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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4805  AIK83332.1  270 aa tRNA pseudouridine(38-40) synthase n.s. ●○○○○ -0.29 -0.285606660476231
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1167  CBW17263.1  A0A0H3NC75  ycfD  373 aa conserved hypothetical protein n.s. ●○○○○ -0.29 -0.285580695743412
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3989  CBW20078.1  A0A0H3NI41  107 aa hypothetical exported protein n.s. ●○○○○ -0.29 -0.285514663006686
Acinetobacter baumannii ATCC 17978  A1S_2581  ABO12998.2  391 aa isochorismate synthetase n.s. ●○○○○ -0.29 -0.285249385720358
Streptococcus pyogenes M1 5448  SP5448_05210  WP_002984636.1  39 aa hypothetical protein n.s. ●○○○○ -0.29 -0.285116696345432
Streptococcus pyogenes M1 5448  SP5448_05210  WP_010922310.1  122 aa hypothetical protein n.s. ●○○○○ -0.29 -0.285116696345432
Serratia marcescens Strain UMH9  BVG96_08215  ASL97602.1  389 aa oxalate decarboxylase n.s. ●○○○○ -0.29 -0.285066363923326
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0114  WP_002851967.1  A0A0H3PCP5  cdtC  189 aa cytolethal distending toxin subunit Cj-CdtC n.s. ●○○○○ -0.28 -0.284985627198
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2051  CBW18147.1  A0A0H3NEM6  hisB  355 aa bifunctional histidine biosynthesis protein (imidazoleglycerol-phosphate dehydratase; histidinol phosphatase) n.s. ●○○○○ -0.28 -0.28498464551143
Vibrio parahaemolyticus RIMD 2210633  VPA_1516  BAC62859.1  Q87G04  253 aa putative two-component response regulator n.s. ●○○○○ -0.28 -0.284843508763268
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0779  WP_002872157.1  Q0Q7K3  329 aa DUF4917 family protein n.s. ●○○○○ -0.28 -0.284798618342
Mycobacterium avium subsp. paratuberculosis K10  MAP_3893c  AAS06443.1  Q73T26  pknG  763 aa PknG n.s. ●○○○○ -0.28 -0.284795846911286
Streptococcus pyogenes M1 5448  SP5448_01115  WP_002991199.1  223 aa rhomboid family intramembrane serine protease n.s. ●○○○○ -0.28 -0.284636028096399
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0578  WP_002854880.1  A0A0H3PJE8  317 aa DUF979 domain-containing protein n.s. ●○○○○ -0.28 -0.284581299755
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3375  WP_000202966.1  E8XBE9  ygiP  165 aa M48 family peptidase n.s. ●○○○○ -0.28 -0.284535390767386
Vibrio parahaemolyticus RIMD 2210633  VP_1116  BAC59379.1  Q87QN3  bioD  235 aa dethiobiotin synthetase n.s. ●○○○○ -0.28 -0.284496678850267
Serratia marcescens Strain UMH9  BVG96_07330  ASL97437.1  154 aa endopeptidase n.s. ●○○○○ -0.28 -0.284488922147487
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0628  WP_000052802.1  E8X979  ahpC  187 aa alkyl hydroperoxide reductase subunit C n.s. ●○○○○ -0.28 -0.284488123260666
Escherichia coli CFT073  c1110  AAN79578.1  P0AAC7  yccA  219 aa Hypothetical protein yccA n.s. ●○○○○ -0.28 -0.2844717974633
Escherichia coli CFT073  c1109  AAN79577.1  A0A0H2V7Y5  214 aa Hypothetical protein n.s. ●○○○○ -0.28 -0.2844717974633
Streptococcus pyogenes M1 5448  SP5448_04045  WP_010922413.1  556 aa DNA polymerase III subunit gamma/tau n.s. ●○○○○ -0.28 -0.284443760796786
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2140  CBW18236.1  A0A0H3NDH1  yehW  243 aa hypothetical permease transmembrane component n.s. ●○○○○ -0.28 -0.284377553046365
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0436  NP_232830.1  Q9KMC6  171 aa acetyltransferase n.s. ●○○○○ -0.28 -0.284305699645175
Streptococcus pyogenes M1 5448  SP5448_05725  WP_011285506.1  1368 aa type II CRISPR RNA-guided endonuclease Cas9 n.s. ●○○○○ -0.28 -0.284155359847367
Serratia marcescens Strain UMH9  BVG96_23430  ASM00386.1  119 aa L-fucose mutarotase n.s. ●○○○○ -0.28 -0.283975236140033
