Bacterial taxon 262316 Locus MAP_1420 Protein AAS03737.1

hypothetical protein

Mycobacterium avium subsp. paratuberculosis K10

Length 6,384 aa, Gene n/a, UniProt Q740D1

					>AAS03737.1|Mycobacterium avium subsp. paratuberculosis K10|hypothetical protein
MKRGDRAYPVTRGQLDIWLAEQTGHLDVAWQLGVLVRIDGAIDPALLHQTMRHVVGEAESLRASFFEADGQVFQKAVEYSDVDLTFYDLSGSSDPEREVREMTASIQRTPMPLTGPMIKFALFRTGSAEYYWFTTCHHIAIDGMGIALVGRRIAAVYTALASGKPIPPAFFGSLQDLVGGELEYEASAKFLEDKDYWLAHRPGDGTAGHPPRPADDGRDPYSPSPPVQLDESVIGSVKELSKALGIRRSSVLTAACALLVRGWCADGSDEVVLDFPVSRRVDPKSKTHPGMLAGVVPLVLHAPAAATFADFCRHVDQRSREALRHQQFPTRTLDGEGDFSGPRQAPNRVVVNFVPARLTLSLADVPATATYTSFGPVGHFGLFFLGFGDQQFLSTVGTGQPLANFDATDLAERLQRILAAMAADPARLLSSLDVLRDPEHAQLEALGNTAVLTRTPGPAVSVPELFATQVARAPQDVALVCEGRSLTYRQLDEASNRLAHLLAGLGAGPGQSVALLFSRSAEAVASILAVLKTGAAYLPIDPAAPETRIGFMLADAKPVAALSTAELAGRLEGHGMTVIDVNDPRIQDRPATALPVPAADGVAYVIYTSGTTGVPKGVAVTHRNVTQLLGSLDAGLPPAGVWSQCHSYAFDVSVWEIFGALLRGGRLVVVPEDVTRAPEELHDVLVNEQVSVLTQTPSAVAMLSPQGLESVSLVVVGEACPAEVVDRWSPGRVMVNAYGPTETTMCVAISAPLAPGMGSPPIGVPVDGAGLFVLDAWLRPVPPGVVGELYVGGAGVACGYWRRGGLTASWFVACPFGAPGARMYRTGDLVCWRSDGQLDYRGRADEQVKVRGYRIELGEVQAALAALDDVDQAVVIAREDRPGGKRLVGYITGTADPAEVRTALAQRLPVYMVPAAVVALDAIPLTPNGKLDTRALPTPEYTGSRYRAPSNAVEETVAGIYAHVLGVERVGVDDSFFDLGGDSISALQVVARARAAGLTCRPRDVFVEQTVARLARVVGSGDRAAEVADEGVGPVPPTPIMRWLQAAERAGGATDQFNQTVLVQAPAGVTETEVAIVLQALVDRHAMLRLRVTDDGADGWSFEVPEAGSVQARDCLRSVDALSDEALLAARARLNPAAGTMLAALWVEATGQLAVIIHHLAVDAVSWWILLEDLNIAWALHRAGQPVELAPAGTSFARWARLLDEHARDPEVVGQLDRWKTVTSTPAALPAPRPDVDTYASAGRLSVELDAETTAMLLGEVPAAFHAGIHDILLIAFGLAWTEFLGEPGAPIGIDVEGHGRHEELGADIDLSRTVGWFTAKYPVSLDVAGLRWPQVAAGDPALGPVLKRAKEQLRTLPEPLTYGLLRYLNTDVDLAGADPPIAFNYLGRQGAASDSAADGWRISQDMSLLGAAAAVPMPLMHAVELNAGTIDTGAGPHLHAEWTWAPSVLGAEQITRVSRLWFEALAGVCAHVRSGGGGGLTPSDIAPARLTQQQIDELQSRHRIADILPLTPLQQGLLFHSSTAQGNDGMDDMYAVQLDFTLTGPLDADRLREAVRTVVHRHPHLAALFCDQYDEPVQIIPADPAVEWRYVELDGTGAADADDLIEQLCAAERAAVADLAGQPVFRTALVRTGGDRHRFVLTSHHILLDGWSLPILLREIFAGYYGQRLPAAGSYRAFLTWLAERDLDAARRAWGEVLSGFDTPTLVAPEGRLGQGRRGFEKSCVPEQTTRALGELARSCHTTLSTVLQAAWAVVLTSLTGRHDVVFGTPRSRVGQLEVDDAEQMVGLLINTVPVRAEITATTTTAQLLAQLQNSHNDTLEHQHLALNEIHRVTGHDQLFDTLFVYENYPIDSGMTLGADGLAIAEFTNREYNHYPLTVEALPGPELGLHIEFDTDVFDTASIESLVQRLQRVLVAMSTDPDRRLSSLDLLDRGERELVLSTMSGAGVSAPIGVAPQLLAAAVAADPDAPAIVDGARELSYRELDDWSTRLARKLIQHGVGPEHAAGVAIERCAELVVAWWAVTKVGGVYAPVNLDHPVERIASVLDTVNAVCVLTCGTDEVAGAGPRPILRIDGLDLSGHSTEPITDADRRSPLRADDTAYLIFTSGSTGVPKGVAVSHTGLLGWAAAQRELFGLGADARVLMVASPTFDASVGELLLAAGSGAALIVAPPQVYAGEALTALLHNQRVGTAILTPTVISTLDRGRLDGLHTLVAVGEACLPELVDGWAPGRQMFNGYGPSETTIWVTCARLTAGHPVRIGAPIPGVCARVLDGWLKPVPVGVVGELYLSGPALGHGYLGRVDLTAERFVANPFGGPGERMYRTGDLVRWTPEGTLDYLGRADNQIKLRGQRIELGEIENTLLACPQVTQAAVTVQDSAAGSQLVAYVTLDHGPSDADVRHDTDDADDVAQWRHLYDDLYGADLAATFGEDFRGWNSSYTGEPIPLQEMAEWRSATVDRIMSLRPRRVLEIGAGSGLLLSQIAPRCDRYVATDFSAVAIDNLARSMEQLQLPWRDRVELLTQPAHVTDGLPPGHFDTIVINSVVQYFPNAGYLADVIDNALELLAPGGSLFIGDVRNHALQGAFQTGIALARGGGADAAEIRQRVRHAMLGETELLLAPEFFTNWADSRPAAAGLDIQLKRGLSDNELNRYRYDVVIHKAPAPVRSVAAAPTWSWTDCTDCAGLRDQLAARRPAVVRVTDIPQAGVIDDVRVEAALAAGLPVADALAAAGSDTAAAVAEELHRVGEATGYRVAVTWGAQPGTLSAVFVQDGDQAAEPLTDLYLPPAGARQRTRHANDPRANTKIAQVRERLNAWLPEYMVPTHIVALDEFPMTTSGKLDRKALPAPDYQDADRYRAPSTAVEEILVGIYGQVLGLERVGVDDSFFDLGGDSLSAMRLIAAVNASLNTDLGVRTVFEAPTAAELALRVGSEADRPEPLVAGERPAVIPLSFAQTRLWFIDQFQGPSPMYNITVALRLSGRLDADALRAALADVVARHESLRTVFATADGTPQQVVIPADRIGFACDVVDARGWPEDRLREAMSAAARYTFDLSAESPLHTELFARGDDEHVLVVAVHHIAADGWSITPFARDLGVAYASRCAGRDPDWAPLPVQYADYTLWQRAHLGDVDDPGSRIAAQLDFWTDALAGLPERLQLPTDRPYPAVADHRGARLAVDWPAELQQQLRRVAREHDATSFMVVQAAFAALLAKVSASSDVAVGFPIAGRPEPVLDELIGFFVNTLVLRVDLNELGGDPTFAELLAQVRRRSLAAFEHQDVPFELLVERLNPTRSMSHHPLVQVLLGWENFPGEVTAPAAGLALGDLQVTPMPLHTNTARMDLTFSLAERFTESGQRAGIAVTAEYRTDVFDGRTVEGLIERLQRLLTAVTADPQRRLSAVDLLDANEHARLEKWGNTAVLARPATPVSVPARFAAQAARTPDAVALTCDGRSMTYRELDEAANRLAHFMIHHGAGPGERVALLFPRSAEAIVAILAALKSGAAYLPIDPALPAARVEFMLTDAAPIVAVTTAALAERLHGFDLTVIDVADPAVATQPATAPPVPDPDDVAHIIYTSGTTGVPKGVAVTQYNVAQLFDDLRIGIELSPRQVWTQFHSYAFDFSVWEIWGALLHGGRLVVVPETVSRSPNEFHDLLVREHVTVLTQTPSAVGLLRTDGLDGTALVIGAEPCPPELVDRWAPGRTMVNVYGPTETTMWACKSAPLTAGSGFPPIGAPVTRAAFFVLDDWLRPVPPGVVGELYLAGDGVGVGYWRRPGLTAARFLACPFGEPGTRMYRTGDLVCWGPDGQLRYLGRADEQVKVRGYRIELGEIQAALSALDGVEQAVVVAREDNPGDKRLVGYVTGSVAPAKARAALAERLPAYMVPAAVVVLDSLPMTVNGKLDTRALPAPDYWHTGGYRAPESPTEEILAGIYAEVLGVQRVGVDDSFFDLGGDSLTTMRLITAINSALDTDLPVRTVFEAPTIAQLAPRIAQSAGGLAPLVAAGRPDVVPLSFAQNRLWFIDQSQGPSPLYNMAAALRLRGRLDAGALGAALGDVVARHESLRTVFPSHQGTPRQLVVPAERAEFGWDVIDATDWPADRLDDAVQDVTRHTFDLAAEIPIRAKLFAVSEDEHVLVIVVHHIAADGMSLTPLGVDLSQAYASRCAGHAPGWADLPVQYCDYTLWQRAQFGDLNDPDSRIGTQLAYWEDALAGMPERLALPTDRPYPAAADQRGDSVAVDWPAELQQQVRRIAREHNATSFMVVQAALAVLLSKIGASSDVAVGFPIAGRRDPALDQLVGFFVNTLVLRIDLTGDPSFAELLALVQARSLAAFEHQDVPFEVLVERLNPTRSLTHHPLVQVMLAWQNFAGHDDPAAALALGDLDVTSVPVHDQSARMDLVFSLAERWNPDGEFAGIGGRVEFRTDVFDAATIETLIERLRRVLEAMTGDPGRPLSAVDLLDDAERAYLEEVGNTAILTRPASGRVSVPELFATQVARVPETVALVCDDLSVTYRQLDEASNRLAHRLAAAGAGPGQTVALLFSRSAEAVAAILAVLKTGAAYLPIDPSAPQTRVEFMLGDAEPIAAVTTAELAQRLAGRPVTVVDVDDPGIDTLPNTALPLPDPDGIAYLIYTSGTTGAPKGVAVTHHNVTQLLGSLDAGLPSPGVWSQCHSLAFDVSVWEIFGALLRGGRVVVMPEAVARSPHDLHDALIARHVTVLTQTPSAVAMLSPQGLESVSLVLAGEACPPEVVDQWAPGRVMVNGYGPTETSMCVSISAPLTAGSGIPPIGSPVDGAALFVLDESLRPVPPGVVGELYVAGSGVAAGYLGRPSLTAARFVACPFGAPGARMYRTGDLVRWRADGQLDYLGRADEQVKVRGYRIELGEIQAALSALDGVEQAVVVAREDNPGDKRLVGYITGTADPAEARARLGERLPAYMVPAAVLGLDAIPLTPNGKLDARALPAPDYAAGEYRAPESPTEEILAGIYAEVLGVQRVGVDDSFFDLGGDSISAMRLIAAVNAALNADLPVRTVFEAPTVAALAPRIGEGGSGLEPLTAGERPTVVPLSFAQNRLWFLDQLQGPSPVYNMAAALRLDGPLDTEALGAALGDVVARHESLRTLFAAPEGRPQQVVLPAERADFGWEVVDASGWSADQLDEAIGATARYTFDLAAQIPLRAELFRLRDDRHVLVAVVHHIAADGMSITPLVRDLGAAYARRCDGRGPDWTPLPVQYVDYTLWQRAQFGELADSGSRIAAQLAYWQDALAGMPERLALPTDRPYPLVADQRGATVEIDWPAELQQRIGDVAHRHNATSFMVIQTALTVLLAKLGANPDVAVGFPIAGRRDPALDDLVGFFVNTLVLRVDAAGDPSFTELLARVRTRSLEAFEHQDVPFEVLVERLNPTRSLTHHPLVQVMLAWQNFAGQDTGPAAGLSLGDVEITPIPVDTHTARMDLTFSVGERWCESGEPGGIGGTVEFRTDVFDPDSIQTLIGRLRRVLEAMTDDPTQSVWSVDLLDAGEHARLDTLGNRAALTGPPPRFDSLPTLFAEQAARTPDAVALVCGGRRMTYRELDEAANRVAHLLRVRGAGPGHTVALLFSRSAEAIVAILGVLKSGAAYLPIDPALPGERIGFMLADAAPMVAISTAELAPRLHGQHDVPVIDVHDPAIEAAPSSALPPPGADDIAYLIYTSGTTGVPKGVAVSHRNVTQLLTADSGLPREGVWSQWHSLAFDVSVWEIFGALLHGGRLVVIPDSVVRSPDDFHALLLDEQVSVLSQTPSAAGTLSPEGLEDLTLVVAGEACPAELVDRWAPGRTMINAYGPTEATVYTAISAPLQPGSPAGVPIGFPVPGAGLFVLDESLRPVPPGVVGELYVGGAGVACGYWRRGGLTASWFVACPFGAPGARMYRTGDLVCWRSDGQLDYRGRADEQVKVRGYRIELGEVQAALAGLDDVEQAVVIAREDRPGGKRLVGYITGTADPAEVRTALAQRLPVYMVPAAVVALDAIPLTPNGKLDTRALPTPEYTGSRYRAPSNAVEETVAGIYAHVLGVERVGVDDSFFDLGGDSISAMRVITAINASLGVELAVRTLFEAPTVASLSWRAQTDTARGGQAEEIVPVQTLKEGTGAPLFCIHAAGGLSWSYQVLGNHLDCPIIGIQQAEPQHAAPRSIREMAQSYADRIQETYPDGPYHLVGWSFGGVVAHELAIELQRRGCAIARLVLLDAQPGLDGSVTAPDAALAEQHMMEEALRSHLAAADHDQPHAHRQFNQLVREAGAEGMSRHKRLFDVLFGNARNNIERSKIHEPGVFLGDVTIFSAVRDHEDRSAFLAENWRPYVAGDIVIHEIDCTHDEILNADVVDSYGQRLGQLLGAQRRRELTPPQRFGADPGDDEPPVR
				

Host	Tissue	Tissue Ontology	Time Post Infection	Transposon Insertion Site	Raw Fitness Score	p-Value	Fitness z-Score	Precise fitness z-Score	Reference
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,550,472	7.41	0.014	○○○○○ 2.11	2.1051533114434844	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,543,482	7.47	0.014	○○○○○ 2.12	2.124763735264601	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,535,253	7.81	0.011	○○○○○ 2.23	2.23497762321305	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,549,824	8.64	0.0056	○○○○○ 2.51	2.5078864033888584	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,536,975	-1.83	0.085	●○○○○ -0.93	-0.9250267115100449	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,543,083	-1.63	0.09	●○○○○ -0.86	-0.8589518502023819	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,543,638	-1.46	0.095	●○○○○ -0.8	-0.8012338327990904	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,543,131	-1.4	0.096	●○○○○ -0.78	-0.782045294982473	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,534,619	-1.39	0.096	●○○○○ -0.78	-0.7799021945722783	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,550,868	-1.29	0.099	●○○○○ -0.75	-0.7459050892977178	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,536,087	-1.14	0.1	●○○○○ -0.7	-0.6976308673719357	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,534,842	-0.73	0.11	●○○○○ -0.56	-0.5631389265838413	