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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli CFT073  c0814  AAN79287.1  P0AAV1  ybgE  97 aa Protein ybgE n.s. ●●○○○ -1.07 -1.07368925180152
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3170  AIK81742.1  850 aa adenylate cyclase, class-I family protein n.s. ●●○○○ -1.07 -1.07359756042407
Vibrio parahaemolyticus RIMD 2210633  VPA_1166  BAC62509.1  Q87GZ9  clcA  467 aa conserved hypothetical protein n.s. ●●○○○ -1.07 -1.07355812767358
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0560  CBW16660.1  A0A0H3N8Q4  328 aa similar to a hypothetical phospohtase isomerase n.s. ●●○○○ -1.07 -1.07345942161377
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3409  CBW19504.1  A0A0H3NSU6  hopD  155 aa Type III leader peptidase n.s. ●●○○○ -1.07 -1.07334061406609
Streptococcus pyogenes M1 5448  SP5448_01560  WP_002982888.1  398 aa phosphoglycerate kinase n.s. ●●○○○ -1.07 -1.07302809015934
Mycobacterium avium subsp. paratuberculosis K10  MAP_0171c  AAS02488.1  Q745H1  384 aa hypothetical protein n.s. ●●○○○ -1.07 -1.07299443743521
Vibrio parahaemolyticus RIMD 2210633  VP_0737  BAC59000.1  Q87RP0  ychF  383 aa GTP-binding protein n.s. ●●○○○ -1.07 -1.07282342190178
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2977  CBW19076.1  A0A0H3NFN4  comO  187 aa competence gene n.s. ●●○○○ -1.07 -1.07266898405419
Escherichia coli O157:H7 str. EDL933  Z1454  AAG55581.1  175 aa putative DNA N-6-adenine-methyltransferase of bacteriophage BP-933W n.s. ●●○○○ -1.07 -1.07239944726297
Escherichia coli CFT073  c1822  AAN80286.1  A0A0H2V9G6  ompN  377 aa Outer membrane protein N precursor n.s. ●●○○○ -1.07 -1.07239676759192
Serratia marcescens Strain UMH9  BVG96_03060  ASL96635.1  331 aa 6-phosphogluconolactonase n.s. ●●○○○ -1.07 -1.07184873271056
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3705  CBW19799.1  A0A0H3NN00  ligB  561 aa hypothetical DNA ligase n.s. ●●○○○ -1.07 -1.07163656880437
Mycobacterium avium subsp. paratuberculosis K10  MAP_0653  AAS02970.1  Q743D2  pstA1  304 aa PstA1_1 n.s. ●●○○○ -1.07 -1.07153560858124
Escherichia coli CFT073  c2619  AAN81075.1  P69813  gatA  150 aa PTS system, galactitol-specific IIA component n.s. ●●○○○ -1.07 -1.07132656619282
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3747  CBW19838.1  A0A0H3NTX2  494 aa hypothetical sugar (pentulose and hexulose) kinase n.s. ●●○○○ -1.07 -1.07088576578629
Escherichia coli CFT073  c2533  AAN80987.1  A0A0H2VAX6  yeeW  64 aa Hypothetical protein yeeW n.s. ●●○○○ -1.07 -1.07076077066233
Mycobacterium avium subsp. paratuberculosis K10  MAP_0180  AAS02497.1  Q745I3  489 aa hypothetical protein n.s. ●●○○○ -1.07 -1.0707416058555
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1451  WP_002869189.1  A0A0H3PE35  thiL  273 aa thiamine-phosphate kinase n.s. ●●○○○ -1.07 -1.07073080422
Vibrio parahaemolyticus RIMD 2210633  VP_0663  BAC58926.1  Q87RW3  tadA  161 aa YfhC protein n.s. ●●○○○ -1.07 -1.07059710750291
Escherichia coli CFT073  c2913  AAN81363.1  A0A0H2V9A3  45 aa Hypothetical protein n.s. ●●○○○ -1.07 -1.07029650446128
Streptococcus pyogenes M1 5448  SP5448_03620  WP_002994106.1  118 aa hypothetical protein n.s. ●●○○○ -1.07 -1.07014408066515
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2886  CBW18985.1  A0A0H3NL92  pphB  218 aa possible serine/threonine protein phosphatase n.s. ●●○○○ -1.07 -1.06948049467803
Haemophilus influenzae Rd KW20  HI_0176  NP_438344.1  P44445  rluD  324 aa 23S rRNA pseudouridine synthase D n.s. ●●○○○ -1.07 -1.06933732865249
Haemophilus influenzae Rd KW20  HI_0282  NP_438450.1  P44611  menH  247 aa acyl-CoA thioester hydrolase YfbB n.s. ●●○○○ -1.07 -1.06933732865249
