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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4400  AIK82943.1  348 aa M42 glutamyl aminopeptidase family protein <1e-323 ●○○○○ -0.1 -0.0992194470225671
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2805  AIK81394.1  324 aa fructosamine deglycase frlB <1e-323 ●○○○○ -0.1 -0.0989217346843636
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3578  AIK82133.1  1350 aa TPR repeat family protein <1e-323 ●○○○○ -0.1 -0.0986246014785958
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3705  AIK82260.1  257 aa hypothetical protein 5.0e-15 ●○○○○ -0.1 -0.0980851598742563
Escherichia coli M12  CO715_13880  ATI06700.1  286 aa NAD(P)-dependent oxidoreductase 2.2e-25 ●○○○○ -0.1 -0.0979731154682485
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2122  AIK80727.1  408 aa binding-protein-dependent transport system innermembrane component family protein 1.5e-14 ●○○○○ -0.1 -0.0974251783639534
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2627  AIK81221.1  349 aa SIS domain protein 1.2e-14 ●○○○○ -0.1 -0.0973689493631157
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2308  AIK80912.1  325 aa taurine catabolism dioxygenase TauD, TfdA familyprotein 3.7e-9 ●○○○○ -0.1 -0.0973156962348697
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3051  AIK81636.1  396 aa malE 1.0e-10 ●○○○○ -0.1 -0.0968809782428101
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4168  AIK82714.1  486 aa 3-octaprenyl-4-hydroxybenzoate carboxy-lyase family protein <1e-323 ●○○○○ -0.1 -0.0952753372400243
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4354  AIK82897.1  366 aa 23S rRNA 2'-O-ribose C2498 methyltransferase 0.029 ●○○○○ -0.09 -0.094804328486226
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2804  AIK81393.1  277 aa pfkB carbohydrate kinase family protein <1e-323 ●○○○○ -0.09 -0.0947550197241692
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2538  NP_232166.1  Q9KP41  530 aa thiamine transporter membrane protein 2.3e-5 ●○○○○ -0.09 -0.0942897729244335
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1508  AIK80128.1  405 aa integral membrane, PqiA family protein 2.6e-6 ●○○○○ -0.09 -0.0940356652067978
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2049  AIK80655.1  505 aa lysine--tRNA ligase 2.2e-16 ●○○○○ -0.09 -0.0934564222544082
Escherichia coli M12  CO715_17245  ATI07309.1  484 aa FAD-binding oxidoreductase 2.0e-18 ●○○○○ -0.09 -0.0927569651120269
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1848  AIK80454.1  292 aa transporter associated domain protein 0.0018 ●○○○○ -0.09 -0.0925658866540386
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3554  AIK82110.1  323 aa glyoxylate/hydroxypyruvate reductase B 2.3e-10 ●○○○○ -0.09 -0.0924231117273065
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4831  AIK83358.1  219 aa HAD hydrolase, IA, variant 3 family protein 0.012 ●○○○○ -0.09 -0.0916108247903955
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2085  NP_231717.1  Q9KQB5  sucC  388 aa succinyl-CoA synthetase subunit beta 0.00055 ●○○○○ -0.09 -0.0914403874623471
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1941  AIK80546.1  320 aa hypothetical protein <1e-323 ●○○○○ -0.09 -0.0911933585529544
Porphyromonas gingivalis ATCC 33277  PGN_0318  WP_080504391.1  B2RHJ2  135 aa hypothetical protein 0.00032 ●○○○○ -0.09 -0.0907183884601181
Porphyromonas gingivalis ATCC 33277  PGN_0318  WP_012457422.1  B2RHJ2  468 aa precorrin-3B C(17)-methyltransferase 0.00032 ●○○○○ -0.09 -0.0907183884601181
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1454  NP_231097.1  H9L4R5  359 aa RstA1 protein 0.0096 ●○○○○ -0.09 -0.0896334803556596
