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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Streptococcus pyogenes M1 5448  SP5448_03650  WP_011285619.1  471 aa terminase n.s. ●○○○○ -0.23 -0.229551446757286
Escherichia coli CFT073  c4166  AAN82604.1  A0A0H2VBJ1  mrcA  858 aa Penicillin-binding protein 1A n.s. ●○○○○ -0.23 -0.229374861542169
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0284  CBW16385.1  A0A0H3N8F5  vgrS  729 aa Type VI secretion protein n.s. ●○○○○ -0.23 -0.229348703885439
Escherichia coli CFT073  c4731  AAN83164.1  A0A0H2VFA6  yigA  235 aa Hypothetical protein yigA n.s. ●○○○○ -0.23 -0.229316688442418
Haemophilus influenzae Rd KW20  HI_1198  NP_439354.1  P45103  207 aa hypothetical protein n.s. ●○○○○ -0.23 -0.229282551023448
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2864  AIK81453.1  206 aa FKBP-type peptidyl-prolyl cis-trans isomerase n.s. ●○○○○ -0.23 -0.229252335251291
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2768  CBW18866.1  A0A0H3NKZ3  tctE  471 aa hypothetical two-component system sensor kinase n.s. ●○○○○ -0.23 -0.229194557427522
Serratia marcescens Strain UMH9  BVG96_00230  ASL96131.1  788 aa DNA polymerase II n.s. ●○○○○ -0.23 -0.229122248267565
Serratia marcescens Strain UMH9  BVG96_08195  ASL97598.1  400 aa MFS transporter n.s. ●○○○○ -0.23 -0.228836520455187
Serratia marcescens Strain UMH9  BVG96_07295  ASL97431.1  384 aa UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase n.s. ●○○○○ -0.23 -0.228734046978413
Acinetobacter baumannii ATCC 17978  A1S_2316  ABO12738.2  333 aa membrane-bound lytic murein transglycosylase B n.s. ●○○○○ -0.23 -0.228718251198705
Serratia marcescens Strain UMH9  BVG96_18775  ASL99541.1  282 aa taurine dioxygenase n.s. ●○○○○ -0.23 -0.228467329808618
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0484  WP_000684912.1  E8X850  428 aa ammonium transporter AmtB n.s. ●○○○○ -0.23 -0.228439905596361
Serratia marcescens Strain UMH9  BVG96_11435  ASL98197.1  176 aa type VI secretion system-associated lipoprotein n.s. ●○○○○ -0.23 -0.228324393253475
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4657  WP_000148570.1  E8XBL2  pyrI  153 aa aspartate carbamoyltransferase regulatory subunit n.s. ●○○○○ -0.23 -0.228152855422177
Acinetobacter baumannii ATCC 17978  A1S_1748  ABO12175.2  197 aa replication protein n.s. ●○○○○ -0.23 -0.228078837255125
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3495  CBW19589.2  A0A0H3NIQ5  486 aa hypothetical membrane protein n.s. ●○○○○ -0.23 -0.228053045126249
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1825  WP_001240769.1  E8X8H4  510 aa SpoVR family protein n.s. ●○○○○ -0.23 -0.227827181734827
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0866  CBW16962.1  A0A0H3NEU6  artI  243 aa arginine-binding periplasmic protein 1 precursor n.s. ●○○○○ -0.23 -0.227666887369452
Vibrio parahaemolyticus RIMD 2210633  VPA_0993  BAC62336.1  Q87HH2  898 aa hypothetical protein n.s. ●○○○○ -0.23 -0.227568382990419
Escherichia coli CFT073  c4842  AAN83271.1  P0AEL1  fdoI  211 aa Formate dehydrogenase n.s. ●○○○○ -0.23 -0.22755149142889
Vibrio parahaemolyticus RIMD 2210633  VP_0886  BAC59149.1  Q87RB1  780 aa hypothetical membrane protein n.s. ●○○○○ -0.23 -0.227398200975526
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3978  CBW20068.1  A0A0H3NI33  309 aa hypothetical lipase n.s. ●○○○○ -0.23 -0.227360367364115
Vibrio parahaemolyticus RIMD 2210633  VPA_1626  BAC62969.1  Q87FQ2  204 aa Sco1-related protein n.s. ●○○○○ -0.23 -0.227266987503695
Escherichia coli CFT073  c3922  AAN82363.1  P60341  truB  314 aa tRNA pseudouridine synthase B n.s. ●○○○○ -0.23 -0.227255866001196
