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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3935  AIK82483.1  233 aa pirin family protein 2.4e-13 ●○○○○ -0.56 -0.562982461218512
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4334  AIK82879.1  241 aa precorrin-3B C17-methyltransferase 5.0e-5 ●○○○○ -0.56 -0.561502616233186
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3318  AIK81875.1  321 aa branched-chain amino acid transport system / permease component family protein 5.0e-14 ●○○○○ -0.56 -0.559320593626867
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2803  AIK81392.1  521 aa amidohydrolase family protein <1e-323 ●○○○○ -0.56 -0.559124810353981
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4024  AIK82571.1  223 aa hypothetical protein 5.4e-5 ●○○○○ -0.56 -0.555618676631425
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4755  AIK83290.1  332 aa sodium Bile acid symporter family protein 8.9e-8 ●○○○○ -0.55 -0.552973300827992
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3484  AIK82040.1  364 aa ABC-2 type transporter family protein <1e-323 ●○○○○ -0.55 -0.552934297249716
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1170  AIK79793.1  249 aa DNA-binding transcriptional regulator 2.7e-5 ●○○○○ -0.55 -0.551785271298602
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3808  AIK82358.1  293 aa ribosomal protein L11 methyltransferase 1.4e-6 ●○○○○ -0.55 -0.549235617126958
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4082  AIK82628.1  352 aa A/G-specific adenine glycosylase <1e-323 ●○○○○ -0.55 -0.548782286256717
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1982  AIK80588.1  82 aa hypothetical protein 8.7e-6 ●○○○○ -0.55 -0.548446574350473
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1651  AIK80271.1  270 aa HAD hydrolase, IIB family protein <1e-323 ●○○○○ -0.55 -0.547764103970216
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3947  AIK82495.1  433 aa exuT hexuronate MFS transporter <1e-323 ●○○○○ -0.55 -0.54737590414674
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1557  AIK80177.1  277 aa dimethyl sulfoxide reductase, chain C 0.0072 ●○○○○ -0.55 -0.546979687003353
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4297  AIK82842.1  614 aa exodeoxyribonuclease V, alpha subunit 0.0017 ●○○○○ -0.55 -0.546267250324507
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3228  AIK81789.1  257 aa acetylglutamate kinase 0.0032 ●○○○○ -0.55 -0.546176668934696
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4577  AIK83115.1  356 aa 3-deoxy-7-phosphoheptulonate synthase 2.4e-13 ●○○○○ -0.54 -0.543988931340732
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3087  AIK81669.1  443 aa response regulator 1.1e-16 ●○○○○ -0.54 -0.543924648033098
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3439  AIK81995.1  284 aa eamA-like transporter family protein 1.5e-7 ●○○○○ -0.54 -0.543368289474342
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1895  AIK80501.1  334 aa branched-chain amino acid transport system / permease component family protein 3.3e-7 ●○○○○ -0.54 -0.541939573576496
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4252  AIK82797.1  153 aa bacterial Transmembrane Pair family protein 3.8e-14 ●○○○○ -0.54 -0.541754880198113
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4264  AIK82809.1  447 aa maltoporin periplasmic N-terminal extension family protein 1.1e-7 ●○○○○ -0.54 -0.539742040849491
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4539  AIK83077.1  282 aa bacterial extracellular solute-binding, 3 familyprotein 0.00016 ●○○○○ -0.54 -0.537501396047818
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1611  AIK80231.1  561 aa aspT/YidE/YbjL antiporter duplication domain protein 4.0e-6 ●○○○○ -0.53 -0.534439942448454
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2277  AIK80882.1  188 aa nlpC/P60 family protein 0.036 ●○○○○ -0.53 -0.534174547745022
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3911  AIK82459.1  335 aa luciferase oxidoreductase, group 1 family protein <1e-323 ●○○○○ -0.53 -0.534039704108892
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3270  AIK81831.1  334 aa branched-chain amino acid transport system / permease component family protein 2.4e-14 ●○○○○ -0.53 -0.533958943286063
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1817  AIK80430.1  895 aa kdpD, KdpD-Phis 6.9e-6 ●○○○○ -0.53 -0.533388455726107
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5158  AIK83679.1  327 aa bacterial regulatory, gntR family protein 0.012 ●○○○○ -0.53 -0.533089918877519
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4863  AIK83390.1  401 aa L-rhamnonate dehydratase <1e-323 ●○○○○ -0.53 -0.53261000472827
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2711  AIK81301.1  242 aa merR regulatory family protein 2.7e-7 ●○○○○ -0.53 -0.531003783290917
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4182  AIK82727.1  440 aa sel1 repeat family protein <1e-323 ●○○○○ -0.53 -0.530126822220152
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4274  AIK82819.1  445 aa PTS system, lactose/cellobiose IIC component family protein <1e-323 ●○○○○ -0.53 -0.528927607205362
