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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4824  AIK83351.1  212 aa glutathione S-transferase, N-terminal domain protein 0.00053 ○○○○○ 0.78 0.78218250675231
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2010  AIK80616.1  119 aa helix-turn-helix family protein 3.5e-10 ○○○○○ 0.78 0.783140950339769
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1720  AIK80340.1  170 aa molybdenum cofactor biosynthesis protein B 2.5e-6 ○○○○○ 0.78 0.783370684101584
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4499  AIK83038.1  558 aa 2-isopropylmalate synthase 3.2e-6 ○○○○○ 0.79 0.785105252329763
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4949  AIK83475.1  189 aa conserved inner membrane protein 0.008 ○○○○○ 0.79 0.785123732219516
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1053  AIK79676.1  146 aa heat shock protein hslJ 1.1e-7 ○○○○○ 0.79 0.788609600025073
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1980  AIK80586.1  879 aa HAD ATPase, P-type, IC family protein <1e-323 ○○○○○ 0.79 0.789463194270971
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4554  AIK83092.1  190 aa flavin reductase domain protein, FMN-binding protein 0.00049 ○○○○○ 0.79 0.78965193587335
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5061  AIK83587.1  318 aa bacterial regulatory helix-turn-helix, lysR family protein 0.013 ○○○○○ 0.79 0.790813091458572
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3916  AIK82463.1  163 aa acetyltransferase family protein 8.6e-6 ○○○○○ 0.79 0.791485554775801
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4998  AIK83524.1  1025 aa MMPL family protein <1e-323 ○○○○○ 0.79 0.792821821877197
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1725  AIK80345.1  365 aa HAMP domain protein 3.8e-6 ○○○○○ 0.79 0.793873122196335
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2769  AIK81358.1  339 aa zinc-binding dehydrogenase family protein 0.0019 ○○○○○ 0.8 0.795717862292235
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2339  AIK80942.1  251 aa hydroxyacylglutathione hydrolase 2.2e-12 ○○○○○ 0.8 0.79737938147429
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3004  AIK81589.1  222 aa glutathione S-transferase, C-terminal domain protein <1e-323 ○○○○○ 0.8 0.798897429170345
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1481  AIK80102.1  511 aa EAL domain protein <1e-323 ○○○○○ 0.8 0.8033003838332
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1353  AIK79976.1  313 aa putative L,D-transpeptidase YcfS 7.7e-5 ○○○○○ 0.8 0.803652485517907
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5137  AIK83661.1  544 aa na+/H+ antiporter <1e-323 ○○○○○ 0.8 0.80451499316205
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2034  AIK80640.1  505 aa sucrose porin <1e-323 ○○○○○ 0.81 0.805870023821511
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1204  AIK79827.1  276 aa putative alcohol dehydrogenase zinc-binding domain protein 0.0012 ○○○○○ 0.81 0.805933186293334
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2530  AIK81127.1  621 aa kefC potassium CPA2 transporter <1e-323 ○○○○○ 0.81 0.807693120578357
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1812  AIK80424.1  492 aa dipeptide permease D <1e-323 ○○○○○ 0.81 0.811229209649842
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1655  AIK80275.1  400 aa penicillin-binding protein 6 <1e-323 ○○○○○ 0.81 0.812861668657827
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4622  AIK83156.1  445 aa response regulator 0.00042 ○○○○○ 0.81 0.81402596306855
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5005  AIK83531.1  618 aa his Kinase A domain protein <1e-323 ○○○○○ 0.82 0.815532233024808
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1301  AIK79924.1  502 aa 3-octaprenyl-4-hydroxybenzoate carboxy-lyase family protein 0.0018 ○○○○○ 0.82 0.816551188005763
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3386  AIK81943.1  307 aa D-serine deaminase transcriptional activator <1e-323 ○○○○○ 0.82 0.819970015331173
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1658  AIK80278.1  369 aa aldose sugar dehydrogenase 7.3e-7 ○○○○○ 0.82 0.82160237329614
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1437  AIK80059.1  212 aa rutR transcriptional dual regulator <1e-323 ○○○○○ 0.82 0.823394023509822
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4220  AIK82765.1  482 aa putative outer membrane factor of efflux pump 6.7e-16 ○○○○○ 0.82 0.82392502239927
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1046  AIK79669.1  499 aa feaB 5.9e-5 ○○○○○ 0.82 0.824164694645049
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5126  AIK83652.1  434 aa salicylate synthase 4.4e-16 ○○○○○ 0.83 0.825431298793595
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1639  AIK80259.1  283 aa DNA adenine methylase family protein <1e-323 ○○○○○ 0.83 0.826037328804341
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1060  AIK79682.1  141 aa hypothetical protein 0.006 ○○○○○ 0.83 0.826134321101349
