Browse BacFITBase

Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

Download Table  
Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1700  AIK80320.1  444 aa DEAD-box-containing ATP-dependent RNA helicase family member 0.00076 ●○○○○ -0.26 -0.256406520560127
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1549  NP_231189.1  Q9KRT7  434 aa glycerol-3-phosphate ABC transporter substrate-binding protein 5.6e-5 ●○○○○ -0.26 -0.256395532717518
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1717  NP_231353.1  Q9KRC5  cmoM  260 aa metallothionein SmtA 1.1e-7 ●○○○○ -0.26 -0.255881664766107
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4358  AIK82901.1  591 aa L-fucose isomerase <1e-323 ●○○○○ -0.26 -0.2557319645789
Escherichia coli M12  CO715_05575  ATI05245.1  124 aa hypothetical protein 2.8e-9 ●○○○○ -0.26 -0.25529221021189
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3151  AIK81723.1  754 aa 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase <1e-323 ●○○○○ -0.26 -0.255248192281561
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1907  AIK80513.1  342 aa S-methyl-5-thioribose-1-phosphate isomerase 0.034 ●○○○○ -0.26 -0.255245622841332
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2632  AIK81226.1  921 aa AAA domain family protein <1e-323 ●○○○○ -0.25 -0.254759012967904
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4573  AIK83111.1  456 aa pepSY-associated TM helix family protein 6.8e-12 ●○○○○ -0.25 -0.254066238762764
Escherichia coli M12  CO715_16775  ATI07226.1  394 aa MFS transporter 1.7e-11 ●○○○○ -0.25 -0.253831688112148
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2026  AIK80632.1  372 aa periplasmic binding family protein 0.018 ●○○○○ -0.25 -0.25377619102056
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0608  NP_232997.1  Q9KLY3  224 aa nucleotidase 0.00031 ●○○○○ -0.25 -0.253025807807715
Escherichia coli M12  CO715_23845  ATI08474.1  446 aa low-affinity gluconate transporter 0.0081 ●○○○○ -0.25 -0.252579812026655
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2700  AIK81290.1  373 aa cupin superfamily protein 9.4e-5 ●○○○○ -0.25 -0.252577706602095
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0731  NP_233118.1  Q9KLL2  101 aa hypothetical protein 0.004 ●○○○○ -0.25 -0.252388780403664
Escherichia coli M12  CO715_17015  ATI07265.1  90 aa hydrogenase assembly protein HypC 0.04 ●○○○○ -0.25 -0.252371166012406
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3872  AIK82422.1  270 aa mlaF 0.001 ●○○○○ -0.25 -0.251931714519342
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2009  NP_231643.1  Q9KQI9  389 aa hypothetical protein 0.014 ●○○○○ -0.25 -0.251512074236711
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4750  AIK83284.1  323 aa cysteine synthase A 1.3e-14 ●○○○○ -0.25 -0.25053027819887
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0325  NP_232721.1  Q9KML2  107 aa hypothetical protein 0.00072 ●○○○○ -0.25 -0.250482660041098
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1256  AIK79879.1  339 aa L-asparaginase I 0.0039 ●○○○○ -0.25 -0.25033036439997
Escherichia coli M12  CO715_05965  ATI05303.1  486 aa mannitol dehydrogenase family protein 2.2e-14 ●○○○○ -0.25 -0.250284705869917
Escherichia coli M12  CO715_21895  ATI08149.1  415 aa multidrug resistance protein MdtA 0.00059 ●○○○○ -0.25 -0.250076059855668
Escherichia coli M12  CO715_22375  ATI08234.1  309 aa sugar kinase 6.7e-35 ●○○○○ -0.25 -0.249867413841419
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2842  AIK81431.1  500 aa ytfR 7.8e-5 ●○○○○ -0.25 -0.248671767224754