Haemophilus influenzae Rd KW20  HI_1741  NP_439885.2  P43811  spoT  704 aa guanosine-3'5'-bis(diphosphate) 3'- pyrophosphohydrolase n.s. ●●○○○ -1.07 -1.06933732865249
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3491  CBW19585.1  A0A0H3NH07  glpG  276 aa hypothetical membrane protein n.s. ●●○○○ -1.07 -1.06905964999129
Escherichia coli CFT073  c2303  AAN80762.1  A0A0H2V832  cheA  672 aa Chemotaxis protein cheA n.s. ●●○○○ -1.07 -1.06863756199174
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0339  CBW16439.1  A0A0H3N9P5  247 aa possible transmembrane regulator n.s. ●●○○○ -1.07 -1.06860745441846
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1213  WP_002868865.1  Q3I354  luxS  164 aa S-ribosylhomocysteine lyase n.s. ●●○○○ -1.07 -1.06852613742
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4128  CBW20216.1  A0A0H3NID0  yjbC  289 aa hypothetical pseudouridine synthase n.s. ●●○○○ -1.07 -1.06834587165887
Streptococcus pyogenes M1 5448  SP5448_00715  WP_076640009.1  146 aa signal peptidase I n.s. ●●○○○ -1.07 -1.06726007117095
Escherichia coli O157:H7 str. EDL933  Z0597  AAG54827.1  558 aa putative transport protein n.s. ●●○○○ -1.07 -1.06714765285419
Escherichia coli O157:H7 str. EDL933  Z2386  AAG56428.1  463 aa unknown protein encoded within prophage CP-933R n.s. ●●○○○ -1.07 -1.06714765285419
Escherichia coli O157:H7 str. EDL933  Z0474  AAG54724.1  364 aa orf, hypothetical protein n.s. ●●○○○ -1.07 -1.06714765285419
Streptococcus pyogenes M1 5448  SP5448_02230  WP_002988681.1  137 aa hypothetical protein n.s. ●●○○○ -1.07 -1.06629873467289
Mycobacterium avium subsp. paratuberculosis K10  MAP_3444  AAS05994.1  Q73UC4  sdhB  267 aa SdhB n.s. ●●○○○ -1.07 -1.06609667633297
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4390  CBW20478.1  A0A0H3NJ94  pyrI  153 aa aspartate carbamoyltransferase regulatory subunit n.s. ●●○○○ -1.07 -1.06563060597531
Vibrio parahaemolyticus RIMD 2210633  VPA_0248  BAC61591.1  Q87JK1  325 aa putative outer membrane protein OmpA n.s. ●●○○○ -1.07 -1.06553318772299
Mycobacterium avium subsp. paratuberculosis K10  MAP_3947  AAS06497.1  Q73SX6  mmpL4  976 aa MmpL4_7 n.s. ●●○○○ -1.06 -1.06469866573219
Streptococcus pyogenes M1 5448  SP5448_06325  WP_002993627.1  228 aa ABC transporter ATP-binding protein n.s. ●●○○○ -1.06 -1.06437606167676
Serratia marcescens Strain UMH9  BVG96_10155  ASL97959.1  618 aa signal peptide peptidase A n.s. ●●○○○ -1.06 -1.06425384073409
Vibrio parahaemolyticus RIMD 2210633  VPA_1108  BAC62451.1  Q87H57  244 aa putative NAD(P)H-flavin reductase n.s. ●●○○○ -1.06 -1.0641074566977
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0327  WP_002854367.1  A0A0H3PC30  203 aa DUF452 family protein n.s. ●●○○○ -1.06 -1.06375666764
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4057  CBW20146.1  A0A0H3NIJ7  yijF  207 aa conserved hypothetical protein n.s. ●●○○○ -1.06 -1.06340402501667
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1710  CBW17805.1  A0A0H3NLZ6  ychH  92 aa hypothetical exported protein n.s. ●●○○○ -1.06 -1.06283951821673
Mycobacterium avium subsp. paratuberculosis K10  MAP_0280  AAS02597.1  Q745S4  celA  329 aa CelA n.s. ●●○○○ -1.06 -1.0626220993649
Escherichia coli O157:H7 str. EDL933  Z0052  AAG54349.1  176 aa putative NAD(P)H oxidoreductase n.s. ●●○○○ -1.06 -1.06258238568917
Escherichia coli CFT073  c1888  AAN80348.1  A0A0H2V9J9  801 aa Conserved hypothetical protein n.s. ●●○○○ -1.06 -1.06257438899683
Mycobacterium avium subsp. paratuberculosis K10  MAP_3908  AAS06458.1  Q73T12  lpqM  481 aa LpqM n.s. ●●○○○ -1.06 -1.06249055451393