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3566  AIK82122.1  452 aa ankyrin repeat family protein <1e-323 ●○○○○ -0.53 -0.528195385862833
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4325  AIK82870.1  303 aa bacterial regulatory helix-turn-helix, AraC family protein 6.0e-5 ●○○○○ -0.53 -0.527487064330294
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4597  AIK83131.1  361 aa RNA 2'-O ribose methyltransferase substrate binding family protein 0.011 ●○○○○ -0.53 -0.527401802694058
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3653  AIK82208.1  255 aa ABC transporter family protein 0.0028 ●○○○○ -0.53 -0.52725524636805
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2172  AIK80777.1  454 aa sugar (and other) transporter family protein 2.4e-12 ●○○○○ -0.53 -0.526547383806416
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4307  AIK82852.1  408 aa rnfC Barrel sandwich hybrid domain protein 4.5e-5 ●○○○○ -0.53 -0.526388597262079
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3272  AIK81833.1  104 aa L-rhamnose 1-epimerase <1e-323 ●○○○○ -0.52 -0.523822438973835
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2005  AIK80611.1  494 aa feaB 1.6e-7 ●○○○○ -0.52 -0.522708215068277
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3660  AIK82215.1  356 aa ugpC 9.4e-11 ●○○○○ -0.52 -0.521368481852737
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4653  AIK83187.1  388 aa 23S rRNA m2A2503 methyltransferase 6.4e-9 ●○○○○ -0.52 -0.519588098582954
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2331  AIK80935.1  814 aa acyl-CoA dehydrogenase, C-terminal domain protein <1e-323 ●○○○○ -0.52 -0.519382793706572
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2113  AIK80719.1  47 aa ribosomal protein L36 3.7e-10 ●○○○○ -0.52 -0.516706386803599
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2419  AIK81016.1  266 aa type 4 prepilin-like proteins leader peptide-processing enzyme 9.6e-10 ●○○○○ -0.52 -0.516435184168627
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4530  AIK83068.1  173 aa fimbrial family protein 1.0e-6 ●○○○○ -0.51 -0.514675295416936
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3275  AIK81836.1  331 aa HTH-type transcriptional regulator rafR <1e-323 ●○○○○ -0.51 -0.513756147189022
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3338  AIK81895.1  55 aa hypothetical protein <1e-323 ●○○○○ -0.51 -0.513748536740732
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4518  AIK83056.1  132 aa putative inner membrane protein 2.1e-12 ●○○○○ -0.51 -0.513074384582407
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3003  AIK81588.1  449 aa permease family protein 1.8e-7 ●○○○○ -0.51 -0.512872894759008
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2493  AIK81090.1  523 aa 2-isopropylmalate synthase <1e-323 ●○○○○ -0.51 -0.509915870118097
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4456  AIK82999.1  569 aa hydrogenase 4, large subunit <1e-323 ●○○○○ -0.51 -0.508331035678011
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3452  AIK82008.1  519 aa PTS system, glucose-like IIB component domain protein <1e-323 ●○○○○ -0.51 -0.506902311815675
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4711  AIK83246.1  664 aa transketolase <1e-323 ●○○○○ -0.5 -0.504528077514068
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4648  AIK83182.1  280 aa hypothetical protein <1e-323 ●○○○○ -0.5 -0.50377285911206
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4386  AIK82929.1  916 aa hybrid sensory histidine kinase, in two-component regulatory system with UvrY <1e-323 ●○○○○ -0.5 -0.50351482077411
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4343  AIK82888.1  181 aa cobU 7.6e-6 ●○○○○ -0.5 -0.502932242896057
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3352  AIK81909.1  188 aa chromate reductase monomer <1e-323 ●○○○○ -0.5 -0.499454750372802
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2927  AIK81513.1  856 aa type VII secretion system (T7SS), usher family protein 2.9e-13 ●○○○○ -0.5 -0.498586444419418
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4404  AIK82947.1  201 aa adenylylsulfate kinase 2.2e-16 ●○○○○ -0.5 -0.496210823913605
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3583  AIK82138.1  517 aa cellulose biosynthesis protein BcsE 1.6e-7 ●○○○○ -0.5 -0.495079571485446
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2949  AIK81534.1  671 aa poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB 1.1e-8 ●○○○○ -0.49 -0.494553214921837
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2780  AIK81369.1  622 aa pfkB carbohydrate kinase family protein <1e-323 ●○○○○ -0.49 -0.494205000938142
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3824  AIK82374.1  481 aa modulator of DNA gyrase family protein <1e-323 ●○○○○ -0.49 -0.494187176347172
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2886  AIK81475.1  141 aa nsrR 1.0e-12 ●○○○○ -0.49 -0.493950775822928
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4149  AIK82695.1  203 aa DSBA-like thioredoxin domain protein 5.7e-15 ●○○○○ -0.49 -0.492501726694177