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2138  AIK80743.1  428 aa amtB ammonium Amt transporter AmtB <1e-323 ○○○○○ 0.83 0.828689280646926
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1601  AIK80221.1  281 aa potI 0.0038 ○○○○○ 0.84 0.835561228755714
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2922  AIK81508.1  428 aa hlyD secretion family protein 6.1e-6 ○○○○○ 0.84 0.838357200052019
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1328  AIK79951.1  373 aa cupin superfamily protein <1e-323 ○○○○○ 0.84 0.839377355789312
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3029  AIK81614.1  237 aa class B acid phosphatase 1.9e-9 ○○○○○ 0.84 0.840697514864528
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2816  AIK81405.1  91 aa PTS system, Lactose/Cellobiose specific IIB subunit 1.4e-9 ○○○○○ 0.84 0.841592216912318
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4961  AIK83487.1  239 aa response regulator 9.5e-6 ○○○○○ 0.84 0.842260302487849
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2550  AIK81147.1  304 aa inosine-uridine preferring nucleoside hydrolase family protein 4.9e-9 ○○○○○ 0.84 0.844474146538163
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1266  AIK79889.1  248 aa scaffolding protein that interacts with murein polymerase and murein hydrolase 1.1e-9 ○○○○○ 0.84 0.844975350591811
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4690  AIK83224.1  401 aa uracil-xanthine permease family protein <1e-323 ○○○○○ 0.85 0.84766739438604
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4238  AIK82784.1  168 aa marR family protein 6.2e-7 ○○○○○ 0.85 0.847785043181042
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4986  AIK83512.1  218 aa HAD hydrolase, IA, variant 1 family protein 3.4e-15 ○○○○○ 0.85 0.848191441020823
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2772  AIK81361.1  274 aa phosphohydrolase 2.9e-14 ○○○○○ 0.85 0.848642522910036
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1517  AIK80137.1  263 aa ssuC 0.02 ○○○○○ 0.85 0.849440670831761
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4924  AIK83450.1  564 aa PTS system, Fru family, IIB component domain protein <1e-323 ○○○○○ 0.85 0.851420908069461
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2334  AIK80938.1  293 aa bacterial regulatory helix-turn-helix, lysR family protein 6.8e-8 ○○○○○ 0.85 0.851659027368733
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4757  AIK83291.1  308 aa bacterial regulatory helix-turn-helix, lysR family protein <1e-323 ○○○○○ 0.85 0.852675790809091
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3028  AIK81613.1  138 aa hypothetical protein <1e-323 ○○○○○ 0.86 0.857854602787652
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4689  AIK83223.1  208 aa uracil phosphoribosyltransferase 2.2e-10 ○○○○○ 0.86 0.859222871049139
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4584  AIK83122.1  233 aa hypothetical protein <1e-323 ○○○○○ 0.86 0.863546503252402
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1050  AIK79673.1  879 aa dicarboxylate transport family protein 7.7e-6 ○○○○○ 0.86 0.864285624549153
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4745  AIK83279.1  279 aa pyridoxal kinase 3.6e-14 ○○○○○ 0.87 0.867414686397077
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4184  AIK82729.1  197 aa ABC transporter family protein <1e-323 ○○○○○ 0.87 0.868198405140005
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1716  AIK80336.1  214 aa inhibitor of apoptosis-promoting Bax1 family protein 1.5e-11 ○○○○○ 0.87 0.868364221766892
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1179  AIK79802.1  890 aa aconitate hydratase 1 <1e-323 ○○○○○ 0.87 0.869510997460645
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1308  AIK79931.1  468 aa bacterial Cytochrome Ubiquinol Oxidase family protein 0.039 ○○○○○ 0.87 0.871358067184888
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2817  AIK81406.1  247 aa helix-turn-helix domain, rpiR family protein <1e-323 ○○○○○ 0.87 0.871845131794102
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1347  AIK79970.1  303 aa N-acetyl-D-glucosamine kinase <1e-323 ○○○○○ 0.87 0.87200139088682
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2742  AIK81332.1  449 aa PLD-like domain protein <1e-323 ○○○○○ 0.87 0.87221955187266
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1881  AIK80487.1  142 aa universal stress protein UP12 <1e-323 ○○○○○ 0.87 0.873616934578837
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1467  AIK80088.1  833 aa fused predicted PTS system enzymes: Hpr component, enzyme I component, enzyme IIA component 1.2e-12 ○○○○○ 0.87 0.874176596029458
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1675  AIK80295.1  787 aa glycosyl hydrolases 31 family protein <1e-323 ○○○○○ 0.88 0.878131227162297
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1580  AIK80200.1  550 aa hydroxylamine reductase <1e-323 ○○○○○ 0.88 0.880614442409697
