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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1055  AIK79678.1  45 aa hypothetical protein 2.7e-15 ○○○○○ 1.64 1.6354176113484
Escherichia coli M12  CO715_15950  ATI07072.1  387 aa acetyl-CoA C-acyltransferase FadA 0.00048 ○○○○○ 1.64 1.63566661692554
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2105  AIK80710.1  397 aa acrA Membrane Fusion Protein <1e-323 ○○○○○ 1.64 1.63584568662724
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1797  NP_231432.1  Q9KR49  153 aa hypothetical protein 0.0053 ○○○○○ 1.64 1.63765715747794
Mycobacterium avium subsp. paratuberculosis K10  MAP_2056c  AAS04373.1  Q73YA0  242 aa hypothetical protein 0.034 ○○○○○ 1.64 1.63896081385847
Mycobacterium avium subsp. paratuberculosis K10  MAP_3446c  AAS05996.1  Q73UC2  sigJ  295 aa SigJ 0.034 ○○○○○ 1.64 1.6395119158059
Escherichia coli O157:H7 str. EDL933  Z1410  AAG55540.1  904 aa sensor protein torS (regulator TorR) 0.047 ○○○○○ 1.64 1.63960122581552
Acinetobacter baumannii ATCC 17978  A1S_0230  ABO10705.2  515 aa phosphoglycerate mutase III cofactor independent 0.018 ○○○○○ 1.64 1.6400117678283
Mycobacterium avium subsp. paratuberculosis K10  MAP_2371c  AAS04688.1  Q73XD8  411 aa hypothetical protein 0.034 ○○○○○ 1.64 1.64100990756409
Mycobacterium avium subsp. paratuberculosis K10  MAP_0919  AAS03236.1  Q742B8  moaB2  185 aa MoaB2 0.034 ○○○○○ 1.64 1.64325504681598
Escherichia coli M12  CO715_14375  ATI06788.1  141 aa arsenate reductase (glutaredoxin) 7.1e-7 ○○○○○ 1.64 1.64484704155249
Mycobacterium avium subsp. paratuberculosis K10  MAP_3933c  AAS06483.1  Q73SY9  312 aa hypothetical protein 0.034 ○○○○○ 1.65 1.64524577148267
Mycobacterium avium subsp. paratuberculosis K10  MAP_4333  AAS06883.1  Q73RU5  542 aa hypothetical protein 0.034 ○○○○○ 1.65 1.64537928018617
Acinetobacter baumannii ATCC 17978  A1S_2349  ABO12768.2  292 aa 4-hydroxybenzoate octaprenyltransferase 0.0015 ○○○○○ 1.65 1.64588648567628
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1101  AIK79724.1  163 aa type VI secretion system effector, Hcp1 family protein <1e-323 ○○○○○ 1.65 1.64723505228362
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1693  AIK80313.1  304 aa 23S rRNA m6A1618 methyltransferase <1e-323 ○○○○○ 1.65 1.64850212255327
Mycobacterium avium subsp. paratuberculosis K10  MAP_2441c  AAS04758.1  Q73X68  420 aa hypothetical protein 0.034 ○○○○○ 1.65 1.64935460907225
Mycobacterium avium subsp. paratuberculosis K10  MAP_3794c  AAS06344.1  Q73TC4  160 aa hypothetical protein 0.034 ○○○○○ 1.65 1.64994428484738
Mycobacterium avium subsp. paratuberculosis K10  MAP_0284c  AAS02601.1  Q743L4  540 aa hypothetical protein 0.033 ○○○○○ 1.65 1.65156991829949
Mycobacterium avium subsp. paratuberculosis K10  MAP_1622c  AAS03939.1  Q73ZI1  302 aa hypothetical protein 0.033 ○○○○○ 1.65 1.65216756776442
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1290  AIK79913.1  337 aa diguanylate cyclase domain protein 3.2e-12 ○○○○○ 1.65 1.65220693963802
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2126  NP_231757.1  Q9KQ75  349 aa flagellar motor switch protein FliM 0.00045 ○○○○○ 1.65 1.65258683943262
Streptococcus pyogenes M1 5448  SP5448_00965  WP_002987915.1  880 aa DNA polymerase I 0.044 ○○○○○ 1.65 1.65332221835243
Mycobacterium avium subsp. paratuberculosis K10  MAP_3264c  AAS05812.1  Q73UV2  245 aa hypothetical protein 0.033 ○○○○○ 1.66 1.65553736799429
Escherichia coli M12  CO715_24325  ATI08562.1  174 aa type VI secretion system lipoprotein TssJ 0.032 ○○○○○ 1.66 1.65820038646442
