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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2221  AIK80826.1  94 aa hypothetical protein 0.0034 ●○○○○ -0.32 -0.321966549907868
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1024  NP_233408.2  Q9KKS6  83 aa hypothetical protein 0.0038 ●○○○○ -0.32 -0.321952170266399
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2276  NP_231907.1  Q9KPT6  415 aa fermentation/respiration switch protein 7.6e-6 ●○○○○ -0.32 -0.321829017643434
Escherichia coli M12  CO715_09340  ATI05896.1  263 aa endonuclease VIII 2.9e-18 ●○○○○ -0.32 -0.321641642743028
Acinetobacter baumannii ATCC 17978  A1S_2994  ABO13395.1  123 aa hypothetical protein 0.031 ●○○○○ -0.32 -0.321174467972283
Porphyromonas gingivalis ATCC 33277  PGN_1782  WP_012458529.1  B2RLQ6  551 aa DNA repair protein RecN 0.0053 ●○○○○ -0.32 -0.321064726920463
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2333  AIK80937.1  151 aa lysE type translocator family protein 9.0e-5 ●○○○○ -0.32 -0.320790763263803
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3135  AIK81707.1  729 aa fatty oxidation complex, alpha subunit FadB 0.0012 ●○○○○ -0.32 -0.320472197742692
Escherichia coli M12  CO715_02540  ATI04710.1  97 aa hypothetical protein 0.00083 ●○○○○ -0.32 -0.319972474629037
Escherichia coli M12  CO715_11330  ATI06243.1  459 aa MFS transporter 5.0e-195 ●○○○○ -0.32 -0.31934653658629
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4032  AIK82579.1  193 aa flavodoxin-like fold family protein 0.00099 ●○○○○ -0.32 -0.319172427268432
Escherichia coli M12  CO715_23035  ATI08348.1  447 aa gluconate transporter 5.1e-6 ●○○○○ -0.32 -0.318303306515046
Escherichia coli M12  CO715_24545  ATI08600.1  133 aa sigma factor-binding protein Crl 0.0017 ●○○○○ -0.32 -0.318303306515046
Porphyromonas gingivalis ATCC 33277  PGN_0288  WP_010955942.1  B2RHG2  mfa2  324 aa hypothetical protein <1e-323 ●○○○○ -0.32 -0.317960107756787
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0088  NP_232489.1  Q9KN77  424 aa proton/glutamate symporter 0.048 ●○○○○ -0.32 -0.317817297801127
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4497  AIK83035.1  518 aa glutamate--cysteine ligase 3.4e-12 ●○○○○ -0.32 -0.317656890499505
Escherichia coli M12  CO715_11250  ATI06228.1  90 aa hypothetical protein 1.3e-14 ●○○○○ -0.32 -0.317260076443802
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2856  AIK81444.1  185 aa hypothetical protein 3.0e-9 ●○○○○ -0.32 -0.317052531834923
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3379  AIK81936.1  540 aa PTS system, alpha-glucoside-specific IIBC component domain protein <1e-323 ●○○○○ -0.32 -0.316865074300291
Escherichia coli M12  CO715_04575  ATI05075.1  216 aa metal-binding protein ZinT 1.5e-5 ●○○○○ -0.32 -0.316425492386806
Porphyromonas gingivalis ATCC 33277  PGN_1633  WP_004584814.1  B2RLA7  300 aa glutamate formimidoyltransferase 0.0042 ●○○○○ -0.32 -0.316013623485079
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2938  AIK81524.1  598 aa fused thiol:disulfide interchange protein: membrane electron transporter: activator of DsbC 2.8e-10 ●○○○○ -0.31 -0.314670386668882
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2653  AIK81247.1  285 aa 3,4-dihydroxyphenylacetate 2,3-dioxygenase <1e-323 ●○○○○ -0.31 -0.314651115582891
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2739  AIK81329.1  1228 aa eco57I restriction-modification methylase familyprotein <1e-323 ●○○○○ -0.31 -0.314606230252921
Escherichia coli M12  CO715_16635  ATI07200.1  227 aa molecular chaperone 0.0011 ●○○○○ -0.31 -0.314547678258566
