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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1538  WP_000217087.1  E8XIA7  315 aa hypothetical protein 0.041 ○○○○○ 1.27 1.26927180841504
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4582  WP_000776531.1  E8XAR0  ptxA  154 aa PTS ascorbate transporter subunit IIA 0.0025 ○○○○○ 1.27 1.27027193378909
Escherichia coli M12  CO715_02735  ATI04748.1  292 aa 4-hydroxy-tetrahydrodipicolinate synthase 5.3e-28 ○○○○○ 1.27 1.27053609199003
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4039  AIK82586.1  470 aa cell division protein <1e-323 ○○○○○ 1.27 1.27064346106542
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1276  AIK79899.1  301 aa bacterial regulatory helix-turn-helix, lysR family protein <1e-323 ○○○○○ 1.27 1.2706920642517
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2478  WP_014343873.1  E8XF34  mnmC  686 aa bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC 0.00055 ○○○○○ 1.27 1.2708763709456
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1121  AIK79744.1  464 aa hypothetical protein <1e-323 ○○○○○ 1.27 1.2709906364804
Acinetobacter baumannii ATCC 17978  A1S_0485  ABO10940.2  447 aa high-affinity gluconate permease (GntP family) 1.0e-7 ○○○○○ 1.27 1.27211678605533
Escherichia coli M12  CO715_15025  ATI06910.1  231 aa lactate utilization protein C 0.0056 ○○○○○ 1.27 1.27241390611827
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4002  AIK82549.1  158 aa urease accessory protein ureE <1e-323 ○○○○○ 1.27 1.27401886878225
Escherichia coli M12  CO715_08400  ATI08767.1  337 aa hypothetical protein 4.9e-11 ○○○○○ 1.28 1.277212764446
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1508  WP_000705294.1  E8XI78  ynff  811 aa dimethyl sulfoxide reductase subunit A 0.00037 ○○○○○ 1.28 1.27723373557114
Streptococcus pyogenes M1 5448  SP5448_02410  WP_002988786.1  1460 aa tape measure protein 0.041 ○○○○○ 1.28 1.2774396476091
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1067  AIK79690.1  248 aa hypothetical protein 3.4e-9 ○○○○○ 1.28 1.28024837931241
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1342  AIK79965.1  335 aa 4-hydroxythreonine-4-phosphate dehydrogenase 9.4e-14 ○○○○○ 1.28 1.28125015843457
Escherichia coli M12  CO715_09375  ATI05903.1  169 aa hypothetical protein 1.0e-25 ○○○○○ 1.28 1.28138568473097
Escherichia coli M12  CO715_13015  ATI06546.1  188 aa 3-deoxy-manno-octulosonate-8-phosphatase KdsC 6.1e-13 ○○○○○ 1.28 1.28180297675947
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1465  AIK80086.1  482 aa succinate-semialdehyde dehydrogenase family protein <1e-323 ○○○○○ 1.28 1.28289236732077
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4952  AIK83478.1  184 aa acetyltransferase family protein <1e-323 ○○○○○ 1.28 1.28374631193047
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4607  WP_000060815.1  E8XAT5  ytfN  1259 aa autotransporter assembly complex protein TamB 0.012 ○○○○○ 1.28 1.28444981824907
Acinetobacter baumannii ATCC 17978  A1S_1884  ABO12311.2  209 aa protocatechuate 34-dioxygenase alpha chain (3,4-PCD) 2.6e-5 ○○○○○ 1.29 1.28631530764216
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0953  WP_000534681.1  E8XCS3  dmsC  287 aa dimethyl sulfoxide reductase anchor subunit 0.003 ○○○○○ 1.29 1.28677769946239
Escherichia coli M12  CO715_17710  ATI07392.1  396 aa PrgH/EprH family type III secretion apparatus protein 2.1e-48 ○○○○○ 1.29 1.28722777312994
Escherichia coli M12  CO715_24640  ATI08615.1  378 aa hypothetical protein 1.7e-14 ○○○○○ 1.29 1.28743641914419
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1773  WP_001191156.1  E8XKX3  purU  280 aa formyltetrahydrofolate deformylase 0.0038 ○○○○○ 1.29 1.28774356720214