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1710  AIK80330.1  377 aa ABC-2 type transporter family protein <1e-323 ○○○○○ 1.66 1.65889020748243
Porphyromonas gingivalis ATCC 33277  PGN_0675  WP_012457689.1  B2RIJ9  181 aa DJ-1 family protein <1e-323 ○○○○○ 1.66 1.66167208247419
Mycobacterium avium subsp. paratuberculosis K10  MAP_3748c  AAS06298.1  Q73TH0  402 aa IS1110 0.033 ○○○○○ 1.66 1.66259690408928
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3641  WP_000049249.1  E8XEH7  nirB  847 aa nitrite reductase large subunit 0.001 ○○○○○ 1.66 1.66268499488149
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3067  WP_001221538.1  E8XL55  surE  253 aa 5'/3'-nucleotidase SurE 0.0049 ○○○○○ 1.66 1.66419707992354
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3734  WP_000676957.1  E8XF79  livJ  365 aa branched-chain amino acid ABC transporter substrate-binding protein 0.0025 ○○○○○ 1.67 1.66505004604607
Acinetobacter baumannii ATCC 17978  A1S_3196  ABO13589.1  470 aa putative penicillin binding protein (PonA) 1.4e-13 ○○○○○ 1.67 1.66635803968128
Mycobacterium avium subsp. paratuberculosis K10  MAP_4187c  AAS06737.1  Q73S89  308 aa hypothetical protein 0.033 ○○○○○ 1.67 1.66707807962897
Streptococcus pyogenes M1 5448  SP5448_01285  WP_010921883.1  423 aa DNA recombination protein RmuC 0.03 ○○○○○ 1.67 1.66870360232147
Mycobacterium avium subsp. paratuberculosis K10  MAP_4034  AAS06584.1  Q73SN9  559 aa hypothetical protein 0.032 ○○○○○ 1.67 1.67063708175609
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1236  NP_230881.1  Q9KSM0  148 aa PilB-like protein 0.0036 ○○○○○ 1.67 1.67301035374272
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1097  AIK79720.1  258 aa hypothetical protein <1e-323 ○○○○○ 1.67 1.67348006901711
Mycobacterium avium subsp. paratuberculosis K10  MAP_0095c  AAS02412.1  Q744Z4  nuoI1  175 aa NuoI_1 0.032 ○○○○○ 1.67 1.67358786923587
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4740  AIK83274.1  291 aa sulfate ABC transporter, permease protein CysW <1e-323 ○○○○○ 1.67 1.67384626766798
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1084  AIK79707.1  292 aa bacterial regulatory helix-turn-helix, AraC family protein 7.3e-5 ○○○○○ 1.68 1.67502567879802
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1010  AIK79633.1  441 aa sugar (and other) transporter family protein 1.7e-10 ○○○○○ 1.68 1.67606537675734
Streptococcus pyogenes M1 5448  SP5448_09025  WP_010922746.1  674 aa PTS trehalose transporter subunit IIBC 0.033 ○○○○○ 1.68 1.67735563080405
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1329  AIK79952.1  410 aa peptidase T <1e-323 ○○○○○ 1.68 1.67804911798679
Mycobacterium avium subsp. paratuberculosis K10  MAP_0830c  AAS03147.1  Q742K5  516 aa hypothetical protein 0.032 ○○○○○ 1.68 1.67954343468166
Porphyromonas gingivalis ATCC 33277  PGN_0010  WP_012457167.1  B2RGN4  342 aa aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme <1e-323 ○○○○○ 1.68 1.68134875325529
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1554  AIK80174.1  246 aa pyruvate formate-lyase 1-activating enzyme 7.5e-9 ○○○○○ 1.68 1.68232728747241
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3696  AIK82251.1  239 aa ompR <1e-323 ○○○○○ 1.68 1.68345498931427
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3688  WP_000013008.1  E8XEM4  517 aa TROVE domain-containing protein 9.6e-5 ○○○○○ 1.68 1.6838983142387
Mycobacterium avium subsp. paratuberculosis K10  MAP_3896  AAS06446.1  Q73T23  mutT3  213 aa MutT3 0.032 ○○○○○ 1.68 1.68432283925232
Mycobacterium avium subsp. paratuberculosis K10  MAP_2631  AAS04948.1  Q73WM9  186 aa hypothetical protein 0.032 ○○○○○ 1.69 1.6860329054765
