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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3086  CBW19185.1  A0A0H3NFW8  yggX  91 aa conserved hypothetical protein n.s. ●○○○○ -0.8 -0.796817203629128
Mycobacterium avium subsp. paratuberculosis K10  MAP_3294  AAS05844.1  Q73US2  289 aa hypothetical protein n.s. ●○○○○ -0.8 -0.796610350536734
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0567  CBW16667.1  A0A0H3N9A1  ybdF  122 aa conserved hypothetical protein n.s. ●○○○○ -0.8 -0.796253134178721
Vibrio parahaemolyticus RIMD 2210633  VPA_1600  BAC62943.1  Q87FS8  213 aa hypothetical protein n.s. ●○○○○ -0.8 -0.796064092350174
Mycobacterium avium subsp. paratuberculosis K10  MAP_1658  AAS03975.1  Q73ZE5  512 aa hypothetical protein n.s. ●○○○○ -0.8 -0.795574463236694
Escherichia coli CFT073  c0483  AAN78961.1  A0A0H2V5F1  yaiW  364 aa Hypothetical protein yaiW n.s. ●○○○○ -0.8 -0.795392857770541
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4333  CBW20419.1  A0A0H3NJ48  ytfF  321 aa hypothetical membrane protein n.s. ●○○○○ -0.8 -0.795377605669067
Mycobacterium avium subsp. paratuberculosis K10  MAP_3946  AAS06496.1  Q73SX7  172 aa hypothetical protein n.s. ●○○○○ -0.8 -0.795291399088334
Streptococcus pyogenes M1 5448  SP5448_03000  WP_010922530.1  901 aa alpha-mannosidase n.s. ●○○○○ -0.8 -0.795201842218615
Mycobacterium avium subsp. paratuberculosis K10  MAP_2595  AAS04912.1  Q73WR5  585 aa hypothetical protein n.s. ●○○○○ -0.8 -0.795068591129293
Mycobacterium avium subsp. paratuberculosis K10  MAP_0907  AAS03224.1  Q742D0  282 aa hypothetical protein n.s. ●○○○○ -0.79 -0.794939974357798
Escherichia coli CFT073  c0914  AAN79387.1  Q8FJL0  gsiA  629 aa Hypothetical ABC transporter ATP-binding protein yliA n.s. ●○○○○ -0.79 -0.794832016824894
Mycobacterium avium subsp. paratuberculosis K10  MAP_2393c  AAS04710.1  Q73XB6  265 aa hypothetical protein n.s. ●○○○○ -0.79 -0.794811588281374
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4599  WP_001201297.1  E8XAS7  ytfH  128 aa transcriptional regulator n.s. ●○○○○ -0.79 -0.794700200627002
Haemophilus influenzae Rd KW20  HI_0534  NP_438692.1  P44324  aspA  475 aa aspartate ammonia-lyase n.s. ●○○○○ -0.79 -0.794655106395428
Streptococcus pyogenes M1 5448  SP5448_05875  WP_011285494.1  346 aa dTDP-glucose 4,6-dehydratase n.s. ●○○○○ -0.79 -0.794625040319776
Streptococcus pyogenes M1 5448  SP5448_08260  WP_010922654.1  357 aa glycerate kinase n.s. ●○○○○ -0.79 -0.794625040319776
Vibrio parahaemolyticus RIMD 2210633  VP_0159  BAC58422.1  Q87TB1  706 aa guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase n.s. ●○○○○ -0.79 -0.793953441287498
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4315  CBW20401.1  A0A0H3NKU9  yjfR  354 aa conserved hypothetical protein n.s. ●○○○○ -0.79 -0.793797375572351
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0837  WP_002868800.1  A0A0H3PHI3  fliP  244 aa flagellar type III secretion system pore protein FliP n.s. ●○○○○ -0.79 -0.79371922562
Vibrio parahaemolyticus RIMD 2210633  VPA_0748  BAC62091.1  Q87I58  32 aa hypothetical protein n.s. ●○○○○ -0.79 -0.793602504639249
Vibrio parahaemolyticus RIMD 2210633  VP_0138  BAC58401.1  Q87TD2  109 aa general secretion pathway protein I n.s. ●○○○○ -0.79 -0.793323230823033
Escherichia coli CFT073  c0619  AAN79096.1  Q8FK66  allS  308 aa Hypothetical transcriptional regulator ybbS n.s. ●○○○○ -0.79 -0.793097627960888
Escherichia coli CFT073  c0294  AAN78782.1  A0A0H2V4E2  721 aa Hypothetical protein n.s. ●○○○○ -0.79 -0.792787775546763
Escherichia coli CFT073  c3736  AAN82180.1  A0A0H2VAT6  308 aa Putative enzyme n.s. ●○○○○ -0.79 -0.792599206263096