Streptococcus pyogenes M1 5448  SP5448_00220  WP_010921773.1  484 aa amidophosphoribosyltransferase n.s. ●●○○○ -1.06 -1.06245338868063
Streptococcus pyogenes M1 5448  SP5448_00870  WP_015055903.1  451 aa nicotine adenine dinucleotide glycohydrolase n.s. ●●○○○ -1.06 -1.06245338868063
Porphyromonas gingivalis ATCC 33277  PGN_1173  WP_005873659.1  B2RJZ7  261 aa electron transfer flavoprotein subunit beta/FixA family protein n.s. ●●○○○ -1.06 -1.06236137143782
Escherichia coli CFT073  c1466  AAN79935.1  A0A0H2V6G6  1230 aa Putative tail component of prophage n.s. ●●○○○ -1.06 -1.06165525442572
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0858  WP_002859520.1  A0A0H3PHM5  mobB  161 aa lipoprotein n.s. ●●○○○ -1.06 -1.06141746363
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0858  WP_002856787.1  A0A0H3PHM5  mobB  163 aa molybdopterin-guanine dinucleotide biosynthesis protein B n.s. ●●○○○ -1.06 -1.06141746363
Serratia marcescens Strain UMH9  BVG96_07525  ASL97471.1  341 aa transcriptional repressor PurR n.s. ●●○○○ -1.06 -1.06072631522996
Vibrio parahaemolyticus RIMD 2210633  VP_1416  BAC59679.1  Q87PT5  197 aa hypothetical protein n.s. ●●○○○ -1.06 -1.06057258348053
Escherichia coli CFT073  c2147  AAN80606.1  Q8FH00  astA  315 aa Arginine N-succinyltransferase n.s. ●●○○○ -1.06 -1.0605704012884
Streptococcus pyogenes M1 5448  SP5448_03995  WP_002989242.1  72 aa redoxin NrdH n.s. ●●○○○ -1.06 -1.0605307156845
Serratia marcescens Strain UMH9  BVG96_00290  ASL96141.1  200 aa 3-isopropylmalate dehydratase small subunit n.s. ●●○○○ -1.06 -1.05938322059608
Escherichia coli CFT073  c0992  AAN79465.1  Q8FJE7  rlmC  375 aa Hypothetical RNA methyltransferase ybjF n.s. ●●○○○ -1.06 -1.0591158617756
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0214  WP_002854239.1  A0A0H3PJE1  452 aa HlyC/CorC family transporter n.s. ●●○○○ -1.06 -1.05897096425
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1880  CBW17975.1  A0A0H3NHZ5  yecC  250 aa hypothetical ABC-transport ATP-binding protein n.s. ●●○○○ -1.06 -1.05876513587009
Mycobacterium avium subsp. paratuberculosis K10  MAP_1785  AAS04102.1  Q744S1  406 aa hypothetical protein n.s. ●●○○○ -1.06 -1.05869901428392
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1113  WP_002856545.1  A0A0H3PCY2  cutE  441 aa apolipoprotein N-acyltransferase n.s. ●●○○○ -1.06 -1.0581544417
Mycobacterium avium subsp. paratuberculosis K10  MAP_2176c  AAS04493.1  Q73XY2  254 aa hypothetical protein n.s. ●●○○○ -1.06 -1.05813171771777
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1184  WP_002822505.1  A0A0H3P9S8  75 aa hypothetical protein n.s. ●●○○○ -1.06 -1.05812653284
Vibrio parahaemolyticus RIMD 2210633  VPA_0625  BAC61968.1  Q87II1  300 aa putative 3-hydroxyisobutyrate dehydrogenase n.s. ●●○○○ -1.06 -1.05765957407035
Mycobacterium avium subsp. paratuberculosis K10  MAP_1467c  AAS03784.1  Q73ZY4  389 aa hypothetical protein n.s. ●●○○○ -1.06 -1.05698615687605
Streptococcus pyogenes M1 5448  SP5448_02805  WP_010922549.1  384 aa class I SAM-dependent RNA methyltransferase n.s. ●●○○○ -1.06 -1.05572403319418
Streptococcus pyogenes M1 5448  SP5448_04250  WP_002984216.1  79 aa D-alanine--poly(phosphoribitol) ligase subunit DltC n.s. ●●○○○ -1.06 -1.05572403319418
Mycobacterium avium subsp. paratuberculosis K10  MAP_0129  AAS02446.1  Q745C6  351 aa hypothetical protein n.s. ●●○○○ -1.06 -1.0556072547152
Mycobacterium avium subsp. paratuberculosis K10  MAP_1274  AAS03591.1  Q740R8  bioA  438 aa BioA n.s. ●●○○○ -1.06 -1.05550956783455
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2044  CBW18140.1  A0A0H3ND89  sbcB  476 aa exodeoxyribonuclease I n.s. ●●○○○ -1.06 -1.05539204857488