Porphyromonas gingivalis ATCC 33277  PGN_0226  WP_021677083.1  B2RHA0  401 aa hypothetical protein <1e-323 ○○○○○ 1.69 1.68680304126967
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2120  NP_231751.1  Q9KQ81  flhB  376 aa flagellar biosynthesis protein FlhB 1.8e-5 ○○○○○ 1.69 1.68939740433379
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0684  NP_230333.1  Q9KU45  144 aa FKBP-type peptidylprolyl isomerase 0.0016 ○○○○○ 1.69 1.69294300099252
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0610  WP_002854935.1  A0A0H3PB58  400 aa aspartate kinase 0.049 ○○○○○ 1.69 1.69310681381
Mycobacterium avium subsp. paratuberculosis K10  MAP_3978  AAS06528.1  Q73SU5  428 aa hypothetical protein 0.031 ○○○○○ 1.7 1.69520942441491
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0132  WP_002851769.1  A0A0H3PA70  proB  251 aa glutamate 5-kinase 0.049 ○○○○○ 1.7 1.69655395164
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5087  AIK83613.1  359 aa trbL/VirB6 plasmid conjugal transfer family protein <1e-323 ○○○○○ 1.7 1.69661821249261
Escherichia coli O157:H7 str. EDL933  Z0615  AAG54838.1  5188 aa putative RTX family exoprotein 0.042 ○○○○○ 1.7 1.69724361397248
Escherichia coli M12  CO715_05860  ATI08740.1  246 aa phage tail protein 3.6e-40 ○○○○○ 1.7 1.69846906721445
Mycobacterium avium subsp. paratuberculosis K10  MAP_1300  AAS03617.1  P60543  hisI  115 aa HisI2 0.031 ○○○○○ 1.7 1.70107869692009
Escherichia coli M12  CO715_14310  ATI06776.1  164 aa heme utilization cystosolic carrier protein HutX 9.4e-6 ○○○○○ 1.7 1.70118146539968
Acinetobacter baumannii ATCC 17978  A1S_0995  ABO11427.1  54 aa rubredoxin 1.1e-11 ○○○○○ 1.7 1.70233763649455
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5063  AIK83589.1  439 aa H+ symporter family protein <1e-323 ○○○○○ 1.7 1.70267865051893
Escherichia coli M12  CO715_11545  ATI06284.1  518 aa hypothetical protein 9.6e-6 ○○○○○ 1.7 1.70326792554217
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0216  WP_002857271.1  A0A0H3PIS1  69 aa alkylphosphonate utilization protein 0.049 ○○○○○ 1.7 1.70357660837
Mycobacterium avium subsp. paratuberculosis K10  MAP_4094c  AAS06644.1  Q73SH9  recC  1096 aa RecC 0.031 ○○○○○ 1.7 1.70411873979794
Mycobacterium avium subsp. paratuberculosis K10  MAP_0019c  AAS02336.1  Q744R3  pbpA  492 aa PbpA 0.031 ○○○○○ 1.7 1.70449141668119
Escherichia coli M12  CO715_03155  ATI04821.1  831 aa phosphoenolpyruvate--protein phosphotransferase 2.2e-38 ○○○○○ 1.71 1.70577167771316
Escherichia coli M12  CO715_16105  ATI07100.1  288 aa polyamine aminopropyltransferase 0.012 ○○○○○ 1.71 1.70702355379865
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5001  AIK83527.1  424 aa sodium:dicarboxylate symporter family protein <1e-323 ○○○○○ 1.71 1.7074575995474
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4634  AIK83168.1  326 aa high-affinity nickel-transport family protein <1e-323 ○○○○○ 1.71 1.70755763245886
Porphyromonas gingivalis ATCC 33277  PGN_0122  WP_012457262.1  B2RGZ6  291 aa outer membrane lipoprotein Omp28 <1e-323 ○○○○○ 1.71 1.70780097714382
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0110  NP_232511.1  Q9KN55  589 aa hypothetical protein 1.5e-6 ○○○○○ 1.71 1.70817114460917
Mycobacterium avium subsp. paratuberculosis K10  MAP_2601  AAS04918.1  Q73WQ9  357 aa hypothetical protein 0.03 ○○○○○ 1.71 1.70858398036296
Escherichia coli O157:H7 str. EDL933  Z0079  AAG54374.1  552 aa putative transport protein 0.041 ○○○○○ 1.71 1.70902922875551