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2018  AIK80624.1  263 aa protein moaF <1e-323 ○○○○○ 0.88 0.881578298212719
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4084  AIK82630.1  108 aa hypothetical protein 8.9e-14 ○○○○○ 0.88 0.8816198355855
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3260  AIK81821.1  206 aa superoxide dismutase (Mn) <1e-323 ○○○○○ 0.88 0.881770245633652
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3936  AIK82484.1  298 aa bacterial regulatory helix-turn-helix, lysR family protein 0.00077 ○○○○○ 0.88 0.881781418956651
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4423  AIK82966.1  259 aa hemin import ATP-binding protein HmuV 3.5e-11 ○○○○○ 0.88 0.882187160212401
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1571  AIK80191.1  759 aa ATP-dependent Clp protease ATP-binding subunit ClpA 4.9e-9 ○○○○○ 0.88 0.883902992935541
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1014  AIK79637.1  488 aa succinylglutamic semialdehyde dehydrogenase 4.4e-11 ○○○○○ 0.88 0.884478888930841
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5092  AIK83618.1  71 aa transglycosylase SLT domain protein 0.0096 ○○○○○ 0.89 0.885857443400145
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1509  AIK80129.1  630 aa heme ABC exporter, ATP-binding protein CcmA <1e-323 ○○○○○ 0.89 0.888360282507454
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1099  AIK79722.1  573 aa type VI secretion valine-glycine repeat protein G 1.1e-7 ○○○○○ 0.89 0.888640064831251
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1068  AIK79691.1  459 aa amino acid permease family protein <1e-323 ○○○○○ 0.89 0.889667763757723
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3427  AIK81984.1  374 aa efflux transporter, RND family, MFP subunit <1e-323 ○○○○○ 0.89 0.890141741548051
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3542  AIK82098.1  123 aa conserved inner membrane protein <1e-323 ○○○○○ 0.89 0.892596505878281
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1730  AIK80350.1  385 aa 8-amino-7-oxononanoate synthase <1e-323 ○○○○○ 0.89 0.893814913108823
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1012  AIK79635.1  331 aa succinylglutamate desuccinylase <1e-323 ○○○○○ 0.9 0.89689794906848
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2499  AIK81096.1  404 aa major Facilitator Superfamily protein <1e-323 ○○○○○ 0.9 0.898369210105333
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2800  AIK81389.1  334 aa ornithine carbamoyltransferase <1e-323 ○○○○○ 0.9 0.898773362994058
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3367  AIK81924.1  247 aa 2-oxo-3-deoxygalactonate kinase <1e-323 ○○○○○ 0.9 0.899642304722584
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1924  AIK80530.1  535 aa (2,3-dihydroxybenzoyl)adenylate synthase <1e-323 ○○○○○ 0.9 0.899767378296354
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4995  AIK83521.1  240 aa transcriptional regulatory, C terminal family protein 1.4e-6 ○○○○○ 0.9 0.901663905889434
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4313  AIK82858.1  210 aa propanediol utilization PduL family protein <1e-323 ○○○○○ 0.9 0.903113016856243
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4484  AIK83027.1  159 aa competence/damage-inducible CinA C-terminal domain protein 6.0e-11 ○○○○○ 0.9 0.903614732949791
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3535  AIK82091.1  187 aa mannosyl-glycoendo-beta-N-acetylglucosaminidase family protein 9.7e-6 ○○○○○ 0.91 0.9092506306004
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4246  AIK82791.1  211 aa fimbrial family protein <1e-323 ○○○○○ 0.91 0.911116093110975
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1604  AIK80224.1  370 aa potF 1.7e-11 ○○○○○ 0.91 0.913814905397742
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1424  AIK80045.1  60 aa hypothetical protein 1.7e-6 ○○○○○ 0.91 0.914403717589054
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1482  AIK80103.1  112 aa anti-anti-sigma factor family protein 1.2e-8 ○○○○○ 0.91 0.91444128206252
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2140  AIK80745.1  592 aa ABC transporter family protein <1e-323 ○○○○○ 0.92 0.915819390321343
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5089  AIK83615.1  203 aa type IV secretion system family protein 1.1e-16 ○○○○○ 0.92 0.916183271628527
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4853  AIK83380.1  556 aa 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase 7.8e-11 ○○○○○ 0.92 0.916322589483699
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5051  AIK83577.1  474 aa exonuclease I, 3' -- 5' specific deoxyribophosphodiesterase <1e-323 ○○○○○ 0.92 0.920726438136712
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1828  AIK80441.1  467 aa outer membrane porin, OprD family protein <1e-323 ○○○○○ 0.92 0.921035346145188
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1810  AIK80423.1  247 aa conserved metal-binding protein 0.0041 ○○○○○ 0.92 0.921590523852864
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