Escherichia coli M12  CO715_02235  ATI04655.1  434 aa isocitrate lyase 0.0002 ●○○○○ -0.31 -0.31392174021582
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3794  AIK82349.1  50 aa hypothetical protein 9.0e-6 ●○○○○ -0.31 -0.313383547766035
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0881  NP_233267.1  Q9KL66  131 aa motility-associated killing factor operon protein MakC 0.014 ●○○○○ -0.31 -0.31293663425195
Escherichia coli M12  CO715_24775  ATI08638.1  169 aa GTPase-activating protein 0.0051 ●○○○○ -0.31 -0.312461218116078
Escherichia coli M12  CO715_04935  ATI05135.1  291 aa ISAs1 family transposase 0.0025 ●○○○○ -0.31 -0.312252572101829
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3645  AIK82200.1  421 aa 4-aminobutyrate transaminase 1.2e-9 ●○○○○ -0.31 -0.311603291885969
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2646  AIK81240.1  338 aa dpkA 1.1e-12 ●○○○○ -0.31 -0.311270380974611
Porphyromonas gingivalis ATCC 33277  PGN_0070  WP_012457215.1  B2RGU4  196 aa hypothetical protein <1e-323 ●○○○○ -0.31 -0.309960313819574
Escherichia coli M12  CO715_13665  ATI06661.1  138 aa regulator of ribonuclease activity B 0.033 ●○○○○ -0.31 -0.309957465945091
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2960  AIK81545.1  471 aa sugar (Glycoside-Pentoside-Hexuronide) transporter domain protein <1e-323 ●○○○○ -0.31 -0.309803170225929
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0377  NP_230031.1  Q9KUY1  153 aa hypothetical protein 5.4e-6 ●○○○○ -0.31 -0.30860171323884
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0726  NP_233113.1  Q9KLL7  254 aa molybdenum ABC transporter substrate-binding protein 0.0027 ●○○○○ -0.31 -0.30849909866587
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2836  AIK81425.1  402 aa putative thioredoxin-like protein 1.4e-10 ●○○○○ -0.31 -0.308412411231488
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1518  NP_231158.1  Q9KRW6  158 aa hypothetical protein 0.00011 ●○○○○ -0.31 -0.3083297284999
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4145  AIK82691.1  247 aa putative NAD(P)-binding oxidoreductase with NAD(P)-binding Rossmann-fold domain 1.7e-12 ●○○○○ -0.31 -0.30802263902877
Acinetobacter baumannii ATCC 17978  A1S_1995  ABO12422.2  411 aa molybdopterin biosynthesis protein 0.027 ●○○○○ -0.31 -0.307523007482565
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2017  NP_231651.1  Q9KQI1  mltG  338 aa hypothetical protein 0.013 ●○○○○ -0.31 -0.307390350691689
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4101  AIK82647.1  232 aa extracellular deoxyribonuclease 4.8e-13 ●○○○○ -0.31 -0.307277148642546
Escherichia coli M12  CO715_15100  ATI06925.1  380 aa NADH:flavin oxidoreductase 3.5e-19 ●○○○○ -0.31 -0.307036421745608
Acinetobacter baumannii ATCC 17978  A1S_2453  ABO12871.2  510 aa L-24-diaminobutyrate decarboxylase 0.045 ●○○○○ -0.31 -0.306862982592971
Escherichia coli M12  CO715_08870  ATI05816.1  253 aa EEP domain-containing protein 5.6e-11 ●○○○○ -0.31 -0.305367253631617
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0840  NP_230488.1  Q9KTQ7  626 aa accessory colonization factor AcfB 4.0e-5 ●○○○○ -0.3 -0.304960819089919
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2291  NP_231922.1  Q9X4Q7  nqrE  198 aa Na(+)-translocating NADH-quinone reductase subunit E 0.028 ●○○○○ -0.3 -0.3049068997442
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1832  AIK80445.1  266 aa glucosamine-6-phosphate deaminase 0.0005 ●○○○○ -0.3 -0.304382629232573
