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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4298  WP_000149714.1  E8XL70  pflD  765 aa formate C-acetyltransferase n.s. ●○○○○ -0.21 -0.213385735705555
Vibrio parahaemolyticus RIMD 2210633  VPA_1135  BAC62478.1  Q87H30  182 aa putative acetyltransferase n.s. ●○○○○ -0.21 -0.213244762906111
Mycobacterium avium subsp. paratuberculosis K10  MAP_2668c  AAS04985.1  Q73WJ2  157 aa hypothetical protein n.s. ●○○○○ -0.21 -0.21311878517473
Streptococcus pyogenes M1 5448  SP5448_01275  WP_002992061.1  220 aa ribulose-phosphate 3-epimerase n.s. ●○○○○ -0.21 -0.212824191690959
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3142  CBW19241.1  A0A0H3NM16  ygiR  723 aa conserved hypothetical protein n.s. ●○○○○ -0.21 -0.212592135855302
Serratia marcescens Strain UMH9  BVG96_07505  ASL97467.1  97 aa peptidase inhibitor I78 family protein n.s. ●○○○○ -0.21 -0.212586514196636
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0368  WP_002854718.1  A0A0H3PEL9  41 aa hypothetical protein n.s. ●○○○○ -0.21 -0.212492977735
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2570  WP_000997656.1  E8XFS6  eutT  267 aa ethanolamine utilization cob(I)yrinic acid a,c-diamide adenosyltransferase EutT n.s. ●○○○○ -0.21 -0.212484961469681
Streptococcus pyogenes M1 5448  SP5448_05930  WP_002984894.1  309 aa ribonuclease Z n.s. ●○○○○ -0.21 -0.21224738979212
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0591  WP_011812720.1  Q0Q7L4  288 aa hypothetical protein n.s. ●○○○○ -0.21 -0.212170298145
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4462  WP_000958575.1  E8X9R7  222 aa glutathione S-transferase n.s. ●○○○○ -0.21 -0.212110379760405
Streptococcus pyogenes M1 5448  SP5448_03480  WP_020837421.1  31 aa type I toxin-antitoxin system Fst family toxin n.s. ●○○○○ -0.21 -0.211766721543087
Streptococcus pyogenes M1 5448  SP5448_03480  WP_011285631.1  115 aa helix-turn-helix transcriptional regulator n.s. ●○○○○ -0.21 -0.211766721543087
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0392  CBW16492.1  A0A0H3NDH6  phoB  229 aa phosphate regulon transcriptional regulatory protein PhoB n.s. ●○○○○ -0.21 -0.211648413294165
Mycobacterium avium subsp. paratuberculosis K10  MAP_0518  AAS02835.1  Q743S3  301 aa hypothetical protein n.s. ●○○○○ -0.21 -0.211585077311089
Escherichia coli CFT073  c2962  AAN81412.1  Q8FFA9  murP  474 aa Putative PTS system IIBC component yfeV n.s. ●○○○○ -0.21 -0.211560585659436
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3639  WP_000920478.1  E8XEH5  ppia  190 aa peptidylprolyl isomerase A n.s. ●○○○○ -0.21 -0.211419019186344
Escherichia coli O157:H7 str. EDL933  Z5042  AAG58762.1  338 aa putative regulator n.s. ●○○○○ -0.21 -0.21130537715172
Acinetobacter baumannii ATCC 17978  A1S_2910  ABO13315.2  A3M8S1  queA  345 aa S-adenosylmethionine:tRNA ribosyltransferase-isomerase n.s. ●○○○○ -0.21 -0.211156088495991
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1213  WP_001114323.1  E8XFE3  mfd  1148 aa transcription-repair coupling factor n.s. ●○○○○ -0.21 -0.211059084229498
Mycobacterium avium subsp. paratuberculosis K10  MAP_1687  AAS04004.1  Q73ZB6  817 aa hypothetical protein n.s. ●○○○○ -0.21 -0.211023454006363
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4025  CBW20114.1  A0A0H3NI78  ydeZ  333 aa hypothetical ABC transporter, membrane component n.s. ●○○○○ -0.21 -0.210910484331797
Mycobacterium avium subsp. paratuberculosis K10  MAP_0447  AAS02764.1  Q743Z4  137 aa hypothetical protein n.s. ●○○○○ -0.21 -0.210676267153519
