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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4381  AIK82924.1  147 aa flavodoxin family protein <1e-323 ●○○○○ -0.16 -0.15925947067703
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2572  AIK81169.1  820 aa thrA <1e-323 ●○○○○ -0.16 -0.158978435570725
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4244  AIK82789.1  828 aa type VII secretion system (T7SS), usher family protein <1e-323 ●○○○○ -0.16 -0.157810510970939
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2837  AIK81426.1  175 aa acetyltransferase family protein <1e-323 ●○○○○ -0.16 -0.157180052889716
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2611  AIK81205.1  262 aa siderophore-iron reductase FhuF 3.2e-5 ●○○○○ -0.16 -0.156316672628085
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3077  AIK81662.1  594 aa aceK <1e-323 ●○○○○ -0.16 -0.155673097662103
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3184  AIK81752.1  376 aa TDP-4-keto-6-deoxy-D-glucose transaminase familyprotein <1e-323 ●○○○○ -0.16 -0.155651731808893
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4384  AIK82927.1  446 aa glucarate dehydratase 2.1e-14 ●○○○○ -0.15 -0.153666622342199
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3644  AIK82199.1  507 aa bacterial regulatory, gntR family protein <1e-323 ●○○○○ -0.15 -0.153648884842947
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3002  AIK81587.1  548 aa na+/H+ antiporter 2.3e-8 ●○○○○ -0.15 -0.152366921393709
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3402  AIK81959.1  367 aa 2-aminoethylphosphonate--pyruvate transaminase <1e-323 ●○○○○ -0.15 -0.151137369335066
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3967  AIK82515.1  332 aa putrescine aminotransferase 0.00056 ●○○○○ -0.15 -0.150675227080953
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4375  AIK82918.1  429 aa sdaC serine STP transporter <1e-323 ●○○○○ -0.15 -0.150416424180123
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2670  AIK81264.1  220 aa lysE type translocator family protein 2.8e-15 ●○○○○ -0.15 -0.149675892096414
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3544  AIK82100.1  331 aa acyltransferase family protein <1e-323 ●○○○○ -0.15 -0.14945599801004
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2708  AIK81298.1  1049 aa cusA 5.1e-10 ●○○○○ -0.15 -0.147544850903036
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4560  AIK83098.1  88 aa smpA 0.0012 ●○○○○ -0.15 -0.146627333803827
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4950  AIK83476.1  181 aa hypothetical protein 1.0e-12 ●○○○○ -0.14 -0.14452416120304
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2557  AIK81154.1  298 aa nhaR transcriptional activator 1.1e-12 ●○○○○ -0.14 -0.144281476264601
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3858  AIK82408.1  779 aa aerobic respiration control sensor protein arcB 2.2e-14 ●○○○○ -0.14 -0.143627070739349
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4203  AIK82748.1  500 aa response regulator <1e-323 ●○○○○ -0.14 -0.142602082076894
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1805  AIK80418.1  331 aa hypothetical protein 0.0067 ●○○○○ -0.14 -0.142326349096792
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3958  AIK82506.1  673 aa NADH:flavin oxidoreductase / NADH oxidase familyprotein 3.6e-7 ●○○○○ -0.14 -0.141226598804722
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2909  AIK81495.1  1109 aa mechanosensitive ion channel family protein 1.1e-16 ●○○○○ -0.14 -0.140909000486399
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2873  AIK81462.1  284 aa L-xylulose 5-phosphate 3-epimerase 1.4e-9 ●○○○○ -0.14 -0.139093193520401
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1641  AIK80261.1  133 aa hypothetical protein 1.3e-6 ●○○○○ -0.14 -0.139080858161556
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2489  AIK81086.1  163 aa acetolactate synthase, small subunit 1.9e-12 ●○○○○ -0.14 -0.138947693504572
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3233  AIK81794.1  287 aa bacterial regulatory helix-turn-helix, AraC family protein <1e-323 ●○○○○ -0.14 -0.138488150335977
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3324  AIK81881.1  330 aa aspartate--ammonia ligase 1.1e-13 ●○○○○ -0.14 -0.135904119685155
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3586  AIK82141.1  872 aa cellulose synthase catalytic subunit <1e-323 ●○○○○ -0.14 -0.135839022563125
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2125  AIK80730.1  353 aa malK 0.02 ●○○○○ -0.14 -0.135122283594329
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2664  AIK81258.1  67 aa hypothetical protein <1e-323 ●○○○○ -0.14 -0.135117918649995
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2228  AIK80833.1  105 aa psiF repeat family protein 2.8e-9 ●○○○○ -0.14 -0.135062329982098
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4885  AIK83412.1  365 aa outer membrane protein C <1e-323 ●○○○○ -0.13 -0.134852185067308
