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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_17405  ATI07339.1  140 aa L-fucose mutarotase 0.035 ●○○○○ -0.29 -0.286589112349219
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2617  AIK81211.1  394 aa 4-hydroxybenzoate 3-monooxygenase 2.2e-16 ●○○○○ -0.29 -0.286515210261699
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0906  NP_233291.1  Q9KL42  578 aa methyl-accepting chemotaxis protein 0.016 ●○○○○ -0.29 -0.285469460374579
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1827  WP_000406435.1  E8X8H6  nhaB  514 aa Na(+)/H(+) antiporter NhaB 0.02 ●○○○○ -0.29 -0.285323008402504
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3056  AIK81641.1  246 aa azlC family protein 4.4e-11 ●○○○○ -0.28 -0.283429711087017
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2865  AIK81454.1  224 aa opacity-associated A N-terminal motif family protein 0.0017 ●○○○○ -0.28 -0.282774170960001
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2838  AIK81427.1  445 aa L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase <1e-323 ●○○○○ -0.28 -0.282677712207012
Escherichia coli M12  CO715_11805  ATI06329.1  449 aa two-component sensor histidine kinase 5.5e-6 ●○○○○ -0.28 -0.282624838078491
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2072  NP_231704.1  Q9KQC8  939 aa peptidase insulinase family protein 0.0011 ●○○○○ -0.28 -0.282288790238343
Escherichia coli M12  CO715_00860  ATI04411.1  229 aa transcriptional regulator 4.8e-19 ●○○○○ -0.28 -0.281998900035744
Porphyromonas gingivalis ATCC 33277  PGN_0648  WP_039417319.1  B2RIH2  347 aa endonuclease 8.2e-8 ●○○○○ -0.28 -0.281909810719098
Porphyromonas gingivalis ATCC 33277  PGN_0648  WP_021662541.1  B2RIH2  164 aa hypothetical protein 8.2e-8 ●○○○○ -0.28 -0.281909810719098
Porphyromonas gingivalis ATCC 33277  PGN_0648  WP_039417317.1  B2RIH2  88 aa hypothetical protein 8.2e-8 ●○○○○ -0.28 -0.281909810719098
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3871  AIK82421.1  325 aa yrbG CaCA transporter <1e-323 ●○○○○ -0.28 -0.281517099006905
Escherichia coli M12  CO715_04300  ATI05035.1  631 aa phosphomethylpyrimidine synthase 4.6e-16 ●○○○○ -0.28 -0.281372961992998
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2759  NP_232385.1  Q9KNI0  fadA  387 aa 3-ketoacyl-CoA thiolase 0.0012 ●○○○○ -0.28 -0.281086972899982
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0629  NP_230278.2  Q9KU94  1039 aa multidrug resistance protein 0.0013 ●○○○○ -0.28 -0.280424265353675
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0702  NP_233089.1  Q9KLP1  382 aa iron-containing alcohol dehydrogenase 0.023 ●○○○○ -0.28 -0.280250306421401
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0902  NP_233287.1  Q9KL46  278 aa hypothetical protein 0.011 ●○○○○ -0.28 -0.280040040240725
Escherichia coli M12  CO715_07930  ATI05645.1  210 aa DNA-binding response regulator 6.3e-20 ●○○○○ -0.28 -0.279912439893255
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2698  NP_232326.1  Q9KNN3  483 aa aspartate ammonia-lyase 0.036 ●○○○○ -0.28 -0.279866881327752
Escherichia coli M12  CO715_10135  ATI06031.1  142 aa protein TolA 6.5e-9 ●○○○○ -0.28 -0.279703793879007
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1969  AIK80575.1  422 aa amidase, hydantoinase/carbamoylase family protein 4.5e-8 ●○○○○ -0.28 -0.279418312064731
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3752  AIK82308.1  161 aa type IV leader peptidase family protein 3.6e-6 ●○○○○ -0.28 -0.278589228331874
Escherichia coli M12  CO715_18460  ATI07526.1  65 aa inovirus Gp2 family protein 3.5e-18 ●○○○○ -0.28 -0.278451917793513
