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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1892  AIK80498.1  326 aa ABC sugar (Ribose) transporter, periplasmic substrate-binding subunit 2.2e-12 ○○○○○ 1.42 1.42266032346336
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1113  AIK79736.1  112 aa anti-anti-sigma factor family protein 6.6e-8 ○○○○○ 1.42 1.42283263504198
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1298  AIK79921.1  402 aa hypothetical protein <1e-323 ○○○○○ 1.42 1.42370450660226
Mycobacterium avium subsp. paratuberculosis K10  MAP_3585  AAS06135.1  Q73TY3  391 aa hypothetical protein 0.047 ○○○○○ 1.42 1.42415617794192
Mycobacterium avium subsp. paratuberculosis K10  MAP_3586c  AAS06136.1  Q73TY2  236 aa hypothetical protein 0.047 ○○○○○ 1.42 1.42415617794192
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1237  AIK79860.1  406 aa astC <1e-323 ○○○○○ 1.43 1.42525241067614
Mycobacterium avium subsp. paratuberculosis K10  MAP_1247  AAS03564.1  Q740U5  286 aa hypothetical protein 0.047 ○○○○○ 1.43 1.42531232787079
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1438  AIK80058.1  131 aa hypothetical protein 7.0e-5 ○○○○○ 1.43 1.42625590872932
Porphyromonas gingivalis ATCC 33277  PGN_1713  WP_012458477.1  B2RLI7  lpxE  445 aa phosphatase PAP2 family protein 9.4e-6 ○○○○○ 1.43 1.42673821007425
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0993  NP_233377.1  Q9KKV7  367 aa N-ethylmaleimide reductase 0.00022 ○○○○○ 1.43 1.42703560116984
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1387  AIK80010.1  217 aa hypothetical protein <1e-323 ○○○○○ 1.43 1.4272697181222
Streptococcus pyogenes M1 5448  SP5448_00955  WP_002986345.1  398 aa glycine betaine/L-proline ABC transporter ATP-binding protein 0.0089 ○○○○○ 1.43 1.4274081413072
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1026  AIK79649.1  1300 aa ATP-dependent helicase HrpA <1e-323 ○○○○○ 1.43 1.4274834982259
Escherichia coli M12  CO715_23650  ATI08440.1  63 aa hypothetical protein 0.035 ○○○○○ 1.43 1.42764654071942
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1216  AIK79839.1  222 aa 2-deoxyglucose-6-phosphatase 3.0e-15 ○○○○○ 1.43 1.42770547779557
Mycobacterium avium subsp. paratuberculosis K10  MAP_3819  AAS06369.1  Q73T99  211 aa hypothetical protein 0.047 ○○○○○ 1.43 1.4277722416745
Acinetobacter baumannii ATCC 17978  A1S_0675  ABO11123.2  271 aa dihydropteroate synthase 3.2e-5 ○○○○○ 1.43 1.4281513553751
Porphyromonas gingivalis ATCC 33277  PGN_1494  WP_012458316.1  B2RKW8  376 aa radical SAM family heme chaperone HemW <1e-323 ○○○○○ 1.43 1.42823251129904
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1598  CBW17693.1  A0A0H3NBZ8  276 aa hypothetical exported protein 0.001 ○○○○○ 1.43 1.42841194059461
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2813  WP_000533859.1  E8XIG7  469 aa TolC family type I secretion outer membrane protein 0.00096 ○○○○○ 1.43 1.42879217740505
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3961  WP_000879181.1  E8XHM1  uhpT  463 aa hexose-6-phosphate:phosphate antiporter 0.00091 ○○○○○ 1.43 1.42998401040545
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4039  WP_000213163.1  E8XHU8  585 aa SgrR family transcriptional regulator 0.00088 ○○○○○ 1.43 1.43028493095655
Mycobacterium avium subsp. paratuberculosis K10  MAP_3812c  AAS06362.1  Q73TA6  271 aa hypothetical protein 0.047 ○○○○○ 1.43 1.43141689210676
Acinetobacter baumannii ATCC 17978  A1S_1997  ABO12424.2  162 aa molybdopterin converting factor large subunit 0.00048 ○○○○○ 1.43 1.43184063357589
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2330  WP_000003792.1  E8XDS5  172 aa HK97 family phage prohead protease 2.1e-5 ○○○○○ 1.43 1.43293191392941
