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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0107  WP_000852387.1  E8XH12  araC  281 aa arabinose operon transcriptional regulator AraC n.s. ●○○○○ -0.19 -0.194917121369095
Acinetobacter baumannii ATCC 17978  A1S_1875  ABO12302.2  270 aa pca operon regulatory protein n.s. ●○○○○ -0.19 -0.194868065964509
Mycobacterium avium subsp. paratuberculosis K10  MAP_0920c  AAS03237.1  Q742B7  mscL  151 aa MscL n.s. ●○○○○ -0.19 -0.194813302290842
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0177  WP_000946047.1  E8XHW6  cueO  536 aa multicopper oxidase CueO n.s. ●○○○○ -0.19 -0.194726941566656
Escherichia coli CFT073  c3204  AAN81656.1  A0A0H2VA04  390 aa Hypothetical protein n.s. ●○○○○ -0.19 -0.194712253408997
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0628  NP_230277.1  Q9KU95  366 aa hypothetical protein n.s. ●○○○○ -0.19 -0.194576065374837
Haemophilus influenzae Rd KW20  HI_1398  NP_439551.1  P71384  fumC  464 aa fumarate hydratase n.s. ●○○○○ -0.19 -0.194439904811695
Streptococcus pyogenes M1 5448  SP5448_05005  WP_010922338.1  521 aa ABC-F family ATP-binding cassette domain-containing protein n.s. ●○○○○ -0.19 -0.194366530928114
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2277  CBW18379.1  A0A0H3NJM0  yfbB  252 aa conserved hypothetical protein n.s. ●○○○○ -0.19 -0.194124696767595
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0455  CBW16556.1  A0A0H3NA27  mdlB  593 aa hypothetical ABC transporter ATP-binding membrane protein n.s. ●○○○○ -0.19 -0.194037506146902
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2279  CBW18381.1  A0A0H3NNW7  menF  431 aa isochorismate synthase n.s. ●○○○○ -0.19 -0.194020625562921
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4360  WP_000617942.1  E8XLC0  zraR  441 aa sigma-54-dependent response regulator transcription factor ZraR n.s. ●○○○○ -0.19 -0.19398470372924
Serratia marcescens Strain UMH9  BVG96_06505  ASL97286.1  844 aa fimbrial protein n.s. ●○○○○ -0.19 -0.193947258015055
Escherichia coli CFT073  c3429  AAN81874.1  A0A0H2VAF4  346 aa Tas protein n.s. ●○○○○ -0.19 -0.193728376257607
Mycobacterium avium subsp. paratuberculosis K10  MAP_1320c  AAS03637.1  Q740N0  404 aa hypothetical protein n.s. ●○○○○ -0.19 -0.193626582782566
Serratia marcescens Strain UMH9  BVG96_05065  ASL97015.1  231 aa N-acetylmannosamine-6-phosphate 2-epimerase n.s. ●○○○○ -0.19 -0.193453081255927
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1503  WP_079254195.1  A0A0H3PIR1  fdhA  934 aa formate dehydrogenase n.s. ●○○○○ -0.19 -0.193440509056
Haemophilus influenzae Rd KW20  HI_0952  NP_439113.2  P44952  221 aa DNA repair protein RadC n.s. ●○○○○ -0.19 -0.193394675888124
Serratia marcescens Strain UMH9  BVG96_13385  ASL98557.1  317 aa transketolase n.s. ●○○○○ -0.19 -0.193102877793741
Streptococcus pyogenes M1 5448  SP5448_03730  WP_002987582.1  91 aa hypothetical protein n.s. ●○○○○ -0.19 -0.193020659830824
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1891  CBW17986.1  A0A0H3NI05  fliT  122 aa flagellar protein FliT n.s. ●○○○○ -0.19 -0.192953642618849
Mycobacterium avium subsp. paratuberculosis K10  MAP_3031  AAS05579.1  Q73VI2  434 aa hypothetical protein n.s. ●○○○○ -0.19 -0.192938861319942
Escherichia coli CFT073  c1145  AAN79613.1  Q8FJ44  rutE  196 aa Putative NADH dehydrogenase/NAD(P)H nitroreductase ycdI n.s. ●○○○○ -0.19 -0.192825448804481
Acinetobacter baumannii ATCC 17978  A1S_1600  ABO12027.2  182 aa lysozyme n.s. ●○○○○ -0.19 -0.192767358138796
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1426  AIK80047.1  214 aa DSBA-like thioredoxin domain protein n.s. ●○○○○ -0.19 -0.192662354880551