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0863  NP_233249.1  Q9KL83  volA  796 aa lipase 0.0077 ●○○○○ -0.28 -0.278204446203439
Acinetobacter baumannii ATCC 17978  A1S_3327  ABO13716.2  662 aa dihydrolipoamide S-acetyltransferase E2 component of the pyruvate dehydrogenase complex 0.05 ●○○○○ -0.28 -0.277630456438427
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0727  NP_233114.1  Q9KLL6  cobQ  484 aa cobyric acid synthase 0.016 ●○○○○ -0.28 -0.276636740098512
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2814  AIK81403.1  439 aa PTS system, cellobiose-specific IIC component 7.8e-16 ●○○○○ -0.28 -0.276279490217184
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3432  AIK81988.1  497 aa H+ antiporter-2 family protein <1e-323 ●○○○○ -0.28 -0.276124907071236
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3850  AIK82400.1  164 aa stringent starvation B family protein 0.00033 ●○○○○ -0.28 -0.276105549526763
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1905  NP_231539.1  Q9KQU3  374 aa alanine dehydrogenase 1.4e-5 ●○○○○ -0.28 -0.27605629947641
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0759  NP_233145.1  Q9KLI5  243 aa arginine ABC transporter substrate-binding protein 5.6e-7 ●○○○○ -0.28 -0.275537884838646
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2619  AIK81213.1  258 aa hypothetical protein 1.2e-6 ●○○○○ -0.28 -0.27532199135008
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3399  AIK81956.1  119 aa hypothetical protein <1e-323 ●○○○○ -0.28 -0.275144127170017
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1540  NP_231180.2  Q9KRU4  norM  457 aa multidrug efflux protein 8.3e-5 ●○○○○ -0.27 -0.274988571198552
Escherichia coli M12  CO715_12840  ATI06517.1  711 aa polyribonucleotide nucleotidyltransferase 6.0e-5 ●○○○○ -0.27 -0.274904935551283
Escherichia coli M12  CO715_01460  ATI04514.1  119 aa fumarate reductase subunit D 0.0018 ●○○○○ -0.27 -0.274904935551283
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1629  NP_231266.1  Q9KRL1  836 aa hypothetical protein 0.037 ●○○○○ -0.27 -0.274687593254838
Acinetobacter baumannii ATCC 17978  A1S_0920  ABO11352.1  637 aa hypothetical protein 0.041 ●○○○○ -0.27 -0.274416515859538
Escherichia coli M12  CO715_21745  ATI08120.1  826 aa fimbrial biogenesis outer membrane usher protein 2.6e-296 ●○○○○ -0.27 -0.274278997508536
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2395  NP_232025.1  Q9KPH3  157 aa hypothetical protein 2.2e-5 ●○○○○ -0.27 -0.27389373189951
Porphyromonas gingivalis ATCC 33277  PGN_0068  WP_012457213.1  B2RGU2  195 aa hypothetical protein <1e-323 ●○○○○ -0.27 -0.273845580680675
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1059  NP_230704.1  Q9KT46  247 aa short chain dehydrogenase 0.00093 ●○○○○ -0.27 -0.273841963537891
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0609  NP_232998.1  Q9KLY2  60 aa hypothetical protein 0.00012 ●○○○○ -0.27 -0.273742576343975
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1304  NP_230949.1  Q9KSF2  505 aa fumarate hydratase, class I 8.2e-5 ●○○○○ -0.27 -0.273729022585719
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3549  AIK82105.1  539 aa ABC transporter family protein 3.6e-14 ●○○○○ -0.27 -0.273651774228328
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0942  NP_230589.1  Q9KTG0  117 aa hypothetical protein 0.00095 ●○○○○ -0.27 -0.273197981791697
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0093  NP_229752.2  Q9KVP8  plsB  808 aa glycerol-3-phosphate acyltransferase 0.0015 ●○○○○ -0.27 -0.272719875250343