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1873  AIK80479.1  68 aa tatE 6.5e-6 ○○○○○ 1.43 1.43307779819208
Porphyromonas gingivalis ATCC 33277  PGN_0845  WP_012457822.1  B2RJ19  119 aa hypothetical protein 0.00017 ○○○○○ 1.43 1.43338057605222
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1067  CBW17163.1  A0A0H3NAH1  nanE  226 aa conserved hypothetical protein 0.0071 ○○○○○ 1.43 1.43344519129971
Mycobacterium avium subsp. paratuberculosis K10  MAP_2043  AAS04360.1  Q73YB3  yjcE  536 aa YjcE 0.047 ○○○○○ 1.43 1.43352754717242
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1528  AIK80148.1  396 aa aspC 0.0055 ○○○○○ 1.43 1.43422476267253
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4994  AIK83520.1  453 aa peptidase U32 family protein <1e-323 ○○○○○ 1.43 1.43495726335834
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2360  AIK80957.1  232 aa nlpE N-terminal domain protein <1e-323 ○○○○○ 1.44 1.43521010668928
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3020  WP_001055577.1  E8XL09  iacP  82 aa acyl carrier protein 0.0078 ○○○○○ 1.44 1.43522234995467
Porphyromonas gingivalis ATCC 33277  PGN_0128  WP_012457267.1  B2RH02  479 aa DUF3868 domain-containing protein <1e-323 ○○○○○ 1.44 1.43553789701197
Mycobacterium avium subsp. paratuberculosis K10  MAP_1075c  AAS03392.1  Q741L5  88 aa hypothetical protein 0.047 ○○○○○ 1.44 1.43578866316903
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1125  AIK79748.1  278 aa oxidoreductase, aldo/keto reductase family 5.1e-6 ○○○○○ 1.44 1.43664419760115
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0722  WP_001292402.1  E8XA53  speF  732 aa ornithine decarboxylase SpeF 0.0037 ○○○○○ 1.44 1.43676866251076
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0771  WP_000124676.1  E8XAY1  tolR  142 aa colicin uptake protein TolR 0.0028 ○○○○○ 1.44 1.43691074649949
Mycobacterium avium subsp. paratuberculosis K10  MAP_1538  AAS03855.1  Q73ZR3  279 aa hypothetical protein 0.046 ○○○○○ 1.44 1.43801156774322
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1893  AIK80499.1  500 aa ABC transporter family protein 4.3e-10 ○○○○○ 1.44 1.43810134318385
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3717  WP_000675710.1  E8XEQ3  344 aa phosphotriesterase 0.0029 ○○○○○ 1.44 1.43813036699206
Mycobacterium avium subsp. paratuberculosis K10  MAP_2084  AAS04401.1  Q73Y73  484 aa hypothetical protein 0.046 ○○○○○ 1.44 1.43849270906576
Mycobacterium avium subsp. paratuberculosis K10  MAP_2771c  AAS05088.1  Q73W89  425 aa hypothetical protein 0.046 ○○○○○ 1.44 1.4386680217245
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4056  WP_000845121.1  E8XIJ7  asnA  330 aa aspartate--ammonia ligase 0.023 ○○○○○ 1.44 1.43963855146123
Mycobacterium avium subsp. paratuberculosis K10  MAP_0079  AAS02396.1  Q744W6  246 aa hypothetical protein 0.046 ○○○○○ 1.44 1.44034483213395
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1351  WP_001082196.1  E8XGF3  aroH  348 aa 3-deoxy-7-phosphoheptulonate synthase AroH 1.1e-5 ○○○○○ 1.44 1.44037122248283
Mycobacterium avium subsp. paratuberculosis K10  MAP_0332  AAS02649.1  Q744K9  355 aa hypothetical protein 0.046 ○○○○○ 1.44 1.44115027863699
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1206  AIK79829.1  235 aa short chain dehydrogenase family protein 1.1e-14 ○○○○○ 1.44 1.44115068130335
Acinetobacter baumannii ATCC 17978  A1S_0646  ABO11095.2  1090 aa IcmB protein 4.7e-10 ○○○○○ 1.44 1.44160710787537
Mycobacterium avium subsp. paratuberculosis K10  MAP_0111  AAS02428.1  Q745A0  371 aa hypothetical protein 0.046 ○○○○○ 1.44 1.4429241133244
Mycobacterium avium subsp. paratuberculosis K10  MAP_2473  AAS04790.1  Q73X37  145 aa hypothetical protein 0.046 ○○○○○ 1.44 1.44380332805919