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4218  AIK82763.1  517 aa H+ symporter family protein 5.8e-14 ●○○○○ -0.49 -0.491404734946161
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3468  AIK82024.1  693 aa ATP-dependent DNA helicase RecG 5.5e-15 ●○○○○ -0.49 -0.491382215309642
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3627  AIK82182.1  551 aa 4-amino-4-deoxy-L-arabinose (L-Ara4N) transferase <1e-323 ●○○○○ -0.49 -0.491049673586487
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2227  AIK80832.1  269 aa pyrroline-5-carboxylate reductase 3.7e-6 ●○○○○ -0.49 -0.48772292507304
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2825  AIK81414.1  372 aa cys/Met metabolism PLP-dependent enzyme family protein <1e-323 ●○○○○ -0.49 -0.485986840579237
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4271  AIK82815.1  237 aa putative aspartate/glutamate racemase 5.6e-16 ●○○○○ -0.48 -0.483147367786938
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3717  AIK82272.1  108 aa nitrite reductase [NAD(P)H] small subunit 7.2e-7 ●○○○○ -0.48 -0.482817411821624
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4942  AIK83468.1  303 aa tRNA dihydrouridine synthase 0.00018 ●○○○○ -0.48 -0.482813081392585
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3010  AIK81595.1  285 aa binding-protein-dependent transport system innermembrane component family protein <1e-323 ●○○○○ -0.48 -0.47963102483037
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1603  AIK80223.1  377 aa potG 2.6e-14 ●○○○○ -0.48 -0.479611394771636
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1268  AIK79891.1  427 aa hypothetical protein 3.3e-16 ●○○○○ -0.48 -0.479362639013665
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3478  AIK82034.1  287 aa hypothetical protein 0.0038 ●○○○○ -0.48 -0.479325526577835
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3715  AIK82270.1  334 aa tryptophan--tRNA ligase 2.7e-5 ●○○○○ -0.48 -0.478491563799681
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4204  AIK82749.1  137 aa crcB-like family protein 8.4e-8 ●○○○○ -0.47 -0.473740798391913
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3725  AIK82280.1  189 aa cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD family protein 2.3e-8 ●○○○○ -0.47 -0.472919359349462
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1931  AIK80537.1  1293 aa amino acid adenylation domain protein 0.00016 ●○○○○ -0.47 -0.472665772170851
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3815  AIK82365.1  333 aa sulfoxide reductase catalytic subunit yedY 0.016 ●○○○○ -0.47 -0.472358346823231
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3572  AIK82127.1  337 aa dppF 1.1e-16 ●○○○○ -0.47 -0.471634174907357
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4857  AIK83384.1  458 aa O-succinylbenzoate-CoA ligase 0.0022 ●○○○○ -0.47 -0.470925063634301
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3698  AIK82253.1  540 aa phosphoenolpyruvate carboxykinase <1e-323 ●○○○○ -0.47 -0.470335923290608
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3953  AIK82501.1  329 aa oxidoreductase, NAD-binding Rossmann fold family protein <1e-323 ●○○○○ -0.46 -0.462649045825629
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3615  AIK82170.1  132 aa nickel-responsive transcriptional regulator NikR <1e-323 ●○○○○ -0.46 -0.462346607518332
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2798  AIK81387.1  254 aa tRNA- family protein 0.00045 ●○○○○ -0.46 -0.461694972158763
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1619  AIK80239.1  394 aa baseplate J-like family protein <1e-323 ●○○○○ -0.46 -0.460189104149127
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3094  AIK81675.1  223 aa endonuclease V 7.0e-10 ●○○○○ -0.46 -0.459953888346532
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4034  AIK82581.1  219 aa qseB transcriptional activator 2.2e-12 ●○○○○ -0.46 -0.45965435921475
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4914  AIK83440.1  234 aa protein with low undecaprenyl pyrophosphate phosphatase activity 0.015 ●○○○○ -0.46 -0.459460735208506
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4602  AIK83135.1  245 aa putative S-adenosyl-L-methionine-dependent methyltransferase 1.7e-5 ●○○○○ -0.46 -0.45721137507179
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4276  AIK82821.1  257 aa uxuR transcriptional repressor 0.0007 ●○○○○ -0.46 -0.45670843275178
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3667  AIK82222.1  231 aa pirin-like protein <1e-323 ●○○○○ -0.46 -0.456598062404465
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4448  AIK82991.1  373 aa hydrogenase expression/formation protein HypD <1e-323 ●○○○○ -0.46 -0.455262027819293
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3701  AIK82256.1  227 aa HAD hydrolase, IA, variant 3 family protein 6.5e-10 ●○○○○ -0.45 -0.454803535329265
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3540  AIK82096.1  440 aa xylose isomerase <1e-323 ●○○○○ -0.45 -0.453038147248505
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