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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3864  WP_001055305.1  E8XG06  lldP  551 aa L-lactate permease 0.026 ○○○○○ 1.05 1.05385095589365
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2765  CBW18864.1  A0A0H3NGQ6  mig-14  298 aa hypothetical transcriptional regulator 0.025 ○○○○○ 1.05 1.05386668521915
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0427  NP_232821.1  Q9KMD4  52 aa hypothetical protein 0.013 ○○○○○ 1.05 1.05459801743177
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1520  AIK80140.1  400 aa nicotinate phosphoribosyltransferase <1e-323 ○○○○○ 1.06 1.05589051817474
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0266  WP_000154871.1  E8XIS0  dkgB  267 aa 2,5-didehydrogluconate reductase DkgB 0.024 ○○○○○ 1.06 1.05634430324108
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0118  WP_000042325.1  E8XH23  leuB  363 aa 3-isopropylmalate dehydrogenase 0.02 ○○○○○ 1.06 1.05636674958133
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0060  CBW16161.1  A0A0H3NH25  citD2  97 aa citrate lyase acyl carrier protein 0.049 ○○○○○ 1.06 1.05692997587588
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3909  WP_000621352.1  E8XGT5  yicc  287 aa YicC family protein 0.023 ○○○○○ 1.06 1.05735234868396
Escherichia coli M12  CO715_03765  ATI04934.1  128 aa 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase 0.045 ○○○○○ 1.06 1.05834309549894
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1493  NP_231134.1  Q9KRZ0  78 aa hypothetical protein 0.015 ○○○○○ 1.06 1.05908462921395
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2306  WP_000178095.1  E8XDQ3  yeiU  239 aa phosphatase PAP2 family protein 0.021 ○○○○○ 1.06 1.05951527528817
Escherichia coli M12  CO715_03225  ATI04835.1  204 aa DNA-binding response regulator 5.0e-44 ○○○○○ 1.06 1.06084684766993
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4864  AIK83391.1  429 aa major Facilitator Superfamily protein <1e-323 ○○○○○ 1.06 1.06090058282526
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1335  NP_230979.1  Q9KSC3  235 aa GntR family transcriptional regulator 0.034 ○○○○○ 1.06 1.06128768006863
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0799  NP_233185.1  Q9KLE7  168 aa hypothetical protein 4.0e-6 ○○○○○ 1.06 1.06145651841431
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1091  AIK79714.1  584 aa type VI secretion system protein DUF879 <1e-323 ○○○○○ 1.06 1.06173723393131
Porphyromonas gingivalis ATCC 33277  PGN_0150  WP_012457281.1  B2RH24  427 aa DEAD/DEAH box helicase 0.045 ○○○○○ 1.06 1.06180424764255
Porphyromonas gingivalis ATCC 33277  PGN_0150  WP_077094377.1  B2RH24  64 aa hypothetical protein 0.045 ○○○○○ 1.06 1.06180424764255
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4809  AIK83336.1  216 aa cell division protein DedD 5.9e-10 ○○○○○ 1.06 1.06202936089448
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4242  CBW20328.1  A0A0H3NIX3  809 aa hypothetical anaerobic dimethyl sulfoxide reductase chain 0.043 ○○○○○ 1.06 1.06241023357389
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0184  WP_001231776.1  E8XHX3  stiC  848 aa fimbrial outer membrane usher protein 0.035 ○○○○○ 1.06 1.06248130081868
Escherichia coli M12  CO715_02740  ATI04749.1  344 aa outer membrane protein assembly factor BamC 0.016 ○○○○○ 1.06 1.06314195382666
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0341  NP_229995.1  Q9KV17  orn  181 aa oligoribonuclease 0.015 ○○○○○ 1.06 1.06345745045751
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1217  WP_000291338.1  E8XFE7  ycfX  303 aa N-acetylglucosamine kinase 0.02 ○○○○○ 1.06 1.06370880918257
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1386  AIK80009.1  299 aa oxidoreductase, NAD-binding Rossmann fold family protein <1e-323 ○○○○○ 1.06 1.06450648473584