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3593  AIK82148.1  309 aa ketodeoxygluconokinase <1e-323 ●○○○○ -0.09 -0.0896222751184185
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2597  AIK81194.1  357 aa patatin-like phospholipase family protein 0.00013 ●○○○○ -0.09 -0.0895169685514619
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2569  NP_232197.1  Q9KP10  160 aa hypothetical protein 3.3e-5 ●○○○○ -0.09 -0.0894726073076199
Escherichia coli M12  CO715_19220  ATI07660.1  311 aa tRNA 2-thiocytidine(32) synthetase TtcA 1.7e-14 ●○○○○ -0.09 -0.0894186288840451
Escherichia coli M12  CO715_01635  ATI04546.1  548 aa fumarate hydratase 0.016 ●○○○○ -0.09 -0.0890013368555474
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2155  AIK80760.1  432 aa trigger factor <1e-323 ●○○○○ -0.09 -0.0889899876288469
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3802  AIK82352.1  1036 aa acrB RND-type permease <1e-323 ●○○○○ -0.09 -0.0889567752052008
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3052  AIK81637.1  496 aa malF 0.00074 ●○○○○ -0.09 -0.0887890813588676
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2977  AIK81562.1  761 aa HAMP domain protein 7.0e-7 ●○○○○ -0.09 -0.08847478557225
Escherichia coli M12  CO715_12805  ATI06510.1  335 aa LLM class flavin-dependent oxidoreductase 0.00013 ●○○○○ -0.09 -0.0883753988128008
Escherichia coli M12  CO715_03400  ATI04865.1  174 aa fimbrial protein 0.0053 ●○○○○ -0.09 -0.0883753988128008
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3099  AIK81680.1  211 aa thiamine-phosphate pyrophosphorylase <1e-323 ●○○○○ -0.09 -0.0882943590375577
Escherichia coli M12  CO715_23950  ATI08493.1  408 aa RtcB family protein 2.7e-7 ●○○○○ -0.09 -0.0879581067843031
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3677  AIK82232.1  815 aa glgP <1e-323 ●○○○○ -0.09 -0.0877587267349023
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0361  NP_230015.1  Q9KUZ7  fusA1  698 aa elongation factor G 0.011 ●○○○○ -0.09 -0.0871775168314144
Escherichia coli M12  CO715_15335  ATI06965.1  104 aa L-rhamnose mutarotase 4.6e-5 ●○○○○ -0.09 -0.0864975846845611
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1770  NP_231405.1  Q9KR73  687 aa hypothetical protein 2.4e-5 ●○○○○ -0.09 -0.0863512248207738
Escherichia coli M12  CO715_15730  ATI07031.1  413 aa uroporphyrinogen-III C-methyltransferase 0.003 ●○○○○ -0.09 -0.0858716466418145
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2657  AIK81251.1  452 aa 4-hydroxyphenylacetate permease <1e-323 ●○○○○ -0.09 -0.0858310602885524
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0810  NP_230459.1  Q9KTS8  171 aa hypothetical protein 0.00042 ●○○○○ -0.09 -0.0856923356117306
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0816  NP_230465.1  Q9KTS2  60 aa hypothetical protein 0.029 ●○○○○ -0.08 -0.0846842163550785
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3498  AIK82054.1  329 aa glycosyl transferase 2 family protein <1e-323 ●○○○○ -0.08 -0.0844681052045736
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3990  AIK82538.1  204 aa bacterial regulatory, luxR family protein 0.016 ●○○○○ -0.08 -0.08444167241047
Escherichia coli M12  CO715_00695  ATI04380.1  439 aa MFS transporter family glucose-6-phosphate receptor UhpC 0.02 ●○○○○ -0.08 -0.0844111245420724
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3730  AIK82284.1  406 aa argD 2.6e-13 ●○○○○ -0.08 -0.0841842210889648
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0365  NP_230019.1  Q9KUZ3  158 aa bacterioferritin 0.045 ●○○○○ -0.08 -0.0841712375636212
Escherichia coli M12  CO715_22920  ATI08327.1  113 aa endoribonuclease SymE 1.3e-13 ●○○○○ -0.08 -0.0837851864993259