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3493  WP_000076266.1  E8XD36  codB  417 aa cytosine permease n.s. ●○○○○ -0.23 -0.227088677250951
Escherichia coli CFT073  c4344  AAN82780.1  A0A0H2VEI6  yhjN  808 aa Cyclic di-GMP binding protein precursor n.s. ●○○○○ -0.23 -0.226554793068975
Haemophilus influenzae Rd KW20  HI_0030  NP_438203.1  Q57092  rlpA  287 aa lipoprotein n.s. ●○○○○ -0.23 -0.226537492405347
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4306  CBW20392.1  A0A0H3NIS4  yjfK  227 aa conserved hypothetical protein n.s. ●○○○○ -0.23 -0.226332987747508
Acinetobacter baumannii ATCC 17978  A1S_2914  ABO13319.2  633 aa preprotein translocase IISP family, part of the channel n.s. ●○○○○ -0.23 -0.22615516776744
Vibrio parahaemolyticus RIMD 2210633  VP_1494  BAC59757.1  Q87PK8  nagK  302 aa ROK family protein n.s. ●○○○○ -0.23 -0.226058566249714
Serratia marcescens Strain UMH9  BVG96_23650  ASM00427.1  172 aa non-canonical purine NTP phosphatase n.s. ●○○○○ -0.23 -0.226042421566086
Serratia marcescens Strain UMH9  BVG96_03835  ASL96783.1  484 aa MFS transporter n.s. ●○○○○ -0.23 -0.226005990653702
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3732  CBW19824.1  A0A0H3NHH7  247 aa conserved hypothetical protein n.s. ●○○○○ -0.23 -0.225962531488062
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3322  CBW19418.1  A0A0H3NGI5  243 aa conserved hypothetical protein n.s. ●○○○○ -0.23 -0.225910771426235
Streptococcus pyogenes M1 5448  SP5448_01720  WP_002983074.1  197 aa signal peptidase I n.s. ●○○○○ -0.23 -0.225706100765027
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4359  CBW20446.1  A0A0H3NJ69  iolI1  277 aa endonuclease n.s. ●○○○○ -0.23 -0.225546559669776
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1388  CBW17484.1  A0A0H3NGE6  rnfD  352 aa Electron transport complex protein rnfD n.s. ●○○○○ -0.23 -0.225178405205779
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2478  CBW18579.1  A0A0H3NFZ1  sinI  319 aa hypothetical exported protein n.s. ●○○○○ -0.23 -0.225117478247066
Serratia marcescens Strain UMH9  BVG96_09425  ASL97828.1  345 aa hypothetical protein n.s. ●○○○○ -0.23 -0.225007737708193
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0268  NP_232666.1  Q9KMQ2  643 aa methyl-accepting chemotaxis protein n.s. ●○○○○ -0.22 -0.224956651945017
Mycobacterium avium subsp. paratuberculosis K10  MAP_1340c  AAS03657.1  Q740L0  259 aa hypothetical protein n.s. ●○○○○ -0.22 -0.224955539158467
Streptococcus pyogenes M1 5448  SP5448_06505  WP_011285478.1  824 aa phosphoglycerol transferase n.s. ●○○○○ -0.22 -0.224840897916769
Escherichia coli CFT073  c3906  AAN82347.1  A0A0H2VB29  yraR  211 aa Hypothetical protein yraR n.s. ●○○○○ -0.22 -0.224840143078612
Vibrio parahaemolyticus RIMD 2210633  VP_1961  BAC60224.1  P22095  trpA  268 aa tryptophan synthase, alpha subunit n.s. ●○○○○ -0.22 -0.224829579320648
Vibrio parahaemolyticus RIMD 2210633  VPA_0464  BAC61807.1  Q87IZ2  652 aa putative TrkA family protein n.s. ●○○○○ -0.22 -0.224784900793373
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3417  WP_000490601.1  E8XC77  457 aa PTS galactitol transporter subunit IIC n.s. ●○○○○ -0.22 -0.224780663980282
Vibrio parahaemolyticus RIMD 2210633  VPA_0521  BAC61865.1  Q87IT4  115 aa hypothetical protein n.s. ●○○○○ -0.22 -0.224745855059777
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0687  WP_074468912.1  A0A0H3PAS1  368 aa hypothetical protein n.s. ●○○○○ -0.22 -0.224685805911
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0175  WP_000829968.1  E8XHW4  speE  286 aa polyamine aminopropyltransferase n.s. ●○○○○ -0.22 -0.224500274017412