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0875  CBW16971.1  A0A0H3N9J9  hcr  323 aa hybrid-cluster protein oxidoreductase-FAD and [2FE-2S] cofactors, NADH as electron donor n.s. ●○○○○ -0.79 -0.792449786267367
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1964  WP_000741710.1  E8XA78  ftnB  167 aa non-heme ferritin-like protein n.s. ●○○○○ -0.79 -0.792411528194539
Streptococcus pyogenes M1 5448  SP5448_07300  WP_010921995.1  322 aa serine kinase n.s. ●○○○○ -0.79 -0.792221699074614
Escherichia coli CFT073  c3012  AAN81462.1  A0A0H2VBV0  119 aa Protein yfgD n.s. ●○○○○ -0.79 -0.792188886294843
Serratia marcescens Strain UMH9  BVG96_05710  ASL97139.1  403 aa beta-ketoadipyl CoA thiolase n.s. ●○○○○ -0.79 -0.791780577864925
Escherichia coli CFT073  c2784  AAN81238.1  A0A0H2VBE9  glpC  421 aa Anaerobic glycerol-3-phosphate dehydrogenase subunit C n.s. ●○○○○ -0.79 -0.791772770553787
Mycobacterium avium subsp. paratuberculosis K10  MAP_1279c  AAS03596.1  Q740R3  730 aa hypothetical protein n.s. ●○○○○ -0.79 -0.79150852491672
Serratia marcescens Strain UMH9  BVG96_05135  ASL97029.1  241 aa leucyl/phenylalanyl-tRNA--protein transferase n.s. ●○○○○ -0.79 -0.791294075076895
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2608  WP_001526273.1  E8XGJ6  63 aa hypothetical protein n.s. ●○○○○ -0.79 -0.791190387667779
Haemophilus influenzae Rd KW20  HI_1234  NP_439390.1  P45120  mgsA  152 aa methylglyoxal synthase n.s. ●○○○○ -0.79 -0.791106222858778
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3928  CBW20019.1  A0A0H3NNI7  tatB  182 aa sec-independent protein translocase protein n.s. ●○○○○ -0.79 -0.790545294858452
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2036  CBW18132.1  A0A0H3ND06  yeeA  352 aa hypothetical membrane protein n.s. ●○○○○ -0.79 -0.790490101942103
Mycobacterium avium subsp. paratuberculosis K10  MAP_1867c  AAS04184.1  Q73YT8  pks5  2073 aa Pks5 n.s. ●○○○○ -0.79 -0.790401802014131
Escherichia coli O157:H7 str. EDL933  Z0296  AAG54560.1  88 aa hypothetical protein n.s. ●○○○○ -0.79 -0.790221645650255
Mycobacterium avium subsp. paratuberculosis K10  MAP_3850c  AAS06400.1  Q73T69  300 aa hypothetical protein n.s. ●○○○○ -0.79 -0.79002963244208
Streptococcus pyogenes M1 5448  SP5448_06115  WP_002984950.1  56 aa hypothetical protein n.s. ●○○○○ -0.79 -0.789818357829452
Mycobacterium avium subsp. paratuberculosis K10  MAP_3235c  AAS05783.1  Q73UY1  339 aa hypothetical protein n.s. ●○○○○ -0.79 -0.789719701515412
Escherichia coli M12  CO715_14665  ATI06844.1  185 aa protein DcrB n.s. ●○○○○ -0.79 -0.789426006688975
Escherichia coli M12  CO715_24535  ATI08598.1  152 aa xanthine phosphoribosyltransferase n.s. ●○○○○ -0.79 -0.789217360674726
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2547  CBW18647.2  A0A0H3NEH7  148 aa hypothetical transposase n.s. ●○○○○ -0.79 -0.789107382993641
Streptococcus pyogenes M1 5448  SP5448_02570  WP_002983521.1  325 aa tagatose-bisphosphate aldolase n.s. ●○○○○ -0.79 -0.788953154981194
Mycobacterium avium subsp. paratuberculosis K10  MAP_3198  AAS05746.1  Q73V18  128 aa hypothetical protein n.s. ●○○○○ -0.79 -0.788912383058618
Streptococcus pyogenes M1 5448  SP5448_04670  WP_010922377.1  123 aa GntR family transcriptional regulator n.s. ●○○○○ -0.79 -0.788857021331387
Vibrio parahaemolyticus RIMD 2210633  VP_1577  BAC59840.1  Q87PD7  252 aa hypothetical protein (Alteromonas phage PM2) n.s. ●○○○○ -0.79 -0.788156904837649
Streptococcus pyogenes M1 5448  SP5448_02305  WP_002988733.1  440 aa DEAD/DEAH box helicase n.s. ●○○○○ -0.79 -0.787607283883903
