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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Mycobacterium avium subsp. paratuberculosis K10  MAP_2082  AAS04399.1  Q73Y75  479 aa hypothetical protein 0.044 ○○○○○ 1.47 1.47310773190916
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2709  NP_232336.1  Q9KNM3  rpoZ  90 aa DNA-directed RNA polymerase subunit omega 0.00022 ○○○○○ 1.47 1.47315093520149
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4650  WP_000155057.1  E8XBK6  treC  550 aa alpha,alpha-phosphotrehalase 0.0033 ○○○○○ 1.47 1.47378074416914
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1349  WP_000175668.1  E8XGF1  ydiu  480 aa YdiU family protein 0.0016 ○○○○○ 1.47 1.47415981639282
Acinetobacter baumannii ATCC 17978  A1S_1951  ABO12378.2  480 aa hypothetical protein 7.0e-10 ○○○○○ 1.47 1.4746191119474
Acinetobacter baumannii ATCC 17978  A1S_3197  ABO13590.1  350 aa putative penicillin binding protein (PonA) 2.6e-10 ○○○○○ 1.47 1.47462740424841
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4352  WP_000373966.1  E8XLB2  nudC  257 aa NAD(+) diphosphatase 0.0036 ○○○○○ 1.48 1.47683276406316
Porphyromonas gingivalis ATCC 33277  PGN_1361  WP_012458217.1  B2RKI5  67 aa hypothetical protein <1e-323 ○○○○○ 1.48 1.47951576260544
Mycobacterium avium subsp. paratuberculosis K10  MAP_1463  AAS03780.1  Q73ZY8  552 aa hypothetical protein 0.044 ○○○○○ 1.48 1.47979946315014
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2150  AIK80755.1  624 aa surA N-terminal domain protein 1.0e-15 ○○○○○ 1.48 1.47983570691488
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1120  AIK79743.1  515 aa hypothetical protein <1e-323 ○○○○○ 1.48 1.47997041556818
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1507  CBW17601.1  A0A0H3NGS6  narU  462 aa nitrite extrusion protein 0.0011 ○○○○○ 1.48 1.48008457267505
Mycobacterium avium subsp. paratuberculosis K10  MAP_0660  AAS02977.1  Q743C5  357 aa hypothetical protein 0.044 ○○○○○ 1.48 1.48050366511478
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1407  CBW17502.1  A0A0H3NCX1  ydgI  460 aa hypothetical amino acid permease 0.00091 ○○○○○ 1.48 1.48086988867108
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1429  AIK80050.1  375 aa hypothetical protein <1e-323 ○○○○○ 1.48 1.48117253120373
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2106  AIK80711.1  1048 aa acrB RND-type permease <1e-323 ○○○○○ 1.48 1.4825228680304
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1741  WP_000763492.1  E8XKU1  trpD  531 aa bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD 0.0066 ○○○○○ 1.48 1.48374459218948
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4559  WP_000460338.1  E8XAN8  hflX  426 aa GTPase HflX 0.0022 ○○○○○ 1.48 1.48396869726479
Mycobacterium avium subsp. paratuberculosis K10  MAP_1769c  AAS04086.1  Q73Z34  442 aa hypothetical protein 0.043 ○○○○○ 1.48 1.48462136859913
Mycobacterium avium subsp. paratuberculosis K10  MAP_4215c  AAS06765.1  Q73S61  mmsA  506 aa MmsA 0.043 ○○○○○ 1.48 1.4846309708931
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0214  WP_000964234.1  E8XI03  yads  207 aa TRIC cation channel family protein 0.0025 ○○○○○ 1.48 1.48496267499115
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3375  AIK81932.1  89 aa hypothetical protein 2.3e-10 ○○○○○ 1.49 1.48512267242665
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1186  AIK79809.1  145 aa putative oxidoreductase 1.5e-6 ○○○○○ 1.49 1.48596742405973
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1023  NP_230668.1  Q9KT82  296 aa hypothetical protein 1.1e-6 ○○○○○ 1.49 1.48597919978938
