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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli CFT073  c1878  AAN80338.1  A0A0H2V9J4  ansP  516 aa L-asparagine permease n.s. ●○○○○ -0.47 -0.474423950373628
Streptococcus pyogenes M1 5448  SP5448_06595  WP_010922123.1  358 aa ABC transporter permease n.s. ●○○○○ -0.47 -0.474307719164584
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2200  CBW18296.1  A0A0H3NDL4  yejH  586 aa hypothetical helicase n.s. ●○○○○ -0.47 -0.474199372504066
Serratia marcescens Strain UMH9  BVG96_15235  ASL98900.1  308 aa LysR family transcriptional regulator n.s. ●○○○○ -0.47 -0.474145332631961
Streptococcus pyogenes M1 5448  SP5448_06485  WP_002990274.1  498 aa DUF2142 domain-containing protein n.s. ●○○○○ -0.47 -0.474115451864971
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4613  AIK83147.1  126 aa holo-[acyl-carrier-protein] synthase n.s. ●○○○○ -0.47 -0.473740801275973
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1372  CBW17468.1  A0A0H3NB27  sodCb  173 aa copper-zinc superoxide dismutase n.s. ●○○○○ -0.47 -0.473625426198947
Escherichia coli CFT073  c2572  AAN81027.1  A0A0H2VA15  wcaJ  464 aa Putative colanic biosynthesis UDP-glucose lipid carrier transferase n.s. ●○○○○ -0.47 -0.473612721932204
Mycobacterium avium subsp. paratuberculosis K10  MAP_0948  AAS03265.1  Q741Y9  569 aa hypothetical protein n.s. ●○○○○ -0.47 -0.473274875067935
Escherichia coli O157:H7 str. EDL933  Z0844  AAG55018.1  682 aa ATPase of high-affinity potassium transport system, B chain n.s. ●○○○○ -0.47 -0.473274645172778
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3618  WP_000091471.1  E8XDZ7  yheO  240 aa transcriptional regulator n.s. ●○○○○ -0.47 -0.472994669775728
Escherichia coli CFT073  c3386  AAN81831.1  A0A0H2VCJ3  514 aa Conserved hypothetical protein n.s. ●○○○○ -0.47 -0.472982957798582
Haemophilus influenzae Rd KW20  HI_0183  NP_438351.1  P44555  481 aa amino acid carrier protein n.s. ●○○○○ -0.47 -0.472542415681221
Mycobacterium avium subsp. paratuberculosis K10  MAP_0947c  AAS03264.1  Q741Z0  415 aa hypothetical protein n.s. ●○○○○ -0.47 -0.472523972106637
Escherichia coli O157:H7 str. EDL933  Z5621  AAG59222.1  90 aa orf, hypothetical protein n.s. ●○○○○ -0.47 -0.472412065936309
Vibrio parahaemolyticus RIMD 2210633  VPA_0645  BAC61988.1  Q87IG1  386 aa putative dihydrolipoamide acetyltransferase n.s. ●○○○○ -0.47 -0.472335442928297
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0214  CBW16316.1  A0A0H3NHI7  dapD  274 aa 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase n.s. ●○○○○ -0.47 -0.4723268081946
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0277  WP_009881964.1  A0A0H3PB28  436 aa MFS transporter n.s. ●○○○○ -0.47 -0.472301363562
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3409  WP_001118363.1  E8XC69  agaR  277 aa DeoR/GlpR transcriptional regulator n.s. ●○○○○ -0.47 -0.47212582976008
Vibrio parahaemolyticus RIMD 2210633  VP_0875  BAC59138.1  Q87RC2  94 aa conserved hypothetical protein n.s. ●○○○○ -0.47 -0.472120931757529
Escherichia coli CFT073  c0762  AAN79235.1  A0A0H2V5X0  385 aa Putative alcohol dehydrogenase n.s. ●○○○○ -0.47 -0.472094716231132
Haemophilus influenzae Rd KW20  HI_0467  NP_438628.3  P44726  287 aa hypothetical protein n.s. ●○○○○ -0.47 -0.471985328628544
Mycobacterium avium subsp. paratuberculosis K10  MAP_2472  AAS04789.1  Q73X38  362 aa hypothetical protein n.s. ●○○○○ -0.47 -0.471888825698172
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3003  CBW19102.1  A0A0H3NFQ7  STM3025  232 aa regulatory protein n.s. ●○○○○ -0.47 -0.471887268714511