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2999  AIK81584.1  229 aa lrgB-like family protein 0.00014 ●○○○○ -0.13 -0.134040309902753
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4265  AIK82810.1  428 aa bacterial extracellular solute-binding family protein <1e-323 ●○○○○ -0.13 -0.133598865307495
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3190  AIK81758.1  338 aa chain length determinant family protein 1.7e-12 ●○○○○ -0.13 -0.132474998709326
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2300  AIK80904.1  512 aa badF/BadG/BcrA/BcrD ATPase family protein <1e-323 ●○○○○ -0.13 -0.131862586040249
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2438  AIK81035.1  536 aa multicopper oxidase with role in copper homeostasis <1e-323 ●○○○○ -0.13 -0.131774455020635
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2539  AIK81136.1  283 aa citrate (pro-3S)-lyase, beta subunit 0.0037 ●○○○○ -0.13 -0.131207425185653
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2784  AIK81373.1  43 aa hypothetical protein 0.014 ●○○○○ -0.13 -0.129322637532825
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2714  AIK81304.1  419 aa flavin containing amine oxidoreductase family protein 1.2e-9 ●○○○○ -0.13 -0.128471889963193
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2829  AIK81418.1  99 aa hypothetical protein 0.0015 ●○○○○ -0.13 -0.128407647149589
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2774  AIK81363.1  436 aa bacterial extracellular solute-binding family protein <1e-323 ●○○○○ -0.13 -0.128355960379211
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1986  AIK80592.1  122 aa hypothetical protein 6.8e-5 ●○○○○ -0.13 -0.128260454016837
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2984  AIK81569.1  242 aa transcriptional regulatory, C terminal family protein <1e-323 ●○○○○ -0.13 -0.127721848575626
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2525  AIK81122.1  329 aa 4-hydroxythreonine-4-phosphate dehydrogenase 0.017 ●○○○○ -0.13 -0.127431779213196
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2403  AIK81000.1  114 aa lipo, PulS/OutS family protein 9.7e-5 ●○○○○ -0.13 -0.126518840752752
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2686  AIK81280.1  323 aa branched-chain amino acid transport system / permease component family protein 6.0e-11 ●○○○○ -0.12 -0.12370133669142
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2645  AIK81239.1  391 aa putative D-serine deaminase (D-serine dehydratase) protein 2.7e-6 ●○○○○ -0.12 -0.123037568394385
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3999  AIK82546.1  537 aa permease for cytosine/purines, uracil, thiamine,allantoin family protein 5.6e-13 ●○○○○ -0.12 -0.122758732332286
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1996  AIK80602.1  414 aa mechanosensitive ion channel family protein 1.1e-11 ●○○○○ -0.12 -0.121319695359731
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2085  AIK80690.1  264 aa traB family protein 0.0019 ●○○○○ -0.12 -0.121024960198609
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2443  AIK81040.1  264 aa S-adenosylmethionine decarboxylase proenzyme 5.0e-5 ●○○○○ -0.12 -0.119077237601348
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2736  AIK81326.1  173 aa hypothetical protein 2.1e-5 ●○○○○ -0.12 -0.118720191727879
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2463  AIK81060.1  401 aa type II secretion system (T2SS), F family protein <1e-323 ●○○○○ -0.12 -0.118211195567071
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5064  AIK83590.1  153 aa oxidoreductase molybdopterin binding domain protein 0.0077 ●○○○○ -0.12 -0.117136337291197
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3954  AIK82502.1  166 aa hypothetical protein 4.0e-5 ●○○○○ -0.12 -0.11549365797735
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4436  AIK82979.1  305 aa periplasmic solute binding family protein 3.6e-5 ●○○○○ -0.11 -0.114587284199955
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4605  AIK83139.1  308 aa mucB/RseB family protein 0.00023 ●○○○○ -0.11 -0.1141998727986
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2190  AIK80795.1  179 aa hypothetical protein 3.1e-5 ●○○○○ -0.11 -0.113908789991548
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2513  AIK81110.1  500 aa L-arabinose isomerase 4.3e-7 ●○○○○ -0.11 -0.112249779423253
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2081  AIK80686.1  305 aa SPFH domain / Band 7 family protein 1.1e-16 ●○○○○ -0.11 -0.112229801099386
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3328  AIK81885.1  207 aa 16S rRNA (guanine(527)-N(7))-methyltransferase GidB 7.6e-7 ●○○○○ -0.11 -0.111140505477702
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2563  AIK81160.1  174 aa GPR1/FUN34/yaaH family protein 2.3e-7 ●○○○○ -0.11 -0.109920597599873
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4371  AIK82914.1  473 aa sugar (and other) transporter family protein <1e-323 ●○○○○ -0.11 -0.107239198151579