Escherichia coli CFT073  c3375  AAN81820.1  A0A0H2VA28  fucR  246 aa L-fucose operon activator n.s. ●○○○○ -0.79 -0.787163777839923
Mycobacterium avium subsp. paratuberculosis K10  MAP_1495  AAS03812.1  Q73ZV6  151 aa hypothetical protein n.s. ●○○○○ -0.79 -0.787018589463669
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0450  CBW16551.1  A0A0H3NA24  ybaE  566 aa hypothetical solute-binding protein n.s. ●○○○○ -0.79 -0.786901329906479
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4389  CBW20477.1  A0A0H3NPT4  yjgF  128 aa conserved hypothetical protein n.s. ●○○○○ -0.79 -0.786469226670521
Vibrio parahaemolyticus RIMD 2210633  VPA_1404  BAC62747.1  Q87GB3  437 aa hypothetical protein n.s. ●○○○○ -0.79 -0.786089319332321
Streptococcus pyogenes M1 5448  SP5448_08495  WP_002982624.1  204 aa peptide deformylase n.s. ●○○○○ -0.79 -0.785973011837193
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4331  CBW20417.1  A0A0H3NIV9  cycA  469 aa D-serine/D-alanine/glycine transporter n.s. ●○○○○ -0.79 -0.785952250782646
Mycobacterium avium subsp. paratuberculosis K10  MAP_3336c  AAS05886.1  Q73UN0  156 aa hypothetical protein n.s. ●○○○○ -0.79 -0.785939141861399
Haemophilus influenzae Rd KW20  HI_1345  NP_439496.1  P45169  potC  247 aa spermidine/putrescine ABC transporter membrane protein n.s. ●○○○○ -0.79 -0.785508324399384
Escherichia coli O157:H7 str. EDL933  Z3609  AAG57473.1  343 aa hypothetical protein n.s. ●○○○○ -0.79 -0.785453967228201
Escherichia coli CFT073  c1806  AAN80270.1  P0AAC1  uspE  316 aa Protein ydaA n.s. ●○○○○ -0.78 -0.784748497512895
Streptococcus pyogenes M1 5448  SP5448_08120  WP_011285395.1  463 aa TrkH family potassium uptake protein n.s. ●○○○○ -0.78 -0.784627140739902
Streptococcus pyogenes M1 5448  SP5448_04230  WP_002984194.1  663 aa excinuclease ABC subunit B n.s. ●○○○○ -0.78 -0.784434873440289
Escherichia coli CFT073  c1629  AAN80094.1  Q8FI28  ycgN  158 aa Hypothetical protein ycgN n.s. ●○○○○ -0.78 -0.784368123346132
Mycobacterium avium subsp. paratuberculosis K10  MAP_2419  AAS04736.1  Q73X90  pks14  116 aa Pks14 n.s. ●○○○○ -0.78 -0.784284626252802
Streptococcus pyogenes M1 5448  SP5448_05135  WP_010922320.1  468 aa pyruvate carboxylase subunit B n.s. ●○○○○ -0.78 -0.78385807154145
Vibrio parahaemolyticus RIMD 2210633  VPA_0603  BAC61946.1  Q87IK3  226 aa NodN-related protein n.s. ●○○○○ -0.78 -0.783522186359873
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0894  WP_002869100.1  A0A0H3PHE9  750 aa flagellar hook-associated protein FlgL n.s. ●○○○○ -0.78 -0.783384027124
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1499  WP_002822570.1  A0A0H3PB93  245 aa LysR family transcriptional regulator n.s. ●○○○○ -0.78 -0.783384027124
Streptococcus pyogenes M1 5448  SP5448_07895  WP_011106886.1  343 aa iron ABC transporter permease n.s. ●○○○○ -0.78 -0.783377403292418
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0783  WP_002857062.1  A0A0H3P9M4  aspC  389 aa pyridoxal phosphate-dependent aminotransferase n.s. ●○○○○ -0.78 -0.783108439364
Mycobacterium avium subsp. paratuberculosis K10  MAP_0827c  AAS03144.1  Q742K8  citA  390 aa CitA n.s. ●○○○○ -0.78 -0.783048427276064
Escherichia coli O157:H7 str. EDL933  Z0651  AAG54854.1  1398 aa hypothetical protein n.s. ●○○○○ -0.78 -0.783009497707898
Escherichia coli CFT073  c2315  AAN80774.1  P0A9A3  ftnB  167 aa Ferritin-like protein 2 n.s. ●○○○○ -0.78 -0.783002977071685
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2473  CBW18575.1  A0A0H3NKD0  xseA  449 aa Probable exodeoxyribonuclease VII large subunit n.s. ●○○○○ -0.78 -0.782984021934673
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0434  WP_002854302.1  A0A0H3PEZ1  frdB  241 aa fumarate reductase iron-sulfur subunit n.s. ●○○○○ -0.78 -0.782660713728