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0180  WP_009881803.1  A0A0H3PEF7  659 aa methyl-accepting chemotaxis protein n.s. ●○○○○ -0.21 -0.21062125129
Acinetobacter baumannii ATCC 17978  A1S_0403  ABO10860.2  1110 aa ribonuclease E n.s. ●○○○○ -0.21 -0.210549372692173
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1607  AIK80227.1  240 aa NADPH-flavin oxidoreductase n.s. ●○○○○ -0.21 -0.210505093617224
Haemophilus influenzae Rd KW20  HI_0714  NP_438872.3  P43867  clpP  193 aa ATP-dependent Clp protease proteolytic subunit n.s. ●○○○○ -0.21 -0.210492362823782
Haemophilus influenzae Rd KW20  HI_0527  NP_438685.1  P44746  86 aa ferredoxin n.s. ●○○○○ -0.21 -0.210492362823782
Serratia marcescens Strain UMH9  BVG96_08485  ASL97649.1  697 aa GGDEF domain-containing protein n.s. ●○○○○ -0.21 -0.210469790298639
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3698  WP_000078494.1  E8XEN4  571 aa dihydroxy-acid dehydratase n.s. ●○○○○ -0.21 -0.210313885259536
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1529  CBW17623.1  A0A0H3NLF4  ydcR  474 aa hypothetical regulatory protein n.s. ●○○○○ -0.21 -0.210192055139581
Mycobacterium avium subsp. paratuberculosis K10  MAP_1218c  AAS03535.1  Q740X4  97 aa hypothetical protein n.s. ●○○○○ -0.21 -0.210104935503279
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0351  NP_232747.1  Q9KMJ5  198 aa hypothetical protein n.s. ●○○○○ -0.21 -0.209991333320767
Acinetobacter baumannii ATCC 17978  A1S_2395  ABO12814.2  228 aa hypothetical protein n.s. ●○○○○ -0.21 -0.209895967292608
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0724  WP_000186054.1  E8XA55  kdpE  225 aa two-component system response regulator KdpE n.s. ●○○○○ -0.21 -0.209877400716033
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4345  WP_000847565.1  E8XLA5  thiH  377 aa 2-iminoacetate synthase ThiH n.s. ●○○○○ -0.21 -0.209790231143302
Streptococcus pyogenes M1 5448  SP5448_06785  WP_010922104.1  650 aa DNA gyrase subunit B n.s. ●○○○○ -0.21 -0.209651781247345
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3922  WP_000766669.1  E8XGU8  yicH  569 aa AsmA family protein n.s. ●○○○○ -0.21 -0.209562825822931
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0345  NP_232741.1  Q9KMJ8  209 aa hypothetical protein n.s. ●○○○○ -0.21 -0.209514842240867
Mycobacterium avium subsp. paratuberculosis K10  MAP_3815  AAS06365.1  Q73TA3  284 aa hypothetical protein n.s. ●○○○○ -0.21 -0.20923823682342
Escherichia coli O157:H7 str. EDL933  Z4919  AAG58648.1  256 aa putative ATP-binding protein of ABC transport system n.s. ●○○○○ -0.21 -0.209203671185808
Serratia marcescens Strain UMH9  BVG96_14195  ASL98704.1  469 aa amino acid permease n.s. ●○○○○ -0.21 -0.209029748366316
Acinetobacter baumannii ATCC 17978  A1S_2141  ABO12568.1  194 aa potassium-transporting ATPase A chain n.s. ●○○○○ -0.21 -0.208977374732637
Mycobacterium avium subsp. paratuberculosis K10  MAP_1533  AAS03850.1  Q73ZR8  335 aa hypothetical protein n.s. ●○○○○ -0.21 -0.208854339135759
Serratia marcescens Strain UMH9  BVG96_19930  ASL99748.1  203 aa transcriptional regulator n.s. ●○○○○ -0.21 -0.208762373292202
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0083  CBW16184.1  A0A0H3N8Y3  96 aa probable secreted protein n.s. ●○○○○ -0.21 -0.208740206264835
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3897  CBW19987.1  A0A0H3NHV8  120 aa conserved hypothetical protein n.s. ●○○○○ -0.21 -0.208663739764859
Vibrio parahaemolyticus RIMD 2210633  VP_1295  BAC59558.1  Q87Q55  257 aa hypothetical protein n.s. ●○○○○ -0.21 -0.208631356466175
Mycobacterium avium subsp. paratuberculosis K10  MAP_0306c  AAS02623.1  Q744N5  gshA  436 aa GshA n.s. ●○○○○ -0.21 -0.20856720570781
