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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3926  AIK82474.1  523 aa galactarate dehydratase <1e-323 ●○○○○ -0.25 -0.248530692229929
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5149  AIK83670.1  204 aa ead/Ea22-like family protein <1e-323 ●○○○○ -0.25 -0.248431130987133
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1666  AIK80286.1  313 aa iaaA 0.001 ●○○○○ -0.25 -0.247949352755589
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4363  AIK82906.1  647 aa ABC transporter, substrate-binding, aliphatic sulfonates family protein 8.8e-7 ●○○○○ -0.25 -0.247887672425625
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4255  AIK82800.1  231 aa oligogalacturonate-specific porin family protein <1e-323 ●○○○○ -0.25 -0.247231727654808
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4212  AIK82757.1  299 aa bacterial regulatory helix-turn-helix, lysR family protein 1.2e-9 ●○○○○ -0.25 -0.246388397108898
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3376  AIK81933.1  184 aa putative dNA-damage-inducible protein D 6.6e-10 ●○○○○ -0.25 -0.24635936689449
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1836  AIK80449.1  554 aa asparagine synthase 1.1e-16 ●○○○○ -0.25 -0.246047411335547
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3969  AIK82517.1  257 aa siderophore-interacting FAD-binding domain protein <1e-323 ●○○○○ -0.25 -0.245014389090511
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5180  AIK83701.1  117 aa hypothetical protein 7.1e-8 ●○○○○ -0.24 -0.244790514929332
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3286  AIK81847.1  127 aa PIN domain protein <1e-323 ●○○○○ -0.24 -0.244702173163797
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4783  AIK83311.1  160 aa cupin domain protein 0.033 ●○○○○ -0.24 -0.244230193839773
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2160  AIK80765.1  264 aa ubiquinol oxidase, subunit II 0.013 ●○○○○ -0.24 -0.244017645017321
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4026  AIK82573.1  210 aa ADP-ribose pyrophosphatase 1.6e-10 ●○○○○ -0.24 -0.243645812570849
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4446  AIK82989.1  685 aa fhlA transcriptional activator 0.015 ●○○○○ -0.24 -0.243529563942441
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3616  AIK82171.1  263 aa nickel import ATP-binding protein NikE 1.3e-5 ●○○○○ -0.24 -0.242909090446592
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3036  AIK81621.1  162 aa cupin domain protein 0.012 ●○○○○ -0.24 -0.242187944835876
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3521  AIK82077.1  394 aa L-lactate dehydrogenase <1e-323 ●○○○○ -0.24 -0.240736531459168
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3017  AIK81602.1  807 aa outer membrane assembly complex, YaeT protein <1e-323 ●○○○○ -0.24 -0.239111426170161
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3476  AIK82032.1  352 aa methylated-DNA-cysteine S-methyltransferase family protein 2.5e-5 ●○○○○ -0.24 -0.236010703960854
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3221  AIK81782.1  612 aa tonB-dependent vitamin B12 receptor <1e-323 ●○○○○ -0.24 -0.235758587858308
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5093  AIK83619.1  77 aa hypothetical protein 0.011 ●○○○○ -0.23 -0.234074979636041
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3920  AIK82468.1  346 aa putative permease family protein 7.9e-9 ●○○○○ -0.23 -0.233727147257077
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4434  AIK82977.1  282 aa fecCD transport family protein <1e-323 ●○○○○ -0.23 -0.231290948224362
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3351  AIK81908.1  445 aa permease family protein 1.1e-16 ●○○○○ -0.23 -0.230414374909851
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3825  AIK82375.1  309 aa quorum sensing transcriptional regulator of LYSR-type <1e-323 ●○○○○ -0.23 -0.228243792486356
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5086  AIK83612.1  227 aa virB8 family protein 6.0e-6 ●○○○○ -0.23 -0.227880414762346
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2564  AIK81161.1  434 aa sugar (and other) transporter family protein 8.9e-16 ●○○○○ -0.23 -0.227372806326693
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2980  AIK81565.1  313 aa periplasmic binding and sugar binding domain of LacI family protein 1.9e-6 ●○○○○ -0.23 -0.226057291683834
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1971  AIK80577.1  345 aa oligopeptide/dipeptide ABC transporter, ATP-binding, C-terminal domain protein 1.6e-12 ●○○○○ -0.22 -0.224756773381845
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2687  AIK81281.1  494 aa heme ABC exporter, ATP-binding protein CcmA <1e-323 ●○○○○ -0.22 -0.222424643955918
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2849  AIK81438.1  212 aa methionine sulfoxide reductase A <1e-323 ●○○○○ -0.22 -0.222349491325403
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3075  AIK81660.1  1227 aa methionine synthase <1e-323 ●○○○○ -0.22 -0.221987659166574