Acinetobacter baumannii ATCC 17978  A1S_2760  ABO13173.2  303 aa geranyltranstransferase 4.0e-10 ○○○○○ 1.49 1.48641538152399
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0538  WP_001096865.1  E8X8A4  gcl  593 aa glyoxylate carboligase 0.0019 ○○○○○ 1.49 1.48665372523421
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0278  WP_000145244.1  E8XIT1  331 aa type VI secretion system baseplate subunit TssG 0.00046 ○○○○○ 1.49 1.48669471266799
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1095  AIK79718.1  799 aa hypothetical protein <1e-323 ○○○○○ 1.49 1.48679199332373
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0414  NP_230068.1  Q9KUV0  1252 aa hypothetical protein 0.0018 ○○○○○ 1.49 1.4880491330391
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2781  WP_000210995.1  E8XID5  302 aa SMP-30/gluconolactonase/LRE family protein 0.0025 ○○○○○ 1.49 1.4882371776213
Mycobacterium avium subsp. paratuberculosis K10  MAP_1925  AAS04242.1  Q73YN0  fadD15  600 aa FadD15 0.043 ○○○○○ 1.49 1.48859116478903
Mycobacterium avium subsp. paratuberculosis K10  MAP_3284c  AAS05834.1  Q73UT2  fadD29  1115 aa FadD29 0.043 ○○○○○ 1.49 1.48880903653351
Escherichia coli M12  CO715_19710  ATI07746.1  834 aa copper-exporting P-type ATPase CopA 9.1e-8 ○○○○○ 1.49 1.48919711492284
Escherichia coli M12  CO715_16955  ATI07255.1  156 aa hydrogenase 3 maturation endopeptidase HyCI 0.013 ○○○○○ 1.49 1.48982305296559
Mycobacterium avium subsp. paratuberculosis K10  MAP_1801c  AAS04118.1  Q73Z02  538 aa hypothetical protein 0.043 ○○○○○ 1.49 1.49027832381896
Mycobacterium avium subsp. paratuberculosis K10  MAP_3765  AAS06315.1  Q73TF3  538 aa hypothetical protein 0.043 ○○○○○ 1.49 1.49138090005708
Mycobacterium avium subsp. paratuberculosis K10  MAP_2582c  AAS04899.1  Q73WS8  763 aa hypothetical protein 0.043 ○○○○○ 1.49 1.49311831548622
Mycobacterium avium subsp. paratuberculosis K10  MAP_3523c  AAS06073.1  Q73U45  oxcA  594 aa OxcA 0.043 ○○○○○ 1.49 1.4935241603032
Escherichia coli M12  CO715_02360  ATI04677.1  235 aa lipopolysaccharide core heptose(II) kinase RfaY 1.7e-23 ○○○○○ 1.49 1.49462191129331
Mycobacterium avium subsp. paratuberculosis K10  MAP_2791  AAS05108.1  Q73W69  ribD  254 aa RibD 0.043 ○○○○○ 1.49 1.4947377056449
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3141  CBW19240.1  A0A0H3NG12  151 aa conserved hypothetical protein 0.0097 ○○○○○ 1.5 1.49642853028344
Escherichia coli M12  CO715_12270  ATI06415.1  78 aa hypothetical protein 4.5e-12 ○○○○○ 1.5 1.49754295549279
Escherichia coli M12  CO715_00760  ATI04393.1  165 aa radical SAM protein 1.7e-23 ○○○○○ 1.5 1.49796024752129
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1874  AIK80480.1  262 aa carbon-nitrogen hydrolase family protein <1e-323 ○○○○○ 1.5 1.49887991656652
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1631  AIK80251.1  150 aa phage head completion family protein 1.4e-7 ○○○○○ 1.5 1.4996283379498
Escherichia coli M12  CO715_03085  ATI04809.1  130 aa hypothetical protein 0.031 ○○○○○ 1.5 1.49983806164953
Escherichia coli M12  CO715_02105  ATI04631.1  296 aa maltose ABC transporter permease MalG 2.1e-7 ○○○○○ 1.5 1.50004670766378
Mycobacterium avium subsp. paratuberculosis K10  MAP_3181  AAS05729.1  Q73V35  551 aa hypothetical protein 0.042 ○○○○○ 1.5 1.50041126288464
Mycobacterium avium subsp. paratuberculosis K10  MAP_2638c  AAS04955.1  Q73WM2  mcr  360 aa Mcr 0.042 ○○○○○ 1.5 1.50058412321014
Escherichia coli M12  CO715_15500  ATI06993.1  443 aa HslU--HslV peptidase ATPase subunit 0.0017 ○○○○○ 1.5 1.50129858374927