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0053  NP_232454.2  Q9KNB2  deoD2  236 aa purine nucleoside phosphorylase 0.048 ●○○○○ -0.27 -0.272448531420078
Escherichia coli M12  CO715_08450  ATI05739.1  222 aa arginine transporter permease subunit ArtM 1.3e-58 ●○○○○ -0.27 -0.272192537366048
Porphyromonas gingivalis ATCC 33277  PGN_0794  WP_012457784.1  B2RIW8  368 aa DUF2891 domain-containing protein <1e-323 ●○○○○ -0.27 -0.271954505675023
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3413  AIK81970.1  448 aa sugar (and other) transporter family protein 6.7e-8 ●○○○○ -0.27 -0.271953822678993
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1844  NP_231478.1  Q9KR03  541 aa cytochrome d ubiquinol oxidase subunit I 2.3e-6 ●○○○○ -0.27 -0.271831344050223
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1077  NP_230722.1  Q9KT28  162 aa hypothetical protein 0.0011 ●○○○○ -0.27 -0.271806802115799
Escherichia coli M12  CO715_06460  ATI05389.1  216 aa DNA-binding response regulator 1.5e-13 ●○○○○ -0.27 -0.27177524533755
Escherichia coli M12  CO715_19635  ATI07735.1  397 aa tryptophan synthase subunit beta 4.2e-11 ●○○○○ -0.27 -0.271566599323301
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4936  AIK83462.1  506 aa ABC transporter family protein <1e-323 ●○○○○ -0.27 -0.271366902361865
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3955  AIK82503.1  200 aa helix-turn-helix family protein 0.00019 ●○○○○ -0.27 -0.271113074418181
Escherichia coli M12  CO715_23240  ATI08383.1  419 aa S-methyl-5-thioribose kinase 2.2e-9 ●○○○○ -0.27 -0.269688785195061
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3236  AIK81797.1  293 aa eamA-like transporter family protein <1e-323 ●○○○○ -0.27 -0.269664461540707
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2120  AIK80725.1  366 aa arabinogalactan endo-1,4-beta-galactosidase <1e-323 ●○○○○ -0.27 -0.269601667074621
Escherichia coli M12  CO715_19595  ATI07729.1  291 aa 23S rRNA pseudouridylate synthase B 0.018 ●○○○○ -0.27 -0.269271493166564
Escherichia coli M12  CO715_00690  ATI04379.1  463 aa hexose phosphate transporter 0.0045 ●○○○○ -0.27 -0.269062847152315
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4787  AIK83314.1  440 aa 47 kDa outer membrane protein <1e-323 ●○○○○ -0.27 -0.268609534829842
Escherichia coli M12  CO715_18585  ATI07546.1  280 aa cytoplasmic protein 2.0e-8 ●○○○○ -0.27 -0.268228263095319
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2861  AIK81450.1  323 aa eamA-like transporter family protein <1e-323 ●○○○○ -0.27 -0.268048854554371
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4667  AIK83201.1  396 aa phage integrase family protein 5.0e-7 ●○○○○ -0.27 -0.267629828273028
Escherichia coli M12  CO715_09825  ATI05980.1  487 aa anion permease 0.00083 ●○○○○ -0.27 -0.267393679038324
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2102  AIK80707.1  303 aa hypothetical protein <1e-323 ●○○○○ -0.27 -0.267388971240569
Escherichia coli M12  CO715_24520  ATI08595.1  187 aa hydrolase 1.1e-6 ●○○○○ -0.27 -0.267185033024075
Escherichia coli M12  CO715_24245  ATI08548.1  256 aa SAM-dependent methyltransferase 1.7e-20 ●○○○○ -0.27 -0.265933156938582
Escherichia coli M12  CO715_10865  ATI06154.1  370 aa hypothetical protein 3.4e-29 ●○○○○ -0.27 -0.265515864910084
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0370  NP_230024.1  Q9KUY8  269 aa hypothetical protein 0.0017 ●○○○○ -0.27 -0.265198323915864
Escherichia coli M12  CO715_02850  ATI04769.1  338 aa phosphate acetyltransferase 0.0065 ●○○○○ -0.26 -0.264889926867337