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1297  CBW17393.1  A0A0H3NAV0  ydiL  119 aa Conserved hypothetical protein 0.0057 ○○○○○ 1.29 1.28881888002603
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0192  CBW16294.1  A0A0H3N852  fhuA  729 aa ferrichrome-iron receptor 0.011 ○○○○○ 1.29 1.29071424562486
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1759  AIK80379.1  257 aa molybdate ABC transporter, periplasmic molybdate-binding protein 1.4e-15 ○○○○○ 1.29 1.29084394267305
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0908  NP_233293.2  Q9KL40  hutX  167 aa hypothetical protein 0.0019 ○○○○○ 1.29 1.29107595189823
Escherichia coli M12  CO715_07710  ATI05610.1  461 aa IS66 family transposase 0.0079 ○○○○○ 1.29 1.29140069341492
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0433  NP_230087.1  Q9KUT2  468 aa arginine/ornithine antiporter 0.0025 ○○○○○ 1.29 1.29300088013957
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3123  WP_000806780.1  E8X8R2  fucK  472 aa L-fuculokinase 0.0076 ○○○○○ 1.29 1.29367271996771
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1281  AIK79904.1  53 aa hypothetical protein 3.0e-10 ○○○○○ 1.29 1.29445410550849
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1919  AIK80524.1  134 aa helix-turn-helix family protein 1.2e-15 ○○○○○ 1.29 1.29447344563593
Escherichia coli M12  CO715_24285  ATI08554.1  159 aa type VI secretion system tube protein Hcp 6.8e-36 ○○○○○ 1.29 1.2947390296429
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3227  CBW19323.1  A0A0H3NS73  304 aa hypothetical fructose-1-phosphate kinase 0.0033 ○○○○○ 1.3 1.29669096501728
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3919  AIK82467.1  215 aa hypothetical protein <1e-323 ○○○○○ 1.3 1.29848826186655
Escherichia coli M12  CO715_01280  ATI04484.1  91 aa hypothetical protein 1.5e-5 ○○○○○ 1.3 1.29849465789938
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0812  WP_001249472.1  E8XBQ0  hutI  407 aa imidazolonepropionase 0.0067 ○○○○○ 1.3 1.29870375686946
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2953  WP_001187300.1  E8XK59  emrB  512 aa multidrug efflux MFS transporter permease subunit EmrB 0.00051 ○○○○○ 1.3 1.29911506243865
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3846  WP_000074065.1  E8XFY8  lyxK  498 aa carbohydrate kinase 0.0043 ○○○○○ 1.3 1.29933244602351
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2535  CBW18635.1  A0A0H3NEE1  288 aa hypothetical oxidoreductase 0.015 ○○○○○ 1.3 1.29964144029659
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2613  AIK81207.1  152 aa ybaK / prolyl-tRNA synthetases associated domainprotein 9.0e-12 ○○○○○ 1.3 1.30186798940912
Escherichia coli M12  CO715_16420  ATI07158.1  500 aa L-arabinose isomerase 1.7e-83 ○○○○○ 1.3 1.30433674629835
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4005  WP_000704735.1  E8XHR4  dgoA  382 aa galactonate dehydratase 0.0081 ○○○○○ 1.3 1.30488587302946
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1618  WP_001238501.1  E8XJ53  392 aa benzoate/H(+) symporter BenE family transporter 0.0028 ○○○○○ 1.31 1.30788677729468
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3799  WP_001196509.1  E8XFU4  dppD  327 aa dipeptide ABC transporter ATP-binding protein 0.021 ○○○○○ 1.31 1.30824758106506
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4030  WP_001214973.1  E8XHT9  yicO  487 aa NCS2 family permease 0.0041 ○○○○○ 1.31 1.30902537845878
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0994  CBW17090.1  99 aa predicted bacteriophage protein (pseudogene) 0.023 ○○○○○ 1.31 1.30937219240736
Escherichia coli M12  CO715_21675  ATI08107.1  666 aa hypothetical protein 8.4e-49 ○○○○○ 1.31 1.31017883469732