Haemophilus influenzae Rd KW20  HI_0097  NP_438271.2  P35755  fbpA  332 aa iron-utilization periplasmic protein hFbpA n.s. ●○○○○ -0.28 -0.283965940481139
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4407  WP_000729852.1  E8X8X5  475 aa phage tail sheath family protein n.s. ●○○○○ -0.28 -0.283962545083386
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3499  WP_001029671.1  E8XD42  nanA  297 aa N-acetylneuraminate lyase n.s. ●○○○○ -0.28 -0.28380391988211
Mycobacterium avium subsp. paratuberculosis K10  MAP_0560  AAS02877.1  Q743N1  fdxD  63 aa FdxD n.s. ●○○○○ -0.28 -0.283744681265752
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2799  CBW18897.1  A0A0H3NF30  emrA  390 aa multidrug resistance protein A n.s. ●○○○○ -0.28 -0.283716607458362
Serratia marcescens Strain UMH9  BVG96_09780  ASL97889.1  253 aa phosphatidylglycerophosphatase B n.s. ●○○○○ -0.28 -0.283540957404339
Acinetobacter baumannii ATCC 17978  A1S_2861  ABO13267.2  147 aa putative signal peptide n.s. ●○○○○ -0.28 -0.283447151943592
Acinetobacter baumannii ATCC 17978  A1S_2094  ABO12521.2  394 aa hypothetical protein n.s. ●○○○○ -0.28 -0.28343660190545
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3941  CBW20032.1  A0A0H3NJS6  mobB  171 aa molybdopterin-guanine dinucleotide biosynthesis protein B n.s. ●○○○○ -0.28 -0.28322657654438
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3349  CBW19444.1  A0A0H3NSL9  yhdH  324 aa possible oxidoreductase n.s. ●○○○○ -0.28 -0.283189795051049
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1753  WP_000210317.1  E8XKV3  yciA  133 aa acyl-CoA thioester hydrolase YciA n.s. ●○○○○ -0.28 -0.28316711228101
Vibrio parahaemolyticus RIMD 2210633  VPA_0829  BAC62172.1  Q87HX7  382 aa iron-containing alcohol dehydrogenase n.s. ●○○○○ -0.28 -0.283097859746968
Mycobacterium avium subsp. paratuberculosis K10  MAP_1384c  AAS03701.1  Q740G7  598 aa hypothetical protein n.s. ●○○○○ -0.28 -0.28308191736998
Escherichia coli CFT073  c1543  AAN80012.1  A0A0H2V8W4  193 aa Putative superinfection exclusion protein B of prophage n.s. ●○○○○ -0.28 -0.283015201487079
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2717  WP_000623091.1  E8XHJ0  643 aa phage terminase large subunit family protein n.s. ●○○○○ -0.28 -0.282928376552025
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3708  WP_000108342.1  E8XEP4  177 aa gluconokinase n.s. ●○○○○ -0.28 -0.282885855581868
Vibrio parahaemolyticus RIMD 2210633  VPA_0965  BAC62308.1  Q87HJ8  500 aa putative sensor histidine protein kinase UhpB n.s. ●○○○○ -0.28 -0.282875323784255
Escherichia coli CFT073  c3876  AAN82317.1  A0A0H2VBD8  tdcA  312 aa Tdc operon transcriptional activator n.s. ●○○○○ -0.28 -0.282780741287127
Mycobacterium avium subsp. paratuberculosis K10  MAP_1466c  AAS03783.1  Q73ZY5  376 aa hypothetical protein n.s. ●○○○○ -0.28 -0.282778031180948
Escherichia coli O157:H7 str. EDL933  Z2757  AAG56714.1  200 aa orf, hypothetical protein n.s. ●○○○○ -0.28 -0.282601506489682
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2115  CBW18211.1  A0A0H3NND4  111 aa hypothetical membrane protein n.s. ●○○○○ -0.28 -0.282497983035178
Streptococcus pyogenes M1 5448  SP5448_01605  WP_002982921.1  89 aa 30S ribosomal protein S14 n.s. ●○○○○ -0.28 -0.282328820501044
Streptococcus pyogenes M1 5448  SP5448_04210  WP_047343327.1  459 aa PTS sugar transporter subunit IIC n.s. ●○○○○ -0.28 -0.282232686851237
Mycobacterium avium subsp. paratuberculosis K10  MAP_3531c  AAS06081.1  Q73U37  fbpC2  352 aa FbpC2 n.s. ●○○○○ -0.28 -0.282221234808499
Escherichia coli CFT073  c3133  AAN81583.1  A0A0H2V9U9  420 aa Hypothetical protein n.s. ●○○○○ -0.28 -0.28214968936142