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1736  NP_231372.1  Q9KRA6  bpt  233 aa arginyl-tRNA-protein transferase 0.047 ●○○○○ -0.08 -0.083764644159214
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2702  AIK81292.1  88 aa hypothetical protein 4.4e-5 ●○○○○ -0.08 -0.0837434085307747
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4073  AIK82620.1  869 aa type VII secretion system (T7SS), usher family protein 1.3e-12 ●○○○○ -0.08 -0.0828070013220868
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0021  NP_229680.2  Q9KVW7  glyQ  305 aa glycyl-tRNA synthetase subunit alpha 0.00063 ●○○○○ -0.08 -0.0823679347921273
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1401  NP_231044.1  Q9KS59  cheB3  358 aa protein-glutamate methylesterase CheB 0.00062 ●○○○○ -0.08 -0.0823539628200586
Escherichia coli M12  CO715_12240  ATI06409.1  361 aa dTDP-glucose 4,6-dehydratase 0.0039 ●○○○○ -0.08 -0.0823246643995839
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2978  AIK81563.1  506 aa ABC transporter family protein 1.6e-10 ●○○○○ -0.08 -0.0822048223166335
Escherichia coli M12  CO715_13225  ATI06584.1  655 aa p-hydroxybenzoic acid efflux pump subunit AaeB 1.5e-21 ●○○○○ -0.08 -0.082116018385335
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1572  AIK80192.1  80 aa specificity factor for ClpA-ClpP chaperone-protease complex 0.0011 ●○○○○ -0.08 -0.0820860097806792
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1244  NP_230889.1  Q9KSL2  btuC  335 aa vtamin B12-transporter permease 0.015 ●○○○○ -0.08 -0.0819187908757714
Escherichia coli M12  CO715_18915  ATI07605.1  700 aa TonB-dependent siderophore receptor 0.00012 ●○○○○ -0.08 -0.0819073723710861
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1394  NP_231038.1  Q9KS65  411 aa methyl-accepting chemotaxis protein 0.00043 ●○○○○ -0.08 -0.0814679037332422
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0897  NP_233282.1  Q9KL51  pgl  238 aa 6-phosphogluconolactonase 0.025 ●○○○○ -0.08 -0.0813607037908215
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1947  AIK80554.1  418 aa mechanosensitive ion channel family protein 1.1e-5 ●○○○○ -0.08 -0.0812385081035838
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0870  NP_233256.1  Q9KL77  316 aa D-alanyl-D-alanine endopeptidase 0.00029 ●○○○○ -0.08 -0.0811648431601461
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3652  AIK82207.1  425 aa branched-chain amino acid transport system / permease component family protein <1e-323 ●○○○○ -0.08 -0.0810207956663028
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2584  AIK81181.1  645 aa soluble lytic murein transglycosylase <1e-323 ●○○○○ -0.08 -0.0807717803932805
Escherichia coli M12  CO715_24620  ATI08611.1  383 aa L-threonine dehydrogenase 4.2e-16 ●○○○○ -0.08 -0.080655496285593
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4866  AIK83393.1  392 aa glycerol-3-phosphate dehydrogenase, anaerobic, Csubunit <1e-323 ●○○○○ -0.08 -0.0805431763675176
Escherichia coli M12  CO715_08965  ATI05835.1  427 aa acyl-CoA thioesterase 1.7e-16 ●○○○○ -0.08 -0.0804468502713441
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3938  AIK82486.1  328 aa glutathione S-transferase, C-terminal domain protein <1e-323 ●○○○○ -0.08 -0.0801779795245427
Escherichia coli M12  CO715_20890  ATI07965.1  365 aa flagellar biosynthesis protein FlgA 0.037 ●○○○○ -0.08 -0.0798209122285975
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1771  NP_231406.1  Q9KR72  1220 aa hypothetical protein 0.014 ●○○○○ -0.08 -0.0791606282391095
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3723  AIK82278.1  196 aa major Facilitator Superfamily protein <1e-323 ●○○○○ -0.08 -0.0791563205886169
Escherichia coli M12  CO715_22505  ATI08257.1  327 aa dipeptide transport ATP-binding protein DppD 3.0e-23 ●○○○○ -0.08 -0.0783603901288555