Vibrio parahaemolyticus RIMD 2210633  VPA_1668  BAC63011.1  Q87FL1  32 aa hypothetical protein n.s. ●○○○○ -0.19 -0.192367525222996
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1004  WP_002869228.1  A0A0H3P9U4  hipO  383 aa amidohydrolase n.s. ●○○○○ -0.19 -0.192242189662
Vibrio parahaemolyticus RIMD 2210633  VP_2065  BAC60328.1  Q87N11  201 aa cob(I)alamin adenosyltransferase n.s. ●○○○○ -0.19 -0.192206086770076
Mycobacterium avium subsp. paratuberculosis K10  MAP_1676  AAS03993.1  Q73ZC7  357 aa hypothetical protein n.s. ●○○○○ -0.19 -0.192155923545942
Escherichia coli CFT073  c0901  AAN79374.1  A0A0H2V5H9  ybiP  527 aa Hypothetical protein ybiP n.s. ●○○○○ -0.19 -0.192076948812916
Acinetobacter baumannii ATCC 17978  A1S_0363  ABO10823.2  109 aa hypothetical protein n.s. ●○○○○ -0.19 -0.19202961385457
Serratia marcescens Strain UMH9  BVG96_04865  ASL96976.1  244 aa phosphoesterase n.s. ●○○○○ -0.19 -0.192015791544761
Serratia marcescens Strain UMH9  BVG96_16985  ASL99213.1  184 aa hypothetical protein n.s. ●○○○○ -0.19 -0.191840294246008
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2825  CBW18923.1  A0A0H3NL36  hycI  156 aa hydrogenase 3 maturation protease n.s. ●○○○○ -0.19 -0.191755443412884
Escherichia coli CFT073  c1273  AAN79747.1  A0A0H2V731  1091 aa Antigen 43 precursor n.s. ●○○○○ -0.19 -0.191738360366871
Streptococcus pyogenes M1 5448  SP5448_06735  WP_010922108.1  316 aa streptolysin S biosynthesis dehydrogenase SagB n.s. ●○○○○ -0.19 -0.19148252143392
Mycobacterium avium subsp. paratuberculosis K10  MAP_0577  AAS02894.1  Q743K8  281 aa hypothetical protein n.s. ●○○○○ -0.19 -0.191455794298316
Serratia marcescens Strain UMH9  BVG96_11855  ASL98277.1  252 aa phenylacetate-CoA oxygenase subunit PaaI n.s. ●○○○○ -0.19 -0.191430381340053
Haemophilus influenzae Rd KW20  HI_0374  NP_438535.1  P44670  228 aa hypothetical protein n.s. ●○○○○ -0.19 -0.19140625401179
Haemophilus influenzae Rd KW20  HI_0420  NP_438582.1  P43995  99 aa hypothetical protein n.s. ●○○○○ -0.19 -0.19140625401179
Haemophilus influenzae Rd KW20  HI_1222  NP_439378.1  P44129  lapA  97 aa hypothetical protein n.s. ●○○○○ -0.19 -0.19140625401179
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1360  WP_010891930.1  A0A0H3PI21  nrfH  171 aa cytochrome c nitrite reductase small subunit n.s. ●○○○○ -0.19 -0.191390113569
Streptococcus pyogenes M1 5448  SP5448_05035  WP_011285545.1  520 aa signal recognition particle protein n.s. ●○○○○ -0.19 -0.191386387784114
Streptococcus pyogenes M1 5448  SP5448_06950  WP_010922039.1  162 aa PTS system mannose/fructose/N-acetylgalactosamine-transporter subunit IIB n.s. ●○○○○ -0.19 -0.191386387784114
Vibrio parahaemolyticus RIMD 2210633  VPA_0727  BAC62070.1  Q87I79  362 aa putative nonspecific tight adherence protein TadD n.s. ●○○○○ -0.19 -0.191346023272934
Vibrio parahaemolyticus RIMD 2210633  VP_1721  BAC59984.1  Q87NZ7  ectB  421 aa diaminobutyrate-pyruvate aminotransferase n.s. ●○○○○ -0.19 -0.191202571032672
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4136  CBW20224.1  A0A0H3NVA4  210 aa hypothetical bacteriophage protein n.s. ●○○○○ -0.19 -0.191167788171754
Escherichia coli CFT073  c0488  AAN78966.1  A0A0H2V4T1  40 aa Hypothetical protein n.s. ●○○○○ -0.19 -0.191116728868985
Vibrio parahaemolyticus RIMD 2210633  VPA_1446  BAC62789.1  Q87G71  218 aa putative transcriptional regulator, LuxR family n.s. ●○○○○ -0.19 -0.190957267739839
Serratia marcescens Strain UMH9  BVG96_04805  ASL96964.1  254 aa molecular chaperone n.s. ●○○○○ -0.19 -0.190894884255554