Serratia marcescens Strain UMH9  BVG96_06880  ASL97355.1  498 aa aldehyde dehydrogenase PuuC n.s. ●○○○○ -0.28 -0.281764504078672
Streptococcus pyogenes M1 5448  SP5448_01420  WP_002986000.1  307 aa ABC transporter ATP-binding protein n.s. ●○○○○ -0.28 -0.281752018602205
Streptococcus pyogenes M1 5448  SP5448_01420  WP_077707078.1  29 aa hypothetical protein n.s. ●○○○○ -0.28 -0.281752018602205
Streptococcus pyogenes M1 5448  SP5448_01315  WP_002986045.1  692 aa elongation factor G n.s. ●○○○○ -0.28 -0.281752018602205
Serratia marcescens Strain UMH9  BVG96_17205  ASL99249.1  325 aa tonB-system energizer ExbB n.s. ●○○○○ -0.28 -0.281739453265771
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1398  WP_002855407.1  A0A0H3PI76  497 aa oxidoreductase n.s. ●○○○○ -0.28 -0.281710634301
Serratia marcescens Strain UMH9  BVG96_04430  ASL96893.1  294 aa cytidine deaminase n.s. ●○○○○ -0.28 -0.281268609583853
Serratia marcescens Strain UMH9  BVG96_19590  ASL99692.1  1007 aa autotransporter outer membrane beta-barrel domain-containing protein n.s. ●○○○○ -0.28 -0.281112753626312
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4200  WP_000268253.1  E8XJK4  yihU  298 aa sulfolactaldehyde 3-reductase n.s. ●○○○○ -0.28 -0.280926886199686
Acinetobacter baumannii ATCC 17978  A1S_2626  ABO13043.2  904 aa DNA gyrase n.s. ●○○○○ -0.28 -0.280840818999238
Streptococcus pyogenes M1 5448  SP5448_03830  WP_002989155.1  514 aa peptide chain release factor 3 n.s. ●○○○○ -0.28 -0.28079068210414
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1364  WP_002856258.1  A1W0X9  ruvB  335 aa Holliday junction branch migration DNA helicase RuvB n.s. ●○○○○ -0.28 -0.280733764967
Serratia marcescens Strain UMH9  BVG96_01400  ASL96337.1  302 aa LysR family transcriptional regulator n.s. ●○○○○ -0.28 -0.280457821579782
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0448  WP_002857569.1  A0A0H3PBS8  127 aa hypothetical protein n.s. ●○○○○ -0.28 -0.280439448698
Serratia marcescens Strain UMH9  BVG96_00970  ASL96259.1  264 aa EEP domain-containing protein n.s. ●○○○○ -0.28 -0.280318790732772
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3380  CBW19475.1  A0A0H3NID2  yhdN  122 aa conserved hypothetical protein n.s. ●○○○○ -0.28 -0.28007959765512
Vibrio parahaemolyticus RIMD 2210633  VP_1542  BAC59805.1  Q87PG0  57 aa cytochrome c oxidase, subunit CcoQ n.s. ●○○○○ -0.28 -0.279889294512339
Serratia marcescens Strain UMH9  BVG96_13465  ASL98573.1  505 aa amidophosphoribosyltransferase n.s. ●○○○○ -0.28 -0.279847735132586
Serratia marcescens Strain UMH9  BVG96_04595  ASL96923.1  443 aa HlyD family type I secretion periplasmic adaptor subunit n.s. ●○○○○ -0.28 -0.279827716895768
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0551  WP_000495330.1  E8X8B7  ylbE  419 aa DUF1116 domain-containing protein n.s. ●○○○○ -0.28 -0.279412361936387
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3662  CBW19755.1  A0A0H3NTN5  398 aa hypothetical racemase n.s. ●○○○○ -0.28 -0.279236960750726
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3666  WP_000446437.1  E8XEK2  yhgE  569 aa DUF4153 domain-containing protein n.s. ●○○○○ -0.28 -0.279222441271995
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0298  WP_002857542.1  A0A0H3PBY8  151 aa thioredoxin-dependent thiol peroxidase n.s. ●○○○○ -0.28 -0.279208138601
Vibrio parahaemolyticus RIMD 2210633  VP_1448  BAC59711.1  Q87PQ3  209 aa anaerobic dimethyl sulfoxide reductase, subunit B n.s. ●○○○○ -0.28 -0.279068295617557
Haemophilus influenzae Rd KW20  HI_1037  NP_439197.1  P44098  294 aa hypothetical protein n.s. ●○○○○ -0.28 -0.278863015629507
