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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4401  AIK82944.1  457 aa cysG <1e-323 ●○○○○ -0.85 -0.852681069347745
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4061  AIK82608.1  82 aa hypothetical protein 0.00091 ●○○○○ -0.85 -0.848932031202139
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4399  AIK82942.1  244 aa phosphoadenosine phosphosulfate reductase <1e-323 ●○○○○ -0.85 -0.845948232871937
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3394  AIK81951.1  500 aa histidine kinase-, DNA gyrase B-, and HSP90-likeATPase family protein 6.5e-14 ●○○○○ -0.85 -0.845600194943583
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4460  AIK83004.1  102 aa toxin SymE, type I toxin-antitoxin system familyprotein 8.8e-13 ●○○○○ -0.84 -0.844846191943587
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3196  AIK81764.1  308 aa bacterial regulatory helix-turn-helix, lysR family protein <1e-323 ●○○○○ -0.84 -0.840733973519043
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3929  AIK82477.1  296 aa 2-hydroxy-3-oxopropionate reductase <1e-323 ●○○○○ -0.84 -0.835873122857
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3237  AIK81798.1  295 aa 5,10-methylenetetrahydrofolate reductase <1e-323 ●○○○○ -0.83 -0.833207001820077
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3437  AIK81994.1  269 aa metQ 1.4e-11 ●○○○○ -0.83 -0.833172178957725
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2679  AIK81273.1  154 aa marR family protein 0.0095 ●○○○○ -0.83 -0.832806808025866
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2232  AIK80837.1  227 aa extensin-like family protein 0.011 ●○○○○ -0.83 -0.829426480666695
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2707  AIK81297.1  420 aa membrane fusion protein of the CusCFBA copper efflux system <1e-323 ●○○○○ -0.83 -0.825607372839241
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3001  AIK81586.1  293 aa bacterial regulatory helix-turn-helix, lysR family protein <1e-323 ●○○○○ -0.82 -0.823289845989549
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4709  AIK83243.1  660 aa glutamate synthase, small subunit domain protein <1e-323 ●○○○○ -0.82 -0.815005777344398
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2281  AIK80886.1  417 aa proA 1.0e-8 ●○○○○ -0.81 -0.812111736320002
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2344  AIK80947.1  301 aa putative DNA-binding transcriptional regulator LYSR-type 0.00011 ●○○○○ -0.81 -0.811647674564552
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4561  AIK83099.1  46 aa hypothetical protein 3.3e-6 ●○○○○ -0.81 -0.809558045017048
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4410  AIK82953.1  253 aa 5'/3'-nucleotidase SurE 9.4e-6 ●○○○○ -0.81 -0.807758251364924
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5004  AIK83530.1  233 aa transcriptional regulatory, C terminal family protein 0.021 ●○○○○ -0.8 -0.804286418281508
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2101  AIK80706.1  57 aa hypothetical protein 3.2e-11 ●○○○○ -0.8 -0.802542888244859
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2454  AIK81051.1  37 aa hypothetical protein 5.2e-9 ●○○○○ -0.8 -0.801170075323225
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5101  AIK83627.1  409 aa esterase family protein 1.7e-11 ●○○○○ -0.8 -0.801112551160483
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4059  AIK82606.1  358 aa hypothetical protein 2.5e-11 ●○○○○ -0.8 -0.801090681601361
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2649  AIK81243.1  146 aa homoprotocatechuate degradation operon regulator, HpaR <1e-323 ●○○○○ -0.8 -0.798529325637838
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4955  AIK83481.1  305 aa substrate binding domain of ABC-type glycine betaine transport system family protein <1e-323 ●○○○○ -0.8 -0.798056558561303
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1923  AIK80529.1  283 aa isochorismatase 1.4e-10 ●○○○○ -0.79 -0.793318070922716
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3381  AIK81938.1  115 aa hypothetical protein 4.0e-12 ●○○○○ -0.79 -0.79242624750557
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3292  AIK81853.1  199 aa &alpha-D-glucose-1-phosphatase <1e-323 ●○○○○ -0.79 -0.791849074639035
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3416  AIK81973.1  246 aa glcNAc-PI de-N-acetylase family protein <1e-323 ●○○○○ -0.79 -0.790443706000435
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4216  AIK82761.1  430 aa arsB <1e-323 ●○○○○ -0.79 -0.789582495421628
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2982  AIK81567.1  305 aa hypothetical protein <1e-323 ●○○○○ -0.79 -0.789342512293834
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3264  AIK81825.1  488 aa rhamnulokinase <1e-323 ●○○○○ -0.79 -0.788709195666586
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3241  AIK81803.1  810 aa metL <1e-323 ●○○○○ -0.79 -0.788261631811689
