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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Vibrio parahaemolyticus RIMD 2210633  VPA_1159  BAC62502.1  Q87H06  guaC  348 aa GMP reductase n.s. ●○○○○ -0.1 -0.100677575175649
Vibrio parahaemolyticus RIMD 2210633  VP_2625  BAC60888.1  Q87LI7  trmB  239 aa conserved hypothetical protein n.s. ●○○○○ -0.1 -0.10062657940139
Haemophilus influenzae Rd KW20  HI_0475  NP_438636.1  P44434  hisI  221 aa bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase n.s. ●○○○○ -0.1 -0.100519584638396
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1591  WP_002868829.1  A0A0H3PAJ4  hisI  207 aa bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE n.s. ●○○○○ -0.1 -0.100468908896
Acinetobacter baumannii ATCC 17978  A1S_0013  ABO10510.2  375 aa hypothetical protein n.s. ●○○○○ -0.1 -0.100328444864263
Vibrio parahaemolyticus RIMD 2210633  VPA_0930  BAC62273.1  Q87HN3  229 aa molybdenum ABC transporter, permease protein n.s. ●○○○○ -0.1 -0.100208391819664
Serratia marcescens Strain UMH9  BVG96_22260  ASM00166.1  243 aa 23S rRNA (guanosine(2251)-2'-O)-methyltransferase n.s. ●○○○○ -0.1 -0.100207651354787
Serratia marcescens Strain UMH9  BVG96_22465  ASM00204.1  220 aa DNA-binding response regulator n.s. ●○○○○ -0.1 -0.100156215013692
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2909  WP_001111809.1  E8XJD4  iroC  1217 aa ABC transporter ATP-binding protein n.s. ●○○○○ -0.1 -0.100134501786658
Haemophilus influenzae Rd KW20  HI_1266  NP_439421.1  P44145  128 aa hypothetical protein n.s. ●○○○○ -0.1 -0.0999549711356334
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0777  NP_230426.1  H9L4Q8  350 aa ferric vibriobactin ABC transporter permease n.s. ●○○○○ -0.1 -0.0999318352540242
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0483  CBW16583.1  A0A0H3NDR8  aes  323 aa acetyl esterase n.s. ●○○○○ -0.1 -0.0998979456213198
Streptococcus pyogenes M1 5448  SP5448_00250  WP_015055884.1  163 aa 5-(carboxyamino)imidazole ribonucleotide mutase n.s. ●○○○○ -0.1 -0.0996748858687316
Vibrio parahaemolyticus RIMD 2210633  VPA_0350  BAC61693.1  Q87JA3  339 aa putative ATP-binding component of ABC transporter n.s. ●○○○○ -0.1 -0.0996523490680522
Serratia marcescens Strain UMH9  BVG96_15370  ASL98927.1  323 aa patatin n.s. ●○○○○ -0.1 -0.0996402582696072
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2156  CBW18252.1  A0A0H3NNI2  452 aa hypothetical n-hydroxybenzoate transporter n.s. ●○○○○ -0.1 -0.0995345795114153
Mycobacterium avium subsp. paratuberculosis K10  MAP_0151c  AAS02468.1  Q745E8  150 aa hypothetical protein n.s. ●○○○○ -0.1 -0.0995328670317616
Streptococcus pyogenes M1 5448  SP5448_06960  WP_011285454.1  273 aa PTS mannose/fructose/sorbose transporter family subunit IID n.s. ●○○○○ -0.1 -0.0994826185691187
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4482  AIK83025.1  287 aa ABC 3 transport family protein n.s. ●○○○○ -0.1 -0.099455484367444
Escherichia coli CFT073  c2582  AAN81037.1  A0A0H2V8R8  wcaD  429 aa Putative colanic acid polymerase n.s. ●○○○○ -0.1 -0.0994531329827888
Mycobacterium avium subsp. paratuberculosis K10  MAP_2775  AAS05092.1  Q73W85  295 aa hypothetical protein n.s. ●○○○○ -0.1 -0.0994279929232275
Haemophilus influenzae Rd KW20  HI_0195.1  NP_438364.1  Q57362  1111 aa potassium efflux protein KefA n.s. ●○○○○ -0.1 -0.0993699154343076
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4512  WP_001110452.1  E8X9W7  97 aa DUF1778 domain-containing protein n.s. ●○○○○ -0.1 -0.0993096150111706
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1511  AIK80132.1  180 aa hypothetical protein n.s. ●○○○○ -0.1 -0.0992607501774728