Escherichia coli M12  CO715_16665  ATI08840.1  321 aa hypothetical protein 4.7e-32 ●○○○○ -0.25 -0.248615537755926
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3926  AIK82474.1  523 aa galactarate dehydratase <1e-323 ●○○○○ -0.25 -0.248530692229929
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5149  AIK83670.1  204 aa ead/Ea22-like family protein <1e-323 ●○○○○ -0.25 -0.248431130987133
Escherichia coli M12  CO715_12725  ATI06494.1  263 aa PTS N-acetylgalactosamine transporter subunit IID 1.3e-6 ●○○○○ -0.25 -0.248198245727429
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1666  AIK80286.1  313 aa iaaA 0.001 ●○○○○ -0.25 -0.247949352755589
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4363  AIK82906.1  647 aa ABC transporter, substrate-binding, aliphatic sulfonates family protein 8.8e-7 ●○○○○ -0.25 -0.247887672425625
Porphyromonas gingivalis ATCC 33277  PGN_1927  WP_012458613.1  B2RM51  762 aa CRISPR-associated protein Cas1 4.9e-5 ●○○○○ -0.25 -0.247796033072725
Porphyromonas gingivalis ATCC 33277  PGN_1263  WP_012458151.1  B2RK87  1135 aa hypothetical protein 0.047 ●○○○○ -0.25 -0.247796033072725
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0358  YP_008474272.1  141 aa hypothetical protein 0.0066 ●○○○○ -0.25 -0.247633861932737
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2491  NP_232120.1  Q9KP82  leuB  363 aa 3-isopropylmalate dehydrogenase 0.0014 ●○○○○ -0.25 -0.247559068905029
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2128  NP_231759.1  Q9KQ73  674 aa flagellar hook-length control protein FliK 0.0009 ●○○○○ -0.25 -0.24725022786752
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4255  AIK82800.1  231 aa oligogalacturonate-specific porin family protein <1e-323 ●○○○○ -0.25 -0.247231727654808
Escherichia coli M12  CO715_09415  ATI05910.1  682 aa potassium-transporting ATPase subunit B 3.1e-27 ●○○○○ -0.25 -0.247155015656184
Escherichia coli M12  CO715_04310  ATI05037.1  257 aa NADH pyrophosphatase 0.008 ●○○○○ -0.25 -0.246737723627687
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4212  AIK82757.1  299 aa bacterial regulatory helix-turn-helix, lysR family protein 1.2e-9 ●○○○○ -0.25 -0.246388397108898
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3376  AIK81933.1  184 aa putative dNA-damage-inducible protein D 6.6e-10 ●○○○○ -0.25 -0.24635936689449
Escherichia coli M12  CO715_14795  ATI06870.1  247 aa glycerophosphodiester phosphodiesterase 0.0053 ●○○○○ -0.25 -0.246320431599189
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1666  NP_231302.1  Q9KRH6  220 aa ABC transporter ATP-binding protein 0.00033 ●○○○○ -0.25 -0.246236094603798
Escherichia coli M12  CO715_00155  ATI04285.1  325 aa hypothetical protein 5.3e-20 ●○○○○ -0.25 -0.24611178558494
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1836  AIK80449.1  554 aa asparagine synthase 1.1e-16 ●○○○○ -0.25 -0.246047411335547
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0147  NP_232547.1  Q9KN19  403 aa hydroxyglutarate oxidase 0.00084 ●○○○○ -0.25 -0.246017405655821
Escherichia coli M12  CO715_01320  ATI04491.1  243 aa 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB 1.3e-38 ●○○○○ -0.25 -0.245277201527945
Escherichia coli M12  CO715_14780  ATI06867.1  295 aa sn-glycerol-3-phosphate ABC transporter permease UgpA 1.3e-25 ●○○○○ -0.25 -0.245068555513696
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3969  AIK82517.1  257 aa siderophore-interacting FAD-binding domain protein <1e-323 ●○○○○ -0.25 -0.245014389090511
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5180  AIK83701.1  117 aa hypothetical protein 7.1e-8 ●○○○○ -0.24 -0.244790514929332