Acinetobacter baumannii ATCC 17978  A1S_0673  ABO11121.1  216 aa putative transposase 0.033 ○○○○○ 1.31 1.31050051678584
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1597  AIK80217.1  283 aa sensory transduction histidine kinase domain protein 3.9e-6 ○○○○○ 1.31 1.31178793158225
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3739  WP_000743277.1  E8XF84  rsmD  198 aa 16S rRNA (guanine(966)-N(2))-methyltransferase 0.0093 ○○○○○ 1.31 1.31194081234903
Escherichia coli M12  CO715_17410  ATI07340.1  243 aa l-fucose operon activator 2.8e-14 ○○○○○ 1.31 1.3122652948398
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2138  WP_000100782.1  E8XC07  pduS  451 aa cobalamin reductase PduS 0.0073 ○○○○○ 1.31 1.31235983960883
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2842  WP_000059178.1  E8XJ68  217 aa terminase endonuclease subunit 0.0016 ○○○○○ 1.31 1.31380811956682
Streptococcus pyogenes M1 5448  SP5448_05270  WP_002984660.1  150 aa GNAT family N-acetyltransferase 0.047 ○○○○○ 1.31 1.31397043453556
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1662  AIK80282.1  303 aa N-terminal TM domain of oligopeptide transport permease C family protein 1.5e-5 ○○○○○ 1.31 1.3148679491567
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5084  AIK83610.1  416 aa bacterial conjugation TrbI-like family protein <1e-323 ○○○○○ 1.31 1.31488272562256
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0409  NP_230063.1  H9L4Q5  178 aa MSHA pilin protein MshA 0.00076 ○○○○○ 1.32 1.31614774112412
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1455  AIK80076.1  463 aa putrescine importer <1e-323 ○○○○○ 1.32 1.31637565457069
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1151  AIK79775.1  463 aa major Facilitator Superfamily protein 1.6e-9 ○○○○○ 1.32 1.31697676793728
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2003  CBW18099.1  A0A0H3ND61  cbiH  241 aa precorrin-3 C17-methyltransferase 0.0061 ○○○○○ 1.32 1.31811732228954
Escherichia coli M12  CO715_11775  ATI06324.1  193 aa esterase YqiA 0.03 ○○○○○ 1.32 1.3220716575095
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1094  NP_233474.1  Q9KKL0  175 aa purine-binding chemotaxis protein CheW 3.7e-5 ○○○○○ 1.32 1.32360832288611
Escherichia coli M12  CO715_01030  ATI04439.1  346 aa phosphate ABC transporter substrate-binding protein PstS 1.6e-9 ○○○○○ 1.32 1.32374082562349
Acinetobacter baumannii ATCC 17978  A1S_2225  ABO12652.2  156 aa hypothetical protein 0.0028 ○○○○○ 1.33 1.32511903718894
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3212  WP_000669854.1  E8X9N6  248 aa oxidative stress defense protein 0.0022 ○○○○○ 1.33 1.32513140941422
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0007  WP_000130175.1  E8XG27  talB  317 aa transaldolase 0.013 ○○○○○ 1.33 1.3251966581932
Porphyromonas gingivalis ATCC 33277  PGN_0340  WP_012457439.1  B2RHL4  533 aa S41 family peptidase 3.0e-7 ○○○○○ 1.33 1.32546641867022
Escherichia coli M12  CO715_21865  ATI08143.1  110 aa hypothetical protein 0.00023 ○○○○○ 1.33 1.32666186982298
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0983  NP_233367.1  Q9KKW7  582 aa L-lactate permease 3.4e-5 ○○○○○ 1.33 1.32877069134309
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4029  CBW20118.1  A0A0H3NK33  254 aa hypothetical ribulose-phosphate 3-epimerase 0.0022 ○○○○○ 1.33 1.3310459253505
Acinetobacter baumannii ATCC 17978  A1S_1719  ABO12146.1  81 aa 4Fe-4S ferredoxin iron-sulfur binding 0.0042 ○○○○○ 1.33 1.33129134339668
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1688  NP_231324.1  Q9KRF4  415 aa hypothetical protein 0.027 ○○○○○ 1.33 1.33191097500035