Serratia marcescens Strain UMH9  BVG96_11525  ASL98214.1  267 aa protein of avirulence locus ImpE n.s. ●○○○○ -0.47 -0.471794837750895
Escherichia coli CFT073  c0764  AAN79237.1  A0A0H2V599  328 aa Putative pyridoxine phosphate biosynthetic protein n.s. ●○○○○ -0.47 -0.471620559797835
Mycobacterium avium subsp. paratuberculosis K10  MAP_1567  AAS03884.1  Q73ZN4  modB  258 aa ModB n.s. ●○○○○ -0.47 -0.47155101745044
Escherichia coli CFT073  c3395  AAN81840.1  A0A0H2VAD3  658 aa Hypothetical protein n.s. ●○○○○ -0.47 -0.471437192636484
Mycobacterium avium subsp. paratuberculosis K10  MAP_0744c  AAS03061.1  Q742U1  297 aa hypothetical protein n.s. ●○○○○ -0.47 -0.471157323980094
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1979  CBW18076.1  A0A0H3NEH1  157 aa conserved hypothetical protein n.s. ●○○○○ -0.47 -0.471042240893266
Escherichia coli CFT073  c3534  AAN81982.1  P0A8W6  yqgE  211 aa Protein yqgE n.s. ●○○○○ -0.47 -0.470786952787691
Mycobacterium avium subsp. paratuberculosis K10  MAP_2448  AAS04765.1  Q73X62  199 aa hypothetical protein n.s. ●○○○○ -0.47 -0.470757666510251
Streptococcus pyogenes M1 5448  SP5448_04680  WP_010922375.1  337 aa ATP-dependent 6-phosphofructokinase n.s. ●○○○○ -0.47 -0.470750774121745
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4310  WP_000971958.1  E8XL82  yijC  211 aa HTH-type transcriptional repressor FabR n.s. ●○○○○ -0.47 -0.470503725297515
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0195  CBW16297.1  A0A0H3N7Q7  fhuB  685 aa ferrichrome transport protein FhuB precursor n.s. ●○○○○ -0.47 -0.470286873239887
Vibrio parahaemolyticus RIMD 2210633  VP_0035  BAC58298.1  Q87TN4  ilvC  494 aa ketol-acid reductoisomerase n.s. ●○○○○ -0.47 -0.470189060762585
Escherichia coli CFT073  c0381  AAN78862.1  A0A0H2V4J1  383 aa Hypothetical protein n.s. ●○○○○ -0.47 -0.470143876295941
Serratia marcescens Strain UMH9  BVG96_15155  ASL98885.1  127 aa autonomous glycyl radical cofactor GrcA n.s. ●○○○○ -0.47 -0.470124934529319
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0034  WP_002868987.1  Q1HG73  573 aa DUF262 domain-containing protein n.s. ●○○○○ -0.47 -0.470072782879
Haemophilus influenzae Rd KW20  HI_0694  NP_438854.1  P44827  rluE  240 aa 23S rRNA pseudouridine synthase E n.s. ●○○○○ -0.47 -0.470060081421832
Mycobacterium avium subsp. paratuberculosis K10  MAP_2538  AAS04855.1  Q73WX2  283 aa hypothetical protein n.s. ●○○○○ -0.47 -0.469935353673167
Vibrio parahaemolyticus RIMD 2210633  VPA_0787  BAC62130.1  Q87I19  41 aa hypothetical protein n.s. ●○○○○ -0.47 -0.469663092408544
Mycobacterium avium subsp. paratuberculosis K10  MAP_3699c  AAS06249.1  Q73TL9  275 aa hypothetical protein n.s. ●○○○○ -0.47 -0.469449955152904
Mycobacterium avium subsp. paratuberculosis K10  MAP_0772  AAS03089.1  Q742R3  222 aa hypothetical protein n.s. ●○○○○ -0.47 -0.4694022207285
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2323  CBW18425.1  A0A0H3NDX8  hisJ  260 aa histidine-binding periplasmic protein n.s. ●○○○○ -0.47 -0.469390766137714
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4465  CBW20554.1  A0A0H3NJ76  921 aa hypothetical transcriptional regulatory protein n.s. ●○○○○ -0.47 -0.469389260724266
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3103  CBW19202.1  A0A0H3NFY0  494 aa possible aldehyde dehydrogenase n.s. ●○○○○ -0.47 -0.469377332643774
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4286  AIK82831.1  176 aa RNA pyrophosphohydrolase n.s. ●○○○○ -0.47 -0.469230690014042
Mycobacterium avium subsp. paratuberculosis K10  MAP_3353c  AAS05903.1  Q73UL3  260 aa hypothetical protein n.s. ●○○○○ -0.47 -0.469222208068691
Vibrio parahaemolyticus RIMD 2210633  VP_1145  BAC59408.1  Q87QK4  167 aa conserved hypothetical protein n.s. ●○○○○ -0.47 -0.469197808886332