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2667  AIK81261.1  456 aa aldehyde dehydrogenase family protein 6.2e-8 ●○○○○ -0.22 -0.221975988594115
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4089  AIK82635.1  379 aa radical SAM superfamily protein 0.0051 ●○○○○ -0.22 -0.22161181696359
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2147  AIK80752.1  133 aa acyl-CoA thioester hydrolase, YbgC/YbaW family protein 0.001 ●○○○○ -0.22 -0.218003443049242
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4094  AIK82640.1  326 aa putative transporter <1e-323 ●○○○○ -0.22 -0.216829066197454
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4044  AIK82591.1  299 aa bacterial regulatory helix-turn-helix, AraC family protein 3.5e-8 ●○○○○ -0.21 -0.214761040974317
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2176  AIK80781.1  303 aa putative 2-dehydropantoate 2-reductase 5.6e-14 ●○○○○ -0.21 -0.212856399785086
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2883  AIK81471.1  95 aa hypothetical protein 3.4e-5 ●○○○○ -0.21 -0.211019697674168
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2112  AIK80716.1  156 aa sigma70 sigma factor YlaC family protein 0.0016 ●○○○○ -0.21 -0.209641903503345
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4065  AIK82612.1  382 aa cystathionine beta-lyase 0.026 ●○○○○ -0.21 -0.20861141532973
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3456  AIK82012.1  400 aa sodium/glutamate symporter 1.5e-12 ●○○○○ -0.21 -0.207159605243245
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3651  AIK82206.1  308 aa branched-chain amino acid transport system / permease component family protein <1e-323 ●○○○○ -0.21 -0.206622059898253
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3538  AIK82094.1  513 aa heme ABC exporter, ATP-binding protein CcmA 1.4e-11 ●○○○○ -0.21 -0.206041448500959
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4226  AIK82771.1  470 aa EAL domain protein 4.7e-6 ●○○○○ -0.2 -0.204650263934339
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2661  AIK81255.1  271 aa putative ascBF operon repressor 9.9e-8 ●○○○○ -0.2 -0.203937538168053
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4205  AIK82750.1  127 aa crcB-like family protein 5.8e-8 ●○○○○ -0.2 -0.203646944429536
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3159  AIK81731.1  286 aa phospholipase A <1e-323 ●○○○○ -0.2 -0.203472356067588
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3534  AIK82090.1  610 aa alpha amylase, catalytic domain protein <1e-323 ●○○○○ -0.2 -0.203288070214936
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3356  AIK81913.1  139 aa hypothetical protein 1.3e-11 ●○○○○ -0.2 -0.203115292778114
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3426  AIK81983.1  1035 aa acrB RND-type permease <1e-323 ●○○○○ -0.2 -0.20241100675378
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1092  AIK79715.1  530 aa impA-related N-terminal family protein 1.0e-10 ●○○○○ -0.2 -0.201595971268788
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3158  AIK81730.1  608 aa ATP-dependent DNA helicase RecQ 9.4e-5 ●○○○○ -0.2 -0.199003681887632
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4921  AIK83447.1  393 aa setB MFS transporter 0.0019 ●○○○○ -0.2 -0.19842433551091
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1673  AIK80292.1  421 aa putative cytoplasmic protein 0.00063 ●○○○○ -0.2 -0.197245707454476
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4177  AIK82722.1  1214 aa evgS-Phis <1e-323 ●○○○○ -0.2 -0.196398194307851
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2547  AIK81144.1  234 aa dpiA-phosphorylated DNA binding transcriptional dual regulator 0.0035 ●○○○○ -0.2 -0.196219670857245
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1998  AIK80604.1  187 aa hypothetical protein 9.2e-5 ●○○○○ -0.2 -0.196047602319969
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1826  AIK80439.1  147 aa sugar (and other) transporter family protein 0.00017 ●○○○○ -0.2 -0.195718817510035
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1390  AIK80013.1  186 aa hypothetical protein 8.6e-6 ●○○○○ -0.2 -0.19552523077487
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4336  AIK82881.1  264 aa cbiX family protein 1.1e-9 ●○○○○ -0.2 -0.195331469732288
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4003  AIK82550.1  567 aa urease, alpha subunit 7.6e-5 ●○○○○ -0.19 -0.193328748226659
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3856  AIK82406.1  338 aa zinc-binding dehydrogenase family protein <1e-323 ●○○○○ -0.19 -0.191193512969223
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3575  AIK82130.1  267 aa cellulose synthase operon protein YhjQ <1e-323 ●○○○○ -0.19 -0.189284522221124
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3240  AIK81801.1  518 aa hypothetical protein <1e-323 ●○○○○ -0.19 -0.188913118993808
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3451  AIK82007.1  459 aa 4 glycosyl hydrolase family protein <1e-323 ●○○○○ -0.19 -0.187799124154907