Escherichia coli M12  CO715_03445  ATI04874.1  668 aa bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC 6.8e-21 ○○○○○ 1.06 1.06460247592641
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1165  WP_001259729.1  E8XET8  307 aa Gfo/Idh/MocA family oxidoreductase 0.028 ○○○○○ 1.06 1.06467515832707
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3999  WP_000790665.1  E8XHQ8  torA  850 aa trimethylamine-N-oxide reductase TorA 0.013 ○○○○○ 1.06 1.06468351721684
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1093  AIK79716.1  1082 aa intracellular multiplication and human macrophage-killing family protein 2.2e-16 ○○○○○ 1.07 1.06580284458467
Acinetobacter baumannii ATCC 17978  A1S_1782  ABO12209.2  267 aa hypothetical protein 3.8e-5 ○○○○○ 1.07 1.06587196309346
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0499  WP_000440523.1  E8X865  311 aa Rpn family recombination-promoting nuclease/putative transposase 0.019 ○○○○○ 1.07 1.06615067011048
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3172  WP_000134791.1  E8X9J7  252 aa transcriptional regulator 0.015 ○○○○○ 1.07 1.06637392506759
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2723  NP_232350.1  P45784  epsN  252 aa general secretion pathway protein N 0.00043 ○○○○○ 1.07 1.06647327729542
Acinetobacter baumannii ATCC 17978  A1S_1661  ABO12088.2  192 aa Fructose-26-bisphosphatase 0.0021 ○○○○○ 1.07 1.06651891157261
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0469  NP_230123.1  Q9KUP6  243 aa 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.029 ○○○○○ 1.07 1.06656571716578
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3418  AIK81975.1  351 aa prpF family protein 1.3e-12 ○○○○○ 1.07 1.06680065148558
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0846  NP_233232.1  Q9KLA0  204 aa hypothetical protein 0.021 ○○○○○ 1.07 1.06687131010583
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4394  CBW20482.1  A0A0H3NPT9  467 aa hypothetical membrane protein 0.042 ○○○○○ 1.07 1.06696175040872
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2359  AIK80956.1  280 aa nlpC/P60 family protein <1e-323 ○○○○○ 1.07 1.06794962372966
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0985  NP_233369.1  Q9KKW5  959 aa oxidoreductase/iron-sulfur cluster-binding protein 0.0024 ○○○○○ 1.07 1.0681601630443
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2991  WP_000158074.1  E8XKY0  hycA  153 aa formate hydrogenlyase regulator HycA 0.033 ○○○○○ 1.07 1.06834774373494
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4593  WP_001119448.1  E8XAS1  ytfB  211 aa hypothetical protein 0.019 ○○○○○ 1.07 1.06854389825326
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1177  WP_001518955.1  E8XEV0  flgI  365 aa flagellar basal body P-ring protein FlgI 0.015 ○○○○○ 1.07 1.06909010724652
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3262  WP_000839739.1  E8XAG3  speC  711 aa ornithine decarboxylase 0.036 ○○○○○ 1.07 1.06976638068926
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1468  AIK80089.1  358 aa PTS system, Fru family, IIC component domain protein <1e-323 ○○○○○ 1.07 1.07047391380788
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4614  AIK83148.1  86 aa 4Fe-4S binding domain protein <1e-323 ○○○○○ 1.07 1.07061475190072
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3732  WP_000778873.1  E8XF77  panZ  127 aa aspartate 1-decarboxylase autocleavage activator PanM 0.021 ○○○○○ 1.07 1.0713705225749
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0277  WP_000367626.1  E8XIT0  351 aa hypothetical protein 0.037 ○○○○○ 1.07 1.07141052642659
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1081  NP_233462.1  Q9KKM2  220 aa hypothetical protein 3.0e-5 ○○○○○ 1.07 1.07149631782016
