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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2132  NP_231763.1  Q9X4Q9  fliG  348 aa flagellar motor switch protein G 6.3e-9 ○○○○○ 1.93 1.93061318087801
Mycobacterium avium subsp. paratuberculosis K10  MAP_2503  AAS04820.1  Q73X07  embR  380 aa EmbR_2 0.02 ○○○○○ 1.93 1.9319036405374
Porphyromonas gingivalis ATCC 33277  PGN_0700  WP_039417297.1  B2RIM4  468 aa Gfo/Idh/MocA family oxidoreductase 4.4e-10 ○○○○○ 1.93 1.93204806463627
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1119  NP_230764.1  Q9KSY7  241 aa short chain dehydrogenase 0.00044 ○○○○○ 1.93 1.93240108870886
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0645  WP_002776307.1  A0A0H3PBN9  pstB  246 aa phosphate ABC transporter ATP-binding protein 0.032 ○○○○○ 1.93 1.93251705229
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1871  NP_231505.2  Q9KQX6  166 aa hypothetical protein 0.0058 ○○○○○ 1.93 1.93288795119504
Streptococcus pyogenes M1 5448  SP5448_02320  WP_002988740.1  283 aa site-specific DNA-methyltransferase 0.026 ○○○○○ 1.93 1.93403247578735
Escherichia coli M12  CO715_05830  ATI05284.1  109 aa phage tail protein 0.018 ○○○○○ 1.93 1.93423906331566
Mycobacterium avium subsp. paratuberculosis K10  MAP_1180c  AAS03497.1  Q741B2  qor  331 aa Qor 0.02 ○○○○○ 1.93 1.93431939950517
Mycobacterium avium subsp. paratuberculosis K10  MAP_0158  AAS02475.1  Q745G2  396 aa hypothetical protein 0.02 ○○○○○ 1.94 1.93661347925823
Streptococcus pyogenes M1 5448  SP5448_01135  WP_010921864.1  568 aa ABC transporter ATP-binding protein 0.042 ○○○○○ 1.94 1.93787782177961
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2133  NP_231764.1  Q9KQ69  580 aa flagellar MS-ring protein 0.011 ○○○○○ 1.94 1.93836405911281
Mycobacterium avium subsp. paratuberculosis K10  MAP_1422  AAS03739.1  Q740C9  595 aa hypothetical protein 0.02 ○○○○○ 1.94 1.93858235281941
Mycobacterium avium subsp. paratuberculosis K10  MAP_1955c  AAS04272.1  Q73YK0  ephD  592 aa EphD 0.02 ○○○○○ 1.94 1.93869417556263
Streptococcus pyogenes M1 5448  SP5448_04305  WP_010922385.1  271 aa maltodextrose utilization protein MalA 0.033 ○○○○○ 1.94 1.93883915827768
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0113  WP_002851907.1  A0A0H3PGP1  lctP  560 aa L-lactate permease 0.032 ○○○○○ 1.94 1.93931979008
Mycobacterium avium subsp. paratuberculosis K10  MAP_2842c  AAS05159.1  Q73W19  232 aa hypothetical protein 0.02 ○○○○○ 1.94 1.93983387148705
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1538  AIK80157.1  259 aa hypothetical protein <1e-323 ○○○○○ 1.94 1.94261849351512
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2985  WP_000067419.1  E8XK86  hycG  255 aa formate hydrogenlyase subunit HycG 1.4e-5 ○○○○○ 1.94 1.94388761881936
Mycobacterium avium subsp. paratuberculosis K10  MAP_0977  AAS03294.1  Q741W0  pks16  544 aa Pks16 0.02 ○○○○○ 1.94 1.94444565279054
Mycobacterium avium subsp. paratuberculosis K10  MAP_3636  AAS06186.1  Q73TT2  866 aa hypothetical protein 0.02 ○○○○○ 1.95 1.94593714132274
Mycobacterium avium subsp. paratuberculosis K10  MAP_0583  AAS02900.1  Q743K2  222 aa hypothetical protein 0.019 ○○○○○ 1.95 1.95106778331011
Escherichia coli M12  CO715_13715  ATI06669.1  153 aa aspartate carbamoyltransferase regulatory subunit 1.4e-5 ○○○○○ 1.95 1.95197397452681
Mycobacterium avium subsp. paratuberculosis K10  MAP_3675  AAS06225.1  Q73TP3  ilvB  506 aa IlvB_2 0.019 ○○○○○ 1.95 1.95259664278159
Streptococcus pyogenes M1 5448  SP5448_02135  WP_002983360.1  269 aa PTS mannose/fructose/sorbose transporter subunit IIC 0.017 ○○○○○ 1.95 1.95325920574865