Serratia marcescens Strain UMH9  BVG96_01560  ASL96369.1  309 aa hypothetical protein n.s. ●○○○○ -0.21 -0.208416053098742
Vibrio parahaemolyticus RIMD 2210633  VP_1756  BAC60019.1  Q87NW2  159 aa hypothetical protein n.s. ●○○○○ -0.21 -0.20828192909103
Acinetobacter baumannii ATCC 17978  A1S_3244  ABO13634.2  316 aa putative homoserine kinase (ThrB) n.s. ●○○○○ -0.21 -0.208137412221996
Vibrio parahaemolyticus RIMD 2210633  VP_1375  BAC59638.1  Q87PX5  445 aa sensor histidine kinase n.s. ●○○○○ -0.21 -0.207901560222809
Serratia marcescens Strain UMH9  BVG96_17110  ASL99235.1  252 aa helix-turn-helix domain-containing protein n.s. ●○○○○ -0.21 -0.207849180639075
Mycobacterium avium subsp. paratuberculosis K10  MAP_0814c  AAS03131.1  Q742M1  166 aa hypothetical protein n.s. ●○○○○ -0.21 -0.207788517323796
Vibrio parahaemolyticus RIMD 2210633  VP_2093  BAC60356.1  Q87MY3  85 aa molybdenum cofactor biosynthesis protein D n.s. ●○○○○ -0.21 -0.207746764224849
Mycobacterium avium subsp. paratuberculosis K10  MAP_3804  AAS06354.1  Q73TB4  273 aa hypothetical protein n.s. ●○○○○ -0.21 -0.20762741826185
Serratia marcescens Strain UMH9  BVG96_15740  ASL98990.1  412 aa MFS transporter n.s. ●○○○○ -0.21 -0.207617298846786
Mycobacterium avium subsp. paratuberculosis K10  MAP_3188  AAS05736.1  Q73V28  fadE24  463 aa FadE24 n.s. ●○○○○ -0.21 -0.207560474405015
Acinetobacter baumannii ATCC 17978  A1S_1232  ABO11661.2  148 aa EsvB n.s. ●○○○○ -0.21 -0.20740253570102
Serratia marcescens Strain UMH9  BVG96_15460  ASL98945.1  882 aa protein acetyltransferase n.s. ●○○○○ -0.21 -0.20736706965852
Mycobacterium avium subsp. paratuberculosis K10  MAP_0585  AAS02902.1  Q743K0  341 aa hypothetical protein n.s. ●○○○○ -0.21 -0.207132249178943
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1681  NP_231317.1  Q9KRG1  320 aa peptide ABC transporter permease n.s. ●○○○○ -0.21 -0.20697309711612
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0639  CBW16739.2  A0A0H3NAM7  kdgT  294 aa probable permease n.s. ●○○○○ -0.21 -0.206733982788553
Escherichia coli CFT073  c1203  AAN79665.1  A0A0H2V620  352 aa Putative O-methyltransferase n.s. ●○○○○ -0.21 -0.206698577706568
Serratia marcescens Strain UMH9  BVG96_07775  ASL97518.1  334 aa bile acid:sodium symporter n.s. ●○○○○ -0.21 -0.206649852313949
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0613  CBW16713.1  A0A0H3NIV7  citA  553 aa sensor kinase DpiB n.s. ●○○○○ -0.21 -0.206567179606304
Vibrio parahaemolyticus RIMD 2210633  VPA_1223  BAC62566.1  Q87GU2  216 aa conserved hypothetical protein n.s. ●○○○○ -0.21 -0.206550901145429
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1832  CBW17926.1  A0A0H3NCN5  yebB  199 aa conserved hypothetical protein n.s. ●○○○○ -0.21 -0.206539746275107
Serratia marcescens Strain UMH9  BVG96_02765  ASL96587.1  243 aa hypothetical protein n.s. ●○○○○ -0.21 -0.206527312541072
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1921  CBW18016.1  A0A0H3NI35  yedJ  231 aa conserved hypothetical protein n.s. ●○○○○ -0.21 -0.206487654780126
Serratia marcescens Strain UMH9  BVG96_12470  ASL98389.1  299 aa glyoxalase n.s. ●○○○○ -0.21 -0.206233273443751
Vibrio parahaemolyticus RIMD 2210633  VPA_0486  BAC61829.1  Q87IX0  315 aa hypothetical protein n.s. ●○○○○ -0.21 -0.206231303213828
Streptococcus pyogenes M1 5448  SP5448_08510  WP_011285722.1  1465 aa PolC-type DNA polymerase III n.s. ●○○○○ -0.21 -0.206094836204505
Serratia marcescens Strain UMH9  BVG96_14750  ASL98809.1  277 aa enoyl-CoA hydratase n.s. ●○○○○ -0.21 -0.206062135025797
Mycobacterium avium subsp. paratuberculosis K10  MAP_3027  AAS05575.1  Q73VI6  233 aa hypothetical protein n.s. ●○○○○ -0.21 -0.206045404395153