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0218  WP_000753958.1  E8XI07  htrA  475 aa serine endoprotease DegP 0.0021 ○○○○○ 1.33 1.33219906000025
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3943  WP_000093404.1  E8XGW7  285 aa PTS system mannose/fructose/sorbose family transporter subunit IID 0.0032 ○○○○○ 1.33 1.33264090491032
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4652  WP_001181297.1  E8XBK7  treR  315 aa HTH-type transcriptional regulator TreR 0.0071 ○○○○○ 1.33 1.33299129849777
Escherichia coli M12  CO715_12025  ATI06371.1  186 aa YtfJ family protein 8.2e-5 ○○○○○ 1.33 1.33312989626469
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2033  AIK80639.1  307 aa putative sugar kinase <1e-323 ○○○○○ 1.33 1.3335307322503
Escherichia coli M12  CO715_20490  ATI07892.1  199 aa molecular chaperone TorD 3.6e-5 ○○○○○ 1.33 1.33375583430744
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1702  AIK80322.1  281 aa transketolase, thiamine diphosphate binding domain protein <1e-323 ○○○○○ 1.34 1.33527325804908
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0895  WP_000661875.1  E8XCL7  206 aa TetR/AcrR family transcriptional regulator 0.0042 ○○○○○ 1.34 1.33536377845945
Porphyromonas gingivalis ATCC 33277  PGN_0036  WP_012457186.1  B2RGR0  87 aa hypothetical protein 0.00016 ○○○○○ 1.34 1.33556005675865
Escherichia coli M12  CO715_11725  ATI06315.1  223 aa protein-disulfide oxidoreductase DsbI 0.036 ○○○○○ 1.34 1.33563364843568
Escherichia coli M12  CO715_12640  ATI06477.1  256 aa 5-keto-4-deoxy-D-glucarate aldolase 2.5e-5 ○○○○○ 1.34 1.33667687850692
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4215  WP_010989087.1  E8XKA1  fdoG  1016 aa formate dehydrogenase-N subunit alpha 0.0078 ○○○○○ 1.34 1.3367726065973
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1371  AIK79994.1  269 aa aminodeoxychorismate lyase 0.0034 ○○○○○ 1.34 1.33760260030912
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0477  WP_001238163.1  E8XKP4  ybaE  566 aa SgrR family transcriptional regulator 0.0044 ○○○○○ 1.34 1.33956868690422
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4700  AIK83234.1  344 aa nlpB/DapX lipofamily protein <1e-323 ○○○○○ 1.34 1.34226456130434
Acinetobacter baumannii ATCC 17978  A1S_0626  ABO11075.2  299 aa hypothetical protein 4.5e-8 ○○○○○ 1.34 1.34363299004169
Acinetobacter baumannii ATCC 17978  A1S_0799  ABO11237.2  A3M2U3  ligA  678 aa DNA ligase 0.00019 ○○○○○ 1.34 1.34423182427484
Escherichia coli M12  CO715_01485  ATI04519.1  41 aa entericidin A 0.00021 ○○○○○ 1.34 1.34439678103413
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1671  AIK80291.1  271 aa HAD hydrolase, IIB family protein <1e-323 ○○○○○ 1.35 1.34602361744694
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2703  WP_000372065.1  E8XHH6  1031 aa phage tail tape measure protein 0.01 ○○○○○ 1.35 1.3461277097455
Escherichia coli M12  CO715_16725  ATI07216.1  143 aa carboxymuconolactone decarboxylase family protein 3.2e-13 ○○○○○ 1.35 1.34690053320512
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1258  CBW17354.1  A0A0H3NAZ9  yniB  178 aa hypothetical membrane protein 0.003 ○○○○○ 1.35 1.34962064273561
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4113  WP_000979262.1  E8XIP1  hemY  399 aa protoheme IX biogenesis protein HemY 0.0056 ○○○○○ 1.35 1.34990819161531
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1289  CBW17386.1  A0A0H3NCK5  ydiP  296 aa hypothetical HTH-type transcriptional regulator 0.0025 ○○○○○ 1.36 1.35520775842566
Escherichia coli M12  CO715_02670  ATI04735.1  670 aa hydrogenase 1.6e-46 ○○○○○ 1.36 1.35545501978932
Retrieved entries 34,901–35,000 out of 36,363 total in 849.9 ms (Link to these results)