Mycobacterium avium subsp. paratuberculosis K10  MAP_0300  AAS02617.1  Q744P1  424 aa hypothetical protein 0.019 ○○○○○ 1.95 1.95366199140946
Streptococcus pyogenes M1 5448  SP5448_03110  WP_002989018.1  131 aa hypothetical protein 0.016 ○○○○○ 1.95 1.95422054224671
Mycobacterium avium subsp. paratuberculosis K10  MAP_1481c  AAS03798.1  Q73ZX0  497 aa hypothetical protein 0.019 ○○○○○ 1.96 1.95672269959722
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2136  NP_231767.1  H9L4P6  351 aa sensory box sensor histidine kinase 0.0062 ○○○○○ 1.96 1.96217703167011
Mycobacterium avium subsp. paratuberculosis K10  MAP_2850c  AAS05167.1  Q73W11  68 aa hypothetical protein 0.019 ○○○○○ 1.96 1.96348113774701
Escherichia coli O157:H7 str. EDL933  Z2722  AAG56681.1  531 aa putative enzyme 0.026 ○○○○○ 1.96 1.96402442476394
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3857  WP_000093287.1  E8XFZ9  mtlA  638 aa PTS mannitol transporter subunit IICBA 9.0e-5 ○○○○○ 1.96 1.96459261786614
Mycobacterium avium subsp. paratuberculosis K10  MAP_1694  AAS04011.1  Q73ZA9  papA2  505 aa PapA2 0.019 ○○○○○ 1.97 1.96538693471803
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1029  AIK79652.1  198 aa phenylacetic acid degradation protein PaaY <1e-323 ○○○○○ 1.97 1.96657160102581
Mycobacterium avium subsp. paratuberculosis K10  MAP_1831c  AAS04148.1  Q73YX2  322 aa hypothetical protein 0.019 ○○○○○ 1.97 1.96672040016152
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1446  AIK80067.1  312 aa eamA-like transporter family protein <1e-323 ○○○○○ 1.97 1.96697914552445
Mycobacterium avium subsp. paratuberculosis K10  MAP_3413  AAS05963.1  Q73UF5  aldB  509 aa AldB 0.019 ○○○○○ 1.97 1.96840505009996
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0022  NP_229681.1  Q9KVW6  200 aa hypothetical protein 0.0012 ○○○○○ 1.97 1.96889102345571
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0039  WP_009881385.1  A1VX91  ilvD  558 aa dihydroxy-acid dehydratase 0.03 ○○○○○ 1.97 1.97102840564
Mycobacterium avium subsp. paratuberculosis K10  MAP_2767c  AAS05084.1  Q73W93  183 aa hypothetical protein 0.019 ○○○○○ 1.97 1.97245053632501
Vibrio parahaemolyticus RIMD 2210633  VP_1445  BAC59708.1  Q87PQ6  115 aa hypothetical protein 0.049 ○○○○○ 1.98 1.97615961805253
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3225  AIK81787.1  305 aa bacterial regulatory helix-turn-helix, lysR family protein 2.8e-12 ○○○○○ 1.98 1.97864095704209
Mycobacterium avium subsp. paratuberculosis K10  MAP_2146c  AAS04463.1  Q73Y12  436 aa hypothetical protein 0.018 ○○○○○ 1.98 1.98073563063595
Acinetobacter baumannii ATCC 17978  A1S_1895  ABO12322.2  A3M5X8  ispD  238 aa 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 0.018 ○○○○○ 1.98 1.98219901562507
Acinetobacter baumannii ATCC 17978  A1S_1639  ABO12066.1  180 aa peptidyl-prolyl cis-trans isomerase precursor 0.017 ○○○○○ 1.99 1.98583254134361
Streptococcus pyogenes M1 5448  SP5448_01820  WP_011285698.1  150 aa transcription antitermination factor NusB 0.011 ○○○○○ 1.99 1.98690598318092
Porphyromonas gingivalis ATCC 33277  PGN_0295  WP_012457402.1  B2RHG9  293 aa hypothetical protein <1e-323 ○○○○○ 1.99 1.98782061105309
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0364  WP_002868914.1  A0A0H3PAX5  335 aa nucleoside hydrolase 0.029 ○○○○○ 1.99 1.9889618179
Mycobacterium avium subsp. paratuberculosis K10  MAP_1194c  AAS03511.1  Q740Z8  258 aa hypothetical protein 0.018 ○○○○○ 1.99 1.98974300674002