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3286  AIK81847.1  127 aa PIN domain protein <1e-323 ●○○○○ -0.24 -0.244702173163797
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4783  AIK83311.1  160 aa cupin domain protein 0.033 ●○○○○ -0.24 -0.244230193839773
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2160  AIK80765.1  264 aa ubiquinol oxidase, subunit II 0.013 ●○○○○ -0.24 -0.244017645017321
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4026  AIK82573.1  210 aa ADP-ribose pyrophosphatase 1.6e-10 ●○○○○ -0.24 -0.243645812570849
Escherichia coli M12  CO715_12620  ATI06475.1  395 aa hypothetical protein 2.6e-16 ●○○○○ -0.24 -0.243608033413954
Escherichia coli M12  CO715_15340  ATI06966.1  274 aa rhamnulose-1-phosphate aldolase 2.4e-5 ●○○○○ -0.24 -0.243608033413954
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4446  AIK82989.1  685 aa fhlA transcriptional activator 0.015 ●○○○○ -0.24 -0.243529563942441
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3616  AIK82171.1  263 aa nickel import ATP-binding protein NikE 1.3e-5 ●○○○○ -0.24 -0.242909090446592
Porphyromonas gingivalis ATCC 33277  PGN_2066  WP_012458727.1  B2RMI9  645 aa ABC transporter ATP-binding protein <1e-323 ●○○○○ -0.24 -0.242337693000396
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3036  AIK81621.1  162 aa cupin domain protein 0.012 ●○○○○ -0.24 -0.242187944835876
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2362  NP_231992.1  Q9KPK5  426 aa threonine synthase 0.005 ●○○○○ -0.24 -0.241535495304066
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0640  NP_233029.1  Q9KLV1  154 aa hypothetical protein 0.047 ●○○○○ -0.24 -0.241191185603676
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0574  NP_232964.1  Q9KM15  893 aa hypothetical protein 4.5e-5 ●○○○○ -0.24 -0.241103787717337
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3521  AIK82077.1  394 aa L-lactate dehydrogenase <1e-323 ●○○○○ -0.24 -0.240736531459168
Porphyromonas gingivalis ATCC 33277  PGN_0482  WP_012457544.1  B2RI06  209 aa hypothetical protein <1e-323 ●○○○○ -0.24 -0.240517309352613
Escherichia coli M12  CO715_08985  ATI05839.1  317 aa LysR family transcriptional regulator 0.00048 ●○○○○ -0.24 -0.239226467114727
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3017  AIK81602.1  807 aa outer membrane assembly complex, YaeT protein <1e-323 ●○○○○ -0.24 -0.239111426170161
Escherichia coli M12  CO715_15270  ATI06954.1  329 aa GNAT family N-acetyltransferase 6.5e-9 ●○○○○ -0.24 -0.238600529071981
Escherichia coli M12  CO715_15545  ATI07000.1  810 aa bifunctional aspartate kinase/homoserine dehydrogenase II 1.5e-13 ●○○○○ -0.24 -0.237348652986488
Escherichia coli M12  CO715_16960  ATI07256.1  136 aa formate hydrogenlyase maturation protein HycH 0.018 ●○○○○ -0.24 -0.23693136095799
Porphyromonas gingivalis ATCC 33277  PGN_1211  WP_012458108.1  B2RK35  289 aa hypothetical protein 2.7e-10 ●○○○○ -0.24 -0.236857315771762
Escherichia coli M12  CO715_14965  ATI06899.1  165 aa DUF1097 domain-containing protein 0.00059 ●○○○○ -0.24 -0.236722714943741
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3476  AIK82032.1  352 aa methylated-DNA-cysteine S-methyltransferase family protein 2.5e-5 ●○○○○ -0.24 -0.236010703960854
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3221  AIK81782.1  612 aa tonB-dependent vitamin B12 receptor <1e-323 ●○○○○ -0.24 -0.235758587858308
Escherichia coli M12  CO715_07765  ATI05617.1  774 aa fe(3+) dicitrate transporter fecA 0.0019 ●○○○○ -0.24 -0.235679484872497