Haemophilus influenzae Rd KW20  HI_0471  NP_438632.1  P44327  hisB  362 aa imidazole glycerol-phosphate dehydratase/histidinol phosphatase n.s. ●○○○○ -0.28 -0.278863015629507
Mycobacterium avium subsp. paratuberculosis K10  MAP_2061  AAS04378.1  Q73Y95  130 aa hypothetical protein n.s. ●○○○○ -0.28 -0.278702337298924
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3878  CBW19968.1  A0A0H3NND7  wzzE  348 aa lipopolysaccharide biosynthesis protein n.s. ●○○○○ -0.28 -0.278424518065994
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2563  WP_000512359.1  E8XFR9  eutH  408 aa ethanolamine utilization protein EutH n.s. ●○○○○ -0.28 -0.278402042933653
Escherichia coli CFT073  c2970  AAN81420.1  Q8FFA3  hemF  300 aa Coproporphyrinogen III oxidase, aerobic n.s. ●○○○○ -0.28 -0.278210128419294
Vibrio parahaemolyticus RIMD 2210633  VP_1134  BAC59397.1  Q87QL5  533 aa conserved hypothetical protein n.s. ●○○○○ -0.28 -0.278136540846177
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0538  WP_002859054.1  A0A0H3PBM7  96 aa metal-sensing transcriptional repressor n.s. ●○○○○ -0.28 -0.278136332923
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1047  NP_233429.1  Q9KKQ5  193 aa mannitol repressor protein n.s. ●○○○○ -0.28 -0.277901601785364
Vibrio parahaemolyticus RIMD 2210633  VPA_0578  BAC61922.1  Q87IM7  31 aa hypothetical protein n.s. ●○○○○ -0.28 -0.277733136396928
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3039  AIK81624.1  69 aa putative stress response protein n.s. ●○○○○ -0.28 -0.27769100178199
Haemophilus influenzae Rd KW20  HI_0737  NP_438896.1  O05031  265 aa acetohydroxy acid synthase II n.s. ●○○○○ -0.28 -0.27765919843417
Mycobacterium avium subsp. paratuberculosis K10  MAP_3550  AAS06100.1  Q73U18  ephF  296 aa EphF n.s. ●○○○○ -0.28 -0.277642185341877
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1587  WP_002868827.1  A0A0H3PAK3  hisH-2  195 aa imidazole glycerol phosphate synthase subunit HisH n.s. ●○○○○ -0.28 -0.27748526232
Escherichia coli CFT073  c0696  AAN79171.1  Q8FK07  uspG  153 aa Unknown protein from 2D-page n.s. ●○○○○ -0.28 -0.277398525401451
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0926  CBW17022.1  A0A0H3N9T1  297 aa conserved hypothetical protein n.s. ●○○○○ -0.28 -0.277160525487636
Mycobacterium avium subsp. paratuberculosis K10  MAP_1885c  AAS04202.1  Q73YS0  176 aa hypothetical protein n.s. ●○○○○ -0.28 -0.277155142903715
Streptococcus pyogenes M1 5448  SP5448_08895  WP_010922728.1  272 aa RluA family pseudouridine synthase n.s. ●○○○○ -0.28 -0.277137603411494
Escherichia coli CFT073  c3072  AAN81522.1  A0A0H2VB31  yphH  399 aa Hypothetical protein yphH n.s. ●○○○○ -0.28 -0.277042662306646
Mycobacterium avium subsp. paratuberculosis K10  MAP_0556c  AAS02873.1  Q743N5  fadD17  503 aa FadD17 n.s. ●○○○○ -0.28 -0.277034841381316
Vibrio parahaemolyticus RIMD 2210633  VP_0960  BAC59223.1  Q87R38  252 aa uridine phosphorylase n.s. ●○○○○ -0.28 -0.276686659058041
Vibrio parahaemolyticus RIMD 2210633  VPA_1424  BAC62767.1  Q87G93  635 aa PTS system, fructose-specific IIABC component n.s. ●○○○○ -0.28 -0.276641834313714
Serratia marcescens Strain UMH9  BVG96_13010  ASL98495.1  335 aa nucleoid-associated protein YejK n.s. ●○○○○ -0.28 -0.276592423538231
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3190  CBW19288.1  A0A0H3NS38  aer  506 aa aerotaxis receptor protein n.s. ●○○○○ -0.28 -0.276489286178417
Streptococcus pyogenes M1 5448  SP5448_08515  WP_010922681.1  618 aa proline--tRNA ligase n.s. ●○○○○ -0.28 -0.276464667862848
Escherichia coli CFT073  c2109  AAN80569.1  P0A6X8  ihfA  99 aa Integration host factor alpha-subunit n.s. ●○○○○ -0.28 -0.27641188116885
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