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3648  AIK82203.1  127 aa hypothetical protein 8.4e-12 ●○○○○ -0.3 -0.303592395365093
Escherichia coli M12  CO715_16550  ATI07184.1  196 aa carnitine operon protein CaiE 0.0064 ●○○○○ -0.3 -0.303280793489128
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0125  NP_229783.1  Q9KVL7  lysA  417 aa diaminopimelate decarboxylase 0.00047 ●○○○○ -0.3 -0.303112232780835
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4042  AIK82589.1  275 aa 2,5-diketo-D-gluconic acid reductase A 0.00087 ●○○○○ -0.3 -0.30277276417837
Acinetobacter baumannii ATCC 17978  A1S_3337  ABO13726.2  314 aa glutathione synthetase 0.028 ●○○○○ -0.3 -0.302750050319794
Escherichia coli M12  CO715_07455  ATI05564.1  187 aa hypothetical protein 2.4e-7 ●○○○○ -0.3 -0.302028917403635
Acinetobacter baumannii ATCC 17978  A1S_1910  ABO12337.2  758 aa ATP-binding protease component 0.025 ●○○○○ -0.3 -0.301848596253259
Porphyromonas gingivalis ATCC 33277  PGN_1099  WP_012458027.1  B2RJS3  164 aa metallophosphoesterase 6.1e-6 ●○○○○ -0.3 -0.300691834262908
Porphyromonas gingivalis ATCC 33277  PGN_0404  WP_012457485.1  B2RHS8  134 aa rhodanese-like domain-containing protein 1.5e-5 ●○○○○ -0.3 -0.300691834262908
Acinetobacter baumannii ATCC 17978  A1S_2450  ABO12868.2  573 aa putative pyruvate decarboxylase 0.028 ●○○○○ -0.3 -0.300442574544565
Escherichia coli M12  CO715_10645  ATI06114.1  298 aa oxidoreductase 5.6e-9 ●○○○○ -0.3 -0.299942457261146
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4958  AIK83484.1  245 aa binding-protein-dependent transport system innermembrane component family protein 0.00033 ●○○○○ -0.3 -0.29989873717491
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4941  AIK83467.1  132 aa lrgA family protein 0.0019 ●○○○○ -0.3 -0.298914639646587
Acinetobacter baumannii ATCC 17978  A1S_2939  ABO13344.2  785 aa ATPase E1-E2 type:Copper-translocating P-type ATPase:Heavy metal translocating P-type ATPase 0.027 ●○○○○ -0.3 -0.298849192950112
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2703  AIK81293.1  477 aa heavy metal sensor kinase family protein <1e-323 ●○○○○ -0.3 -0.298423242874373
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2899  AIK81488.1  503 aa putative carbohydrate kinase <1e-323 ●○○○○ -0.3 -0.298011576379226
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2490  AIK81087.1  574 aa acetolactate synthase, large subunit, biosynthetic type <1e-323 ●○○○○ -0.3 -0.297909934409701
Escherichia coli M12  CO715_04475  ATI05058.1  438 aa MFS transporter 0.00037 ●○○○○ -0.3 -0.29743870509016
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3523  AIK82079.1  551 aa lldP lactate transporter <1e-323 ●○○○○ -0.3 -0.297327126411976
Porphyromonas gingivalis ATCC 33277  PGN_1093  WP_012458021.1  B2RJR7  443 aa DUF3078 domain-containing protein 2.1e-9 ●○○○○ -0.3 -0.29662399759414
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3673  AIK82228.1  728 aa 1,4-alpha-glucan branching enzyme <1e-323 ●○○○○ -0.3 -0.296157055612856
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0484  NP_232876.1  Q9KM97  95 aa hypothetical protein 0.00066 ●○○○○ -0.3 -0.295733581620268
Escherichia coli M12  CO715_07380  ATI05551.1  105 aa heat-shock protein HspQ 0.00015 ●○○○○ -0.3 -0.295352244947671
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3174  AIK81746.1  398 aa tetratricopeptide repeat family protein <1e-323 ●○○○○ -0.3 -0.295048639175677
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0121  NP_232522.1  Q9KN44  421 aa hypothetical protein 0.0083 ●○○○○ -0.29 -0.29487280066822