Escherichia coli CFT073  c3441  AAN81886.1  A0A0H2VA72  yqeF  394 aa Probable acetyl-CoA acetyltransferase n.s. ●●○○○ -1.06 -1.05531804384804
Mycobacterium avium subsp. paratuberculosis K10  MAP_1671  AAS03988.1  Q73ZD2  264 aa hypothetical protein n.s. ●●○○○ -1.06 -1.0550980214102
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0639  WP_002868906.1  A0A0H3PJC1  336 aa DUF459 domain-containing protein n.s. ●●○○○ -1.05 -1.05470278281
Escherichia coli CFT073  c2264  AAN80721.1  A0A0H2VAA0  edd  625 aa Phosphogluconate dehydratase n.s. ●●○○○ -1.05 -1.0544822366815
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3575  CBW19669.1  A0A0H3NIV6  yhjG  686 aa hypothetical membrane protein n.s. ●●○○○ -1.05 -1.05441947666523
Escherichia coli O157:H7 str. EDL933  Z5567  AAG59189.1  245 aa thiamin biosynthesis, thiazole moiety n.s. ●●○○○ -1.05 -1.05363257827186
Escherichia coli CFT073  c2214  AAN80673.1  A0A0H2VA71  yoaC  119 aa Hypothetical protein yoaC n.s. ●●○○○ -1.05 -1.05345716878431
Mycobacterium avium subsp. paratuberculosis K10  MAP_2220  AAS04537.1  Q73XT9  rnz  280 aa hypothetical protein n.s. ●●○○○ -1.05 -1.05318078042301
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0844  WP_011812739.1  A1VZH1  truA  241 aa tRNA pseudouridine(38-40) synthase TruA n.s. ●●○○○ -1.05 -1.05289343957
Streptococcus pyogenes M1 5448  SP5448_03420  WP_003056941.1  290 aa polyprenyl synthetase family protein n.s. ●●○○○ -1.05 -1.05284002369998
Mycobacterium avium subsp. paratuberculosis K10  MAP_2559  AAS04876.1  Q73WV1  267 aa hypothetical protein n.s. ●●○○○ -1.05 -1.05282290237628
Escherichia coli O157:H7 str. EDL933  Z2309  AAG56362.1  125 aa hypothetical protein n.s. ●●○○○ -1.05 -1.05178948752398
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2992  CBW19091.1  A0A0H3NLT2  lysR  311 aa transcriptional activator protein LysR n.s. ●●○○○ -1.05 -1.05137921785724
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4003  CBW20092.1  A0A0H3NK10  327 aa trap dicarboxylate transporter, dctp subunit n.s. ●●○○○ -1.05 -1.05132911751572
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3598  CBW19692.1  A0A0H3NMT6  374 aa conserved hypothetical protein n.s. ●●○○○ -1.05 -1.05107969298505
Escherichia coli CFT073  c2477  AAN80936.1  Q8FGA5  cobT  359 aa Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase n.s. ●●○○○ -1.05 -1.05074582043402
Vibrio parahaemolyticus RIMD 2210633  VPA_0928  BAC62271.1  Q87HN5  145 aa hypothetical protein n.s. ●●○○○ -1.05 -1.0497461814814
Haemophilus influenzae Rd KW20  HI_0038  NP_438211.1  P44475  mreC  351 aa rod shape-determining protein MreC n.s. ●●○○○ -1.05 -1.04955006687806
Escherichia coli O157:H7 str. EDL933  Z5471  AAG59119.1  509 aa glycerol kinase n.s. ●●○○○ -1.05 -1.0490011420303
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4456  CBW20545.1  A0A0H3NQ01  hsdM  529 aa type I restriction enzyme n.s. ●●○○○ -1.05 -1.04890258198003
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1126  WP_009882704.1  A0A0H3PH13  clpA  709 aa AAA family ATPase n.s. ●●○○○ -1.05 -1.04833045193
Escherichia coli CFT073  c0655  AAN79130.1  A0A0H2V519  nfrB  720 aa Bacteriophage N4 adsorption protein B n.s. ●●○○○ -1.05 -1.04786144406431
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0685  CBW16784.1  A0A0H3NJ21  kdpD  894 aa sensor protein KdpD n.s. ●●○○○ -1.05 -1.04770580604228
Escherichia coli CFT073  c1445  AAN79914.1  A0A0H2V7G5  642 aa Putative DNA packaging protein of prophage; terminase large subunit n.s. ●●○○○ -1.05 -1.04719529562061
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4146  CBW20234.1  A0A0H3NVB6  784 aa bacteriophage tail protein n.s. ●●○○○ -1.05 -1.04691626474113
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