Mycobacterium avium subsp. paratuberculosis K10  MAP_2579c  AAS04896.1  Q73WT1  444 aa hypothetical protein 0.042 ○○○○○ 1.5 1.50181324586457
Mycobacterium avium subsp. paratuberculosis K10  MAP_1707  AAS04024.1  Q73Z96  236 aa hypothetical protein 0.042 ○○○○○ 1.5 1.50217191270532
Mycobacterium avium subsp. paratuberculosis K10  MAP_1357  AAS03674.1  Q740J3  322 aa hypothetical protein 0.042 ○○○○○ 1.5 1.50270122636219
Acinetobacter baumannii ATCC 17978  A1S_1829  ABO12256.2  268 aa hypothetical protein 0.00061 ○○○○○ 1.5 1.50378356242933
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1327  AIK79950.1  488 aa HAMP domain protein 1.6e-7 ○○○○○ 1.51 1.50514285177178
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0501  NP_232892.1  Q9KM82  131 aa hypothetical protein 0.03 ○○○○○ 1.51 1.50665314074413
Mycobacterium avium subsp. paratuberculosis K10  MAP_1672  AAS03989.1  Q73ZD1  522 aa hypothetical protein 0.042 ○○○○○ 1.51 1.50688110574834
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0003  NP_232404.1  Q9KNG1  204 aa hypothetical protein 0.038 ○○○○○ 1.51 1.50701374793479
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3045  WP_000971655.1  E8XL33  175 aa N-acetyltransferase 0.0026 ○○○○○ 1.51 1.50786707886618
Escherichia coli M12  CO715_11475  ATI06270.1  374 aa ring-hydroxylating oxygenase subunit alpha 0.00021 ○○○○○ 1.51 1.50839254823373
Mycobacterium avium subsp. paratuberculosis K10  MAP_0366  AAS02683.1  Q744H5  selD  305 aa SelD 0.042 ○○○○○ 1.51 1.50888648882489
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1399  NP_231042.1  Q9KS61  cheR2  288 aa chemotaxis protein CheR 0.011 ○○○○○ 1.51 1.50944929115637
Mycobacterium avium subsp. paratuberculosis K10  MAP_3700c  AAS06250.1  Q73TL8  104 aa hypothetical protein 0.042 ○○○○○ 1.51 1.50984759607382
Mycobacterium avium subsp. paratuberculosis K10  MAP_3844  AAS06394.1  Q73T75  1425 aa hypothetical protein 0.042 ○○○○○ 1.51 1.51004189460114
Mycobacterium avium subsp. paratuberculosis K10  MAP_3854  AAS06404.1  Q73T65  424 aa hypothetical protein 0.042 ○○○○○ 1.51 1.5144737106119
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4224  WP_000009249.1  E8XKA9  382 aa lactaldehyde reductase 0.0029 ○○○○○ 1.51 1.51459647536571
Mycobacterium avium subsp. paratuberculosis K10  MAP_1824c  AAS04141.1  Q73T65  424 aa hypothetical protein 0.041 ○○○○○ 1.52 1.51527354782479
Mycobacterium avium subsp. paratuberculosis K10  MAP_1624  AAS03941.1  Q73ZH9  101 aa hypothetical protein 0.041 ○○○○○ 1.52 1.5155292482512
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1769  AIK80389.1  121 aa ybgS-like family protein <1e-323 ○○○○○ 1.52 1.51636345658126
Escherichia coli M12  CO715_16030  ATI07086.1  283 aa pantoate--beta-alanine ligase 1.1e-10 ○○○○○ 1.52 1.51945078698892
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1248  AIK79871.1  46 aa hypothetical protein 9.1e-13 ○○○○○ 1.52 1.52058882469244
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1410  AIK80033.1  245 aa putative hydrolase ycdX <1e-323 ○○○○○ 1.52 1.52075629523565
Mycobacterium avium subsp. paratuberculosis K10  MAP_0227c  AAS02544.1  Q745M4  171 aa hypothetical protein 0.041 ○○○○○ 1.52 1.52090292837584
Escherichia coli M12  CO715_15370  ATI06972.1  206 aa superoxide dismutase [Mn] 1.4e-7 ○○○○○ 1.52 1.52111995510291
Mycobacterium avium subsp. paratuberculosis K10  MAP_3438c  AAS05988.1  Q73UD0  add  366 aa Add 0.041 ○○○○○ 1.52 1.52277085730698
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2823  WP_001207652.1  E8XIH7  171 aa phage major tail tube protein 2.4e-7 ○○○○○ 1.52 1.52356700155418