Acinetobacter baumannii ATCC 17978  A1S_0245  ABO10720.2  A3M1C6  murD  448 aa UDP-N-acetylmuramoylalanine-D-glutamate ligase n.s. ●○○○○ -0.19 -0.190702315853088
Acinetobacter baumannii ATCC 17978  A1S_1802  ABO12229.2  152 aa hypothetical protein n.s. ●○○○○ -0.19 -0.190563246111836
Escherichia coli CFT073  c4127  AAN82565.1  A0A0H2VBH0  yheS  637 aa Hypothetical ABC transporter ATP-binding protein yheS n.s. ●○○○○ -0.19 -0.190476247334867
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2921  AIK81507.1  191 aa transcriptional regulatory, C terminal family protein n.s. ●○○○○ -0.19 -0.190464937979509
Vibrio parahaemolyticus RIMD 2210633  VPA_1045  BAC62388.1  Q87HC0  511 aa hypothetical protein n.s. ●○○○○ -0.19 -0.190403734387764
Escherichia coli M12  CO715_07070  ATI05497.1  130 aa regulator n.s. ●○○○○ -0.19 -0.190403299780494
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0929  WP_002865902.1  A1VZQ5  peb1C  242 aa amino acid ABC transporter ATP-binding protein n.s. ●○○○○ -0.19 -0.190283698164
Mycobacterium avium subsp. paratuberculosis K10  MAP_3871  AAS06421.1  Q73T48  purT  420 aa PurT n.s. ●○○○○ -0.19 -0.190254797407955
Escherichia coli O157:H7 str. EDL933  Z6021  AAK16937.1  303 aa orf, hypothetical protein n.s. ●○○○○ -0.19 -0.190224126370155
Serratia marcescens Strain UMH9  BVG96_04400  ASL96887.1  345 aa DNA-binding transcriptional regulator GalS n.s. ●○○○○ -0.19 -0.18986255902463
Vibrio parahaemolyticus RIMD 2210633  VPA_0420  BAC61763.1  Q87J33  153 aa LuxT n.s. ●○○○○ -0.19 -0.189773620683535
Streptococcus pyogenes M1 5448  SP5448_01330  WP_002986037.1  246 aa amino acid ABC transporter ATP-binding protein n.s. ●○○○○ -0.19 -0.189655982087597
Serratia marcescens Strain UMH9  BVG96_19605  ASL99695.1  162 aa ATP-independent periplasmic protein-refolding chaperone n.s. ●○○○○ -0.19 -0.18947961971312
Mycobacterium avium subsp. paratuberculosis K10  MAP_2548c  AAS04865.1  Q73WW2  lpqY  470 aa LpqY n.s. ●○○○○ -0.19 -0.189186305069711
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1489  CBW17584.1  A0A0H3ND48  842 aa hypothetical hydrolase n.s. ●○○○○ -0.19 -0.189165992812462
Serratia marcescens Strain UMH9  BVG96_18520  ASL99492.1  68 aa alternative ribosome-rescue factor A n.s. ●○○○○ -0.19 -0.189164695489038
Serratia marcescens Strain UMH9  BVG96_11345  ASL98181.1  356 aa flagellar motor protein MotB n.s. ●○○○○ -0.19 -0.1889224986034
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0249  WP_000560527.1  E8XIR0  yaej  140 aa aminoacyl-tRNA hydrolase n.s. ●○○○○ -0.19 -0.188885987136287
Escherichia coli CFT073  c5385  AAN83807.1  A0A0H2VGG6  109 aa Hypothetical protein n.s. ●○○○○ -0.19 -0.188867898039829
Escherichia coli CFT073  c0165  AAN78659.1  Q8FL30  panB  264 aa 3-methyl-2-oxobutanoate hydroxymethyltransferase n.s. ●○○○○ -0.19 -0.188680834404792
Serratia marcescens Strain UMH9  BVG96_18325  ASL99461.1  602 aa sodium:proton exchanger n.s. ●○○○○ -0.19 -0.188492822984227
Acinetobacter baumannii ATCC 17978  A1S_1969  ABO12396.2  855 aa putative outer membrane protein n.s. ●○○○○ -0.19 -0.188273553980207
Mycobacterium avium subsp. paratuberculosis K10  MAP_1783  AAS04100.1  Q73Z20  209 aa hypothetical protein n.s. ●○○○○ -0.19 -0.18819327391822
Mycobacterium avium subsp. paratuberculosis K10  MAP_3009c  AAS05557.1  Q73VK4  recG  738 aa RecG n.s. ●○○○○ -0.19 -0.188117142602056
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0390  WP_000830784.1  E8XJS4  ampH  385 aa D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH n.s. ●○○○○ -0.19 -0.188082961952669
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1539  CBW17634.1  A0A0H3ND77  tehA  337 aa tellurite resistance protein TehA n.s. ●○○○○ -0.19 -0.188066486778624