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0795  NP_233181.1  Q9KLF1  318 aa resolvase 4.5e-5 ●○○○○ -0.26 -0.263972244350285
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3685  AIK82240.1  697 aa 4-alpha-glucanotransferase <1e-323 ●○○○○ -0.26 -0.263476496881013
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0349  NP_230003.1  Q9KV09  hflK  395 aa HflK protein 7.7e-5 ●○○○○ -0.26 -0.26346881482423
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2539  NP_232167.1  Q9KP40  330 aa thiamine transporter substrate binding subunit 0.0067 ●○○○○ -0.26 -0.263344583886103
Escherichia coli M12  CO715_06805  ATI05449.1  114 aa glycine zipper family protein 2.4e-27 ●○○○○ -0.26 -0.263220758753347
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4927  AIK83453.1  288 aa LYSR-type transcriptional regulator 0.001 ●○○○○ -0.26 -0.262838442642123
Escherichia coli M12  CO715_19865  ATI08871.1  516 aa cyclic diguanylate phosphodiesterase 6.8e-21 ●○○○○ -0.26 -0.262803466724849
Escherichia coli M12  CO715_21800  ATI08131.1  425 aa MFS transporter 0.033 ●○○○○ -0.26 -0.262803466724849
Porphyromonas gingivalis ATCC 33277  PGN_1252  WP_012458141.1  B2RK76  382 aa iron-containing alcohol dehydrogenase 0.00011 ●○○○○ -0.26 -0.262182593265797
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3598  AIK82153.1  299 aa putative transcriptional regulator LYSR-type <1e-323 ●○○○○ -0.26 -0.262104619084652
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4230  AIK82775.1  870 aa type VII secretion system (T7SS), usher family protein <1e-323 ●○○○○ -0.26 -0.261770991495134
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2164  NP_231795.1  Q9KQ40  484 aa hypothetical protein 0.00078 ●○○○○ -0.26 -0.261173470504978
Escherichia coli M12  CO715_18900  ATI07602.1  499 aa L-asparagine permease 1.3e-43 ●○○○○ -0.26 -0.259673776511116
Porphyromonas gingivalis ATCC 33277  PGN_1044  WP_012457981.1  B2RJL8  564 aa alpha-amylase 0.0003 ●○○○○ -0.26 -0.259632622967507
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2424  AIK81021.1  293 aa glutamyl-queuosine tRNA(Asp) synthetase <1e-323 ●○○○○ -0.26 -0.259229158814532
Escherichia coli M12  CO715_01165  ATI04463.1  296 aa ribose ABC transporter substrate-binding protein RbsB 5.3e-29 ●○○○○ -0.26 -0.258839192454121
Escherichia coli M12  CO715_23020  ATI08345.1  486 aa fructuronate reductase 1.4e-8 ●○○○○ -0.26 -0.258004608397125
Escherichia coli M12  CO715_09815  ATI05978.1  183 aa apo-citrate lyase phosphoribosyl-dephospho-CoA transferase 3.6e-16 ●○○○○ -0.26 -0.257795962382876
Escherichia coli M12  CO715_21890  ATI08148.1  1040 aa multidrug resistance protein MdtB 4.3e-8 ●○○○○ -0.26 -0.257587316368627
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1899  AIK80505.1  202 aa methylthioribulose-1-phosphate dehydratase 1.5e-8 ●○○○○ -0.26 -0.257379731260237
Escherichia coli M12  CO715_05185  ATI05177.1  74 aa hypothetical protein 3.9e-7 ●○○○○ -0.26 -0.25717002434013
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2052  AIK80658.1  425 aa adiC 0.0018 ●○○○○ -0.26 -0.257110653948169
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2819  AIK81408.1  154 aa anaerobic ribonucleoside-triphosphate reductase activating protein 1.8e-6 ●○○○○ -0.26 -0.256867498594394
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1153  AIK79776.1  381 aa amidohydrolase family protein 0.033 ●○○○○ -0.26 -0.256712997238804
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3384  AIK81941.1  442 aa D-serine ammonia-lyase <1e-323 ●○○○○ -0.26 -0.256524945030451
Retrieved entries 6,201–6,300 out of 36,363 total in 7.7 ms (Link to these results)