Escherichia coli O157:H7 str. EDL933  Z3191  AAG57088.1  468 aa gluconate-6-phosphate dehydrogenase, decarboxylating n.s. ●○○○○ -0.1 -0.099199709527697
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1291  WP_000029246.1  E8XFL6  398 aa anaerobic sulfatase maturase n.s. ●○○○○ -0.1 -0.0989948874395403
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2439  AIK81036.1  115 aa bacterial chaperone lipo family protein n.s. ●○○○○ -0.1 -0.09898030477895
Vibrio parahaemolyticus RIMD 2210633  VPA_0680  BAC62023.1  Q87IC6  515 aa arylsulfatase n.s. ●○○○○ -0.1 -0.0989317919628806
Vibrio parahaemolyticus RIMD 2210633  VPA_0853  BAC62196.1  Q87HV3  160 aa putative membrane protein YcdZ n.s. ●○○○○ -0.1 -0.0988889631353844
Vibrio parahaemolyticus RIMD 2210633  VPA_1663  BAC63006.1  Q87FL6  414 aa putative binding protein component of ABC sugar transporter n.s. ●○○○○ -0.1 -0.0988578404215019
Serratia marcescens Strain UMH9  BVG96_02380  ASL96520.1  175 aa N-acetyltransferase n.s. ●○○○○ -0.1 -0.0988524096131125
Vibrio parahaemolyticus RIMD 2210633  VP_2361  BAC60624.1  Q87M96  39 aa hypothetical protein n.s. ●○○○○ -0.1 -0.0988267064728375
Mycobacterium avium subsp. paratuberculosis K10  MAP_0899c  AAS03216.1  Q742D6  282 aa hypothetical protein n.s. ●○○○○ -0.1 -0.0988135874478839
Vibrio parahaemolyticus RIMD 2210633  VP_1431  BAC59694.1  Q87PS0  592 aa putative ATP-binding component of a transport system n.s. ●○○○○ -0.1 -0.0986766710127541
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0688  WP_001278615.1  E8XA26  corc  292 aa magnesium/cobalt transporter CorC n.s. ●○○○○ -0.1 -0.0986666675521071
Escherichia coli CFT073  c3623  AAN82071.1  A0A0H2VAM3  iutA  759 aa IutA protein n.s. ●○○○○ -0.1 -0.0986212137468526
Serratia marcescens Strain UMH9  BVG96_05935  ASL97179.1  181 aa N-acetyltransferase n.s. ●○○○○ -0.1 -0.0986178398065371
Acinetobacter baumannii ATCC 17978  A1S_2560  ABO12977.2  421 aa hypothetical protein n.s. ●○○○○ -0.1 -0.0983297172953297
Escherichia coli O157:H7 str. EDL933  Z3713  AAG57566.1  111 aa detox protein n.s. ●○○○○ -0.1 -0.0982043712027837
Serratia marcescens Strain UMH9  BVG96_06595  ASL97302.1  161 aa hypothetical protein n.s. ●○○○○ -0.1 -0.0981900265867107
Serratia marcescens Strain UMH9  BVG96_16830  ASL99184.1  256 aa ABC transporter permease n.s. ●○○○○ -0.1 -0.0981852601449024
Vibrio parahaemolyticus RIMD 2210633  VP_0607  BAC58870.1  Q87S17  316 aa hypothetical protein n.s. ●○○○○ -0.1 -0.0980988462107286
Escherichia coli O157:H7 str. EDL933  Z5527  AAG59170.1  614 aa outer membrane receptor for transport of vitamin B12, E colicins, and bacteriophage BF23 n.s. ●○○○○ -0.1 -0.0977045068412319
Haemophilus influenzae Rd KW20  HI_0613  NP_438771.1  P44399  fucK  470 aa L-fuculokinase n.s. ●○○○○ -0.1 -0.0977009555261781
Serratia marcescens Strain UMH9  BVG96_22865  ASM00276.1  238 aa LuxR family transcriptional regulator n.s. ●○○○○ -0.1 -0.0976969949087569
Vibrio parahaemolyticus RIMD 2210633  VPA_0689  BAC62032.1  Q87IB7  576 aa hypothetical protein n.s. ●○○○○ -0.1 -0.0975934305091603
Streptococcus pyogenes M1 5448  SP5448_04720  WP_011285556.1  257 aa hypothetical protein n.s. ●○○○○ -0.1 -0.0974638119231826
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2414  CBW18516.1  A0A0H3NPD2  hemF  299 aa Coproporphyrinogen III oxidase, aerobic n.s. ●○○○○ -0.1 -0.0974511002410352
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3712  WP_001290288.1  E8XEP8  yhhY  162 aa N-acetyltransferase n.s. ●○○○○ -0.1 -0.0974188389224476
Vibrio parahaemolyticus RIMD 2210633  VPA_0219  BAC61562.1  Q87JM9  144 aa hypothetical protein n.s. ●○○○○ -0.1 -0.097133748894559