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0095  CBW16197.1  A0A0H3N7H5  djlA  270 aa DnaJ-like protein n.s. ●○○○○ -0.19 -0.187989077044765
Mycobacterium avium subsp. paratuberculosis K10  MAP_2282c  AAS04599.1  Q73XM7  tig  464 aa Tig n.s. ●○○○○ -0.19 -0.187879572276763
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4162  CBW20250.1  A0A0H3NKD6  yjbA  136 aa hypothetical membrane protein n.s. ●○○○○ -0.19 -0.187777546730142
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0317  CBW16418.1  A0A0H3N9L9  proB  367 aa glutamate 5-kinase n.s. ●○○○○ -0.19 -0.187457278963651
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0048  CBW16149.1  A0A0H3N7M5  lspA  166 aa lipoprotein signal peptidase n.s. ●○○○○ -0.19 -0.187417212279852
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4294  WP_000424866.1  E8XL66  talC  220 aa fructose-6-phosphate aldolase n.s. ●○○○○ -0.19 -0.187395111426817
Escherichia coli CFT073  c0005  AAN78505.1  A0A0H2V5R3  thrC  428 aa Threonine synthase n.s. ●○○○○ -0.19 -0.187359422786772
Vibrio parahaemolyticus RIMD 2210633  VP_1751  BAC60014.1  Q87NW7  metAS  313 aa homoserine O-succinyltransferase n.s. ●○○○○ -0.19 -0.187283490385724
Acinetobacter baumannii ATCC 17978  A1S_2931  ABO13336.2  120 aa hypothetical protein n.s. ●○○○○ -0.19 -0.187252819189685
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4227  WP_000143970.1  E8XKB2  rhaB  489 aa rhamnulokinase n.s. ●○○○○ -0.19 -0.187140923488267
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0921  WP_002856266.1  A0A0H3P9J5  ciaB  610 aa invasion protein CiaB n.s. ●○○○○ -0.19 -0.187112094219
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0451  NP_232844.1  H9L4S7  166 aa hypothetical protein n.s. ●○○○○ -0.19 -0.18705011715564
Mycobacterium avium subsp. paratuberculosis K10  MAP_0267c  AAS02584.1  Q745S1  352 aa hypothetical protein n.s. ●○○○○ -0.19 -0.18688163820382
Acinetobacter baumannii ATCC 17978  A1S_2623  ABO13040.2  264 aa hypothetical protein n.s. ●○○○○ -0.19 -0.186853711744231
Vibrio parahaemolyticus RIMD 2210633  VP_1597  BAC59860.1  Q87PC0  rlmL  707 aa putative N6-adenine-specific DNA methylase n.s. ●○○○○ -0.19 -0.186508136308296
Escherichia coli M12  CO715_04880  ATI05125.1  367 aa phosphoporin PhoE n.s. ●○○○○ -0.19 -0.186439025509766
Acinetobacter baumannii ATCC 17978  A1S_3411  ABO13800.2  421 aa Putative GTPases (G3E family) n.s. ●○○○○ -0.19 -0.18639444599708
Vibrio parahaemolyticus RIMD 2210633  VPA_1746  BAC63089.1  Q87FD3  221 aa hypothetical protein n.s. ●○○○○ -0.19 -0.186353744333343
Mycobacterium avium subsp. paratuberculosis K10  MAP_1709c  AAS04026.1  Q73Z94  fadD11  606 aa FadD11_2 n.s. ●○○○○ -0.19 -0.186218348870288
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1542  WP_002851392.1  A0A0H3PE61  110 aa transcriptional regulator n.s. ●○○○○ -0.19 -0.186217492465
Serratia marcescens Strain UMH9  BVG96_03545  ASL96727.1  118 aa DUF4810 domain-containing protein n.s. ●○○○○ -0.19 -0.186079306112577
Porphyromonas gingivalis ATCC 33277  PGN_1262  WP_012458150.1  B2RK86  cbiA  439 aa cobyrinate a,c-diamide synthase n.s. ●○○○○ -0.19 -0.186057010090907
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0642  WP_002868908.1  A0A0H3PEG8  331 aa phosphate ABC transporter substrate-binding protein n.s. ●○○○○ -0.19 -0.186000860942
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2181  CBW18277.1  A0A0H3NNK8  fruA  562 aa PTS system, fructose-specific IIBC component n.s. ●○○○○ -0.19 -0.185980802530306
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