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1011  AIK79634.1  476 aa amino acid permease family protein <1e-323 ○○○○○ 1.99 1.99025339605214
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1628  WP_002868888.1  A0A0H3PB32  328 aa hypothetical protein 0.029 ○○○○○ 1.99 1.99074054366
Mycobacterium avium subsp. paratuberculosis K10  MAP_1649c  AAS03966.1  Q73ZF4  256 aa hypothetical protein 0.018 ○○○○○ 2 1.99542730219576
Mycobacterium avium subsp. paratuberculosis K10  MAP_0230  AAS02547.1  Q745M1  embR  379 aa EmbR_1 0.018 ○○○○○ 2 1.99576829606828
Escherichia coli M12  CO715_02870  ATI04772.1  278 aa ethanolamine utilization protein EutJ 2.1e-6 ○○○○○ 2 1.99578963751907
Mycobacterium avium subsp. paratuberculosis K10  MAP_2317c  AAS04634.1  Q73XJ2  449 aa hypothetical protein 0.018 ○○○○○ 2 1.99793918706424
Streptococcus pyogenes M1 5448  SP5448_05485  WP_010922281.1  200 aa GTP cyclohydrolase I FolE 0.047 ○○○○○ 2 1.9984420211577
Mycobacterium avium subsp. paratuberculosis K10  MAP_1791  AAS04108.1  Q73Z12  norQ  264 aa NorQ 0.018 ○○○○○ 2 1.99860421218359
Mycobacterium avium subsp. paratuberculosis K10  MAP_4025  AAS06575.1  Q73SP8  ccsB  325 aa CcsB 0.018 ○○○○○ 2 1.99917509854888
Mycobacterium avium subsp. paratuberculosis K10  MAP_0113  AAS02430.1  Q745C0  416 aa hypothetical protein 0.018 ○○○○○ 2 1.9994747973955
Mycobacterium avium subsp. paratuberculosis K10  MAP_3698c  AAS06248.1  Q73TM0  647 aa hypothetical protein 0.018 ○○○○○ 2 2.00249530253922
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0382  WP_002857587.1  A0A0H3PBR9  ccpA-2  341 aa cytochrome-c peroxidase 0.028 ○○○○○ 2 2.00314724547
Streptococcus pyogenes M1 5448  SP5448_01765  WP_002983113.1  97 aa hypothetical protein 0.042 ○○○○○ 2.01 2.00901672263641
Mycobacterium avium subsp. paratuberculosis K10  MAP_1214  AAS03531.1  Q740X8  377 aa hypothetical protein 0.017 ○○○○○ 2.01 2.00904254352382
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1242  AIK79865.1  389 aa bacterial extracellular solute-binding family protein <1e-323 ○○○○○ 2.01 2.01028780156202
Mycobacterium avium subsp. paratuberculosis K10  MAP_3351c  AAS05901.1  Q73UL5  254 aa hypothetical protein 0.017 ○○○○○ 2.01 2.0123559511604
Mycobacterium avium subsp. paratuberculosis K10  MAP_0385  AAS02702.1  Q744F6  197 aa hypothetical protein 0.017 ○○○○○ 2.01 2.0123711590984
Streptococcus pyogenes M1 5448  SP5448_06025  WP_002984913.1  217 aa uracil-DNA glycosylase 0.024 ○○○○○ 2.01 2.01382340512673
Vibrio parahaemolyticus RIMD 2210633  VP_0707  BAC58970.1  Q87RS0  38 aa hypothetical protein 0.046 ○○○○○ 2.01 2.01393407638878
Mycobacterium avium subsp. paratuberculosis K10  MAP_2726c  AAS05043.1  Q73WD4  fdxA  118 aa FdxA 0.017 ○○○○○ 2.01 2.01474506376323
Mycobacterium avium subsp. paratuberculosis K10  MAP_0805c  AAS03122.1  Q742N0  250 aa hypothetical protein 0.017 ○○○○○ 2.02 2.01525367927822
Escherichia coli O157:H7 str. EDL933  Z0634  AAG54839.1  720 aa putative cytoplasmic membrane export protein 0.023 ○○○○○ 2.02 2.01641543354249
Mycobacterium avium subsp. paratuberculosis K10  MAP_0933  AAS03250.1  Q742A4  409 aa hypothetical protein 0.017 ○○○○○ 2.02 2.01717969969398
Acinetobacter baumannii ATCC 17978  A1S_0592  ABO11043.2  A3M299  thrS  640 aa threonyl-tRNA synthetase 0.016 ○○○○○ 2.02 2.01824002795094
Mycobacterium avium subsp. paratuberculosis K10  MAP_0858  AAS03175.1  Q742H7  182 aa hypothetical protein 0.017 ○○○○○ 2.02 2.01891422368597
Mycobacterium avium subsp. paratuberculosis K10  MAP_2853c  AAS05170.1  Q73W08  141 aa hypothetical protein 0.017 ○○○○○ 2.02 2.01995419603444