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2627  CBW18729.1  A0A0H3NEP1  tyrA  355 aa chorismate mutase/prephenate dehydrogenase n.s. ●○○○○ -0.1 -0.0970519005588076
Vibrio parahaemolyticus RIMD 2210633  VPA_0469  BAC61812.1  Q87IY7  263 aa hypothetical protein n.s. ●○○○○ -0.1 -0.0969518704056926
Acinetobacter baumannii ATCC 17978  A1S_1618  ABO12045.2  221 aa hypothetical protein n.s. ●○○○○ -0.1 -0.0969354582297854
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4741  AIK83275.1  364 aa sulfate ABC transporter, ATP-binding family protein n.s. ●○○○○ -0.1 -0.0969294506424511
Escherichia coli CFT073  c1301  AAN79774.1  P0AE96  csgE  129 aa Curli production assembly/transport component csgE precursor n.s. ●○○○○ -0.1 -0.0969282519293925
Escherichia coli CFT073  c4163  AAN82601.1  A0A0H2VBE5  yrfB  146 aa Hypothetical protein yrfB n.s. ●○○○○ -0.1 -0.0968822585319705
Vibrio parahaemolyticus RIMD 2210633  VP_2341  BAC60603.1  Q87MB6  185 aa hypothetical protein n.s. ●○○○○ -0.1 -0.0968629223731511
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4141  CBW20229.2  A0A0H3NVA9  gtrAb  108 aa hypothetical phage glycosyl transferase n.s. ●○○○○ -0.1 -0.0968203828275397
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0727  WP_000088019.1  E8XAT9  kdpB  682 aa potassium-transporting ATPase subunit KdpB n.s. ●○○○○ -0.1 -0.0967231488215463
Vibrio parahaemolyticus RIMD 2210633  VP_0561  BAC58824.1  Q87S63  clpB  857 aa ClpB protein n.s. ●○○○○ -0.1 -0.0966111272130338
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4591  AIK83125.1  432 aa H+ symporter family protein n.s. ●○○○○ -0.1 -0.0965934030111637
Vibrio parahaemolyticus RIMD 2210633  VPA_1157  BAC62500.1  Q87H08  308 aa electron transfer flavoprotein, alpha-subunit n.s. ●○○○○ -0.1 -0.0965594443394968
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1224  CBW17319.1  A0A0H3NAW7  yeaD  294 aa conserved hypothetical protein n.s. ●○○○○ -0.1 -0.0964798192886514
Vibrio parahaemolyticus RIMD 2210633  VP_1612  BAC59875.1  Q87PA5  rsmF  478 aa Sun/nucleolar protein family protein n.s. ●○○○○ -0.1 -0.0964584802803685
Serratia marcescens Strain UMH9  BVG96_12225  ASL98345.1  767 aa phosphoglycerol transferase I n.s. ●○○○○ -0.1 -0.096428781361858
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0358  CBW16458.1  A0A0H3NHZ7  334 aa AraC-family transcriptional regulator n.s. ●○○○○ -0.1 -0.0963435060851507
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2918  WP_000872348.1  E8XK24  tctE  471 aa sensor histidine kinase n.s. ●○○○○ -0.1 -0.0961848723606734
Serratia marcescens Strain UMH9  BVG96_22595  ASM00227.1  292 aa U32 family peptidase n.s. ●○○○○ -0.1 -0.0959663764992401
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0388  NP_232782.1  Q9KMG8  217 aa hypothetical protein n.s. ●○○○○ -0.1 -0.0959501744837877
Vibrio parahaemolyticus RIMD 2210633  VPA_1178  BAC62521.1  Q87GY7  333 aa transcriptional regulator, SorC family n.s. ●○○○○ -0.1 -0.0958824603637994
Vibrio parahaemolyticus RIMD 2210633  VP_1299  BAC59562.1  Q87Q51  225 aa conserved hypothetical protein n.s. ●○○○○ -0.1 -0.0958501459901118
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1295  AIK79918.1  304 aa lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase family protein n.s. ●○○○○ -0.1 -0.0957067340428464
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3081  AIK81666.1  153 aa putative acetyltransferase n.s. ●○○○○ -0.1 -0.0956937251213408
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0900  WP_000684361.1  E8XCM1  rimK  300 aa 30S ribosomal protein S6--L-glutamate ligase n.s. ●○○○○ -0.1 -0.0954066735366751
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4414  WP_000136400.1  E8X8Y2  lysC  449 aa lysine-sensitive aspartokinase 3 n.s. ●○○○○ -0.1 -0.0953847953267346