Mycobacterium avium subsp. paratuberculosis K10  MAP_3212  AAS05760.1  Q73V04  nuoL  628 aa NuoL 0.046 ○○○○○ 1.44 1.44394224399846
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0084  WP_001737995.1  E8XGY9  yaaU  446 aa MFS transporter 0.0022 ○○○○○ 1.44 1.44452690508506
Escherichia coli M12  CO715_21775  ATI08126.1  266 aa bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 2.8e-21 ○○○○○ 1.44 1.44454686787358
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0420  WP_000930727.1  E8XKI7  malZ  605 aa maltodextrin glucosidase 0.0015 ○○○○○ 1.44 1.44486774899408
Mycobacterium avium subsp. paratuberculosis K10  MAP_2943c  AAS05260.1  Q73VR8  rlmN  364 aa hypothetical protein 0.046 ○○○○○ 1.45 1.44678451423156
Mycobacterium avium subsp. paratuberculosis K10  MAP_1264  AAS03581.1  Q740S8  ilvA  427 aa IlvA 0.046 ○○○○○ 1.45 1.44744150227697
Escherichia coli M12  CO715_04850  ATI05119.1  608 aa two-component system sensor histidine kinase AtoS 9.2e-16 ○○○○○ 1.45 1.44746791207307
Mycobacterium avium subsp. paratuberculosis K10  MAP_1717  AAS04034.1  Q73Z86  214 aa hypothetical protein 0.046 ○○○○○ 1.45 1.44791055127562
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3373  WP_000121523.1  E8XBE7  fadH  672 aa NADPH-dependent 2,4-dienoyl-CoA reductase 0.0011 ○○○○○ 1.45 1.44920422582377
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4431  AIK82974.1  293 aa bacterial regulatory helix-turn-helix, lysR family protein <1e-323 ○○○○○ 1.45 1.45025493611479
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1029  NP_233413.1  Q9KKS1  656 aa glycogen operon protein GlgX 0.0046 ○○○○○ 1.45 1.45031669989043
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1038  AIK79661.1  165 aa phenylacetate-CoA oxygenase, PaaJ subunit 2.6e-15 ○○○○○ 1.45 1.45085511225435
Acinetobacter baumannii ATCC 17978  A1S_1912  ABO12339.2  250 aa hypothetical protein 3.2e-7 ○○○○○ 1.45 1.45116803573093
Porphyromonas gingivalis ATCC 33277  PGN_0470  WP_012457532.1  B2RHZ4  358 aa peptidase S41 0.0001 ○○○○○ 1.45 1.45128567785264
Escherichia coli M12  CO715_20140  ATI07828.1  356 aa tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA 9.9e-13 ○○○○○ 1.45 1.45184947837229
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1582  CBW17677.1  A0A0H3NBY3  ynaF  144 aa conserved hypothetical protein 0.00038 ○○○○○ 1.45 1.45212714938121
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0153  NP_232553.1  Q9KN13  103 aa monovalent cation/H+ antiporter subunit F 0.0051 ○○○○○ 1.45 1.45414100733424
Porphyromonas gingivalis ATCC 33277  PGN_1364  WP_012458220.1  B2RKI8  234 aa peptidylprolyl isomerase 2.7e-5 ○○○○○ 1.45 1.45419992012206
Mycobacterium avium subsp. paratuberculosis K10  MAP_1235  AAS03552.1  Q740V7  444 aa hypothetical protein 0.045 ○○○○○ 1.45 1.45473955318795
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2214  AIK80819.1  39 aa hypothetical protein <1e-323 ○○○○○ 1.46 1.45523005057372
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3079  WP_000144831.1  E8X8L8  cas1  306 aa type I-E CRISPR-associated endonuclease Cas1 0.0044 ○○○○○ 1.46 1.45564640544909
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2054  AIK80660.1  90 aa hypothetical protein 1.6e-6 ○○○○○ 1.46 1.4561063980394
Mycobacterium avium subsp. paratuberculosis K10  MAP_3365c  AAS05915.1  Q73UK3  505 aa hypothetical protein 0.045 ○○○○○ 1.46 1.45635758287231
Mycobacterium avium subsp. paratuberculosis K10  MAP_3043c  AAS05591.1  Q73VH1  388 aa hypothetical protein 0.045 ○○○○○ 1.46 1.457937852013
Acinetobacter baumannii ATCC 17978  A1S_1557  ABO11984.2  A3M4Z0  kdsB  253 aa 3-deoxy-manno-octulosonate cytidylyltransferase 0.034 ○○○○○ 1.46 1.45958701481689