Serratia marcescens Strain UMH9  BVG96_11545  ASL98218.1  884 aa ClpV1 family T6SS ATPase n.s. ●○○○○ -0.47 -0.469167139969532
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3930  CBW20021.1  A0A0H3NUK6  tatD  264 aa hypothetical deoxyribonuclease n.s. ●○○○○ -0.47 -0.468962096219272
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1246  WP_002853180.1  A0A0H3PI07  110 aa hypothetical protein n.s. ●○○○○ -0.47 -0.46869337047
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1657  WP_002868868.1  A0A0H3PIQ2  145 aa DUF411 domain-containing protein n.s. ●○○○○ -0.47 -0.468541871567
Vibrio parahaemolyticus RIMD 2210633  VPA_1237  BAC62580.1  Q87GS8  478 aa putative GntR-family regulatory protein n.s. ●○○○○ -0.47 -0.468409900946755
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2940  CBW19039.1  A0A0H3NFH1  380 aa conserved hypothetical protein n.s. ●○○○○ -0.47 -0.468350319467743
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0464  WP_002854950.1  A0A0H3PJB7  sdhB  321 aa succinate dehydrogenase/fumarate reductase iron-sulfur subunit n.s. ●○○○○ -0.47 -0.46820777479
Mycobacterium avium subsp. paratuberculosis K10  MAP_3719  AAS06269.1  Q73TJ9  207 aa hypothetical protein n.s. ●○○○○ -0.47 -0.468068321832972
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0101  CBW16204.1  A0A0H3NCN9  araD  231 aa L-ribulose-5-phosphate 4-epimerase n.s. ●○○○○ -0.47 -0.468029021119783
Serratia marcescens Strain UMH9  BVG96_13920  ASL98660.1  136 aa hypothetical protein n.s. ●○○○○ -0.47 -0.467837431575727
Serratia marcescens Strain UMH9  BVG96_09710  ASL97876.1  251 aa orotidine 5'-phosphate decarboxylase n.s. ●○○○○ -0.47 -0.467796296375817
Escherichia coli CFT073  c0414  AAN78895.1  A0A0H2V6L5  283 aa 2,5-diketo-D-gluconic acid reductase A n.s. ●○○○○ -0.47 -0.46774302168086
Mycobacterium avium subsp. paratuberculosis K10  MAP_3574  AAS06124.1  Q73TZ4  pntB  474 aa PntB n.s. ●○○○○ -0.47 -0.467697942465579
Serratia marcescens Strain UMH9  BVG96_05070  ASL97016.1  338 aa low-specificity L-threonine aldolase n.s. ●○○○○ -0.47 -0.467587480991142
Serratia marcescens Strain UMH9  BVG96_21330  ASM00002.1  238 aa flavin mononucleotide phosphatase n.s. ●○○○○ -0.47 -0.467576159548902
Escherichia coli O157:H7 str. EDL933  Z4868  AAG58603.1  524 aa periplasmic binding protein for nickel n.s. ●○○○○ -0.47 -0.467463957551766
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3625  WP_000634766.1  E8XE04  yheS  635 aa ABC transporter ATP-binding protein n.s. ●○○○○ -0.47 -0.467307969474616
Serratia marcescens Strain UMH9  BVG96_13695  ASL98617.1  252 aa phospholipid-binding lipoprotein MlaA n.s. ●○○○○ -0.47 -0.467277161864636
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3004  CBW19103.1  A0A0H3NRF6  STM3025.1N  170 aa regulatory protein n.s. ●○○○○ -0.47 -0.467273677080173
Mycobacterium avium subsp. paratuberculosis K10  MAP_0325c  AAS02642.1  Q744L6  125 aa hypothetical protein n.s. ●○○○○ -0.47 -0.467270970101371
Haemophilus influenzae Rd KW20  HI_1621  NP_439763.1  P44274  206 aa cobalt transport protein CbiM n.s. ●○○○○ -0.47 -0.467078670664253
Escherichia coli CFT073  c3341  AAN81789.1  A0A0H2VCH1  55 aa Hypothetical protein n.s. ●○○○○ -0.47 -0.467031911360678
Escherichia coli CFT073  c3340  AAN81788.1  A0A0H2VA96  384 aa Hypothetical protein n.s. ●○○○○ -0.47 -0.467031911360678
Serratia marcescens Strain UMH9  BVG96_18380  ASL99472.1  236 aa MFS transporter n.s. ●○○○○ -0.47 -0.467030969430301
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1480  WP_002804842.1  A0A0H3PAI1  ccoQ  87 aa cytochrome c oxidase, cbb3-type, CcoQ subunit n.s. ●○○○○ -0.47 -0.467008793231