Streptococcus pyogenes M1 5448  SP5448_08355  WP_002982738.1  257 aa DeoR/GlpR transcriptional regulator n.s. ●○○○○ -0.1 -0.0952527379776336
Mycobacterium avium subsp. paratuberculosis K10  MAP_1775  AAS04092.1  Q73Z28  355 aa hypothetical protein n.s. ●○○○○ -0.1 -0.0952143155515374
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2132  AIK80737.1  55 aa hypothetical protein n.s. ●○○○○ -0.1 -0.0951194109542844
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0206  CBW16308.1  A0A0H3N7R6  yadS  207 aa hypothetical membrane protein n.s. ●○○○○ -0.1 -0.0950977631553285
Escherichia coli M12  CO715_03165  ATI04823.1  244 aa DNA-binding response regulator n.s. ●○○○○ -0.1 -0.0950520712687644
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2047  NP_231681.1  Q9KQF1  226 aa short chain dehydrogenase n.s. ●○○○○ -0.09 -0.0949473516212103
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1855  CBW17949.1  A0A0H3NMF8  cheW  167 aa purine binding chemotaxis protein n.s. ●○○○○ -0.09 -0.0949418970467215
Acinetobacter baumannii ATCC 17978  A1S_3217  ABO13608.2  1052 aa RND divalent metal cation efflux transporter n.s. ●○○○○ -0.09 -0.0948148193911306
Streptococcus pyogenes M1 5448  SP5448_05395  WP_002989837.1  382 aa AI-2E family transporter n.s. ●○○○○ -0.09 -0.0947720697286012
Acinetobacter baumannii ATCC 17978  A1S_2043  ABO12470.2  445 aa putative iron-regulated membrane protein n.s. ●○○○○ -0.09 -0.0946674709999925
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1467  WP_002856543.1  A0A0H3PDL2  ctsD  470 aa pilus (MSHA type) biogenesis protein MshL n.s. ●○○○○ -0.09 -0.0945880471573
Serratia marcescens Strain UMH9  BVG96_11735  ASL98253.1  727 aa hypothetical protein n.s. ●○○○○ -0.09 -0.0945675374131059
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2125  CBW18221.1  A0A0H3NNE5  104 aa conserved hypothetical protein n.s. ●○○○○ -0.09 -0.0945152983082507
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3166  WP_000665977.1  E8X9J1  yqeF  392 aa acetyl-CoA C-acetyltransferase n.s. ●○○○○ -0.09 -0.0943520356962153
Escherichia coli CFT073  c4971  AAN83397.1  A0A0H2VFL6  aceB  539 aa Malate synthase A n.s. ●○○○○ -0.09 -0.0942451326110128
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1182  CBW17277.1  A0A0H3NFR3  cspH  70 aa cold shock protein (CspH) n.s. ●○○○○ -0.09 -0.0941174232176664
Mycobacterium avium subsp. paratuberculosis K10  MAP_3134c  AAS05682.1  Q73V80  184 aa hypothetical protein n.s. ●○○○○ -0.09 -0.0939951239702354
Acinetobacter baumannii ATCC 17978  A1S_0509  ABO10962.1  42 aa putative acyl carrier protein n.s. ●○○○○ -0.09 -0.0939116816439676
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5110  AIK83636.1  300 aa integrase core domain protein n.s. ●○○○○ -0.09 -0.0938776219506658
Streptococcus pyogenes M1 5448  SP5448_08360  WP_002988079.1  95 aa DNA-damage-inducible protein J n.s. ●○○○○ -0.09 -0.0938107332305364
Acinetobacter baumannii ATCC 17978  A1S_0931  ABO11363.1  145 aa high-affinity choline transporter (BCCT family) n.s. ●○○○○ -0.09 -0.0936458857729142
Serratia marcescens Strain UMH9  BVG96_17680  ASL99339.1  159 aa hypothetical protein n.s. ●○○○○ -0.09 -0.0935388809709863
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0980  CBW17076.1  A0A0H3NJV5  1017 aa Tape Measure n.s. ●○○○○ -0.09 -0.093435281890713
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0229  NP_229886.1  Q9KVB7  309 aa hypothetical protein n.s. ●○○○○ -0.09 -0.0934186162019428
Mycobacterium avium subsp. paratuberculosis K10  MAP_3418  AAS05968.1  Q73UF0  149 aa hypothetical protein n.s. ●○○○○ -0.09 -0.0933022887892515
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