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4382  AIK82925.1  450 aa D-galactonate transporter family protein <1e-323 ●○○○○ -0.79 -0.785314810018531
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3450  AIK82006.1  240 aa helix-turn-helix domain, rpiR family protein <1e-323 ●○○○○ -0.78 -0.781673046644265
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2690  AIK81284.1  464 aa diguanylate cyclase domain protein 0.039 ●○○○○ -0.78 -0.776459282054829
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3849  AIK82399.1  212 aa stringent starvation protein A 1.5e-5 ●○○○○ -0.78 -0.776035579069185
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3937  AIK82485.1  122 aa hypothetical protein 0.0023 ●○○○○ -0.77 -0.76947128883559
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2514  AIK81111.1  231 aa L-ribulose-5-phosphate 4-epimerase <1e-323 ●○○○○ -0.77 -0.768356799366022
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3395  AIK81952.1  442 aa uhpC <1e-323 ●○○○○ -0.77 -0.76695104216466
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2116  AIK80721.1  356 aa lacI transcriptional repressor 8.0e-8 ●○○○○ -0.76 -0.764915124667677
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2916  AIK81503.1  100 aa small Multidrug Resistance family protein 5.2e-7 ●○○○○ -0.76 -0.764720448065452
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1366  AIK79989.1  477 aa ptsG 6.7e-16 ●○○○○ -0.76 -0.76450715125431
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2325  AIK80929.1  264 aa ubiquinone oxidoreductase, Na(+)-translocating, C subunit <1e-323 ●○○○○ -0.76 -0.762879351883404
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2342  AIK80945.1  258 aa endonuclease/Exonuclease/phosphatase family protein 3.0e-15 ●○○○○ -0.76 -0.760755068043329
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2323  AIK80927.1  198 aa ubiquinone oxidoreductase, Na(+)-translocating, E subunit 3.3e-16 ●○○○○ -0.76 -0.758514946941891
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3255  AIK81816.1  300 aa yiiP <1e-323 ●○○○○ -0.75 -0.753430480767829
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3377  AIK81935.1  240 aa putative transcriptional regulator <1e-323 ●○○○○ -0.75 -0.753124851386771
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4478  AIK83021.1  326 aa PTS system, glucitol/sorbitol-specific, IIBC component family protein 2.3e-7 ●○○○○ -0.75 -0.752052161097731
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2855  AIK81445.1  231 aa 3'(2'),5'-bisphosphate nucleotidase <1e-323 ●○○○○ -0.75 -0.751651418298945
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1577  AIK80197.1  57 aa hypothetical protein 0.00069 ●○○○○ -0.75 -0.750770141489634
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4398  AIK82941.1  570 aa sulfite reductase (NADPH) hemoprotein, beta-component 2.6e-15 ●○○○○ -0.75 -0.749786560239249
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4194  AIK82739.1  572 aa urease, alpha subunit <1e-323 ●○○○○ -0.75 -0.746208210433264
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4016  AIK82563.1  945 aa glnD PII-uridylyltransferase family protein <1e-323 ●○○○○ -0.75 -0.745706301582673
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2612  AIK81206.1  415 aa PTS system, lactose/cellobiose IIC component family protein <1e-323 ●○○○○ -0.75 -0.745429756493662
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4258  AIK82803.1  253 aa 2-deoxy-D-gluconate 3-dehydrogenase 0.0027 ●○○○○ -0.74 -0.744416796233088
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3965  AIK82513.1  295 aa deoC/LacD aldolase family protein <1e-323 ●○○○○ -0.74 -0.741027498627017
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2262  AIK80867.1  224 aa gram-negative pili assembly chaperone, N-terminal domain protein 1.1e-14 ●○○○○ -0.74 -0.739118251601388
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3353  AIK81910.1  191 aa putative phosphopantetheinyl transferase 9.9e-9 ●○○○○ -0.73 -0.734737459222378
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3403  AIK81960.1  239 aa transcriptional regulator protein <1e-323 ●○○○○ -0.73 -0.727821743722681
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2280  AIK80885.1  367 aa proB 2.7e-12 ●○○○○ -0.73 -0.725213715797225
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2705  AIK81295.1  461 aa outer membrane factor of the CusCFBA copper/silver efflux system <1e-323 ●○○○○ -0.72 -0.718990923614531
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1994  AIK80600.1  288 aa helix-turn-helix domain protein 1.7e-9 ●○○○○ -0.72 -0.717838676658245
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1296  AIK79919.1  51 aa hypothetical protein 0.0061 ●○○○○ -0.72 -0.717661394004669
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2859  AIK81448.1  282 aa NAD(P)H:quinone oxidoreductase <1e-323 ●○○○○ -0.72 -0.71507046022692
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4000  AIK82547.1  205 aa urease accessory protein UreG <1e-323 ●○○○○ -0.71 -0.712746962657808
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2636  AIK81230.1  453 aa L-galactonate MFS transporter <1e-323 ●○○○○ -0.71 -0.710872179683227