Escherichia coli O157:H7 str. EDL933  Z5665  AAG59264.1  430 aa orf, hypothetical protein n.s. ●○○○○ -0.22 -0.224408619928244
Haemophilus influenzae Rd KW20  HI_0468  NP_438629.1  P43853  hisG  303 aa ATP phosphoribosyltransferase n.s. ●○○○○ -0.22 -0.224365940378813
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4306  AIK82851.1  118 aa BMC domain protein n.s. ●○○○○ -0.22 -0.224317629544342
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1326  WP_002854125.1  A0A0H3P9P2  74 aa hypothetical protein n.s. ●○○○○ -0.22 -0.224298202622
Streptococcus pyogenes M1 5448  SP5448_06565  WP_000048058.1  58 aa 30S ribosomal protein S21 n.s. ●○○○○ -0.22 -0.22426409601793
Acinetobacter baumannii ATCC 17978  A1S_2926  ABO13331.1  62 aa hypothetical protein n.s. ●○○○○ -0.22 -0.224259793789559
Streptococcus pyogenes M1 5448  SP5448_04055  WP_002984078.1  313 aa bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor n.s. ●○○○○ -0.22 -0.224167962368123
Vibrio parahaemolyticus RIMD 2210633  VP_1270  BAC59533.1  Q87Q80  1012 aa conserved hypothetical protein n.s. ●○○○○ -0.22 -0.223905516937433
Mycobacterium avium subsp. paratuberculosis K10  MAP_4009  AAS06559.1  Q73SR4  245 aa hypothetical protein n.s. ●○○○○ -0.22 -0.223809307390749
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4328  CBW20414.1  A0A0H3NJ44  yifZ  308 aa hypothetical membrane protein n.s. ●○○○○ -0.22 -0.223781904236993
Serratia marcescens Strain UMH9  BVG96_02930  ASL96612.1  241 aa nicotinamide riboside transporter PnuC n.s. ●○○○○ -0.22 -0.223739463437886
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4134  CBW20222.1  A0A0H3NP38  201 aa predicted bacteriophage protein n.s. ●○○○○ -0.22 -0.223663333638802
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3192  WP_001055885.1  E8X9L6  fldB  173 aa flavodoxin FldB n.s. ●○○○○ -0.22 -0.223533687026767
Escherichia coli CFT073  c3833  AAN82278.1  A0A0H2VAZ6  ebgA  1089 aa Evolved beta-galactosidase alpha-subunit n.s. ●○○○○ -0.22 -0.223237939127157
Serratia marcescens Strain UMH9  BVG96_13710  ASL98620.1  183 aa thiol:disulfide interchange protein n.s. ●○○○○ -0.22 -0.223236274653171
Serratia marcescens Strain UMH9  BVG96_00830  ASL96237.1  171 aa S-ribosylhomocysteine lyase n.s. ●○○○○ -0.22 -0.223198521041895
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0785  WP_001109234.1  E8XAZ0  aroG  350 aa 3-deoxy-7-phosphoheptulonate synthase AroG n.s. ●○○○○ -0.22 -0.223141110023729
Mycobacterium avium subsp. paratuberculosis K10  MAP_1389  AAS03706.1  Q740G2  968 aa hypothetical protein n.s. ●○○○○ -0.22 -0.222974736359589
Vibrio parahaemolyticus RIMD 2210633  VP_1861  BAC60124.1  Q87NK7  175 aa hypothetical protein n.s. ●○○○○ -0.22 -0.222870313417157
Streptococcus pyogenes M1 5448  SP5448_08905  WP_010922730.1  498 aa C69 family dipeptidase n.s. ●○○○○ -0.22 -0.222822091270833
Vibrio parahaemolyticus RIMD 2210633  VPA_1205  BAC62548.1  Q87GW0  246 aa acetoacetyl-CoA reductase n.s. ●○○○○ -0.22 -0.222807798830311
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0438  WP_002857555.1  A0A0H3PEX7  242 aa gluconate 2-dehydrogenase subunit 3 family protein n.s. ●○○○○ -0.22 -0.222791237552
Streptococcus pyogenes M1 5448  SP5448_08825  WP_009880864.1  169 aa phosphatidylglycerophosphatase A n.s. ●○○○○ -0.22 -0.22262982397122
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0481  WP_002868795.1  A0A0H3PES6  319 aa hypothetical protein n.s. ●○○○○ -0.22 -0.222620064101
Vibrio parahaemolyticus RIMD 2210633  VPA_1256  BAC62599.1  Q87GQ9  534 aa hypothetical protein n.s. ●○○○○ -0.22 -0.222466972804602