Escherichia coli M12  CO715_11835  ATI06335.1  535 aa ABC transporter substrate-binding protein 6.2e-45 ○○○○○ 1.52 1.5236237072739
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1217  AIK79840.1  253 aa 2-deoxy-D-gluconate 3-dehydrogenase <1e-323 ○○○○○ 1.53 1.53028823608142
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1101  NP_233481.1  Q9KKK3  486 aa ABC transporter ATP-binding protein 0.015 ○○○○○ 1.53 1.53029672851593
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4029  WP_001527038.1  E8XHT8  yieF  194 aa NAD(P)H-dependent oxidoreductase 0.0072 ○○○○○ 1.53 1.53094658320206
Porphyromonas gingivalis ATCC 33277  PGN_0184  WP_012457310.1  B2RH58  fimD  670 aa hypothetical protein 0.011 ○○○○○ 1.53 1.53167023208631
Mycobacterium avium subsp. paratuberculosis K10  MAP_1699  AAS04016.1  Q73ZA4  thiI  409 aa ThiI 0.04 ○○○○○ 1.53 1.53191801634854
Mycobacterium avium subsp. paratuberculosis K10  MAP_3319  AAS05869.1  Q73UP7  321 aa hypothetical protein 0.04 ○○○○○ 1.53 1.53324650619191
Mycobacterium avium subsp. paratuberculosis K10  MAP_4171  AAS06721.1  Q73SA4  atsA  789 aa AtsA 0.04 ○○○○○ 1.53 1.53386162745834
Mycobacterium avium subsp. paratuberculosis K10  MAP_0689c  AAS03006.1  Q742Z6  narL  217 aa NarL_1 0.04 ○○○○○ 1.53 1.53399094385664
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1464  AIK80085.1  374 aa putative 2Fe-2S cluster-containing protein <1e-323 ○○○○○ 1.53 1.5340906948908
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3664  WP_000660723.1  E8XEK0  yrfH  133 aa ribosome-associated heat shock protein Hsp15 0.00045 ○○○○○ 1.54 1.53558673191226
Escherichia coli M12  CO715_01025  ATI04438.1  319 aa phosphate ABC transporter permease 0.037 ○○○○○ 1.54 1.53572517610034
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0848  NP_233234.1  Q9KL98  326 aa diguanylate cyclase 0.0029 ○○○○○ 1.54 1.53940041844335
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1396  AIK80020.1  354 aa rhodanese-like domain protein 1.3e-5 ○○○○○ 1.54 1.53961348755903
Mycobacterium avium subsp. paratuberculosis K10  MAP_2040c  AAS04357.1  Q73YB6  118 aa hypothetical protein 0.04 ○○○○○ 1.54 1.53965505342765
Mycobacterium avium subsp. paratuberculosis K10  MAP_0537  AAS02854.1  Q743Q4  381 aa hypothetical protein 0.04 ○○○○○ 1.54 1.54125970681413
Escherichia coli M12  CO715_13045  ATI06552.1  163 aa PTS IIA-like nitrogen regulatory protein PtsN 0.024 ○○○○○ 1.54 1.54219320254205
Streptococcus pyogenes M1 5448  SP5448_06810  WP_010922101.1  94 aa chorismate mutase 0.034 ○○○○○ 1.54 1.54372985757304
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3623  WP_000398133.1  E8XE02  kefB  601 aa glutathione-regulated potassium-efflux system protein KefB 0.0014 ○○○○○ 1.54 1.54384205111393
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1860  WP_001537930.1  E8X8K9  yobF  47 aa DUF2627 domain-containing protein 0.00017 ○○○○○ 1.54 1.54409137618942
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1519  CBW17613.1  A0A0H3NLE7  yncC  221 aa hypothetical regulatory protein 0.00041 ○○○○○ 1.54 1.54492116644888
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1442  WP_001237787.1  E8XHC8  gloA  135 aa lactoylglutathione lyase 0.0023 ○○○○○ 1.55 1.54658951317654
Streptococcus pyogenes M1 5448  SP5448_08180  WP_002985989.1  197 aa HD domain-containing protein 0.025 ○○○○○ 1.55 1.54661386706724
Mycobacterium avium subsp. paratuberculosis K10  MAP_1706  AAS04023.1  Q73Z97  145 aa hypothetical protein 0.04 ○○○○○ 1.55 1.54665879440407
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