○○ -2.22 -2.22436998467892
Escherichia coli CFT073  c1713  AAN80180.1  P0A6H9  clsA  486 aa Cardiolipin synthetase n.s. ●●●○○ -2.22 -2.22068675154077
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