Mycobacterium avium subsp. paratuberculosis K10  MAP_1244  AAS03561.1  Q740U8  372 aa hypothetical protein 0.03 ○○○○○ 1.71 1.70946315869333
Acinetobacter baumannii ATCC 17978  A1S_0670  ABO11118.1  166 aa protein tyrosine phosphatase 0.0016 ○○○○○ 1.71 1.71006574463548
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1766  CBW17860.1  A0A0H3NHM6  cspC  69 aa cold shock-like protein CspC 5.7e-5 ○○○○○ 1.71 1.71219739373335
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1198  AIK79821.1  419 aa hypothetical protein 0.049 ○○○○○ 1.71 1.71224105080503
Escherichia coli M12  CO715_17935  ATI07432.1  505 aa lysine--tRNA ligase 0.0022 ○○○○○ 1.71 1.71286564219762
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2009  AIK80615.1  180 aa hypothetical protein 1.0e-12 ○○○○○ 1.71 1.71384551895451
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0038  WP_002853081.1  A0A0H3PCH2  rbr  215 aa desulfoferrodoxin FeS4 iron-binding domain-containing protein 0.048 ○○○○○ 1.71 1.71419018855
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4871  AIK83398.1  84 aa 2Fe-2S iron-sulfur cluster binding domain protein <1e-323 ○○○○○ 1.71 1.71429691677821
Escherichia coli M12  CO715_05190  ATI05178.1  218 aa DNA-binding response regulator 6.1e-6 ○○○○○ 1.72 1.71641262443985
Mycobacterium avium subsp. paratuberculosis K10  MAP_2641c  AAS04958.1  Q73WL9  461 aa hypothetical protein 0.03 ○○○○○ 1.72 1.71706230423793
Mycobacterium avium subsp. paratuberculosis K10  MAP_1822c  AAS04139.1  Q73YY1  1020 aa hypothetical protein 0.03 ○○○○○ 1.72 1.71767177259504
Streptococcus pyogenes M1 5448  SP5448_01280  WP_010921882.1  210 aa thiamine diphosphokinase 0.046 ○○○○○ 1.72 1.71773176372277
Mycobacterium avium subsp. paratuberculosis K10  MAP_3968  AAS06518.1  Q73SV5  195 aa hypothetical protein 0.03 ○○○○○ 1.72 1.71850298868108
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1513  WP_009883030.1  Q0Q7I2  439 aa hypothetical protein 0.047 ○○○○○ 1.72 1.71958964381
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0193  WP_002851635.1  A0A0H3PIX0  135 aa membrane protein 0.047 ○○○○○ 1.72 1.7204166219
Mycobacterium avium subsp. paratuberculosis K10  MAP_1068  AAS03385.1  Q741M2  311 aa hypothetical protein 0.03 ○○○○○ 1.72 1.72135333221238
Streptococcus pyogenes M1 5448  SP5448_04695  WP_011285557.1  604 aa glutamine--fructose-6-phosphate transaminase (isomerizing) 0.019 ○○○○○ 1.72 1.72349978271116
Mycobacterium avium subsp. paratuberculosis K10  MAP_1726c  AAS04043.1  Q73Z77  194 aa hypothetical protein 0.03 ○○○○○ 1.72 1.72366375615837
Escherichia coli O157:H7 str. EDL933  Z2239  AAG56297.1  366 aa putative outer membrane porin protein 0.04 ○○○○○ 1.72 1.72402469604966
Mycobacterium avium subsp. paratuberculosis K10  MAP_4314  AAS06864.1  Q73RW4  588 aa hypothetical protein 0.029 ○○○○○ 1.73 1.72563373297193
Porphyromonas gingivalis ATCC 33277  PGN_0421  WP_005873483.1  B2RHU5  234 aa helix-hairpin-helix domain-containing protein 7.2e-8 ○○○○○ 1.73 1.72614001831738
Porphyromonas gingivalis ATCC 33277  PGN_0335  WP_077110981.1  B2RHK9  69 aa hypothetical protein <1e-323 ○○○○○ 1.73 1.72729358559273
Porphyromonas gingivalis ATCC 33277  PGN_0335  WP_012457436.1  B2RHK9  821 aa PKD domain-containing protein <1e-323 ○○○○○ 1.73 1.72729358559273
Mycobacterium avium subsp. paratuberculosis K10  MAP_2373c  AAS04690.1  Q73XD6  346 aa hypothetical protein 0.029 ○○○○○ 1.73 1.72733889596888
Mycobacterium avium subsp. paratuberculosis K10  MAP_0904  AAS03221.1  I3NIF2  246 aa hypothetical protein 0.029 ○○○○○ 1.73 1.72927556032694
Retrieved entries 35,401–35,500 out of 36,363 total in 704.6 ms (Link to these results)