Serratia marcescens Strain UMH9  BVG96_01830  ASL96422.1  104 aa BolA family transcriptional regulator n.s. ●○○○○ -0.47 -0.466959756249335
Serratia marcescens Strain UMH9  BVG96_16125  ASL99057.1  379 aa alpha-hydroxy-acid oxidizing enzyme n.s. ●○○○○ -0.47 -0.466684180507717
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1160  WP_002869018.1  A0A0H3PD15  315 aa glycosyltransferase n.s. ●○○○○ -0.47 -0.466453203185
Serratia marcescens Strain UMH9  BVG96_14105  ASL98689.1  226 aa DNA-binding response regulator n.s. ●○○○○ -0.47 -0.466430572029854
Streptococcus pyogenes M1 5448  SP5448_06705  WP_010922111.1  375 aa ABC transporter permease n.s. ●○○○○ -0.47 -0.466424759880453
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0882  WP_002869424.1  A0A0H3P9J4  620 aa aryl-sulfate sulfotransferase n.s. ●○○○○ -0.47 -0.466264752226
Escherichia coli O157:H7 str. EDL933  Z2973  AAG56905.1  80 aa unknown protein encoded by prophage CP-933T n.s. ●○○○○ -0.47 -0.466261857222987
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4514  AIK83052.1  143 aa hypothetical protein n.s. ●○○○○ -0.47 -0.466082503740397
Mycobacterium avium subsp. paratuberculosis K10  MAP_3013c  AAS05561.1  Q73VK0  296 aa hypothetical protein n.s. ●○○○○ -0.47 -0.465821820998258
Serratia marcescens Strain UMH9  BVG96_15395  ASL98932.1  368 aa proline/betaine ABC transporter permease ProW n.s. ●○○○○ -0.47 -0.465798515122546
Vibrio parahaemolyticus RIMD 2210633  VPA_0033  BAC61376.1  Q87K65  285 aa putative ABC transporter ATP-binding protein n.s. ●○○○○ -0.47 -0.465639915008753
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0537  WP_009882250.1  A0A0H3PBW9  clpB  857 aa AAA family ATPase n.s. ●○○○○ -0.47 -0.465545600705
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0676  WP_001669181.1  E8XA14  ybeR  235 aa DUF1266 domain-containing protein n.s. ●○○○○ -0.47 -0.465431686940481
Vibrio parahaemolyticus RIMD 2210633  VP_0461  BAC58724.1  Q87SG3  murC  490 aa UDP-N-acetylmuramate-alanine ligase n.s. ●○○○○ -0.47 -0.465312946320017
Serratia marcescens Strain UMH9  BVG96_04465  ASL96900.1  209 aa hypothetical protein n.s. ●○○○○ -0.47 -0.465307996400519
Escherichia coli M12  CO715_06355  ATI05373.1  98 aa hypothetical protein n.s. ●○○○○ -0.47 -0.465190100546244
Streptococcus pyogenes M1 5448  SP5448_04510  WP_011285570.1  441 aa phage portal protein n.s. ●○○○○ -0.47 -0.465175022432969
Serratia marcescens Strain UMH9  BVG96_18910  ASL99565.1  849 aa nitrite reductase large subunit n.s. ●○○○○ -0.46 -0.464989509053465
Haemophilus influenzae Rd KW20  HI_1102  NP_439259.1  P45039  cysZ  272 aa sulfate transport protein CysZ n.s. ●○○○○ -0.46 -0.464877138974837
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0449  CBW16550.1  A0A0H3NIF4  ybaX  231 aa conserved hypothetical protein n.s. ●○○○○ -0.46 -0.464855983549069
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1072  CBW17168.1  A0A0H3NAH4  ycdW  312 aa hypothetical 2-hydroxyacid dehydrogenase in phoh-csgg intergenic region n.s. ●○○○○ -0.46 -0.464835115730053
Serratia marcescens Strain UMH9  BVG96_22265  ASM00167.1  542 aa isovaleryl-CoA dehydrogenase n.s. ●○○○○ -0.46 -0.464797059166239
Serratia marcescens Strain UMH9  BVG96_01020  ASM00444.1  414 aa aminotransferase V n.s. ●○○○○ -0.46 -0.464768519166103
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1653  CBW17748.1  A0A0H3NH95  trpH  293 aa conserved hypothetical protein n.s. ●○○○○ -0.46 -0.464768141753682
Vibrio parahaemolyticus RIMD 2210633  VP_1183  BAC59446.1  Q87QG6  clsA  484 aa cardiolipin synthase n.s. ●○○○○ -0.46 -0.464616796304714
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