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4443  AIK82986.1  445 aa lamB porin family protein <1e-323 ●○○○○ -0.1 -0.104365458087757
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2993  AIK81578.1  365 aa fimbrial family protein <1e-323 ●○○○○ -0.1 -0.101760512605911
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2710  AIK81300.1  177 aa blc outer membrane lipoprotein 0.00073 ●○○○○ -0.1 -0.100278746579926
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2239  AIK80844.1  382 aa penicillin-binding protein <1e-323 ●○○○○ -0.1 -0.100112835772286
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2823  AIK81412.1  384 aa lactonase, 7-bladed beta-propeller family protein <1e-323 ●○○○○ -0.1 -0.0993836772360958
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4400  AIK82943.1  348 aa M42 glutamyl aminopeptidase family protein <1e-323 ●○○○○ -0.1 -0.0992194470225671
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2805  AIK81394.1  324 aa fructosamine deglycase frlB <1e-323 ●○○○○ -0.1 -0.0989217346843636
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3578  AIK82133.1  1350 aa TPR repeat family protein <1e-323 ●○○○○ -0.1 -0.0986246014785958
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3705  AIK82260.1  257 aa hypothetical protein 5.0e-15 ●○○○○ -0.1 -0.0980851598742563
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2122  AIK80727.1  408 aa binding-protein-dependent transport system innermembrane component family protein 1.5e-14 ●○○○○ -0.1 -0.0974251783639534
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2627  AIK81221.1  349 aa SIS domain protein 1.2e-14 ●○○○○ -0.1 -0.0973689493631157
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2308  AIK80912.1  325 aa taurine catabolism dioxygenase TauD, TfdA familyprotein 3.7e-9 ●○○○○ -0.1 -0.0973156962348697
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3051  AIK81636.1  396 aa malE 1.0e-10 ●○○○○ -0.1 -0.0968809782428101
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4168  AIK82714.1  486 aa 3-octaprenyl-4-hydroxybenzoate carboxy-lyase family protein <1e-323 ●○○○○ -0.1 -0.0952753372400243
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4354  AIK82897.1  366 aa 23S rRNA 2'-O-ribose C2498 methyltransferase 0.029 ●○○○○ -0.09 -0.094804328486226
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2804  AIK81393.1  277 aa pfkB carbohydrate kinase family protein <1e-323 ●○○○○ -0.09 -0.0947550197241692
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1508  AIK80128.1  405 aa integral membrane, PqiA family protein 2.6e-6 ●○○○○ -0.09 -0.0940356652067978
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2049  AIK80655.1  505 aa lysine--tRNA ligase 2.2e-16 ●○○○○ -0.09 -0.0934564222544082
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1848  AIK80454.1  292 aa transporter associated domain protein 0.0018 ●○○○○ -0.09 -0.0925658866540386
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3554  AIK82110.1  323 aa glyoxylate/hydroxypyruvate reductase B 2.3e-10 ●○○○○ -0.09 -0.0924231117273065
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4831  AIK83358.1  219 aa HAD hydrolase, IA, variant 3 family protein 0.012 ●○○○○ -0.09 -0.0916108247903955
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1941  AIK80546.1  320 aa hypothetical protein <1e-323 ●○○○○ -0.09 -0.0911933585529544
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3593  AIK82148.1  309 aa ketodeoxygluconokinase <1e-323 ●○○○○ -0.09 -0.0896222751184185
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2597  AIK81194.1  357 aa patatin-like phospholipase family protein 0.00013 ●○○○○ -0.09 -0.0895169685514619
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2155  AIK80760.1  432 aa trigger factor <1e-323 ●○○○○ -0.09 -0.0889899876288469
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3802  AIK82352.1  1036 aa acrB RND-type permease <1e-323 ●○○○○ -0.09 -0.0889567752052008
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3052  AIK81637.1  496 aa malF 0.00074 ●○○○○ -0.09 -0.0887890813588676
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2977  AIK81562.1  761 aa HAMP domain protein 7.0e-7 ●○○○○ -0.09 -0.08847478557225
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3099  AIK81680.1  211 aa thiamine-phosphate pyrophosphorylase <1e-323 ●○○○○ -0.09 -0.0882943590375577
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3677  AIK82232.1  815 aa glgP <1e-323 ●○○○○ -0.09 -0.0877587267349023
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2657  AIK81251.1  452 aa 4-hydroxyphenylacetate permease <1e-323 ●○○○○ -0.09 -0.0858310602885524
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3498  AIK82054.1  329 aa glycosyl transferase 2 family protein <1e-323 ●○○○○ -0.08 -0.0844681052045736
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3990  AIK82538.1  204 aa bacterial regulatory, luxR family protein 0.016 ●○○○○ -0.08 -0.08444167241047
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3730  AIK82284.1  406 aa argD 2.6e-13 ●○○○○ -0.08 -0.0841842210889648
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