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1162  AIK79785.1  459 aa permease for cytosine/purines, uracil, thiamine,allantoin family protein <1e-323 ○○○○○ 1.07 1.07174935730775
Escherichia coli M12  CO715_13435  ATI06621.1  405 aa MFS transporter 3.1e-35 ○○○○○ 1.07 1.07294831649636
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1556  NP_231196.1  Q9KRT0  120 aa hypothetical protein 0.0043 ○○○○○ 1.07 1.07389656059504
Acinetobacter baumannii ATCC 17978  A1S_1760  ABO12187.1  248 aa hypothetical protein 0.0044 ○○○○○ 1.07 1.07438589701215
Porphyromonas gingivalis ATCC 33277  PGN_0481  WP_012457543.1  B2RI05  422 aa hypothetical protein <1e-323 ○○○○○ 1.07 1.07448337327948
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1473  AIK80094.1  255 aa phytanoyl-CoA dioxygenase family protein 0.022 ○○○○○ 1.07 1.07488502458736
Acinetobacter baumannii ATCC 17978  A1S_0661  ABO11110.1  400 aa phage integrase family protein 0.00014 ○○○○○ 1.08 1.07553682930238
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2713  CBW18814.1  A0A0H3NEX0  565 aa conserved hypothetical protein 0.043 ○○○○○ 1.08 1.07562117710754
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3813  WP_000637070.1  E8XFV6  yhjY  234 aa autotransporter outer membrane beta-barrel domain-containing protein 0.011 ○○○○○ 1.08 1.07586934549585
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1888  AIK80494.1  386 aa methionine aminotransferase, PLP-dependent <1e-323 ○○○○○ 1.08 1.07590240597058
Escherichia coli M12  CO715_04885  ATI05126.1  351 aa FAD:protein FMN transferase ApbE 0.00019 ○○○○○ 1.08 1.07670394475284
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2473  NP_232102.1  Q9KPA0  77 aa hypothetical protein 0.0024 ○○○○○ 1.08 1.07726766449267
Escherichia coli M12  CO715_09055  ATI05853.1  250 aa 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 0.042 ○○○○○ 1.08 1.07732988279559
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0846  WP_000007060.1  E8XBT3  rhlE  454 aa ATP-dependent RNA helicase RhlE 0.011 ○○○○○ 1.08 1.07742939340703
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2188  NP_231819.1  P0C6C3  flaA  379 aa flagellin 0.02 ○○○○○ 1.08 1.07756373709074
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2277  NP_231908.1  Q9KPT5  gpt  154 aa xanthine-guanine phosphoribosyltransferase 0.048 ○○○○○ 1.08 1.077707518017
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0766  NP_233152.2  Q9KLH8  102 aa cytochrome c554 0.00043 ○○○○○ 1.08 1.07776858242934
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1940  NP_231574.1  Q9KQQ8  220 aa hypothetical protein 0.00013 ○○○○○ 1.08 1.07842383550828
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2521  AIK81118.1  232 aa dpiA-phosphorylated DNA binding transcriptional dual regulator <1e-323 ○○○○○ 1.08 1.0788354568422
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3816  WP_000148453.1  E8XFV9  bisC  777 aa molybdopterin guanine dinucleotide-containing S/N-oxide reductase 0.017 ○○○○○ 1.08 1.07887339888554
Escherichia coli M12  CO715_04130  ATI05002.1  289 aa phosphoribulokinase 0.018 ○○○○○ 1.08 1.07920769692383
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3703  WP_000253995.1  E8XEN9  glgC  431 aa glucose-1-phosphate adenylyltransferase 0.017 ○○○○○ 1.08 1.07940846078828
Escherichia coli M12  CO715_16375  ATI07151.1  552 aa transcriptional regulator SgrR 2.2e-56 ○○○○○ 1.08 1.08025092699507
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5080  AIK83606.1  248 aa putative mobilization protein 3.9e-5 ○○○○○ 1.08 1.08066501957086
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4469  WP_000832536.1  E8X9S4  actP  549 aa cation/acetate symporter ActP 0.021 ○○○○○ 1.08 1.08079615385556