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,534,890	-0.71	0.11	●○○○○ -0.56	-0.5570791347401788	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,550,061	-0.71	0.11	●○○○○ -0.56	-0.5570503694637331	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,550,109	-0.71	0.11	●○○○○ -0.56	-0.5557960188635932	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,549,410	-0.33	0.12	●○○○○ -0.43	-0.43044760004503296	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,539,267	-0.23	0.12	●○○○○ -0.4	-0.39847075554096373	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,534,740	-0.14	0.12	●○○○○ -0.37	-0.3682007855273403	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,544,091	-0.1	0.12	●○○○○ -0.36	-0.35578608373697984	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,543,740	-0.04	0.12	●○○○○ -0.34	-0.3374341226457771	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,549,401	0.08	0.13	●○○○○ -0.3	-0.2969634397376437	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,551,342	0.4	0.13	●○○○○ -0.19	-0.19224758677467566	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,533,483	0.59	0.13	●○○○○ -0.13	-0.13121620984053212	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,550,322	0.59	0.13	●○○○○ -0.13	-0.12927110963012226	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,535,103	0.62	0.13	●○○○○ -0.12	-0.11956826423847666	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,549,959	0.76	0.13	●○○○○ -0.08	-0.07589267324769691	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,540,029	0.9	0.13	●○○○○ -0.03	-0.02799175905819105	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,533,033	0.93	0.13	●○○○○ -0.02	-0.020212413255383727	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,537,143	1.49	0.13	○○○○○ 0.17	0.16531543282004998	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,543,788	2.43	0.12	○○○○○ 0.47	0.47365586726818537	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,547,160	2.94	0.11	○○○○○ 0.64	0.638231433117086	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,532,607	3.18	0.1	○○○○○ 0.72	0.7183338096443092	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,541,277	3.36	0.097	○○○○○ 0.78	0.7767947407014048	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,547,991	3.69	0.088	○○○○○ 0.89	0.8858135234555624	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,546,899	3.85	0.084	○○○○○ 0.94	0.9364852572005224	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,544,001	4.48	0.068	○○○○○ 1.14	1.1444986677240738	24885784
Mouse (Mus musculus C57BL/6)	spleen	BTO:0001281	1 month	1,539,621	4.69	0.063	○○○○○ 1.21	1.2129503805214323	24885784

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