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2106  NP_231738.1  P0C6C8  fur  150 aa ferric uptake regulator 0.0039 ●○○○○ -0.24 -0.23518423887263
Escherichia coli M12  CO715_13645  ATI06657.1  147 aa DNA polymerase III subunit chi 0.00026 ●○○○○ -0.23 -0.234636254801253
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5093  AIK83619.1  77 aa hypothetical protein 0.011 ●○○○○ -0.23 -0.234074979636041
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3920  AIK82468.1  346 aa putative permease family protein 7.9e-9 ●○○○○ -0.23 -0.233727147257077
Escherichia coli M12  CO715_17255  ATI07311.1  425 aa MFS transporter 9.2e-39 ●○○○○ -0.23 -0.233175732701511
Escherichia coli M12  CO715_06735  ATI05437.1  153 aa hypothetical protein 0.0035 ●○○○○ -0.23 -0.233175732701511
Escherichia coli M12  CO715_07630  ATI05597.1  143 aa peroxiredoxin OsmC 0.0012 ●○○○○ -0.23 -0.23150656458752
Porphyromonas gingivalis ATCC 33277  PGN_1525  WP_012458344.1  B2RKZ9  247 aa capsular polysaccharide biosynthesis protein <1e-323 ●○○○○ -0.23 -0.231345728187204
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0783  NP_233169.1  Q9KLG1  215 aa arylesterase 0.0011 ●○○○○ -0.23 -0.231320658112688
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4434  AIK82977.1  282 aa fecCD transport family protein <1e-323 ●○○○○ -0.23 -0.231290948224362
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3351  AIK81908.1  445 aa permease family protein 1.1e-16 ●○○○○ -0.23 -0.230414374909851
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0561  NP_232951.1  Q9KM28  124 aa hypothetical protein 0.0014 ●○○○○ -0.23 -0.230275077688661
Escherichia coli M12  CO715_18470  ATI07528.1  127 aa hypothetical protein 9.1e-5 ●○○○○ -0.23 -0.228585520388036
Escherichia coli M12  CO715_20520  ATI07898.1  198 aa NAD(P)H dehydrogenase (quinone) 0.0075 ●○○○○ -0.23 -0.228585520388036
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3825  AIK82375.1  309 aa quorum sensing transcriptional regulator of LYSR-type <1e-323 ●○○○○ -0.23 -0.228243792486356
Escherichia coli CFT073  c1998  AAN80458.1  Q8FHB1  folM  240 aa Hypothetical oxidoreductase ydgB 0.026 ●○○○○ -0.23 -0.227929560619045
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5086  AIK83612.1  227 aa virB8 family protein 6.0e-6 ●○○○○ -0.23 -0.227880414762346
Escherichia coli M12  CO715_02690  ATI04739.1  571 aa hydrogenase large subunit 2.7e-9 ●○○○○ -0.23 -0.227542290316791
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2564  AIK81161.1  434 aa sugar (and other) transporter family protein 8.9e-16 ●○○○○ -0.23 -0.227372806326693
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2049  YP_007648026.1  404 aa cytochrome C biogenesis protein CcmI 0.0095 ●○○○○ -0.23 -0.226745201923782
Escherichia coli M12  CO715_02640  ATI04729.1  429 aa uracil/xanthine transporter 0.0011 ●○○○○ -0.23 -0.226081768217049
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2980  AIK81565.1  313 aa periplasmic binding and sugar binding domain of LacI family protein 1.9e-6 ●○○○○ -0.23 -0.226057291683834
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0973  NP_230620.1  Q9KTC9  271 aa hypothetical protein 2.4e-6 ●○○○○ -0.23 -0.225501785079825
Escherichia coli M12  CO715_11855  ATI06339.1  739 aa YgiQ family radical SAM protein 6.0e-8 ●○○○○ -0.22 -0.224829892131556
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1971  AIK80577.1  345 aa oligopeptide/dipeptide ABC transporter, ATP-binding, C-terminal domain protein 1.6e-12 ●○○○○ -0.22 -0.224756773381845
Retrieved entries 6,301–6,400 out of 36,363 total in 7.7 ms (Link to these results)