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1173  NP_230818.1  Q9KST3  trpG  203 aa anthranilate synthase component II 5.1e-5 ●○○○○ -0.08 -0.0781229242666636
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0465  NP_232857.1  Q9KMA9  134 aa hypothetical protein 1.2e-6 ●○○○○ -0.08 -0.0776346849254732
Escherichia coli M12  CO715_08885  ATI05819.1  129 aa hypothetical protein 6.5e-6 ●○○○○ -0.08 -0.07752580607186
Escherichia coli M12  CO715_06690  ATI05429.1  356 aa alanine racemase 5.0e-5 ●○○○○ -0.08 -0.0768998680291135
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0813  NP_230462.1  Q9KTS5  192 aa tellurite resistance protein-like protein 0.0041 ●○○○○ -0.08 -0.0765030383414155
Escherichia coli M12  CO715_10630  ATI06112.1  285 aa efflux transporter periplasmic adaptor subunit 0.0016 ●○○○○ -0.08 -0.0764825760006157
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0553  NP_230204.1  Q9KUG8  153 aa hypothetical protein 0.018 ●○○○○ -0.08 -0.0762262400429028
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1623  NP_231262.1  Q9KRL4  nspC  387 aa carboxynorspermidine decarboxylase 0.0036 ●○○○○ -0.08 -0.0761469971912253
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4078  AIK82624.1  712 aa orn/Lys/Arg decarboxylase, N-terminal domain protein <1e-323 ●○○○○ -0.08 -0.075750233620096
Porphyromonas gingivalis ATCC 33277  PGN_0200  WP_012457322.1  B2RH74  296 aa TraB/GumN family protein 2.2e-16 ●○○○○ -0.08 -0.0756811968277335
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3430  AIK81987.1  215 aa bacterial regulatory, tetR family protein 3.6e-12 ●○○○○ -0.08 -0.0752324037527843
Escherichia coli M12  CO715_08570  ATI05763.1  198 aa undecaprenyl-diphosphate phosphatase 2.0e-5 ●○○○○ -0.08 -0.0750220539008737
Escherichia coli M12  CO715_04585  ATI05077.1  334 aa mononuclear molybdenum enzyme YedY 2.3e-56 ●○○○○ -0.07 -0.074604761872376
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2762  AIK81352.1  67 aa prophage CP4-57 regulatory family protein 0.032 ●○○○○ -0.07 -0.0744503004187099
Escherichia coli M12  CO715_01615  ATI04543.1  543 aa sensor histidine kinase 1.7e-12 ●○○○○ -0.07 -0.0743961158581272
Escherichia coli M12  CO715_07110  ATI05505.1  63 aa hypothetical protein 1.3e-9 ●○○○○ -0.07 -0.0743961158581272
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4150  AIK82696.1  669 aa cytochrome C biogenesis transmembrane region family protein 9.9e-13 ●○○○○ -0.07 -0.0740255507679411
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5000  AIK83526.1  412 aa efflux transporter, RND family, MFP subunit 0.00044 ●○○○○ -0.07 -0.0738869360778529
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4822  AIK83349.1  120 aa dihydroneopterin triphosphate 2'-epimerase 6.0e-5 ●○○○○ -0.07 -0.0724690521491209
Porphyromonas gingivalis ATCC 33277  PGN_0581  WP_012457617.1  B2RIA5  494 aa DUF3945 domain-containing protein 2.7e-9 ●○○○○ -0.07 -0.0724298287882318
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1929  NP_231563.1  Q9KQR9  dctP  332 aa C4-dicarboxylate-binding protein 0.0055 ●○○○○ -0.07 -0.0723659659377274
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4185  AIK82730.1  203 aa ABC transporter family protein 0.00039 ●○○○○ -0.07 -0.0720519028284021
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2446  NP_232075.1  Q9KPC6  cca  403 aa multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 0.0014 ●○○○○ -0.07 -0.0716793528126065
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0923  NP_233308.2  Q9KL26  624 aa methyl-accepting chemotaxis protein 0.01 ●○○○○ -0.07 -0.0713181577119114
Retrieved entries 6,801–6,900 out of 36,363 total in 7.3 ms (Link to these results)