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0649  WP_002869363.1  A0A0H3PBK6  215 aa M48 family peptidase 0.027 ○○○○○ 2.02 2.01999996362
Mycobacterium avium subsp. paratuberculosis K10  MAP_4206c  AAS06756.1  Q73S70  832 aa hypothetical protein 0.017 ○○○○○ 2.02 2.02004027072453
Mycobacterium avium subsp. paratuberculosis K10  MAP_1058  AAS03375.1  Q741N2  268 aa hypothetical protein 0.017 ○○○○○ 2.02 2.02082588524831
Escherichia coli M12  CO715_23135  ATI08364.1  85 aa hypothetical protein 1.1e-53 ○○○○○ 2.02 2.02082715922894
Mycobacterium avium subsp. paratuberculosis K10  MAP_1523  AAS03840.1  Q73ZS8  106 aa hypothetical protein 0.017 ○○○○○ 2.02 2.021614555119
Mycobacterium avium subsp. paratuberculosis K10  MAP_1332  AAS03649.1  Q740L8  pknF  620 aa PknF 0.017 ○○○○○ 2.02 2.02168286342444
Streptococcus pyogenes M1 5448  SP5448_05020  WP_010922336.1  477 aa hypothetical protein 0.03 ○○○○○ 2.02 2.02247543360932
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1358  AIK79981.1  167 aa glycine-zipper containing OmpA-like membrane domain protein 0.0004 ○○○○○ 2.02 2.02464684004448
Mycobacterium avium subsp. paratuberculosis K10  MAP_2854c  AAS05171.1  Q73W07  269 aa hypothetical protein 0.017 ○○○○○ 2.03 2.02531851775791
Mycobacterium avium subsp. paratuberculosis K10  MAP_3285c  AAS05835.1  Q73UT1  354 aa hypothetical protein 0.017 ○○○○○ 2.03 2.02667492883293
Escherichia coli O157:H7 str. EDL933  Z0344  AAG54603.1  92 aa hypothetical protein 0.023 ○○○○○ 2.03 2.02869563369005
Mycobacterium avium subsp. paratuberculosis K10  MAP_3801  AAS06351.1  Q73TB7  488 aa hypothetical protein 0.017 ○○○○○ 2.03 2.02890313657918
Porphyromonas gingivalis ATCC 33277  PGN_1115  WP_012458040.1  B2RJT9  369 aa hemagglutinin 0.0046 ○○○○○ 2.03 2.0294043900591
Mycobacterium avium subsp. paratuberculosis K10  MAP_0205  AAS02522.1  Q745K2  252 aa hypothetical protein 0.017 ○○○○○ 2.03 2.02971570033812
Acinetobacter baumannii ATCC 17978  A1S_0644  ABO11093.2  272 aa hypothetical protein 8.6e-19 ○○○○○ 2.03 2.03242148645631
Mycobacterium avium subsp. paratuberculosis K10  MAP_2846c  AAS05163.1  Q73W15  miaB  517 aa hypothetical protein 0.017 ○○○○○ 2.03 2.03284819695564
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1043  AIK79666.1  755 aa primary amine oxidase <1e-323 ○○○○○ 2.03 2.03332203632494
Streptococcus pyogenes M1 5448  SP5448_06020  WP_011285490.1  422 aa dihydroorotase 0.016 ○○○○○ 2.03 2.03401147158609
Vibrio parahaemolyticus RIMD 2210633  VP_0763  BAC59026.1  Q87RL5  39 aa hypothetical protein 0.043 ○○○○○ 2.04 2.03918541671577
Haemophilus influenzae Rd KW20  HI_0579  NP_438737.1  P43925  fusA  700 aa elongation factor G 0.042 ○○○○○ 2.04 2.03923473590019
Serratia marcescens Strain UMH9  BVG96_04230  ASL96855.1  180 aa type-1 fimbrial protein subunit 0.031 ○○○○○ 2.04 2.03940949782284
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2131  NP_231762.1  Q9KQ70  270 aa flagellar assembly protein H 1.2e-5 ○○○○○ 2.04 2.04080186925557
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1355  WP_002856036.1  A0A0H3PDS7  73 aa hypothetical protein 0.026 ○○○○○ 2.04 2.04377693619
Acinetobacter baumannii ATCC 17978  A1S_0998  ABO11430.2  A3M3D6  lysS  509 aa lysyl-tRNA-synthase 0.012 ○○○○○ 2.04 2.0438436111131
Mycobacterium avium subsp. paratuberculosis K10  MAP_3385  AAS05935.1  Q73UI3  304 aa hypothetical protein 0.016 ○○○○○ 2.04 2.04404344021847
Retrieved entries 35,701–35,800 out of 36,363 total in 1584.5 ms (Link to these results)