Serratia marcescens Strain UMH9  BVG96_13945  ASL98663.1  131 aa N-acetyltransferase n.s. ●○○○○ -0.22 -0.222161015946785
Mycobacterium avium subsp. paratuberculosis K10  MAP_3951c  AAS06501.1  Q73SX2  679 aa hypothetical protein n.s. ●○○○○ -0.22 -0.222158168135988
Serratia marcescens Strain UMH9  BVG96_22420  ASM00195.1  312 aa malate dehydrogenase n.s. ●○○○○ -0.22 -0.221980470170748
Streptococcus pyogenes M1 5448  SP5448_07700  WP_010921955.1  184 aa NUDIX hydrolase n.s. ●○○○○ -0.22 -0.221956888422574
Serratia marcescens Strain UMH9  BVG96_13490  ASL98578.1  220 aa hypothetical protein n.s. ●○○○○ -0.22 -0.22173034087961
Serratia marcescens Strain UMH9  BVG96_20930  ASM00626.1  241 aa NAD-dependent aldehyde dehydrogenase n.s. ●○○○○ -0.22 -0.221728215478493
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2892  CBW18991.1  A0A0H3NFB8  498 aa possible permease n.s. ●○○○○ -0.22 -0.221700943872606
Vibrio parahaemolyticus RIMD 2210633  VP_2756  BAC61019.1  P59620  argH  624 aa argininosuccinase and n-acetylglutamate synthase n.s. ●○○○○ -0.22 -0.221527821324927
Mycobacterium avium subsp. paratuberculosis K10  MAP_0789  AAS03106.1  Q742P6  fadA  403 aa FadA_1 n.s. ●○○○○ -0.22 -0.221440967762571
Escherichia coli CFT073  c0729  AAN79202.1  A0A0H2V556  phpB  204 aa Alpha-ribazole-5'-phosphate phosphatase n.s. ●○○○○ -0.22 -0.22128291177767
Serratia marcescens Strain UMH9  BVG96_12445  ASL98384.1  276 aa N-acetylmuramoyl-L-alanine amidase n.s. ●○○○○ -0.22 -0.22116844429612
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1651  WP_002868872.1  A0A0H3PBF8  467 aa DUF2318 domain-containing protein n.s. ●○○○○ -0.22 -0.221156101249
Escherichia coli O157:H7 str. EDL933  Z3635  AAG57498.1  314 aa putative receptor protein n.s. ●○○○○ -0.22 -0.22114560317523
Escherichia coli CFT073  c3510  AAN81958.1  A0A0H2VCT3  236 aa Putative ATP-binding protein of ABC transport system n.s. ●○○○○ -0.22 -0.221144461831665
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1021  WP_002853517.1  A0A0H3PCX8  172 aa rhomboid family intramembrane serine protease n.s. ●○○○○ -0.22 -0.221139429577
Vibrio parahaemolyticus RIMD 2210633  VP_2080  BAC60343.1  Q87MZ6  321 aa ABC transporter substrate-binding protein n.s. ●○○○○ -0.22 -0.221068043894274
Mycobacterium avium subsp. paratuberculosis K10  MAP_0671  AAS02988.1  Q743B4  324 aa hypothetical protein n.s. ●○○○○ -0.22 -0.220462067879382
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0400  WP_000705165.1  E8XJT4  106 aa phosphate starvation-inducible protein PsiF n.s. ●○○○○ -0.22 -0.220433277906218
Acinetobacter baumannii ATCC 17978  A1S_2951  ABO13356.2  111 aa putative sulfide dehydrogenase n.s. ●○○○○ -0.22 -0.22019368428342
Escherichia coli CFT073  c3687  AAN82135.1  P62587  kpsE  382 aa KpsE protein n.s. ●○○○○ -0.22 -0.220154450794785
Mycobacterium avium subsp. paratuberculosis K10  MAP_2389c  AAS04706.1  Q73XC0  400 aa hypothetical protein n.s. ●○○○○ -0.22 -0.220113397817242
Vibrio parahaemolyticus RIMD 2210633  VP_0775  BAC59038.1  Q79YZ1  131 aa polar flagellar FlgB n.s. ●○○○○ -0.22 -0.220097190329239
Vibrio parahaemolyticus RIMD 2210633  VP_1309  BAC59572.1  Q87Q41  54 aa hypothetical protein n.s. ●○○○○ -0.22 -0.219921331721047
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0272  CBW16373.1  A0A0H3N7X2  161 aa conserved hypothetical protein (SPI-6 associated) n.s. ●○○○○ -0.22 -0.219801298680861
Acinetobacter baumannii ATCC 17978  A1S_2809  ABO13215.2  46 aa bacteriolytic lipoprotein entericidin B n.s. ●○○○○ -0.22 -0.21974655826704
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