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1663  CBW17758.1  A0A0H3NHA5  ompW  212 aa hypothetical outer membrane protein n.s. ●○○○○ -0.78 -0.782503775180298
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4310  CBW20396.1  A0A0H3NKU6  aidB  540 aa probable acyl Co-A dehydrogenase n.s. ●○○○○ -0.78 -0.782499134180865
Vibrio parahaemolyticus RIMD 2210633  VPA_0187  BAC61530.1  Q87JR1  30 aa hypothetical protein n.s. ●○○○○ -0.78 -0.782418003326592
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0141  CBW16244.1  A0A0H3NCS2  guaC  347 aa GMP reductase n.s. ●○○○○ -0.78 -0.781954269301946
Streptococcus pyogenes M1 5448  SP5448_06150  WP_010922167.1  314 aa diphosphomevalonate decarboxylase n.s. ●○○○○ -0.78 -0.781550863946095
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4234  CBW20320.1  A0A0H3NKL0  melR  310 aa melibiose operon regulatory protein n.s. ●○○○○ -0.78 -0.781443447821468
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2750  CBW18849.1  A0A0H3NGP0  88 aa hypothetical transposase n.s. ●○○○○ -0.78 -0.781418842947083
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2725  CBW18825.1  A0A0H3NEX9  212 aa conserved hypothetical protein n.s. ●○○○○ -0.78 -0.781268363182484
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1208  CBW17303.1  A0A0H3NFT6  213 aa hypothetical membrane protein n.s. ●○○○○ -0.78 -0.781258566779614
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0065  WP_002866308.1  A0A0H3P996  194 aa thioredoxin n.s. ●○○○○ -0.78 -0.781225324794
Serratia marcescens Strain UMH9  BVG96_04745  ASL96952.1  206 aa glutathione S-transferase n.s. ●○○○○ -0.78 -0.781114649787615
Escherichia coli CFT073  c2672  AAN81128.1  Q8FFV5  dusC  338 aa Hypothetical protein yohI n.s. ●○○○○ -0.78 -0.781059042276569
Escherichia coli CFT073  c1637  AAN80102.1  A0A0H2V6X2  ycgB  510 aa Hypothetical protein ycgB n.s. ●○○○○ -0.78 -0.780910856408584
Mycobacterium avium subsp. paratuberculosis K10  MAP_0096c  AAS02413.1  Q744Z3  110 aa hypothetical protein n.s. ●○○○○ -0.78 -0.78082919150336
Mycobacterium avium subsp. paratuberculosis K10  MAP_0812  AAS03129.1  Q742M3  334 aa hypothetical protein n.s. ●○○○○ -0.78 -0.78076306310215
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2219  WP_010989040.1  E8XCX2  294 aa hypothetical protein n.s. ●○○○○ -0.78 -0.78040850367177
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1116  AIK79739.1  74 aa opgC family protein n.s. ●○○○○ -0.78 -0.780264336552924
Mycobacterium avium subsp. paratuberculosis K10  MAP_0917  AAS03234.1  Q742C0  mprB  511 aa hypothetical protein n.s. ●○○○○ -0.78 -0.780107087132046
Mycobacterium avium subsp. paratuberculosis K10  MAP_3793  AAS06343.1  Q73TC5  94 aa hypothetical protein n.s. ●○○○○ -0.78 -0.779928203664984
Mycobacterium avium subsp. paratuberculosis K10  MAP_2165  AAS04482.1  Q73XZ3  198 aa hypothetical protein n.s. ●○○○○ -0.78 -0.779909976866454
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0301  WP_000011535.1  E8XIV4  729 aa type VI secretion system tip protein VgrG n.s. ●○○○○ -0.78 -0.779863819386537
Mycobacterium avium subsp. paratuberculosis K10  MAP_2618c  AAS04935.1  Q73WP2  narJ  212 aa NarJ n.s. ●○○○○ -0.78 -0.779768264755426
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0954  WP_002853470.1  Q0Q7G3  303 aa AEC family transporter n.s. ●○○○○ -0.78 -0.779521865169
Streptococcus pyogenes M1 5448  SP5448_04930  WP_010922347.1  181 aa phosphopantothenoylcysteine decarboxylase n.s. ●○○○○ -0.78 -0.779339790000546
Retrieved entries 10,801–10,900 out of 36,363 total in 143.7 ms (Link to these results)