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3636  AIK82191.1  208 aa yhhN-like family protein <1e-323 ●○○○○ -0.29 -0.293948168137815
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2589  AIK81186.1  215 aa bacterial virulence factor hemolysin family protein 7.3e-12 ●○○○○ -0.29 -0.293945380834143
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0113  NP_232514.1  Q9KN52  158 aa hypothetical protein 1.4e-5 ●○○○○ -0.29 -0.29377632974709
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2846  AIK81435.1  114 aa AIG2-like family protein 1.3e-6 ●○○○○ -0.29 -0.293285601823746
Escherichia coli M12  CO715_00845  ATI04408.1  382 aa D-galactonate dehydratase 2 3.7e-18 ●○○○○ -0.29 -0.293265784805183
Escherichia coli M12  CO715_00370  ATI04324.1  140 aa hypothetical protein 2.1e-13 ●○○○○ -0.29 -0.292848492776685
Escherichia coli M12  CO715_16390  ATI07154.1  536 aa thiamine/thiamine pyrophosphate ABC transporter permease ThiP 0.017 ●○○○○ -0.29 -0.292848492776685
Escherichia coli M12  CO715_14445  ATI06802.1  111 aa universal stress protein B 9.1e-9 ●○○○○ -0.29 -0.292639846762436
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4717  AIK83251.1  229 aa cupin domain protein 0.036 ●○○○○ -0.29 -0.292407691706183
Escherichia coli M12  CO715_10655  ATI06116.1  199 aa TetR/AcrR family transcriptional regulator 0.00043 ●○○○○ -0.29 -0.292222554733938
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2533  AIK81130.1  1074 aa carB 9.9e-5 ●○○○○ -0.29 -0.29192513884142
Escherichia coli M12  CO715_19355  ATI07684.1  104 aa thiosulfate sulfurtransferase PspE 0.012 ●○○○○ -0.29 -0.291805262705441
Porphyromonas gingivalis ATCC 33277  PGN_1309  WP_012458171.1  B2RKD3  724 aa ferrous iron transport protein B 1.3e-10 ●○○○○ -0.29 -0.2913843340917
Escherichia coli M12  CO715_01795  ATI04574.1  109 aa protein YjdP 2.8e-31 ●○○○○ -0.29 -0.291179324662694
Escherichia coli M12  CO715_22710  ATI08289.1  239 aa purine-nucleoside phosphorylase 5.1e-5 ●○○○○ -0.29 -0.290762032634196
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2598  NP_232226.1  Q9KNY2  rlmB  247 aa 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB 0.00015 ●○○○○ -0.29 -0.290640668234331
Porphyromonas gingivalis ATCC 33277  PGN_1543  WP_012458361.1  B2RL17  219 aa hypothetical protein 1.5e-5 ●○○○○ -0.29 -0.290338054096837
Porphyromonas gingivalis ATCC 33277  PGN_1036  WP_039417209.1  B2RJL0  163 aa DNA-deoxyinosine glycosylase <1e-323 ●○○○○ -0.29 -0.289856723068492
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3571  AIK82126.1  327 aa dppD <1e-323 ●○○○○ -0.29 -0.28965565728704
Escherichia coli M12  CO715_17610  ATI08848.1  210 aa transcriptional regulator 7.6e-23 ●○○○○ -0.29 -0.289092864520205
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1938  NP_231572.1  Q9KQR0  149 aa hypothetical protein 0.002 ●○○○○ -0.29 -0.288933698498075
Porphyromonas gingivalis ATCC 33277  PGN_1402  WP_012458245.1  B2RKM6  309 aa amidinotransferase 1.7e-5 ●○○○○ -0.29 -0.288605832404283
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3388  AIK81945.1  277 aa eamA-like transporter family protein 0.00034 ●○○○○ -0.29 -0.287987121622977
Acinetobacter baumannii ATCC 17978  A1S_2625  ABO13042.2  548 aa putative membrane protein 0.046 ●○○○○ -0.29 -0.287237464538029
Acinetobacter baumannii ATCC 17978  A1S_0576  ABO11029.2  272 aa hypothetical protein 0.034 ●○○○○ -0.29 -0.287207857267592
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1870  NP_231504.1  Q9KQX7  220 aa hypothetical protein 0.029 ●○○○○ -0.29 -0.286724081810757
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