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0734  CBW16832.1  A0A0H3NAV6  pnuC  239 aa pnuC protein n.s. ●○○○○ -0.21 -0.205966302525002
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1388  WP_002855628.1  A0A0H3PIE9  156 aa Cj1386 family hemin-binding protein n.s. ●○○○○ -0.21 -0.2059335998
Haemophilus influenzae Rd KW20  HI_0570  NP_438727.1  P44757  205 aa DNA-binding transcriptional repressor FabR n.s. ●○○○○ -0.21 -0.205748940479881
Haemophilus influenzae Rd KW20  HI_1147  NP_439305.1  P45072  ptsN  164 aa nitrogen regulatory IIA protein n.s. ●○○○○ -0.21 -0.205748940479881
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4127  CBW20215.1  A0A0H3NKA8  179 aa conserved hypothetical protein n.s. ●○○○○ -0.21 -0.205747524006081
Mycobacterium avium subsp. paratuberculosis K10  MAP_3236  AAS05784.1  Q73UY0  catB  706 aa CatB n.s. ●○○○○ -0.21 -0.20563040170211
Vibrio parahaemolyticus RIMD 2210633  VPA_1413  BAC62756.1  Q87GA4  133 aa hypothetical protein n.s. ●○○○○ -0.21 -0.205444791959514
Serratia marcescens Strain UMH9  BVG96_00715  ASL96218.1  205 aa cell filamentation protein Fic n.s. ●○○○○ -0.21 -0.2054322472649
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2539  WP_000565119.1  E8XFP5  ptsJ  430 aa transcriptional regulator PtsJ n.s. ●○○○○ -0.21 -0.205398182964481
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2908  WP_001221110.1  E8XJD3  iroB  371 aa DUF1205 domain-containing protein n.s. ●○○○○ -0.21 -0.20513106045414
Streptococcus pyogenes M1 5448  SP5448_02405  WP_002983445.1  77 aa hypothetical protein n.s. ●○○○○ -0.21 -0.205037366056634
Mycobacterium avium subsp. paratuberculosis K10  MAP_0009  AAS02326.1  Q744Q5  441 aa hypothetical protein n.s. ●○○○○ -0.21 -0.205009100034388
Mycobacterium avium subsp. paratuberculosis K10  MAP_0242c  AAS02559.1  Q745N1  168 aa hypothetical protein n.s. ●○○○○ -0.2 -0.204866336668586
Serratia marcescens Strain UMH9  BVG96_12515  ASL98398.1  228 aa aspartyl beta-hydroxylase n.s. ●○○○○ -0.2 -0.204771651229031
Mycobacterium avium subsp. paratuberculosis K10  MAP_1479c  AAS03796.1  Q73ZX2  198 aa hypothetical protein n.s. ●○○○○ -0.2 -0.204583567487837
Streptococcus pyogenes M1 5448  SP5448_08040  WP_002990993.1  160 aa transcription elongation factor GreA n.s. ●○○○○ -0.2 -0.204460564157795
Serratia marcescens Strain UMH9  BVG96_02820  ASL96597.1  388 aa succinate--CoA ligase subunit beta n.s. ●○○○○ -0.2 -0.20437327504505
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3778  AIK82333.1  329 aa DNA-directed RNA polymerase, alpha subunit n.s. ●○○○○ -0.2 -0.204332024963965
Serratia marcescens Strain UMH9  BVG96_09050  ASL97753.1  1034 aa multidrug efflux RND transporter permease subunit n.s. ●○○○○ -0.2 -0.204295773722048
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3866  CBW19955.1  A0A0H3NHT6  105 aa conserved hypothetical protein n.s. ●○○○○ -0.2 -0.204245535537355
Streptococcus pyogenes M1 5448  SP5448_06560  WP_002990299.1  120 aa large conductance mechanosensitive channel protein MscL n.s. ●○○○○ -0.2 -0.204172163208375
Mycobacterium avium subsp. paratuberculosis K10  MAP_3975  AAS06525.1  Q73SU8  murB  372 aa MurB n.s. ●○○○○ -0.2 -0.204147519357242
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1158  WP_002869020.1  A0A0H3PAN1  346 aa N-acetylneuraminate synthase n.s. ●○○○○ -0.2 -0.204092442802
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2227  CBW18329.1  A0A0H3NJI2  napH  289 aa ferredoxin-type protein NapH n.s. ●○○○○ -0.2 -0.20401503462989
Retrieved entries 15,601–15,700 out of 36,363 total in 147.1 ms (Link to these results)