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4095  CBW20183.1  A0A0H3NV60  114 aa conserved hypothetical protein 0.034 ○○○○○ 1.08 1.08133718769298
Acinetobacter baumannii ATCC 17978  A1S_0657  ABO11106.2  105 aa transposase 0.0043 ○○○○○ 1.08 1.08212079107181
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2738  WP_000788827.1  E8XHL0  230 aa Replication protein 14 0.018 ○○○○○ 1.08 1.08217511360714
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0040  NP_229699.1  Q9KVU9  215 aa hemolysin 0.016 ○○○○○ 1.08 1.08460525021477
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3640  WP_000185211.1  E8XEH6  tsga  393 aa MFS transporter TsgA 0.028 ○○○○○ 1.08 1.08492687092182
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0209  CBW16311.2  A0A0H3NHI0  dgt  435 aa Deoxyguanosinetriphosphate triphosphohydrolase 0.041 ○○○○○ 1.08 1.08496420264854
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1066  NP_233448.1  Q9KKN6  79 aa hypothetical protein 0.0039 ○○○○○ 1.09 1.08525789709666
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4054  WP_000763722.1  E8XIJ5  mioC  147 aa FMN-binding protein MioC 0.023 ○○○○○ 1.09 1.08536890382382
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2324  AIK80928.1  206 aa ubiquinone oxidoreductase, Na(+)-translocating, D subunit 0.047 ○○○○○ 1.09 1.08575977876686
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3412  WP_000719916.1  E8XC72  475 aa PTS galactitol transporter subunit IIC 0.0012 ○○○○○ 1.09 1.08660754837261
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3073  WP_001173663.1  E8X8L2  cysC  201 aa adenylyl-sulfate kinase 0.014 ○○○○○ 1.09 1.08672207388697
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4272  AIK82818.1  333 aa ascG transcriptional repressor 3.0e-8 ○○○○○ 1.09 1.08699737935449
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5148  AIK83669.1  147 aa hypothetical protein <1e-323 ○○○○○ 1.09 1.08762939839488
Acinetobacter baumannii ATCC 17978  A1S_3186  ABO13581.2  291 aa putative signal peptide 2.8e-5 ○○○○○ 1.09 1.08872524512178
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1711  AIK80331.1  368 aa ABC-2 type transporter family protein <1e-323 ○○○○○ 1.09 1.08875535031375
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4781  AIK83309.1  302 aa cynR transcriptional dual regulator <1e-323 ○○○○○ 1.09 1.08879535083627
Escherichia coli M12  CO715_02390  ATI04683.1  159 aa phosphopantetheine adenylyltransferase 6.7e-9 ○○○○○ 1.09 1.08880541357927
Porphyromonas gingivalis ATCC 33277  PGN_0348  WP_004583894.1  B2RHM2  uspA  370 aa universal stress protein <1e-323 ○○○○○ 1.09 1.08922531456957
Escherichia coli M12  CO715_19215  ATI07659.1  144 aa universal stress protein UspF 1.4e-30 ○○○○○ 1.09 1.08963999763627
Acinetobacter baumannii ATCC 17978  A1S_1299  ABO11727.1  231 aa hypothetical protein 4.4e-5 ○○○○○ 1.09 1.09002090184701
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2415  CBW18517.1  A0A0H3NFN0  109 aa hypothetical membrane protein 0.035 ○○○○○ 1.09 1.09005909796399
Porphyromonas gingivalis ATCC 33277  PGN_1435  WP_004585076.1  B2RKQ9  71 aa hypothetical protein 2.8e-13 ○○○○○ 1.09 1.09024426429533
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1780  AIK80393.1  264 aa tol-pal system protein YbgF <1e-323 ○○○○○ 1.09 1.09048359445485
Escherichia coli M12  CO715_18605  ATI07550.1  337 aa gfo/Idh/MocA family oxidoreductase 7.7e-32 ○○○○○ 1.09 1.09068322770751
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0930  WP_000447499.1  E8XCQ1  cspD  73 aa cold shock-like protein CspD 0.017 ○○○○○ 1.09 1.09169691989713
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1411  AIK80034.1  312 aa glyoxylate reductase / hydroxypyruvate reductase 7.2e-6 ○○○○○ 1.09 1.09182979024332
Retrieved entries 34,401–34,500 out of 36,363 total in 701.8 ms (Link to these results)