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3787  AIK82342.1  374 aa DNA protecting protein DprA <1e-323 ●○○○○ -0.19 -0.18772262482369
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3265  AIK81826.1  419 aa L-rhamnose isomerase 5.7e-15 ●○○○○ -0.19 -0.185437999873227
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2604  AIK81201.1  342 aa 16S rRNA m2G1207 methyltransferase 7.4e-8 ●○○○○ -0.18 -0.184397323663286
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3152  AIK81724.1  299 aa carboxylate/amino acid/amine transporter family protein <1e-323 ●○○○○ -0.18 -0.183908829658566
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3474  AIK82030.1  205 aa hypothetical protein <1e-323 ●○○○○ -0.18 -0.183532367196751
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2651  AIK81245.1  254 aa 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase <1e-323 ●○○○○ -0.18 -0.182888531669952
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1057  AIK79680.1  374 aa outer membrane protein C 1.3e-6 ●○○○○ -0.18 -0.181980861858626
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2671  AIK81265.1  426 aa hypothetical protein <1e-323 ●○○○○ -0.18 -0.181612330129679
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3835  AIK82385.1  221 aa bacterial regulatory, gntR family protein 2.7e-10 ●○○○○ -0.18 -0.180770683500184
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3454  AIK82010.1  463 aa xanP xanthine NCS2 transporter 2.0e-14 ●○○○○ -0.18 -0.180750134590811
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2422  AIK81019.1  238 aa sugar fermentation stimulation protein 0.016 ●○○○○ -0.18 -0.180040508082007
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2995  AIK81580.1  741 aa type VII secretion system (T7SS), usher family protein <1e-323 ●○○○○ -0.18 -0.179929156429244
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3633  AIK82188.1  221 aa conserved hypothetical integral membrane family protein <1e-323 ●○○○○ -0.18 -0.179647325052008
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4435  AIK82978.1  273 aa ABC transporter family protein 1.1e-6 ●○○○○ -0.18 -0.178639020367784
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2229  AIK80834.1  471 aa alkaline phosphatase H 5.7e-5 ●○○○○ -0.18 -0.178216637684752
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5116  AIK83642.1  673 aa tonB-dependent siderophore receptor family protein 9.1e-5 ●○○○○ -0.18 -0.177937606337551
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3155  AIK81727.1  206 aa homoserine/Threonine efflux family protein 0.0032 ●○○○○ -0.18 -0.177244173620906
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2732  AIK81322.1  37 aa hypothetical protein 0.029 ●○○○○ -0.17 -0.17192703147578
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3289  AIK81850.1  313 aa hypothetical protein <1e-323 ●○○○○ -0.17 -0.171655828807791
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1946  AIK80552.1  201 aa hypothetical protein 0.0068 ●○○○○ -0.17 -0.169704648999804
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3722  AIK82276.1  304 aa amidohydrolase family protein 4.2e-14 ●○○○○ -0.17 -0.168749618538259
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3536  AIK82092.1  392 aa bacterial regulatory helix-turn-helix, AraC family protein <1e-323 ●○○○○ -0.17 -0.168301362141447
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4713  AIK83247.1  318 aa transaldolase 9.0e-13 ●○○○○ -0.17 -0.167552787887593
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2019  AIK80625.1  312 aa aldo/keto reductase family protein 2.0e-9 ●○○○○ -0.17 -0.167136604121903
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4661  AIK83195.1  78 aa hypothetical protein 8.1e-8 ●○○○○ -0.17 -0.166014087114177
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3565  AIK82121.1  551 aa sulfatase family protein <1e-323 ●○○○○ -0.16 -0.164785421186935
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3833  AIK82383.1  312 aa malate dehydrogenase, NAD-dependent 0.00024 ●○○○○ -0.16 -0.164654813231194
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4673  AIK83207.1  335 aa hypothetical protein 2.1e-15 ●○○○○ -0.16 -0.164653958802882
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3222  AIK81783.1  366 aa tRNA (uracil-5-)-methyltransferase 3.3e-16 ●○○○○ -0.16 -0.164063738649089
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3963  AIK82511.1  332 aa branched-chain amino acid transport system / permease component family protein 3.8e-9 ●○○○○ -0.16 -0.163522186698957
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4233  AIK82778.1  182 aa fimbrial subunit type 1 0.0041 ●○○○○ -0.16 -0.163105106903003
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3347  AIK81904.1  515 aa lamB porin family protein <1e-323 ●○○○○ -0.16 -0.162235721120821
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2811  AIK81400.1  315 aa trehalose operon repressor 5.4e-8 ●○○○○ -0.16 -0.161324715755596
Retrieved entries 901–1,000 out of 3,098 total in 134.3 ms (Link to these results)