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1425  AIK80046.1  223 aa phage integrase 5.2e-12 ○○○○○ 1.46 1.46051904185038
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1249  AIK79872.1  416 aa gdhA 0.0073 ○○○○○ 1.46 1.46107355916097
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1788  NP_231423.1  Q9K2L3  231 aa hypothetical protein 0.0064 ○○○○○ 1.46 1.46115133530296
Acinetobacter baumannii ATCC 17978  A1S_2038  ABO12465.2  146 aa hypothetical protein 3.4e-8 ○○○○○ 1.46 1.46184958619989
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3366  WP_000237776.1  E8XBE1  mug  168 aa G/U mismatch-specific DNA glycosylase 0.003 ○○○○○ 1.46 1.46266211209932
Mycobacterium avium subsp. paratuberculosis K10  MAP_4220  AAS06770.1  Q73S56  306 aa hypothetical protein 0.045 ○○○○○ 1.46 1.46368047991516
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2579  AIK81176.1  157 aa creA family protein 1.0e-10 ○○○○○ 1.46 1.46411839289676
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2147  CBW18243.1  A0A0H3NEX3  yohC  195 aa hypothetical membrane protein 0.017 ○○○○○ 1.46 1.46435481943418
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1155  AIK79777.1  773 aa bacterial regulatory helix-turn-helix, AraC family protein 6.6e-15 ○○○○○ 1.46 1.46456808090346
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2119  WP_000153648.1  E8XBY8  cbiB  319 aa cobalamin biosynthesis protein 3.2e-6 ○○○○○ 1.46 1.46458353035324
Mycobacterium avium subsp. paratuberculosis K10  MAP_3575  AAS06125.1  Q73TZ3  211 aa hypothetical protein 0.045 ○○○○○ 1.46 1.46490397775391
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4155  WP_000459635.1  E8XJG5  tatD  260 aa 3'-5' ssDNA/RNA exonuclease TatD 0.0029 ○○○○○ 1.47 1.46540799544517
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1544  AIK80164.1  750 aa DNA internalization-related competence protein ComEC/Rec2 <1e-323 ○○○○○ 1.47 1.46569317271517
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0902  CBW16998.1  A0A0H3NEY3  dmsA  814 aa anaerobic dimethyl sulfoxide reductase chain A precursor 0.0032 ○○○○○ 1.47 1.46596331657799
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3354  AIK81911.1  319 aa putative transcriptional regulator LysR-type <1e-323 ○○○○○ 1.47 1.4664160441484
Escherichia coli M12  CO715_07205  ATI05523.1  264 aa spermidine/putrescine ABC transporter permease 0.007 ○○○○○ 1.47 1.46687199139821
Mycobacterium avium subsp. paratuberculosis K10  MAP_1035c  AAS03352.1  Q741Q3  203 aa hypothetical protein 0.045 ○○○○○ 1.47 1.4669052026251
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1013  AIK79636.1  446 aa succinylarginine dihydrolase <1e-323 ○○○○○ 1.47 1.46722121522921
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1409  AIK80032.1  184 aa nitrate reductase delta subunit <1e-323 ○○○○○ 1.47 1.46739680535854
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1110  AIK79733.1  253 aa short chain dehydrogenase family protein 3.5e-5 ○○○○○ 1.47 1.46859723988137
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1652  AIK80272.1  410 aa sugar (and other) transporter family protein <1e-323 ○○○○○ 1.47 1.46911643678001
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1341  AIK79964.1  572 aa sorbitol phosphotransferase enzyme II family protein 1.1e-7 ○○○○○ 1.47 1.47003980247925
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1031  AIK79654.1  438 aa phenylacetate-CoA ligase <1e-323 ○○○○○ 1.47 1.47163698929055
Escherichia coli M12  CO715_11255  ATI06229.1  447 aa glutamate dehydrogenase 4.6e-22 ○○○○○ 1.47 1.47229678776868
Retrieved entries 35,101–35,200 out of 36,363 total in 1476.2 ms (Link to these results)