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3294  AIK81855.1  53 aa putative cytoplasmic protein 3.6e-11 ●○○○○ -0.71 -0.710125428055977
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2512  AIK81109.1  569 aa L-ribulokinase <1e-323 ●○○○○ -0.71 -0.708303451899647
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3134  AIK81706.1  443 aa proline dipeptidase <1e-323 ●○○○○ -0.71 -0.706962082065097
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3365  AIK81922.1  377 aa surface antigen family protein <1e-323 ●○○○○ -0.71 -0.706585300608322
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3675  AIK82230.1  431 aa glucose-1-phosphate adenylyltransferase <1e-323 ●○○○○ -0.7 -0.700627676114841
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2416  AIK81013.1  387 aa type II secretion system protein L 0.0084 ●○○○○ -0.7 -0.699078881271273
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4245  AIK82790.1  279 aa fimbrial family protein 2.2e-16 ●○○○○ -0.7 -0.698295945401244
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2569  AIK81166.1  125 aa hypothetical protein 2.4e-7 ●○○○○ -0.7 -0.697394188039189
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4211  AIK82756.1  102 aa hypothetical protein <1e-323 ●○○○○ -0.7 -0.697197907420795
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3006  AIK81592.1  518 aa EAL domain protein <1e-323 ●○○○○ -0.7 -0.696739233290868
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5046  AIK83572.1  274 aa putative epimerase, with NAD(P)-binding Rossmann-fold domain 0.00035 ●○○○○ -0.7 -0.696182364699856
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4278  AIK82822.1  159 aa acetyltransferase family protein 2.2e-8 ●○○○○ -0.7 -0.695181894687063
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4848  AIK83375.1  509 aa NADH:ubiquinone oxidoreductase, membrane subunitM 0.00033 ●○○○○ -0.69 -0.692205452452173
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3316  AIK81873.1  309 aa ribokinase 0.00065 ●○○○○ -0.69 -0.691320727464093
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2880  AIK81468.1  251 aa ulaR transcriptional repressor 0.0043 ●○○○○ -0.69 -0.69047602886689
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4651  AIK83185.1  771 aa penicillin-binding protein 1C <1e-323 ●○○○○ -0.69 -0.690223275108588
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4333  AIK82878.1  351 aa cobalamin synthesis G family protein 2.6e-9 ●○○○○ -0.69 -0.688831101893836
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4803  AIK83330.1  378 aa D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain protein 1.6e-12 ●○○○○ -0.69 -0.688568961422727
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2431  AIK81028.1  146 aa PTS system fructose IIA component family protein 5.3e-11 ●○○○○ -0.69 -0.686538257660256
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3966  AIK82514.1  98 aa autoinducer 2-degrading protein 2.5e-13 ●○○○○ -0.69 -0.685831521284116
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2851  AIK81440.1  410 aa lacY lactose MFS transporter 9.0e-8 ●○○○○ -0.68 -0.682905434139243
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5134  AIK83658.1  540 aa alpha/beta hydrolase family protein <1e-323 ●○○○○ -0.68 -0.682394584447884
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3304  AIK81865.1  328 aa serine/threonine protein kinase <1e-323 ●○○○○ -0.68 -0.68113966814219
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5153  AIK83674.1  261 aa hypothetical protein <1e-323 ●○○○○ -0.68 -0.680542789780171
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3803  AIK82353.1  379 aa acrA Membrane Fusion Protein <1e-323 ●○○○○ -0.68 -0.680193310601774
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3252  AIK81813.1  306 aa 1,4-dihydroxy-2-naphthoate octaprenyltransferase <1e-323 ●○○○○ -0.68 -0.679693174879263
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2251  AIK80856.1  378 aa receptor ligand binding region family protein 5.5e-14 ●○○○○ -0.68 -0.678703073242904
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3512  AIK82068.1  315 aa divergent polysaccharide deacetylase family protein <1e-323 ●○○○○ -0.68 -0.678624833629621
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3385  AIK81942.1  445 aa dsdX Gnt transporter <1e-323 ●○○○○ -0.68 -0.678281707160214
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4240  AIK82785.1  298 aa triose-phosphate Transporter family protein 1.1e-16 ●○○○○ -0.68 -0.675806271525824
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4057  AIK82604.1  40 aa hypothetical protein 4.4e-9 ●○○○○ -0.68 -0.67510321712607
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2173  AIK80778.1  392 aa oxidoreductase, Gfo/Idh/MocA family 7.6e-11 ●○○○○ -0.67 -0.67175861231512
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2643  AIK81237.1  130 aa hypothetical protein 4.8e-13 ●○○○○ -0.67 -0.670461131413387
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